GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen October 2, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome February 28, 2024 (Version 87)
UniProt December 27, 2023
Protein Name UniProt ID Gene Symbol Species Taxonomy ID No. of Glycosylation Sites No. of GlyTouCan IDs GO Labels GO IDs
  • B3GAT3
9544
1
  • Golgi membrane
  • galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
  • metal ion binding
  • GO:0000139
  • GO:0015018
  • GO:0046872
  • Cacna1g
52777
1
  • metal ion binding
  • regulation of monoatomic ion transmembrane transport
  • voltage-gated calcium channel activity
  • voltage-gated calcium channel complex
  • GO:0005245
  • GO:0005891
  • GO:0034765
  • GO:0046872
  • RHO
9615
2
  • G protein-coupled receptor activity
  • Golgi apparatus
  • adaptation of rhodopsin mediated signaling
  • cell-cell junction
  • detection of temperature stimulus involved in thermoception
  • gene expression
  • metal ion binding
  • photoreceptor activity
  • photoreceptor cell maintenance
  • photoreceptor disc membrane
  • photoreceptor inner segment membrane
  • photoreceptor outer segment membrane
  • rod bipolar cell differentiation
  • rod photoreceptor outer segment
  • sperm head plasma membrane
  • sperm midpiece
  • thermotaxis
  • visual perception
  • GO:0004930
  • GO:0005794
  • GO:0005911
  • GO:0007601
  • GO:0009881
  • GO:0010467
  • GO:0016062
  • GO:0042622
  • GO:0043052
  • GO:0045494
  • GO:0046872
  • GO:0050960
  • GO:0060342
  • GO:0097225
  • GO:0097381
  • GO:0120200
  • GO:1904389
  • GO:1990913
  • M2
1730983
1
  • host cell plasma membrane
  • membrane
  • monoatomic ion channel activity
  • protein complex oligomerization
  • proton transmembrane transporter activity
  • suppression by virus of host autophagy
  • virion membrane
  • virus-mediated pore formation in host cell membrane
  • GO:0005216
  • GO:0015078
  • GO:0016020
  • GO:0020002
  • GO:0039521
  • GO:0039707
  • GO:0051259
  • GO:0055036
  • TEA_011026
542762
1
  • apoplast
  • cell wall biogenesis
  • cell wall organization
  • fruit ripening
  • hydrolase activity, hydrolyzing O-glycosyl compounds
  • xyloglucan metabolic process
  • xyloglucan:xyloglucosyl transferase activity
  • GO:0004553
  • GO:0009835
  • GO:0010411
  • GO:0016762
  • GO:0042546
  • GO:0048046
  • GO:0071555
  • Asgr1
10090
3
  • asialoglycoprotein receptor activity
  • cellular response to extracellular stimulus
  • external side of plasma membrane
  • fucose binding
  • identical protein binding
  • mannose binding
  • metal ion binding
  • GO:0004873
  • GO:0005537
  • GO:0009897
  • GO:0031668
  • GO:0042802
  • GO:0042806
  • GO:0046872
  • OFUT6
3702
4
  • fucose metabolic process
  • glycosyltransferase activity
  • membrane
  • GO:0006004
  • GO:0016020
  • GO:0016757
  • AGTR1
9031
4
  • G protein-coupled receptor signaling pathway
  • Rho protein signal transduction
  • angiotensin type I receptor activity
  • angiotensin type II receptor activity
  • bradykinin receptor binding
  • calcium-mediated signaling
  • cell chemotaxis
  • inflammatory response
  • kidney development
  • maintenance of blood vessel diameter homeostasis by renin-angiotensin
  • plasma membrane
  • positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
  • positive regulation of cytosolic calcium ion concentration
  • positive regulation of macrophage derived foam cell differentiation
  • positive regulation of protein metabolic process
  • protein heterodimerization activity
  • regulation of vasoconstriction
  • viral entry into host cell
  • GO:0001596
  • GO:0001822
  • GO:0002034
  • GO:0004945
  • GO:0005886
  • GO:0006954
  • GO:0007186
  • GO:0007204
  • GO:0007266
  • GO:0010744
  • GO:0019229
  • GO:0019722
  • GO:0031711
  • GO:0046718
  • GO:0046982
  • GO:0051247
  • GO:0060326
  • GO:1903589
  • Atp7a
10116
1
  • ATP binding
  • ATP hydrolysis activity
  • ATP metabolic process
  • Golgi apparatus
  • P-type divalent copper transporter activity
  • P-type monovalent copper transporter activity
  • T-helper cell differentiation
  • apical plasma membrane
  • axon
  • basolateral plasma membrane
  • blood vessel development
  • blood vessel remodeling
  • brush border membrane
  • cartilage development
  • catecholamine metabolic process
  • cell leading edge
  • cellular response to amino acid stimulus
  • cellular response to antibiotic
  • cellular response to cadmium ion
  • cellular response to cobalt ion
  • cellular response to copper ion
  • cellular response to hypoxia
  • cellular response to iron ion
  • cellular response to lead ion
  • cellular response to platelet-derived growth factor stimulus
  • central nervous system neuron development
  • cerebellar Purkinje cell differentiation
  • collagen fibril organization
  • copper ion binding
  • copper ion export
  • copper ion homeostasis
  • copper ion import
  • copper ion transmembrane transporter activity
  • copper ion transport
  • copper-dependent protein binding
  • cuprous ion binding
  • cytoplasmic vesicle
  • dendrite
  • dendrite morphogenesis
  • detoxification of copper ion
  • dopamine metabolic process
  • early endosome membrane
  • elastic fiber assembly
  • elastin biosynthetic process
  • epinephrine metabolic process
  • establishment of localization in cell
  • extracellular matrix organization
  • female pregnancy
  • hair follicle morphogenesis
  • hindlimb morphogenesis
  • in utero embryonic development
  • intracellular copper ion homeostasis
  • lactation
  • late endosome
  • liver development
  • locomotory behavior
  • lung alveolus development
  • melanosome membrane
  • membrane
  • microvillus
  • mitochondrion organization
  • negative regulation of catecholamine metabolic process
  • negative regulation of iron ion transmembrane transport
  • negative regulation of neuron apoptotic process
  • neuron apoptotic process
  • neuron cellular homeostasis
  • neuron projection
  • neuron projection morphogenesis
  • neuronal cell body
  • norepinephrine biosynthetic process
  • norepinephrine metabolic process
  • perikaryon
  • perinuclear region of cytoplasm
  • pigmentation
  • plasma membrane
  • positive regulation of cell size
  • positive regulation of epithelial cell proliferation
  • positive regulation of lamellipodium assembly
  • positive regulation of melanin biosynthetic process
  • positive regulation of response to wounding
  • positive regulation of tyrosinase activity
  • positive regulation of vascular associated smooth muscle cell migration
  • postsynaptic density
  • protein-folding chaperone binding
  • pyramidal neuron development
  • regulation of gene expression
  • regulation of oxidative phosphorylation
  • release of cytochrome c from mitochondria
  • removal of superoxide radicals
  • response to copper ion
  • response to iron(III) ion
  • response to lead ion
  • response to manganese ion
  • response to zinc ion
  • secretory granule
  • serotonin metabolic process
  • skin development
  • small GTPase binding
  • superoxide dismutase copper chaperone activity
  • trans-Golgi network
  • trans-Golgi network membrane
  • trans-Golgi network transport vesicle
  • tryptophan metabolic process
  • tyrosine metabolic process
  • GO:0001568
  • GO:0001701
  • GO:0001836
  • GO:0001889
  • GO:0001974
  • GO:0002082
  • GO:0005375
  • GO:0005507
  • GO:0005524
  • GO:0005770
  • GO:0005794
  • GO:0005802
  • GO:0005886
  • GO:0005902
  • GO:0006568
  • GO:0006570
  • GO:0006584
  • GO:0006825
  • GO:0006878
  • GO:0007005
  • GO:0007565
  • GO:0007595
  • GO:0007626
  • GO:0010041
  • GO:0010042
  • GO:0010043
  • GO:0010273
  • GO:0010288
  • GO:0010468
  • GO:0010592
  • GO:0014069
  • GO:0015677
  • GO:0016020
  • GO:0016323
  • GO:0016324
  • GO:0016532
  • GO:0016887
  • GO:0019430
  • GO:0021702
  • GO:0021860
  • GO:0021954
  • GO:0030140
  • GO:0030141
  • GO:0030198
  • GO:0030199
  • GO:0030424
  • GO:0030425
  • GO:0031069
  • GO:0031252
  • GO:0031267
  • GO:0031410
  • GO:0031526
  • GO:0031901
  • GO:0032588
  • GO:0032767
  • GO:0032773
  • GO:0033162
  • GO:0034760
  • GO:0035137
  • GO:0036120
  • GO:0042093
  • GO:0042414
  • GO:0042415
  • GO:0042417
  • GO:0042421
  • GO:0042428
  • GO:0043005
  • GO:0043025
  • GO:0043204
  • GO:0043473
  • GO:0043524
  • GO:0043588
  • GO:0043682
  • GO:0045793
  • GO:0045914
  • GO:0046034
  • GO:0046688
  • GO:0048023
  • GO:0048251
  • GO:0048286
  • GO:0048471
  • GO:0048812
  • GO:0048813
  • GO:0050679
  • GO:0051087
  • GO:0051216
  • GO:0051402
  • GO:0051542
  • GO:0051649
  • GO:0055070
  • GO:0060003
  • GO:0070050
  • GO:0071230
  • GO:0071236
  • GO:0071276
  • GO:0071279
  • GO:0071280
  • GO:0071281
  • GO:0071284
  • GO:0071456
  • GO:0140581
  • GO:1903036
  • GO:1903136
  • GO:1904754
  • M2
1932817
1
  • host cell plasma membrane
  • membrane
  • monoatomic ion channel activity
  • protein complex oligomerization
  • proton transmembrane transporter activity
  • suppression by virus of host autophagy
  • virion membrane
  • virus-mediated pore formation in host cell membrane
  • GO:0005216
  • GO:0015078
  • GO:0016020
  • GO:0020002
  • GO:0039521
  • GO:0039707
  • GO:0051259
  • GO:0055036
Displaying entries 31 - 40 of 120208 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01