GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect April 19, 2023
GlycoProtDB October 1, 2021
GlyGen October 2, 2023
Human Protein Atlas June 19, 2023 (Protein Atlas version 23)
MCAW-DB July 10, 2019
The O-GlcNAc Database April 10, 2023 (v1.3)
Reactome February 28, 2024 (Version 87)
UniProt December 27, 2023
Protein Name UniProt ID Gene Symbol Species Taxonomy ID No. of Glycosylation Sites No. of GlyTouCan IDs GO Labels GO IDs
  • Ighm
10116
1
  • GPR107
9606
4
2
  • Golgi apparatus
  • clathrin heavy chain binding
  • clathrin-coated vesicle
  • clathrin-dependent endocytosis
  • early endosome
  • membrane
  • nucleoplasm
  • plasma membrane
  • GO:0005654
  • GO:0005769
  • GO:0005794
  • GO:0005886
  • GO:0016020
  • GO:0030136
  • GO:0032050
  • GO:0072583
  • Gns
10090
5
7
  • N-acetylglucosamine-6-sulfatase activity
  • glycosaminoglycan binding
  • keratan sulfate catabolic process
  • lysosome
  • metal ion binding
  • sulfate binding
  • sulfuric ester hydrolase activity
  • GO:0005539
  • GO:0005764
  • GO:0008449
  • GO:0008484
  • GO:0042340
  • GO:0043199
  • GO:0046872
  • M2
1823779
1
  • host cell plasma membrane
  • membrane
  • monoatomic ion channel activity
  • protein complex oligomerization
  • proton transmembrane transporter activity
  • suppression by virus of host autophagy
  • virion membrane
  • virus-mediated pore formation in host cell membrane
  • GO:0005216
  • GO:0015078
  • GO:0016020
  • GO:0020002
  • GO:0039521
  • GO:0039707
  • GO:0051259
  • GO:0055036
  • SEMA3F
9606
3
5
  • axon extension involved in axon guidance
  • axon guidance
  • branchiomotor neuron axon guidance
  • chemorepellent activity
  • extracellular space
  • facial nerve structural organization
  • glutamatergic synapse
  • negative chemotaxis
  • negative regulation of axon extension involved in axon guidance
  • nerve development
  • neural crest cell migration
  • neural crest cell migration involved in autonomic nervous system development
  • positive regulation of cell migration
  • regulation of postsynapse organization
  • semaphorin receptor binding
  • semaphorin-plexin signaling pathway
  • semaphorin-plexin signaling pathway involved in axon guidance
  • semaphorin-plexin signaling pathway involved in neuron projection guidance
  • sympathetic ganglion development
  • sympathetic neuron projection extension
  • sympathetic neuron projection guidance
  • trigeminal nerve structural organization
  • ventral trunk neural crest cell migration
  • GO:0001755
  • GO:0005615
  • GO:0007411
  • GO:0021612
  • GO:0021637
  • GO:0021675
  • GO:0021785
  • GO:0030215
  • GO:0030335
  • GO:0036486
  • GO:0045499
  • GO:0048843
  • GO:0048846
  • GO:0050919
  • GO:0061549
  • GO:0071526
  • GO:0097490
  • GO:0097491
  • GO:0098978
  • GO:0099175
  • GO:1901166
  • GO:1902285
  • GO:1902287
  • P2RX3
10141
1
  • ATP binding
  • Schaffer collateral - CA1 synapse
  • axon
  • behavioral response to pain
  • cellular response to ATP
  • establishment of localization in cell
  • extracellularly ATP-gated monoatomic cation channel activity
  • hippocampal mossy fiber to CA3 synapse
  • inorganic cation transmembrane transport
  • neuromuscular synaptic transmission
  • peristalsis
  • plasma membrane
  • postsynapse
  • protein homotrimerization
  • purinergic nucleotide receptor activity
  • receptor complex
  • regulation of synaptic plasticity
  • response to carbohydrate
  • response to cold
  • response to heat
  • response to hypoxia
  • response to mechanical stimulus
  • sensory perception of taste
  • urinary bladder smooth muscle contraction
  • GO:0001614
  • GO:0001666
  • GO:0004931
  • GO:0005524
  • GO:0005886
  • GO:0007274
  • GO:0009408
  • GO:0009409
  • GO:0009612
  • GO:0009743
  • GO:0014832
  • GO:0030424
  • GO:0030432
  • GO:0043235
  • GO:0048167
  • GO:0048266
  • GO:0050909
  • GO:0051649
  • GO:0070207
  • GO:0071318
  • GO:0098662
  • GO:0098685
  • GO:0098686
  • GO:0098794
  • NSP4
10941
2
  • extracellular region
  • host caveola
  • host cell rough endoplasmic reticulum membrane
  • induction by virus of host autophagy
  • membrane
  • metal ion binding
  • monoatomic ion channel activity
  • protein complex oligomerization
  • toxin activity
  • virus-mediated pore formation in host cell membrane
  • GO:0005216
  • GO:0005576
  • GO:0016020
  • GO:0039520
  • GO:0039707
  • GO:0044155
  • GO:0044169
  • GO:0046872
  • GO:0051259
  • GO:0090729
  • LOC103507213
121845
1
  • Golgi membrane
  • galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
  • metal ion binding
  • GO:0000139
  • GO:0015018
  • GO:0046872
  • IL13
9544
4
  • cytokine activity
  • cytokine receptor binding
  • extracellular space
  • immune response
  • GO:0005125
  • GO:0005126
  • GO:0005615
  • GO:0006955
  • Bace2
64802
1
  • aspartic-type endopeptidase activity
  • endosome
  • membrane
  • proteolysis
  • GO:0004190
  • GO:0005768
  • GO:0006508
  • GO:0016020
Displaying entries 1 - 10 of 120208 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01