GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 2, 2023
Human Protein Atlas	June 19, 2023 (Protein Atlas version 23)
MCAW-DB	July 10, 2019
The O-GlcNAc Database	April 10, 2023 (v1.3)
Reactome	February 28, 2024 (Version 87)
UniProt	December 27, 2023

Protein Name	UniProt ID	Gene Symbol	Species	Taxonomy ID	No. of Glycosylation Sites ▼	GO Labels	GO IDs
Mucin-4	Q99102	MUC4	Homo sapiens	9606	547	ErbB-2 class receptor binding Golgi lumen cell-matrix adhesion extracellular exosome extracellular matrix extracellular matrix constituent, lubricant activity extracellular space maintenance of gastrointestinal epithelium membrane plasma membrane vesicle	GO:0005176 GO:0005615 GO:0005796 GO:0005886 GO:0007160 GO:0016020 GO:0030197 GO:0030277 GO:0031012 GO:0031982 GO:0070062
Versican core protein	P13611	VCAN	Homo sapiens	9606	281	Golgi lumen calcium ion binding carbohydrate binding cell adhesion cell recognition central nervous system development collagen-containing extracellular matrix endoplasmic reticulum lumen extracellular matrix extracellular matrix structural constituent conferring compression resistance extracellular region extracellular space glial cell differentiation glial cell migration glycosaminoglycan binding hyaluronic acid binding interphotoreceptor matrix lysosomal lumen membrane osteoblast differentiation perineuronal net photoreceptor outer segment positive regulation of neuroblast proliferation skeletal system development synapse	GO:0001501 GO:0001649 GO:0001750 GO:0002052 GO:0005509 GO:0005539 GO:0005540 GO:0005576 GO:0005615 GO:0005788 GO:0005796 GO:0007155 GO:0007417 GO:0008037 GO:0008347 GO:0010001 GO:0016020 GO:0030021 GO:0030246 GO:0031012 GO:0033165 GO:0043202 GO:0045202 GO:0062023 GO:0072534
Mucin-4	Q8JZM8	Muc4	Mus musculus	10090	266	ErbB-2 class receptor binding apical plasma membrane cell-matrix adhesion collagen-containing extracellular matrix extracellular space hematopoietic progenitor cell differentiation maintenance of gastrointestinal epithelium microvillus membrane negative regulation of T cell mediated cytotoxicity directed against tumor cell target negative regulation of apoptotic process negative regulation of cell-cell adhesion negative regulation of cell-matrix adhesion protein-containing complex protein-containing complex binding	GO:0001953 GO:0002244 GO:0002853 GO:0005176 GO:0005615 GO:0007160 GO:0016324 GO:0022408 GO:0030277 GO:0031528 GO:0032991 GO:0043066 GO:0044877 GO:0062023
Protein bassoon	O88737	Bsn	Mus musculus	10090	246	GABA-ergic synapse Golgi-associated vesicle Schaffer collateral - CA1 synapse axo-dendritic transport axon axon cytoplasm cell cortex cell surface cochlear hair cell ribbon synapse cytoskeleton of presynaptic active zone cytosol dendrite dynein light chain binding excitatory synapse extrinsic component of membrane glutamatergic synapse hippocampal mossy fiber to CA3 synapse inhibitory synapse metal ion binding neuron projection terminus neuronal cell body piccolo-bassoon transport vesicle postsynaptic density presynapse presynapse to nucleus signaling pathway presynaptic active zone presynaptic active zone assembly presynaptic active zone cytoplasmic component protein localization to synapse regulation of synaptic vesicle cycle retrograde axonal transport ribbon synapse structural constituent of presynaptic active zone synapse synapse organization synaptic vesicle synaptic vesicle clustering trans-Golgi network transcription corepressor binding	GO:0001222 GO:0005798 GO:0005802 GO:0005829 GO:0005938 GO:0008021 GO:0008088 GO:0008090 GO:0009986 GO:0014069 GO:0019898 GO:0030424 GO:0030425 GO:0035418 GO:0043025 GO:0044306 GO:0045202 GO:0045503 GO:0046872 GO:0048786 GO:0048788 GO:0050808 GO:0060076 GO:0060077 GO:0097091 GO:0097470 GO:0098683 GO:0098685 GO:0098686 GO:0098693 GO:0098793 GO:0098831 GO:0098882 GO:0098978 GO:0098982 GO:0099526 GO:1904071 GO:1904115 GO:1990257
Mucin-16	Q8WXI7	MUC16	Homo sapiens	9606	222	Golgi lumen cell adhesion external side of plasma membrane extracellular exosome plasma membrane vesicle	GO:0005796 GO:0005886 GO:0007155 GO:0009897 GO:0031982 GO:0070062
Nuclear pore complex protein Nup214	P35658	NUP214	Homo sapiens	9606	215	RNA export from nucleus cytoplasmic side of nuclear pore cytosol mRNA export from nucleus nuclear envelope nuclear export signal receptor activity nuclear localization sequence binding nuclear pore nucleocytoplasmic transport nucleoplasm protein export from nucleus protein import into nucleus regulation of cell cycle regulation of nucleocytoplasmic transport structural constituent of nuclear pore	GO:0005049 GO:0005635 GO:0005643 GO:0005654 GO:0005829 GO:0006405 GO:0006406 GO:0006606 GO:0006611 GO:0006913 GO:0008139 GO:0017056 GO:0046822 GO:0051726 GO:1990876
Host cell factor 1	P51610	HCFC1	Homo sapiens	9606	199	DNA-binding transcription factor binding MLL1 complex MLL1/2 complex NSL complex Set1C/COMPASS complex cadherin binding cell cycle chromatin binding chromatin remodeling cytoplasm histone acetyltransferase complex histone methyltransferase complex identical protein binding membrane negative regulation of transcription by RNA polymerase II neuronal cell body nucleoplasm nucleus obsolete regulation of dosage compensation by inactivation of X chromosome positive regulation of DNA-templated transcription positive regulation of cell cycle positive regulation of gene expression positive regulation of histone H3-K4 methylation positive regulation of transcription by RNA polymerase II protein stabilization protein-containing complex protein-macromolecule adaptor activity regulation of DNA-templated transcription regulation of protein-containing complex assembly release from viral latency transcription coactivator activity	GO:0000122 GO:0000123 GO:0003682 GO:0003713 GO:0005634 GO:0005654 GO:0005737 GO:0006338 GO:0006355 GO:0007049 GO:0010628 GO:0016020 GO:0019046 GO:0030674 GO:0032991 GO:0035097 GO:0042802 GO:0043025 GO:0043254 GO:0044545 GO:0044665 GO:0045296 GO:0045787 GO:0045893 GO:0045944 GO:0048188 GO:0050821 GO:0051571 GO:0071339 GO:0140297 GO:1900095
Nuclear pore complex protein Nup153	P49790	NUP153	Homo sapiens	9606	153	DNA binding RNA export from nucleus cytosol host cell identical protein binding mRNA transport membrane metal ion binding negative regulation of RNA export from nucleus nuclear envelope nuclear inclusion body nuclear localization sequence binding nuclear membrane nuclear periphery nuclear pore nuclear pore complex assembly nuclear pore nuclear basket nucleocytoplasmic transport nucleolus nucleoplasm protein import into nucleus protein-membrane adaptor activity structural constituent of nuclear pore viral entry into host cell viral penetration into host nucleus	GO:0003677 GO:0005635 GO:0005643 GO:0005654 GO:0005730 GO:0005829 GO:0006405 GO:0006606 GO:0006913 GO:0008139 GO:0016020 GO:0017056 GO:0031965 GO:0034399 GO:0042405 GO:0042802 GO:0043495 GO:0043657 GO:0044615 GO:0046718 GO:0046832 GO:0046872 GO:0051028 GO:0051292 GO:0075732
Protein piccolo	Q9QYX7	Pclo	Mus musculus	10090	151	GABA-ergic synapse Golgi-associated vesicle axon calcium ion binding calcium-dependent phospholipid binding cone cell pedicle cytoskeleton of presynaptic active zone cytoskeleton organization dendrite glutamatergic synapse growth cone inhibitory synapse insulin secretion maintenance of presynaptic active zone structure modulation of excitatory postsynaptic potential neuromuscular junction neuronal cell body parallel fiber to Purkinje cell synapse perinuclear region of cytoplasm positive regulation of synaptic vesicle recycling postsynaptic density presynapse to nucleus signaling pathway presynaptic active zone presynaptic active zone assembly presynaptic active zone cytoplasmic component profilin binding protein localization to synapse regulation of endosome size regulation of exocytosis ribbon synapse rod spherule structural constituent of presynaptic active zone synapse synapse organization synaptic vesicle clustering synaptic vesicle targeting terminal bouton trans-Golgi network transcription corepressor binding	GO:0001222 GO:0005509 GO:0005522 GO:0005544 GO:0005798 GO:0005802 GO:0007010 GO:0014069 GO:0016080 GO:0017157 GO:0030073 GO:0030424 GO:0030425 GO:0030426 GO:0031594 GO:0035418 GO:0043025 GO:0043195 GO:0044316 GO:0044317 GO:0045202 GO:0048471 GO:0048786 GO:0048788 GO:0048790 GO:0050808 GO:0051036 GO:0060077 GO:0097091 GO:0097470 GO:0098688 GO:0098815 GO:0098831 GO:0098882 GO:0098978 GO:0098982 GO:0099526 GO:1903423 GO:1904071
Colossin-A	Q54CU4	colA	Dictyostelium discoideum	44689	119	extracellular region	GO:0005576