GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen, GlyConnect, GlycoProtDB and The O-GlcNAc Database. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Source	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	June 4, 2024
The O-GlcNAc Database	June 3, 2024
UniProt	June 4, 2024

Displaying entries **1 - 25** of **213** in total

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UniProt ID	Protein Name	Gene Symbol	Organism	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	GlyTouCan ID	Disease Ontology	Disease Ontology ID	Gene Ontology	Gene Ontology ID
A0A3B3IUC4	Alpha-galactosidase	GLA	Homo sapiens (human)	9606	2	0				alpha-galactosidase activity glycoside catabolic process lipid metabolic process lysosome oligosaccharide metabolic process	GO:0004557 GO:0005764 GO:0006629 GO:0009311 GO:0016139
A2QAN3	Beta-galactosidase A	lacA	Aspergillus niger CBS 513.88	425011	11	0				beta-galactosidase activity carbohydrate metabolic process extracellular region lactose catabolic process oligosaccharide binding polysaccharide catabolic process vacuole	GO:0000272 GO:0004565 GO:0005576 GO:0005773 GO:0005975 GO:0005990 GO:0070492
Q4WX16	alpha-galactosidase	AFUA_3G07890	Aspergillus fumigatus Af293	330879	3	0				alpha-galactosidase activity membrane	GO:0004557 GO:0016020
Q5N8X6	Beta-galactosidase 3	Os01g0875500	Oryza sativa Japonica Group (Japanese rice)	39947	5	0				apoplast beta-galactosidase activity carbohydrate binding carbohydrate metabolic process vacuole	GO:0004565 GO:0005773 GO:0005975 GO:0030246 GO:0048046
P17050	Alpha-N-acetylgalactosaminidase	NAGA	Homo sapiens (human)	9606	5	95	G00155YT G00406II G01543ZX G02815KT G03005MJ G03275SD G03382KH G03842KQ G05724UK G05808PZ G06110VR G06356OH G06885ZB G07617FP G10486CT G11629QQ G12313PD G12849CJ G14389GM G14669DU G14889BN G15169WU G16828VN G17689DH G20210JR G20425TQ G20512LK G22310AV G22768VO G23863VK G23984SE G25637MV G29857RC G29880MM G31852PQ G33282QL G34617SM G36191CD G39188ZX G39595FH G41247ZX G44444MB G45209NR G45359RY G45546UR G48414YA G49108TO G50045TK G50282JC G51640FO G53280MT G55220VL G55521GY G57789QC G59575FI G60723SV G61138BO G61334IA G61962FK G63889NK G64394MX G66129DI G71470CO G72291OX G72735IY G72797UR G74239ZQ G74724QE G75594YZ G77252PU G78059CC G78790NZ G79809MM G80966KZ G81263BG G81349OI G82348BZ G82350PP G82463GQ G83161QT G83460ZZ G84349RE G84452RH G86357DX G90093AU G90448RI G90575OW G90717TP G91413ZX G92050GC G92275SC G93180LE G93284HQ G97183VL G97720QM	Clouston syndrome Fabry disease Kanzaki disease Schindler disease type 1 Unverricht-Lundborg syndrome acquired hyperkeratosis alternating hemiplegia of childhood autistic disorder autonomic neuropathy blepharospasm cancer cardiomyopathy cataract central nervous system disease central nervous system origin vertigo cerebral degeneration chylomicron retention disease congenital nystagmus dissociated nystagmus early myoclonic encephalopathy elephantiasis embryoma endomyocardial fibrosis epilepsy familial hypertrophic cardiomyopathy focal hand dystonia gallbladder disease hypertrophic cardiomyopathy hypertropia influenza intellectual disability learning disability lipid storage disease liver disease lymphedema mechanical strabismus nervous system disease neuroaxonal dystrophy neurodegeneration with brain iron accumulation 2a neuropathy ophthalmoplegia optic atrophy pathologic nystagmus peripheral nervous system disease sensorineural hearing loss spontaneous ocular nystagmus strabismus syndromic X-linked intellectual disability 94 trichomoniasis visual epilepsy	DOID:0050635 DOID:0050700 DOID:0050841 DOID:0060262 DOID:0060357 DOID:0060823 DOID:0080326 DOID:0110735 DOID:0112318 DOID:0112319 DOID:10003 DOID:1059 DOID:11504 DOID:11771 DOID:11832 DOID:11984 DOID:12849 DOID:12932 DOID:13072 DOID:13174 DOID:1443 DOID:14499 DOID:14693 DOID:162 DOID:1826 DOID:1947 DOID:2367 DOID:2479 DOID:308 DOID:331 DOID:3535 DOID:409 DOID:4766 DOID:4976 DOID:4977 DOID:529 DOID:539 DOID:540 DOID:5723 DOID:574 DOID:83 DOID:8469 DOID:863 DOID:870 DOID:8927 DOID:9306 DOID:9455 DOID:9649 DOID:9650 DOID:9837	alpha-N-acetylgalactosaminidase activity alpha-galactosidase activity carbohydrate catabolic process cytoplasm extracellular exosome glycolipid catabolic process glycoside catabolic process lysosome oligosaccharide metabolic process protein homodimerization activity	GO:0004557 GO:0005737 GO:0005764 GO:0008456 GO:0009311 GO:0016052 GO:0016139 GO:0019377 GO:0042803 GO:0070062
Q9SCU8	Beta-galactosidase 14	BGAL14	Arabidopsis thaliana (thale cress)	3702	4	0				apoplast beta-galactosidase activity carbohydrate binding carbohydrate metabolic process vacuole	GO:0004565 GO:0005773 GO:0005975 GO:0030246 GO:0048046
A1D1Z9	Probable beta-galactosidase A	lacA	Aspergillus fischeri NRRL 181	331117	8	0				beta-galactosidase activity extracellular region polysaccharide catabolic process vacuole	GO:0000272 GO:0004565 GO:0005576 GO:0005773
A2RB93	Probable arabinogalactan endo-beta-1,4-galactanase A	galA	Aspergillus niger CBS 513.88	425011	1	0				arabinogalactan endo-1,4-beta-galactosidase activity cell wall organization extracellular region glucosidase activity pectin catabolic process	GO:0005576 GO:0015926 GO:0031218 GO:0045490 GO:0071555
O81100	Beta-galactosidase	TBG4	Solanum lycopersicum (tomato)	4081	3	0				beta-galactosidase activity carbohydrate metabolic process vacuole	GO:0004565 GO:0005773 GO:0005975
B8N2I5	Probable beta-galactosidase C	lacC	Aspergillus flavus NRRL3357	332952	12	0				beta-galactosidase activity extracellular region polysaccharide catabolic process vacuole	GO:0000272 GO:0004565 GO:0005576 GO:0005773
Q10RB4	Beta-galactosidase 5	Os03g0165400	Oryza sativa Japonica Group (Japanese rice)	39947	2	0				apoplast beta-galactosidase activity carbohydrate binding carbohydrate metabolic process vacuole	GO:0004565 GO:0005773 GO:0005975 GO:0030246 GO:0048046
B0YEK2	Probable alpha-galactosidase D	aglD	Aspergillus fumigatus A1163	451804	6	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process polysaccharide catabolic process	GO:0000272 GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
Q0IZZ8	Beta-galactosidase 12	Os09g0539200	Oryza sativa Japonica Group (Japanese rice)	39947	4	0				apoplast beta-galactosidase activity carbohydrate binding carbohydrate metabolic process vacuole	GO:0004565 GO:0005773 GO:0005975 GO:0030246 GO:0048046
P06280	Alpha-galactosidase A	GLA	Homo sapiens (human)	9606	3	44	G00406II G00912UN G01937VC G05724UK G06110VR G06247RL G11870QZ G12313PD G14669DU G15169WU G23294PN G23719VF G27058EU G28681TP G29184RN G31852PQ G34989PA G37412TK G39188ZX G41247ZX G43669FQ G45395BF G46503DX G47012YE G47644PP G48414YA G49108TO G50282JC G62765YT G62894KT G70101JE G70232NH G72291OX G74724QE G75983OB G76417NN G80920RR G82463GQ G83460ZZ G90382BL G90575OW G92275SC G95995BI G96091TT	Fabry disease Gaucher's disease Goodpasture syndrome Horner's syndrome Laron syndrome Meckel syndrome Moyamoya disease Niemann-Pick disease Parkinson's disease 19A Parkinson's disease 23 Parkinson's disease 4 Parkinson's disease Riley-Day syndrome Takayasu's arteritis X-linked agammaglobulinemia Zollinger-Ellison syndrome achondroplasia acquired hyperkeratosis acute myocardial infarction allergic asthma anemia angiokeratoma anhidrosis antithrombin III deficiency anxiety disorder arthritis arthropathy asthma atrial fibrillation atrioventricular block autosomal dominant polycystic kidney disease bacterial vaginosis breast cancer breast fibrocystic disease brucellosis cancer cardiomyopathy cardiovascular system disease cataract central nervous system origin vertigo cerebral infarction cerebrovascular disease chronic kidney disease chronic obstructive pulmonary disease chylomicron retention disease congenital hypogammaglobulinemia congestive heart failure corneal dystrophy coronary thrombosis cystinuria depressive disorder diabetes insipidus diabetes mellitus diabetic ketoacidosis diarrhea disease of metabolism dysthymic disorder elephantiasis endomyocardial fibrosis epilepsy erythromelalgia essential hypertension familial hyperlipidemia familial hypertrophic cardiomyopathy familial mediterranean fever familial nephrotic syndrome fibromyalgia galactosemia generalized anxiety disorder glaucoma glomerulonephritis glucosephosphate dehydrogenase deficiency glycogen storage disease II glycogen storage disease IXa glycogen storage disease IXb glycogen storage disease IXc glycogen storage disease IXd glycogen storage disease Ia glycogen storage disease granulomatosis with polyangiitis heart disease hyperinsulinism hypertension hypertrophic cardiomyopathy 1 hypertrophic cardiomyopathy hypoglycemia hypohidrosis influenza inherited metabolic disorder interstitial nephritis intrinsic asthma keratosis follicularis kidney disease kidney failure late onset Parkinson's disease lipid storage disease lipoid nephrosis lung disease lymphedema lysosomal storage disease macrocytic anemia major depressive disorder melancholic depression mevalonic aciduria microglandular adenosis mitral valve insufficiency mitral valve prolapse mongolian spot multiple sclerosis myocardial infarction myositis nephritis nephrosis nephrotic syndrome neurohypophyseal diabetes insipidus neuropathy neurotic disorder obsolete melancholia obsolete type 1 diabetes mellitus 9 obstructive lung disease optic atrophy osteoarthritis papillary adenocarcinoma papillary renal cell carcinoma peripheral nervous system disease pneumonia polyarteritis nodosa polyneuropathy priapism protein C deficiency protein S deficiency proteinuria pseudoxanthoma elasticum pyelitis pyelonephritis pyoureter recurrent corneal erosion renal infectious disease sensorineural hearing loss sick sinus syndrome silent myocardial infarction sphingolipidosis thrombophilia thyroid gland papillary carcinoma transient cerebral ischemia tuberculosis type 1 diabetes mellitus 10 type 1 diabetes mellitus 11 type 1 diabetes mellitus 12 type 1 diabetes mellitus 13 type 1 diabetes mellitus 15 type 1 diabetes mellitus 17 type 1 diabetes mellitus 18 type 1 diabetes mellitus 19 type 1 diabetes mellitus 20 type 1 diabetes mellitus 21 type 1 diabetes mellitus 22 type 1 diabetes mellitus 23 type 1 diabetes mellitus 24 type 1 diabetes mellitus 2 type 1 diabetes mellitus 3 type 1 diabetes mellitus 4 type 1 diabetes mellitus 5 type 1 diabetes mellitus 6 type 1 diabetes mellitus 7 type 1 diabetes mellitus 8 type 1 diabetes mellitus type 2 diabetes mellitus uremia vaginitis vascular disease vertebrobasilar insufficiency visual epilepsy vitamin K deficiency bleeding vulvitis vulvovaginal candidiasis vulvovaginitis	DOID:0014667 DOID:0050452 DOID:0050700 DOID:0050778 DOID:0050782 DOID:0050820 DOID:0060224 DOID:0060357 DOID:0060891 DOID:0060892 DOID:0060895 DOID:0060896 DOID:0080326 DOID:0110307 DOID:0110741 DOID:0110742 DOID:0110743 DOID:0110744 DOID:0110745 DOID:0110746 DOID:0110747 DOID:0110748 DOID:0110749 DOID:0110750 DOID:0110751 DOID:0110752 DOID:0110753 DOID:0110754 DOID:0110755 DOID:0110756 DOID:0110757 DOID:0110758 DOID:0110759 DOID:0110760 DOID:0110761 DOID:0111040 DOID:0111041 DOID:0111042 DOID:0111043 DOID:10003 DOID:10354 DOID:1063 DOID:1074 DOID:10763 DOID:10825 DOID:10952 DOID:10966 DOID:11077 DOID:11155 DOID:11156 DOID:11249 DOID:114 DOID:11400 DOID:11486 DOID:11502 DOID:11541 DOID:11589 DOID:1168 DOID:11832 DOID:1184 DOID:11847 DOID:11984 DOID:12132 DOID:12139 DOID:12388 DOID:1287 DOID:12932 DOID:13003 DOID:13072 DOID:13099 DOID:13250 DOID:13884 DOID:1389 DOID:14177 DOID:14179 DOID:1425 DOID:14320 DOID:14330 DOID:14499 DOID:14504 DOID:1470 DOID:1595 DOID:1596 DOID:1612 DOID:162 DOID:1686 DOID:178 DOID:1826 DOID:1837 DOID:1926 DOID:1927 DOID:2018 DOID:2030 DOID:2170 DOID:224 DOID:2272 DOID:2273 DOID:2320 DOID:2355 DOID:2361 DOID:2377 DOID:2451 DOID:2452 DOID:2479 DOID:2508 DOID:2527 DOID:2566 DOID:2590 DOID:2734 DOID:2738 DOID:2744 DOID:2747 DOID:2749 DOID:2752 DOID:2841 DOID:2848 DOID:2862 DOID:2921 DOID:2987 DOID:3083 DOID:3112 DOID:3211 DOID:3385 DOID:3526 DOID:3755 DOID:3756 DOID:381 DOID:3901 DOID:3969 DOID:399 DOID:4465 DOID:4480 DOID:4676 DOID:4702 DOID:479 DOID:4964 DOID:4976 DOID:4977 DOID:552 DOID:557 DOID:5723 DOID:574 DOID:576 DOID:5844 DOID:5854 DOID:5998 DOID:6000 DOID:631 DOID:633 DOID:655 DOID:6713 DOID:782 DOID:784 DOID:83 DOID:8398 DOID:8469 DOID:848 DOID:850 DOID:870 DOID:898 DOID:9240 DOID:9266 DOID:9286 DOID:9351 DOID:9352 DOID:9360 DOID:9408 DOID:9409 DOID:9415 DOID:9455 DOID:9521 DOID:9744 DOID:9808 DOID:9810 DOID:9870 DOID:988 DOID:9993	Golgi apparatus alpha-galactosidase activity azurophil granule lumen catalytic activity cytoplasm extracellular exosome extracellular region galactoside binding glycoside catabolic process glycosphingolipid catabolic process glycosylceramide catabolic process hydrolase activity lysosomal lumen lysosome negative regulation of nitric oxide biosynthetic process negative regulation of nitric-oxide synthase activity oligosaccharide metabolic process protein homodimerization activity signaling receptor binding	GO:0003824 GO:0004557 GO:0005102 GO:0005576 GO:0005737 GO:0005764 GO:0005794 GO:0009311 GO:0016139 GO:0016787 GO:0016936 GO:0035578 GO:0042803 GO:0043202 GO:0045019 GO:0046477 GO:0046479 GO:0051001 GO:0070062
Q4WNE4	Probable beta-galactosidase C	lacC	Aspergillus fumigatus Af293	330879	12	0				beta-galactosidase activity extracellular region polysaccharide catabolic process vacuole	GO:0000272 GO:0004565 GO:0005576 GO:0005773
A1DJ58	Probable beta-galactosidase E	lacE	Aspergillus fischeri NRRL 181	331117	12	0				beta-galactosidase activity extracellular region polysaccharide catabolic process vacuole	GO:0000272 GO:0004565 GO:0005576 GO:0005773
Q7F9K4	Beta-glucosidase 10	BGLU10	Oryza sativa Japonica Group (Japanese rice)	39947	3	0				beta-D-fucosidase activity beta-galactosidase activity beta-glucosidase activity carbohydrate metabolic process scopolin beta-glucosidase activity	GO:0004565 GO:0005975 GO:0008422 GO:0033907 GO:0102483
Q0J0N4	Beta-glucosidase 30	BGLU30	Oryza sativa Japonica Group (Japanese rice)	39947	5	0				beta-D-fucosidase activity beta-galactosidase activity beta-glucosidase activity carbohydrate metabolic process scopolin beta-glucosidase activity	GO:0004565 GO:0005975 GO:0008422 GO:0033907 GO:0102483
Q5ARP5	Probable alpha-galactosidase G	aglG	Aspergillus nidulans FGSC A4	227321	5	0				alpha-galactosidase activity extracellular region polysaccharide catabolic process	GO:0000272 GO:0004557 GO:0005576
Q54GE1	Beta-galactosidase 1	glb1	Dictyostelium discoideum	44689	8	0				beta-galactosidase activity carbohydrate metabolic process lysosome vacuole	GO:0004565 GO:0005764 GO:0005773 GO:0005975
P41945	Alpha-galactosidase 2	MEL2	Saccharomyces cerevisiae (brewer's yeast)	4932	9	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
Q2UT06	Probable alpha-galactosidase A	aglA	Aspergillus oryzae RIB40	510516	6	0				alpha-galactosidase activity carbohydrate binding cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139 GO:0030246
Q95LV1	Beta-galactosidase-1-like protein	GLB1L	Macaca fascicularis (crab-eating macaque)	9541	2	0				beta-galactosidase activity carbohydrate metabolic process extracellular region vacuole	GO:0004565 GO:0005576 GO:0005773 GO:0005975
B8MWJ5	Probable alpha-galactosidase A	aglA	Aspergillus flavus NRRL3357	332952	6	0				alpha-galactosidase activity carbohydrate binding cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139 GO:0030246
Q0CVH2	Probable alpha-galactosidase C	aglC	Aspergillus terreus NIH2624	341663	7	0				alpha-galactosidase activity extracellular region polysaccharide catabolic process	GO:0000272 GO:0004557 GO:0005576

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