GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen, GlyConnect, GlycoProtDB and The O-GlcNAc Database. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Source	Last Updated
GlyConnect	April 19, 2023
GlycoProtDB	October 1, 2021
GlyGen	October 30, 2024
The O-GlcNAc Database	August 9, 2024
UniProt	October 29, 2024

Displaying entries **1 - 25** of **199** in total

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UniProt ID	Protein Name ▲	Gene Symbol	Organism	Taxonomy ID	No. of Glycosylation Sites	No. of GlyTouCan IDs	GlyTouCan ID	Disease Ontology	Disease Ontology ID	Gene Ontology	Gene Ontology ID
Q66H12	Alpha-N-acetylgalactosaminidase	Naga	Rattus norvegicus (Norway rat)	10116	4	0				alpha-N-acetylgalactosaminidase activity alpha-galactosidase activity carbohydrate catabolic process cytoplasm glycolipid catabolic process glycoside catabolic process lysosome oligosaccharide metabolic process protein homodimerization activity	GO:0004557 GO:0005737 GO:0005764 GO:0008456 GO:0009311 GO:0016052 GO:0016139 GO:0019377 GO:0042803
Q90744	Alpha-N-acetylgalactosaminidase	NAGA	Gallus gallus (chicken)	9031	3	0				alpha-N-acetylgalactosaminidase activity alpha-galactosidase activity cytoplasm glycoside catabolic process lipid metabolic process lysosome oligosaccharide metabolic process	GO:0004557 GO:0005737 GO:0005764 GO:0006629 GO:0008456 GO:0009311 GO:0016139
P17050	Alpha-N-acetylgalactosaminidase	NAGA	Homo sapiens (human)	9606	5	94	G00155YT G00406II G01543ZX G02815KT G03005MJ G03275SD G03382KH G03842KQ G05724UK G05808PZ G06110VR G06356OH G06885ZB G07617FP G10486CT G11629QQ G12313PD G12849CJ G14389GM G14669DU G14889BN G15169WU G16828VN G17689DH G20210JR G20425TQ G20512LK G22310AV G22768VO G23863VK G23984SE G25637MV G29857RC G29880MM G31852PQ G33282QL G34617SM G36191CD G39188ZX G39595FH G41247ZX G44444MB G45209NR G45359RY G45546UR G48414YA G50045TK G50282JC G51640FO G53280MT G55220VL G55521GY G57789QC G59575FI G60723SV G61138BO G61334IA G61962FK G63889NK G64394MX G66129DI G71470CO G72291OX G72735IY G72797UR G74239ZQ G74724QE G75594YZ G77252PU G78059CC G78790NZ G79809MM G80966KZ G81263BG G81349OI G82348BZ G82350PP G82463GQ G83161QT G83460ZZ G84349RE G84452RH G86357DX G90093AU G90448RI G90575OW G90717TP G91413ZX G92050GC G92275SC G93180LE G93284HQ G97183VL G97720QM	Kanzaki disease Schindler disease type 1	DOID:0112318 DOID:0112319	alpha-N-acetylgalactosaminidase activity alpha-galactosidase activity carbohydrate catabolic process cytoplasm extracellular exosome glycolipid catabolic process glycoside catabolic process lysosome oligosaccharide metabolic process protein homodimerization activity	GO:0004557 GO:0005737 GO:0005764 GO:0008456 GO:0009311 GO:0016052 GO:0016139 GO:0019377 GO:0042803 GO:0070062
Q58DH9	Alpha-N-acetylgalactosaminidase	NAGA	Bos taurus (domestic cattle)	9913	5	0				alpha-N-acetylgalactosaminidase activity alpha-galactosidase activity carbohydrate catabolic process cytoplasm glycolipid catabolic process glycoside catabolic process lysosome oligosaccharide metabolic process	GO:0004557 GO:0005737 GO:0005764 GO:0008456 GO:0009311 GO:0016052 GO:0016139 GO:0019377
Q9QWR8	Alpha-N-acetylgalactosaminidase	Naga	Mus musculus (house mouse)	10090	3	3	G03238UC G62765YT G93180LE			alpha-N-acetylgalactosaminidase activity alpha-galactosidase activity carbohydrate catabolic process cytoplasm glycolipid catabolic process glycoside catabolic process lysosome oligosaccharide metabolic process protein homodimerization activity	GO:0004557 GO:0005737 GO:0005764 GO:0008456 GO:0009311 GO:0016052 GO:0016139 GO:0019377 GO:0042803
Q9UVD6	Alpha-galactosidase	MEL	Torulaspora delbrueckii	4950	7	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
Q09187	Alpha-galactosidase	MEL	Saccharomyces paradoxus	27291	9	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
Q03647	Alpha-galactosidase	MEL	Saccharomyces pastorianus CBS 1513	1073566	9	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
Q9P4V4	Alpha-galactosidase	MEL	Zygotorulaspora mrakii	42260	9	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
Q21801	Alpha-galactosidase	gana-1	Caenorhabditis elegans	6239	3	0				alpha-galactosidase activity cytoplasm glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005737 GO:0009311 GO:0016139
Q53Y83	Alpha-galactosidase	GLA	Homo sapiens (human)	9606	2	0				alpha-galactosidase activity galactoside binding glycoside catabolic process lipid metabolic process lysosome oligosaccharide metabolic process	GO:0004557 GO:0005764 GO:0006629 GO:0009311 GO:0016139 GO:0016936
Q99172	Alpha-galactosidase	MEL	Lachancea cidri	29831	9	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
Q11129	Alpha-galactosidase	MEL	Saccharomyces mikatae	114525	9	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process oligosaccharide metabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0009311 GO:0016139
Q8BGZ6	Alpha-galactosidase	Gla	Mus musculus (house mouse)	10090	2	0				Golgi apparatus alpha-galactosidase activity extracellular region galactoside binding glycosphingolipid catabolic process lysosome oligosaccharide metabolic process protein homodimerization activity signaling receptor binding	GO:0004557 GO:0005102 GO:0005576 GO:0005764 GO:0005794 GO:0009311 GO:0016936 GO:0042803 GO:0046479
P04824	Alpha-galactosidase 1	MEL1	Saccharomyces cerevisiae (brewer's yeast)	4932	9	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process melibiose catabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0005995 GO:0016139
Q9FT97	Alpha-galactosidase 1	AGAL1	Arabidopsis thaliana (thale cress)	3702	2	0				alpha-galactosidase activity apoplast carbohydrate metabolic process cell wall organization plant-type cell wall secretory vesicle	GO:0004557 GO:0005975 GO:0009505 GO:0048046 GO:0071555 GO:0099503
P41945	Alpha-galactosidase 2	MEL2	Saccharomyces cerevisiae (brewer's yeast)	4932	9	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process melibiose catabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0005995 GO:0016139
Q92457	Alpha-galactosidase 2	agl2	Trichoderma reesei	51453	9	0				alpha-galactosidase activity carbohydrate catabolic process extracellular region	GO:0004557 GO:0005576 GO:0016052
Q8RX86	Alpha-galactosidase 2	AGAL2	Arabidopsis thaliana (thale cress)	3702	3	0				alpha-galactosidase activity apoplast cell wall organization galactomannan catabolic process leaf morphogenesis plant-type cell wall positive regulation of flower development response to fungus secretory vesicle	GO:0004557 GO:0009505 GO:0009620 GO:0009911 GO:0009965 GO:0048046 GO:0051682 GO:0071555 GO:0099503
Q8VXZ7	Alpha-galactosidase 3	AGAL3	Arabidopsis thaliana (thale cress)	3702	5	0				alpha-galactosidase activity apoplast carbohydrate metabolic process cell wall organization plant-type vacuole secretory vesicle vacuole	GO:0000325 GO:0004557 GO:0005773 GO:0005975 GO:0048046 GO:0071555 GO:0099503
Q92451	Alpha-galactosidase 3	agl3	Trichoderma reesei	51453	7	0				alpha-galactosidase activity carbohydrate metabolic process extracellular region	GO:0004557 GO:0005576 GO:0005975
P41946	Alpha-galactosidase 5	MEL5	Saccharomyces cerevisiae (brewer's yeast)	4932	8	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process melibiose catabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0005995 GO:0016139
P41947	Alpha-galactosidase 6	MEL6	Saccharomyces cerevisiae (brewer's yeast)	4932	8	0				alpha-galactosidase activity cytoplasm extracellular region glycoside catabolic process melibiose catabolic process	GO:0004557 GO:0005576 GO:0005737 GO:0005995 GO:0016139
P51569	Alpha-galactosidase A	Gla Ags	Mus musculus (house mouse)	10090	3	0				Golgi apparatus alpha-galactosidase activity aorta development catalytic activity cytoplasm extracellular region extracellular space galactoside binding glycoside catabolic process glycosylceramide catabolic process hydrolase activity lysosome negative regulation of nitric oxide biosynthetic process negative regulation of nitric-oxide synthase activity oligosaccharide metabolic process protein homodimerization activity signaling receptor binding	GO:0003824 GO:0004557 GO:0005102 GO:0005576 GO:0005615 GO:0005737 GO:0005764 GO:0005794 GO:0009311 GO:0016139 GO:0016787 GO:0016936 GO:0035904 GO:0042803 GO:0045019 GO:0046477 GO:0051001
P06280	Alpha-galactosidase A	GLA	Homo sapiens (human)	9606	3	43	G00406II G00912UN G01937VC G05724UK G06110VR G06247RL G11870QZ G12313PD G14669DU G15169WU G23294PN G23719VF G27058EU G28681TP G29184RN G31852PQ G34989PA G37412TK G39188ZX G41247ZX G43669FQ G45395BF G46503DX G47012YE G47644PP G48414YA G50282JC G62765YT G62894KT G70101JE G70232NH G72291OX G74724QE G75983OB G76417NN G80920RR G82463GQ G83460ZZ G90382BL G90575OW G92275SC G95995BI G96091TT	Fabry disease	DOID:14499	Golgi apparatus alpha-galactosidase activity azurophil granule lumen catalytic activity cytoplasm extracellular exosome extracellular region galactoside binding glycoside catabolic process glycosphingolipid catabolic process glycosylceramide catabolic process hydrolase activity lysosomal lumen lysosome negative regulation of nitric oxide biosynthetic process negative regulation of nitric-oxide synthase activity oligosaccharide metabolic process protein homodimerization activity signaling receptor binding	GO:0003824 GO:0004557 GO:0005102 GO:0005576 GO:0005737 GO:0005764 GO:0005794 GO:0009311 GO:0016139 GO:0016787 GO:0016936 GO:0035578 GO:0042803 GO:0043202 GO:0045019 GO:0046477 GO:0046479 GO:0051001 GO:0070062

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