GlyCosmos Portal

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database	Last Updated
GlyConnect	February 2, 2022
GlycoProtDB	October 1, 2021
GlyGen	February 2, 2022
Human Protein Atlas	September 5, 2019 (Protein Atlas version 19)
MCAW-DB	July 10, 2019
Reactome	October 28, 2022 (Version 82)
UniProt	September 8, 2022

Protein Name	UniProt ID	Gene Symbol	Alias Symbols	Species	No. of Glycosylation Sites	No. of GlyTouCan IDs	Disease Name	Disease Aliases ▲
V-type proton ATPase 116 kDa subunit a 2	Q9Y487	ATP6V0A2		Homo sapiens	2	2	ATP6VOA2-CDG	ATP6VOA2 defect (cutis laxa type II) Cutis laxa, autosomal recessive, type IIA (ARCL2A) Debre-Type cutis laxa V-ATPase a2 subunit defect
Lysosomal acid lipase/cholesteryl ester hydrolase	P38571	LIPA		Homo sapiens	6	11	Wolman disease	Acid lipase deficiency Lysosomal acid lipase deficiency
Carbohydrate sulfotransferase 14	Q8NCH0	CHST14	D4ST1	Homo sapiens	2	0	Ehlers-Danlos syndrome, musculocontractural type	Adducted thumb and clubfoot syndrome
Alpha-galactosidase A	P06280	GLA		Homo sapiens	3	18	Fabry disease	Alpha-galactosidase A deficiency
Lysosomal alpha-mannosidase	O00754	MAN2B1	LAMAN MANB	Homo sapiens	11	16	Alpha-mannosidosis	Alpha-mannosidase B deficiency
Lactosylceramide alpha-2,3-sialyltransferase	Q9UNP4	ST3GAL5	SIAT9	Homo sapiens	3	0	ST3GAL5-CDG	Amish infantile epilepsy syndrome Epilepsy syndrome, infantile-onset symptomatic GM3 Synthase deficiency
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	O00469	PLOD2		Homo sapiens	7	9	Bruck syndrome 2	BRKS2 Osteogenesis imperfecta with congenital joint contractures
Beta-mannosidase	O00462	MANBA	MANB1	Homo sapiens	8	2	Beta-mannosidosis	Beta-mannosidase deficiency
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3	O60568	PLOD3		Homo sapiens	2	10	Lysyl hydroxylase 3 deficiency	Bone fragility with contractures, arterial rupture, and deafness LH3 deficiency
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Q10469	MGAT2		Homo sapiens	2	1	MGAT2-CDG	CDG-IIa Congenital disorder of glycosylation, type IIa