GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen and GlyConnect. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

Database Last Updated
GlyConnect February 2, 2022
GlycoProtDB October 1, 2021
GlyGen February 2, 2022
Human Protein Atlas September 5, 2019 (Protein Atlas version 19)
MCAW-DB July 10, 2019
Reactome February 8, 2021 (Version 79)
UniProt July 20, 2022
Protein Name UniProt ID Gene Symbol Species No. of Glycosylation Sites No. of GlyTouCan IDs Disease Name Disease Aliases ▲
ATP6V0A2
Homo sapiens
2
2
ATP6VOA2-CDG
  • ATP6VOA2 defect (cutis laxa type II)
  • Cutis laxa, autosomal recessive, type IIA (ARCL2A)
  • Debre-Type cutis laxa
  • V-ATPase a2 subunit defect
LIPA
Homo sapiens
6
11
Wolman disease
  • Acid lipase deficiency
  • Lysosomal acid lipase deficiency
HEXA
Homo sapiens
3
7
Tay-Sachs disease, infantile form
  • Acute infantile
CHST14
Homo sapiens
2
0
Ehlers-Danlos syndrome, musculocontractural type
  • Adducted thumb and clubfoot syndrome
GLA
Homo sapiens
3
18
Fabry disease
  • Alpha-galactosidase A deficiency
ST3GAL5
Homo sapiens
3
0
ST3GAL5-CDG
  • Amish infantile epilepsy syndrome
  • Epilepsy syndrome, infantile-onset symptomatic
  • GM3 Synthase deficiency
PLOD2
Homo sapiens
7
9
Bruck syndrome 2
  • BRKS2
  • Osteogenesis imperfecta with congenital joint contractures
MANBA
Homo sapiens
8
2
Beta-mannosidosis
  • Beta-mannosidase deficiency
PLOD3
Homo sapiens
2
10
Lysyl hydroxylase 3 deficiency
  • Bone fragility with contractures, arterial rupture, and deafness
  • LH3 deficiency
MGAT2
Homo sapiens
2
1
MGAT2-CDG
  • CDG-IIa
  • Congenital disorder of glycosylation, type IIa
Displaying entries 1 - 10 of 65960 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01