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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor
Summary
- UniProt ID
- Q28J96
- Gene Symbol
-
- fgfr1
- X1FGFR
- XFGFR-1
- bfgfr
- cd331
- cek
- fgfbr
- fgfr-1
- fgfr1-a
- fgfr1-b
- flg
- flt-2
- flt2
- hbgfr
- kal2
- n-sam
- ogd
- xfgfr1
- Organism
- Xenopus tropicalis (tropical clawed frog)
External Links
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Nucleus
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| plasma membrane |
| cytoplasmic vesicle |
| receptor complex |
| cytosol |
| GO Term |
|---|
| fibroblast growth factor receptor activity |
| fibroblast growth factor binding |
| ATP binding |
Sequence
MFSGRSLLLWGVLLGAALSVARPPSTLPDQVAPKTKTDVEPYSARPGDRITLQCRLREDVQSINWAKNEMQLSETNRTRITGEEIQISNAGPEDNGVYTCVTNGPSGTYTVLFSVNVSDALPSAEDDDDDDDNSSSEEKASENSKPNRPFWSHPEKMEKKLHAVPAAKTVKFRCPANGTPQPNLRWLKNGKEFRQDQRIGGYKVRSQTWSLIMDSVVPSDKGNYTCIVENKYGTLNHTYQLDVVERSPHRPILQAGLPANTSVIVGSTAEFFCKVYSDPQPHIQWLRHIEINGSRVASDGFPYVEILKTAGVNTSDKDMEVLHLRNVTFEDAGQYTCLAANSIGISHHSAWLTVLEVEDDKPAPLASPLQLEIIIYCTGAAFVSAMVITIIIFKMKHPSKKSDFNSQLAVHKLAKSIPLRRQVTVSGDSNSSMHSGVILVRPSRLSSSGTPMLSGVSEYELPEDPRWEVARDRLILGKPLGEGCFGQVVMAEAIGLDKEKPNKVTKVAVKMLKSDASEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYCYNPTCAPDQLLSFKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPMEELFKLLKEGHRMDKPTTCTNELYMMMKDCWHAMPSQRPTFNQLVEDLDRILALSSNQEYLDLSMPVNQYSPCFPDTRSSTCSSGEDSVFSHDPLPDEPCLPKYSNGGLKKR
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 76 | N-linked (GlcNAc...) asparagine |
|
||
| 116 | N-linked (GlcNAc...) asparagine |
|
||
| 223 | N-linked (GlcNAc...) asparagine |
|
||
| 236 | N-linked (GlcNAc...) asparagine |
|
||
| 260 | N-linked (GlcNAc...) asparagine |
|
||
| 292 | N-linked (GlcNAc...) asparagine |
|
||
| 313 | N-linked (GlcNAc...) asparagine |
|
||
| 326 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream signaling of activated FGFR1 | Xenopus tropicalis |
| FGFR1b ligand binding and activation | Xenopus tropicalis |
| FGFR1c and Klotho ligand binding and activation | Xenopus tropicalis |
| FGFR1c ligand binding and activation | Xenopus tropicalis |
| FRS-mediated FGFR1 signaling | Xenopus tropicalis |
| Negative regulation of FGFR1 signaling | Xenopus tropicalis |
| PI-3K cascade:FGFR1 | Xenopus tropicalis |
| PI3K Cascade | Xenopus tropicalis |
| PI3K/AKT Signaling | Xenopus tropicalis |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Xenopus tropicalis |
