GlyCosmos Portal

Source	Last Updated
MCAW	July 10, 2019
UniLectin	June 14, 2023
UniProt	June 6, 2024
Lectin Frontier DataBase (LfDB)	April 6, 2018
CarboGrove	June 14, 2023

Displaying entries **226 - 250** of **5271** in total

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Lectin Name	UniProt ID	Monosaccharide Specificities	Organism	Taxonomy ID ▼	Gene Ontology	Gene Ontology ID
C-type lectin domain family 12 member B	Q2HXU8		Homo sapiens (human)	9606	carbohydrate binding external side of plasma membrane melanocyte proliferation natural killer cell inhibitory signaling pathway negative regulation of natural killer cell mediated cytotoxicity negative regulation of receptor signaling pathway via STAT negative regulation of signaling receptor activity protein phosphatase binding protein-containing complex signaling receptor inhibitor activity	GO:0002769 GO:0009897 GO:0019903 GO:0030246 GO:0030547 GO:0032991 GO:0045953 GO:0097325 GO:1904893 GO:2000272
Pleiotrophin	P21246		Homo sapiens (human)	9606	Schaffer collateral - CA1 synapse bone mineralization carbohydrate binding chondroitin sulfate binding decidualization dendrite arborization dendrite regeneration endoplasmic reticulum estrous cycle extracellular region extracellular space growth factor activity heparin binding integrin binding integrin-mediated signaling pathway learning leukocyte chemotaxis involved in inflammatory response memory molecular function activator activity negative regulation of long-term synaptic potentiation negative regulation of neuroblast proliferation nervous system development oogenesis ossification involved in bone remodeling plasma membrane positive regulation of axon regeneration positive regulation of bone mineralization positive regulation of cell division positive regulation of cell population proliferation positive regulation of dendrite development positive regulation of hepatocyte proliferation positive regulation of leukocyte chemotaxis positive regulation of neuron projection development positive regulation of oligodendrocyte differentiation positive regulation of ossification positive regulation of stem cell differentiation protein kinase binding protein phosphatase inhibitor activity protein-containing complex receptor clustering regulation of endothelial cell migration regulation of hemopoiesis regulation of myelination regulation of stem cell population maintenance regulation of synaptic plasticity response to auditory stimulus tissue regeneration transmembrane receptor protein tyrosine phosphatase signaling pathway	GO:0002232 GO:0002690 GO:0004864 GO:0005178 GO:0005576 GO:0005615 GO:0005783 GO:0005886 GO:0007185 GO:0007229 GO:0007399 GO:0007406 GO:0007612 GO:0007613 GO:0008083 GO:0008201 GO:0008284 GO:0010594 GO:0010976 GO:0010996 GO:0019901 GO:0030246 GO:0030282 GO:0030501 GO:0031104 GO:0031641 GO:0032991 GO:0035374 GO:0042246 GO:0043113 GO:0043932 GO:0044849 GO:0045778 GO:0046697 GO:0048167 GO:0048477 GO:0048680 GO:0048714 GO:0051781 GO:0098685 GO:0140059 GO:0140677 GO:1900006 GO:1900272 GO:1903706 GO:2000036 GO:2000347 GO:2000738
Trefoil factor 1	P04155		Homo sapiens (human)	9606	carbohydrate metabolic process cell differentiation cell population proliferation extracellular region extracellular space growth factor activity maintenance of gastrointestinal epithelium negative regulation of cell population proliferation response to immobilization stress response to iron ion response to peptide hormone	GO:0005576 GO:0005615 GO:0005975 GO:0008083 GO:0008283 GO:0008285 GO:0010039 GO:0030154 GO:0030277 GO:0035902 GO:0043434
C-type lectin domain family 4 member F	Q8N1N0		Homo sapiens (human)	9606	carbohydrate binding endocytosis external side of plasma membrane	GO:0006897 GO:0009897 GO:0030246
C-type lectin domain family 4 member A	Q9UMR7		Homo sapiens (human)	9606	CD8-positive, alpha-beta T cell activation adaptive immune response antifungal innate immune response antigen processing and presentation of exogenous peptide antigen via MHC class I calcium ion binding carbohydrate binding cell adhesion cell surface receptor signaling pathway external side of plasma membrane mannose binding negative regulation of cytokine production negative regulation of tumor necrosis factor production plasma membrane plasmacytoid dendritic cell antigen processing and presentation transmembrane signaling receptor activity	GO:0001818 GO:0002250 GO:0002470 GO:0004888 GO:0005509 GO:0005537 GO:0005886 GO:0007155 GO:0007166 GO:0009897 GO:0030246 GO:0032720 GO:0036037 GO:0042590 GO:0061760
C-type lectin domain family 19 member A	Q6UXS0		Homo sapiens (human)	9606	carbohydrate binding extracellular region signaling receptor activity	GO:0005576 GO:0030246 GO:0038023
C-type lectin domain family 2 member L	P0C7M8		Homo sapiens (human)	9606	carbohydrate binding membrane	GO:0016020 GO:0030246
Sialic acid-binding Ig-like lectin 10	Q96LC7		Homo sapiens (human)	9606	SH2 domain binding adaptive immune response carbohydrate binding cell adhesion extracellular region innate immune response negative regulation of inflammatory response to wounding phosphatase binding plasma membrane sialic acid binding	GO:0002250 GO:0005576 GO:0005886 GO:0007155 GO:0019902 GO:0030246 GO:0033691 GO:0042169 GO:0045087 GO:0106015
Fucose mutarotase	A2VDF0		Homo sapiens (human)	9606	L-fucose mutarotase activity cytosol fucose binding fucose metabolic process fucosylation racemase and epimerase activity, acting on carbohydrates and derivatives	GO:0005829 GO:0006004 GO:0016857 GO:0036065 GO:0036373 GO:0042806
E-selectin	P16581		Homo sapiens (human)	9606	actin filament-based process activation of phospholipase C activity calcium-mediated signaling caveola clathrin-coated pit cortical cytoskeleton external side of plasma membrane extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules inflammatory response leukocyte cell-cell adhesion leukocyte migration involved in inflammatory response leukocyte tethering or rolling membrane raft metal ion binding oligosaccharide binding perinuclear region of cytoplasm phospholipase binding plasma membrane positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of receptor internalization regulation of inflammatory response response to cytokine response to interleukin-1 response to lipopolysaccharide response to tumor necrosis factor sialic acid binding transmembrane signaling receptor activity	GO:0002092 GO:0002523 GO:0002687 GO:0004888 GO:0005615 GO:0005886 GO:0005901 GO:0005905 GO:0006954 GO:0007157 GO:0007159 GO:0007202 GO:0009897 GO:0019722 GO:0030029 GO:0030863 GO:0032496 GO:0033691 GO:0034097 GO:0034612 GO:0043274 GO:0045121 GO:0046872 GO:0048471 GO:0050727 GO:0050901 GO:0070492 GO:0070555 GO:1903238
Collectin-11	Q9BWP8		Homo sapiens (human)	9606	DNA binding antimicrobial humoral response calcium ion binding calcium-dependent carbohydrate binding cell surface pattern recognition receptor signaling pathway collagen trimer complement activation, lectin pathway complement activation developmental process execution phase of apoptosis external side of plasma membrane extracellular region extracellular space fucose binding identical protein binding mannose binding oligosaccharide binding positive regulation of opsonization proteolysis serine-type endopeptidase complex	GO:0001867 GO:0002752 GO:0003677 GO:0005509 GO:0005537 GO:0005576 GO:0005581 GO:0005615 GO:0006508 GO:0006956 GO:0009897 GO:0019730 GO:0032502 GO:0042802 GO:0042806 GO:0070492 GO:0097194 GO:0120153 GO:1903028 GO:1905370
Hexokinase-4	P35557		Homo sapiens (human)	9606	ATP binding NADP metabolic process calcium ion import canonical glycolysis carbohydrate phosphorylation cellular response to insulin stimulus cellular response to leptin stimulus cytosol fructokinase activity glucokinase activity glucose 6-phosphate metabolic process glucose binding glucose catabolic process glucose homeostasis glucose metabolic process glucose sensor activity glycolytic process intracellular glucose homeostasis mannokinase activity mitochondrion negative regulation of gluconeogenesis nucleoplasm positive regulation of glycogen biosynthetic process positive regulation of insulin secretion regulation of glycolytic process regulation of insulin secretion regulation of potassium ion transport response to glucose	GO:0001678 GO:0004340 GO:0005524 GO:0005536 GO:0005654 GO:0005739 GO:0005829 GO:0006006 GO:0006007 GO:0006096 GO:0006110 GO:0006739 GO:0008865 GO:0009749 GO:0019158 GO:0032024 GO:0032869 GO:0042593 GO:0043266 GO:0044320 GO:0045721 GO:0045725 GO:0046835 GO:0050796 GO:0051156 GO:0061621 GO:0070509 GO:0141089
Sorbitol dehydrogenase	Q00796		Homo sapiens (human)	9606	(R,R)-butanediol dehydrogenase activity D-sorbitol dehydrogenase (acceptor) activity D-xylulose reductase activity L-iditol 2-dehydrogenase activity L-xylitol catabolic process L-xylitol metabolic process NAD binding carbohydrate binding cytosol extracellular exosome extracellular space flagellated sperm motility fructose biosynthetic process glucose metabolic process glucuronate catabolic process to xylulose 5-phosphate identical protein binding membrane mitochondrial membrane motile cilium ribitol 2-dehydrogenase activity sorbitol catabolic process zinc ion binding	GO:0000721 GO:0003939 GO:0005615 GO:0005829 GO:0006006 GO:0006062 GO:0008270 GO:0016020 GO:0019640 GO:0030246 GO:0030317 GO:0031514 GO:0031966 GO:0042802 GO:0046370 GO:0046526 GO:0047833 GO:0050255 GO:0051160 GO:0051164 GO:0051287 GO:0070062
Galectin-3 Aliases: Gal3 Galectin-3 (Human)	P17931	Gal	Homo sapiens (human)	9606	IgE binding RNA binding RNA splicing carbohydrate binding cell surface chemoattractant activity collagen-containing extracellular matrix cytoplasm cytosol disaccharide binding eosinophil chemotaxis epithelial cell differentiation extracellular exosome extracellular region extracellular space ficolin-1-rich granule membrane immunological synapse innate immune response laminin binding mRNA processing macrophage chemotaxis membrane mitochondrial inner membrane molecular condensate scaffold activity monocyte chemotaxis mononuclear cell migration negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell negative regulation of T cell receptor signaling pathway negative regulation of endocytosis negative regulation of extrinsic apoptotic signaling pathway negative regulation of immunological synapse formation negative regulation of protein tyrosine phosphatase activity neutrophil chemotaxis nucleoplasm nucleus plasma membrane positive chemotaxis positive regulation of calcium ion import positive regulation of mononuclear cell migration positive regulation of protein localization to plasma membrane positive regulation of protein-containing complex assembly protein phosphatase binding protein phosphatase inhibitor activity regulation of T cell apoptotic process regulation of T cell proliferation regulation of extrinsic apoptotic signaling pathway via death domain receptors secretory granule membrane spliceosomal complex	GO:0001772 GO:0002548 GO:0003723 GO:0004864 GO:0005576 GO:0005615 GO:0005634 GO:0005654 GO:0005681 GO:0005737 GO:0005743 GO:0005829 GO:0005886 GO:0006397 GO:0008380 GO:0009986 GO:0016020 GO:0019863 GO:0019903 GO:0030246 GO:0030593 GO:0030667 GO:0030855 GO:0031334 GO:0042056 GO:0042129 GO:0043236 GO:0045087 GO:0045806 GO:0048030 GO:0048245 GO:0048246 GO:0050860 GO:0050918 GO:0062023 GO:0070062 GO:0070232 GO:0071674 GO:0071677 GO:0090280 GO:0101003 GO:0140693 GO:1902041 GO:1903078 GO:1903614 GO:2000521 GO:2001189 GO:2001237
Prolyl 4-hydroxylase subunit alpha-3	Q7Z4N8		Homo sapiens (human)	9606	L-ascorbic acid binding endoplasmic reticulum lumen endoplasmic reticulum iron ion binding procollagen-proline 4-dioxygenase activity	GO:0004656 GO:0005506 GO:0005783 GO:0005788 GO:0031418
Galectin-7 Aliases: Galectin-7 (Human)	P47929	Gal	Homo sapiens (human)	9606	apoptotic process carbohydrate binding cytoplasm extracellular exosome extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules nucleus	GO:0005615 GO:0005634 GO:0005737 GO:0006915 GO:0007157 GO:0030246 GO:0070062
Polypeptide N-acetylgalactosaminyltransferase 17	Q6IS24		Homo sapiens (human)	9606	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0030246 GO:0046872
Polypeptide N-acetylgalactosaminyltransferase 2	Q10471		Homo sapiens (human)	9606	Golgi apparatus Golgi cisterna membrane Golgi membrane Golgi stack O-glycan processing carbohydrate binding endoplasmic reticulum membrane extracellular region manganese ion binding membrane perinuclear region of cytoplasm polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation via serine protein O-linked glycosylation via threonine protein O-linked glycosylation protein maturation	GO:0000139 GO:0004653 GO:0005576 GO:0005789 GO:0005794 GO:0005795 GO:0006493 GO:0016020 GO:0016266 GO:0018242 GO:0018243 GO:0030145 GO:0030246 GO:0032580 GO:0048471 GO:0051604
Protein FAM3B	P58499		Homo sapiens (human)	9606	apoptotic process carbohydrate binding cytokine activity extracellular exosome extracellular region extracellular space insulin secretion	GO:0005125 GO:0005576 GO:0005615 GO:0006915 GO:0030073 GO:0030246 GO:0070062
C-type lectin domain family 4 member E	Q9ULY5		Homo sapiens (human)	9606	Fc-gamma receptor signaling pathway T cell differentiation involved in immune response antifungal innate immune response calcium ion binding carbohydrate binding cell projection defense response to bacterium external side of plasma membrane glycolipid binding innate immune response membrane pattern recognition receptor activity pattern recognition receptor signaling pathway phagocytic cup phagocytic vesicle membrane plasma membrane positive regulation of cytokine production	GO:0001819 GO:0001891 GO:0002221 GO:0002292 GO:0005509 GO:0005886 GO:0009897 GO:0016020 GO:0030246 GO:0030670 GO:0038094 GO:0038187 GO:0042742 GO:0042995 GO:0045087 GO:0051861 GO:0061760
Prolyl 3-hydroxylase 1	Q32P28		Homo sapiens (human)	9606	L-ascorbic acid binding bone development chaperone-mediated protein folding collagen metabolic process cytoplasm endoplasmic reticulum lumen endoplasmic reticulum extracellular exosome iron ion binding membrane negative regulation of cell population proliferation negative regulation of post-translational protein modification nucleus positive regulation of neuron projection development procollagen-proline 3-dioxygenase activity protein folding protein hydroxylation protein stabilization protein-containing complex regulation of protein secretion	GO:0005506 GO:0005634 GO:0005737 GO:0005783 GO:0005788 GO:0006457 GO:0008285 GO:0010976 GO:0016020 GO:0018126 GO:0019797 GO:0031418 GO:0032963 GO:0032991 GO:0050708 GO:0050821 GO:0060348 GO:0061077 GO:0070062 GO:1901874
Glucose-6-phosphate isomerase	P06744		Homo sapiens (human)	9606	carbohydrate derivative binding carbohydrate metabolic process ciliary membrane cytokine activity cytosol erythrocyte homeostasis extracellular exosome extracellular region ficolin-1-rich granule lumen gluconeogenesis glucose 6-phosphate metabolic process glucose homeostasis glucose-6-phosphate isomerase activity glycolytic process growth factor activity hemostasis humoral immune response in utero embryonic development learning or memory membrane mesoderm formation monosaccharide binding negative regulation of neuron apoptotic process positive regulation of endothelial cell migration positive regulation of immunoglobulin production response to cadmium ion response to estradiol response to immobilization stress response to muscle stretch response to progesterone response to testosterone secretory granule lumen ubiquitin protein ligase binding	GO:0001701 GO:0001707 GO:0002639 GO:0004347 GO:0005125 GO:0005576 GO:0005829 GO:0005975 GO:0006094 GO:0006096 GO:0006959 GO:0007599 GO:0007611 GO:0008083 GO:0010595 GO:0016020 GO:0031625 GO:0032355 GO:0032570 GO:0033574 GO:0034101 GO:0034774 GO:0035902 GO:0035994 GO:0042593 GO:0043524 GO:0046686 GO:0048029 GO:0051156 GO:0060170 GO:0070062 GO:0097367 GO:1904813
Bone marrow proteoglycan	P13727		Homo sapiens (human)	9606	carbohydrate binding collagen-containing extracellular matrix defense response to bacterium defense response to nematode extracellular exosome extracellular matrix structural constituent conferring compression resistance extracellular region ficolin-1-rich granule lumen heparin binding immune response negative regulation of interleukin-10 production negative regulation of macrophage cytokine production positive regulation of interleukin-4 production transport vesicle	GO:0002215 GO:0005576 GO:0006955 GO:0008201 GO:0010936 GO:0030021 GO:0030133 GO:0030246 GO:0032693 GO:0032753 GO:0042742 GO:0062023 GO:0070062 GO:1904813
Complement C4-B	P0C0L5		Homo sapiens (human)	9606	axon blood microparticle carbohydrate binding complement activation, classical pathway complement activation complement binding dendrite detection of molecule of bacterial origin endopeptidase inhibitor activity extracellular exosome extracellular region extracellular space inflammatory response innate immune response opsonization plasma membrane positive regulation of apoptotic cell clearance symbiont cell surface synapse	GO:0001848 GO:0004866 GO:0005576 GO:0005615 GO:0005886 GO:0006954 GO:0006956 GO:0006958 GO:0008228 GO:0030246 GO:0030424 GO:0030425 GO:0032490 GO:0045087 GO:0045202 GO:0070062 GO:0072562 GO:0106139 GO:2000427
NKG2-C type II integral membrane protein	P26717		Homo sapiens (human)	9606	MHC class I protein complex binding activating MHC class Ib receptor activity adaptive immune response carbohydrate binding cellular defense response external side of plasma membrane natural killer cell mediated immunity plasma membrane positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity protein antigen binding receptor complex regulation of natural killer cell activation signal transduction stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0002223 GO:0002228 GO:0002250 GO:0004888 GO:0005886 GO:0006968 GO:0007165 GO:0009897 GO:0023024 GO:0030246 GO:0032814 GO:0043235 GO:0043323 GO:0045954 GO:0062081 GO:1990405

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