GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_001440	Endo-1,4-beta-xylanase Z	P10478	Acetivibrio thermocellus ATCC 27405	203119	carbohydrate binding endo-1,4-beta-xylanase activity xylan catabolic process xylan endo-1,3-beta-xylosidase activity	GO:0030246 GO:0031176 GO:0033905 GO:0045493
GL_000820	NKG2-C type II integral membrane protein	P26717	Homo sapiens	9606	MHC class I protein complex binding activating MHC class Ib receptor activity adaptive immune response carbohydrate binding cellular defense response external side of plasma membrane natural killer cell mediated immunity plasma membrane positive regulation of natural killer cell degranulation positive regulation of natural killer cell mediated cytotoxicity protein antigen binding receptor complex regulation of natural killer cell activation signal transduction stimulatory C-type lectin receptor signaling pathway transmembrane signaling receptor activity	GO:0002223 GO:0002228 GO:0002250 GO:0004888 GO:0005886 GO:0006968 GO:0007165 GO:0009897 GO:0023024 GO:0030246 GO:0032814 GO:0043235 GO:0043323 GO:0045954 GO:0062081 GO:1990405
GL_001661	Immune-associated nucleotide-binding protein 10	O81025	Arabidopsis thaliana	3702	GTP binding carbohydrate binding	GO:0005525 GO:0030246
GL_001829	Sclerostin	Q9BQB4	Homo sapiens	9606	BMP binding BMP signaling pathway DNA-binding transcription factor binding Golgi apparatus canonical Wnt signaling pathway carbohydrate binding cellular response to parathyroid hormone stimulus extracellular region extracellular space heparin binding localization molecular function inhibitor activity negative regulation of BMP signaling pathway negative regulation of Wnt signaling pathway negative regulation of canonical Wnt signaling pathway negative regulation of ossification negative regulation of protein-containing complex assembly ossification positive regulation of DNA-templated transcription protein-containing complex response to mechanical stimulus	GO:0001503 GO:0005576 GO:0005615 GO:0005794 GO:0008201 GO:0009612 GO:0030178 GO:0030246 GO:0030279 GO:0030509 GO:0030514 GO:0031333 GO:0032991 GO:0036122 GO:0045893 GO:0051179 GO:0060070 GO:0071374 GO:0090090 GO:0140297 GO:0140678
GL_000498	Galectin-3	P47953	Cricetulus longicaudatus	10030	IgE binding RNA splicing carbohydrate binding cell differentiation cytoplasm extracellular region innate immune response mRNA processing spliceosomal complex	GO:0005576 GO:0005681 GO:0005737 GO:0006397 GO:0008380 GO:0019863 GO:0030154 GO:0030246 GO:0045087
GL_001528	Glucans biosynthesis protein D	B5R535	Salmonella enterica subsp. enterica serovar Enteritidis str. P125109	550537	carbohydrate binding catalytic activity glucan biosynthetic process periplasmic space	GO:0003824 GO:0009250 GO:0030246 GO:0042597
GL_001892	Zona pellucida sperm-binding protein 3	P10761	Mus musculus	10090	acrosin binding binding of sperm to zona pellucida blastocyst formation carbohydrate binding collagen-containing extracellular matrix egg coat egg coat formation extracellular matrix extracellular space humoral immune response mediated by circulating immunoglobulin identical protein binding negative regulation of DNA-templated transcription negative regulation of binding of sperm to zona pellucida oocyte development plasma membrane positive regulation of DNA-templated transcription positive regulation of T cell proliferation positive regulation of acrosomal vesicle exocytosis positive regulation of acrosome reaction positive regulation of antral ovarian follicle growth positive regulation of humoral immune response positive regulation of inflammatory response positive regulation of interleukin-4 production positive regulation of leukocyte migration positive regulation of ovarian follicle development positive regulation of type II interferon production positive regulation of type IV hypersensitivity receptor ligand activity regulation of signaling receptor activity structural constituent of egg coat	GO:0001809 GO:0001825 GO:0002455 GO:0002687 GO:0002922 GO:0005615 GO:0005886 GO:0007339 GO:0010469 GO:0030246 GO:0031012 GO:0032190 GO:0032729 GO:0032753 GO:0035803 GO:0035804 GO:0035805 GO:0042102 GO:0042802 GO:0045892 GO:0045893 GO:0048018 GO:0048599 GO:0050729 GO:0062023 GO:2000344 GO:2000360 GO:2000368 GO:2000386 GO:2000388
GL_001372	Bifunctional protein GAL10	P09609	Kluyveromyces lactis NRRL Y-1140	284590	UDP-glucose 4-epimerase activity aldose 1-epimerase activity carbohydrate binding galactose metabolic process	GO:0003978 GO:0004034 GO:0006012 GO:0030246
GL_001734	Oligosaccharide 4-alpha-D-glucosyltransferase	B3PEE6	Cellvibrio japonicus Ueda107	498211	carbohydrate binding carbohydrate metabolic process hydrolase activity, hydrolyzing O-glycosyl compounds oligosaccharide 4-alpha-D-glucosyltransferase activity	GO:0004553 GO:0005975 GO:0030246 GO:0033825
GL_000305	Cell surface hyaluronidase	Q5FWI3	Mus musculus	10090	angiogenesis calcium ion binding carbohydrate binding cytosol hyaluronan catabolic process hyalurononglucosaminidase activity intracellular membrane-bounded organelle nucleolus plasma membrane regulation of sprouting angiogenesis	GO:0001525 GO:0004415 GO:0005509 GO:0005730 GO:0005829 GO:0005886 GO:0030214 GO:0030246 GO:0043231 GO:1903670