GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database Last Updated
MCAW-DB July 10, 2019
UniLectin June 14, 2023
UniProt Januarly 31, 2024
Lectin Frontier DataBase (LfDB) February 8, 2023
CarboGrove June 14, 2023
GlyCosmos Lectin Lectin Name UniProt ID Monosaccharide Specificities Species Taxonomy ID GO Labels GO IDs
Mannose-specific lectin 1
4460
  • extracellular region
  • mannose binding
  • response to other organism
  • GO:0005537
  • GO:0005576
  • GO:0051707
Concanavalin-A
  • Glc
  • Man
3823
  • defense response
  • mannose binding
  • metal ion binding
  • regulation of defense response to virus
  • GO:0005537
  • GO:0006952
  • GO:0046872
  • GO:0050688
E-selectin
10116
  • actin filament-based process
  • caveola
  • cell adhesion
  • clathrin-coated pit
  • cortical cytoskeleton
  • external side of plasma membrane
  • extracellular space
  • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
  • leukocyte cell-cell adhesion
  • leukocyte migration
  • leukocyte tethering or rolling
  • membrane raft
  • metal ion binding
  • oligosaccharide binding
  • perinuclear region of cytoplasm
  • phospholipase binding
  • plasma membrane
  • positive regulation of leukocyte migration
  • positive regulation of leukocyte tethering or rolling
  • positive regulation of receptor internalization
  • response to cytokine
  • response to interleukin-1
  • sialic acid binding
  • transmembrane signaling receptor activity
  • GO:0002092
  • GO:0002687
  • GO:0004888
  • GO:0005615
  • GO:0005886
  • GO:0005901
  • GO:0005905
  • GO:0007155
  • GO:0007157
  • GO:0007159
  • GO:0009897
  • GO:0030029
  • GO:0030863
  • GO:0033691
  • GO:0034097
  • GO:0043274
  • GO:0045121
  • GO:0046872
  • GO:0048471
  • GO:0050900
  • GO:0050901
  • GO:0070492
  • GO:0070555
  • GO:1903238
CCL2 lectin
5346
  • carbohydrate binding
  • GO:0030246
Hypothetical fimbrial-like protein ydeQ
199310
  • cell adhesion
  • pilus
  • GO:0007155
  • GO:0009289
L-type lectin-domain containing receptor kinase S.6
3702
  • ATP binding
  • carbohydrate binding
  • defense response to bacterium
  • defense response to oomycetes
  • phosphorylation
  • plasma membrane
  • protein serine kinase activity
  • protein serine/threonine kinase activity
  • GO:0002229
  • GO:0004674
  • GO:0005524
  • GO:0005886
  • GO:0016310
  • GO:0030246
  • GO:0042742
  • GO:0106310
Endosialin
10090
  • anatomical structure regression
  • calcium ion binding
  • carbohydrate binding
  • cell migration
  • cytoplasm
  • endothelial cell apoptotic process
  • external side of plasma membrane
  • extracellular matrix binding
  • extracellular matrix protein binding
  • fibroblast migration
  • fibroblast proliferation
  • lymph node development
  • plasma membrane
  • positive regulation of endothelial cell apoptotic process
  • positive regulation of fibroblast proliferation
  • GO:0005509
  • GO:0005737
  • GO:0005886
  • GO:0009897
  • GO:0010761
  • GO:0016477
  • GO:0030246
  • GO:0048144
  • GO:0048146
  • GO:0048535
  • GO:0050840
  • GO:0060033
  • GO:0072577
  • GO:1990430
  • GO:2000353
Chitinase-3-like protein 2
9606
  • carbohydrate binding
  • carbohydrate metabolic process
  • chitin binding
  • chitin catabolic process
  • extracellular region
  • extracellular space
  • hydrolase activity
  • GO:0005576
  • GO:0005615
  • GO:0005975
  • GO:0006032
  • GO:0008061
  • GO:0016787
  • GO:0030246
G-type lectin S-receptor-like serine/threonine-protein kinase SRK
3702
  • ATP binding
  • calmodulin binding
  • carbohydrate binding
  • defense response to bacterium
  • plasma membrane
  • protein autophosphorylation
  • protein serine kinase activity
  • protein serine/threonine kinase activity
  • recognition of pollen
  • ubiquitin protein ligase binding
  • GO:0004674
  • GO:0005516
  • GO:0005524
  • GO:0005886
  • GO:0030246
  • GO:0031625
  • GO:0042742
  • GO:0046777
  • GO:0048544
  • GO:0106310
Polypeptide N-acetylgalactosaminyltransferase 5
10090
  • Golgi apparatus
  • Golgi membrane
  • carbohydrate binding
  • metal ion binding
  • polypeptide N-acetylgalactosaminyltransferase activity
  • protein O-linked glycosylation
  • GO:0000139
  • GO:0004653
  • GO:0005794
  • GO:0006493
  • GO:0030246
  • GO:0046872
Displaying entries 1 - 10 of 2433 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01