GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID ▲	GO Labels	GO IDs
GL_000372	Extracellular exo-alpha-L-arabinofuranosidase	O54161	Streptomyces coelicolor A3(2)	100226	L-arabinose metabolic process alpha-L-arabinofuranosidase activity carbohydrate binding extracellular region xylan catabolic process	GO:0005576 GO:0030246 GO:0045493 GO:0046373 GO:0046556
GL_000680	Layilin	Q9Z209	Cricetulus griseus	10029	carbohydrate binding cell surface membrane ruffle	GO:0001726 GO:0009986 GO:0016020 GO:0030246
GL_000275	Calreticulin	Q8K3H7	Cricetulus griseus	10029	calcium ion binding carbohydrate binding cell surface cortical granule cytolytic granule cytosol extracellular region midbody protein folding protein stabilization sarcoplasmic reticulum lumen unfolded protein binding	GO:0005509 GO:0005576 GO:0005829 GO:0006457 GO:0009986 GO:0030246 GO:0030496 GO:0033018 GO:0044194 GO:0050821 GO:0051082 GO:0060473
GL_000477	Galectin-1	P48538	Cricetulus griseus	10029	T cell costimulation apoptotic process carbohydrate binding cell-cell adhesion cytosol extracellular space galectin complex myoblast differentiation plasma cell differentiation positive regulation of apoptotic process positive regulation of inflammatory response positive regulation of viral entry into host cell	GO:0002317 GO:0005615 GO:0005829 GO:0006915 GO:0030246 GO:0031295 GO:0043065 GO:0045445 GO:0046598 GO:0050729 GO:0098609 GO:1990724
GL_000498	Galectin-3	P47953	Cricetulus longicaudatus	10030	IgE binding RNA splicing carbohydrate binding cell differentiation cytoplasm extracellular region innate immune response mRNA processing spliceosomal complex	GO:0005576 GO:0005681 GO:0005737 GO:0006397 GO:0008380 GO:0019863 GO:0030154 GO:0030246 GO:0045087
GL_001103	Serum amyloid P-component	P07629	Mesocricetus auratus	10036	acute-phase response carbohydrate binding extracellular region metal ion binding	GO:0005576 GO:0006953 GO:0030246 GO:0046872
GL_001894	Zona pellucida sperm-binding protein 3	P23491	Mesocricetus auratus	10036	binding of sperm to zona pellucida blastocyst formation carbohydrate binding collagen-containing extracellular matrix egg coat egg coat formation extracellular space humoral immune response mediated by circulating immunoglobulin negative regulation of DNA-templated transcription negative regulation of binding of sperm to zona pellucida oocyte development plasma membrane positive regulation of DNA-templated transcription positive regulation of T cell proliferation positive regulation of acrosomal vesicle exocytosis positive regulation of acrosome reaction positive regulation of antral ovarian follicle growth positive regulation of humoral immune response positive regulation of inflammatory response positive regulation of interleukin-4 production positive regulation of leukocyte migration positive regulation of ovarian follicle development positive regulation of type II interferon production positive regulation of type IV hypersensitivity receptor ligand activity structural constituent of egg coat	GO:0001809 GO:0001825 GO:0002455 GO:0002687 GO:0002922 GO:0005615 GO:0005886 GO:0007339 GO:0030246 GO:0032729 GO:0032753 GO:0035803 GO:0035804 GO:0035805 GO:0042102 GO:0045892 GO:0045893 GO:0048018 GO:0048599 GO:0050729 GO:0062023 GO:2000344 GO:2000360 GO:2000368 GO:2000386 GO:2000388
GL_000769	Lymphocyte antigen 75	Q920P9	Mesocricetus auratus	10036	carbohydrate binding endocytosis membrane	GO:0006897 GO:0016020 GO:0030246
GL_000843	Pancreatic beta cell growth factor	Q92778	Mesocricetus auratus	10036	carbohydrate binding extracellular region	GO:0005576 GO:0030246
GL_001892	Zona pellucida sperm-binding protein 3	P10761	Mus musculus	10090	acrosin binding binding of sperm to zona pellucida blastocyst formation carbohydrate binding collagen-containing extracellular matrix egg coat egg coat formation extracellular matrix extracellular space humoral immune response mediated by circulating immunoglobulin identical protein binding negative regulation of DNA-templated transcription negative regulation of binding of sperm to zona pellucida oocyte development plasma membrane positive regulation of DNA-templated transcription positive regulation of T cell proliferation positive regulation of acrosomal vesicle exocytosis positive regulation of acrosome reaction positive regulation of antral ovarian follicle growth positive regulation of humoral immune response positive regulation of inflammatory response positive regulation of interleukin-4 production positive regulation of leukocyte migration positive regulation of ovarian follicle development positive regulation of type II interferon production positive regulation of type IV hypersensitivity receptor ligand activity regulation of signaling receptor activity structural constituent of egg coat	GO:0001809 GO:0001825 GO:0002455 GO:0002687 GO:0002922 GO:0005615 GO:0005886 GO:0007339 GO:0010469 GO:0030246 GO:0031012 GO:0032190 GO:0032729 GO:0032753 GO:0035803 GO:0035804 GO:0035805 GO:0042102 GO:0042802 GO:0045892 GO:0045893 GO:0048018 GO:0048599 GO:0050729 GO:0062023 GO:2000344 GO:2000360 GO:2000368 GO:2000386 GO:2000388