GlyCosmos Portal

GlyCosmos Lectins

Protein entries annotated as carbohydrate-binding in UniProt. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

Database	Last Updated
MCAW-DB	July 10, 2019
UniLectin	June 14, 2023
UniProt	February 16, 2024
Lectin Frontier DataBase (LfDB)	February 16, 2024
CarboGrove	June 14, 2023

GlyCosmos Lectin	Lectin Name	UniProt ID	Species	Taxonomy ID	GO Labels	GO IDs
GL_002003	E-selectin	P98107	Bos taurus	9913	actin filament-based process calcium ion binding caveola clathrin-coated pit cortical cytoskeleton external side of plasma membrane extracellular space heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte tethering or rolling oligosaccharide binding perinuclear region of cytoplasm phospholipase binding positive regulation of leukocyte migration positive regulation of leukocyte tethering or rolling positive regulation of receptor internalization response to cytokine response to interleukin-1 sialic acid binding transmembrane signaling receptor activity	GO:0002092 GO:0002687 GO:0004888 GO:0005509 GO:0005615 GO:0005901 GO:0005905 GO:0007157 GO:0009897 GO:0030029 GO:0030863 GO:0033691 GO:0034097 GO:0043274 GO:0048471 GO:0050901 GO:0070492 GO:0070555 GO:1903238
GL_002076	VIP36-like protein	P59481	Mus musculus	10090	COPII-coated ER to Golgi transport vesicle Golgi apparatus Golgi membrane endoplasmic reticulum membrane endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum-Golgi intermediate compartment mannose binding metal ion binding protein transport	GO:0000139 GO:0005537 GO:0005789 GO:0005793 GO:0005794 GO:0006888 GO:0015031 GO:0030134 GO:0046872
GL_000928	Polypeptide N-acetylgalactosaminyltransferase 6	Q8C7U7	Mus musculus	10090	Golgi apparatus Golgi membrane carbohydrate binding metal ion binding perinuclear region of cytoplasm polypeptide N-acetylgalactosaminyltransferase activity protein O-linked glycosylation protein O-linked glycosylation via threonine	GO:0000139 GO:0004653 GO:0005794 GO:0006493 GO:0018243 GO:0030246 GO:0046872 GO:0048471
GL_002315	Hemagglutinin (Fragment)	P03462	Influenza B virus (B/Hong Kong/8/1973)	427826	endocytosis involved in viral entry into host cell fusion of virus membrane with host endosome membrane fusion of virus membrane with host plasma membrane host cell plasma membrane host cell surface receptor binding membrane viral envelope virion attachment to host cell virion membrane	GO:0016020 GO:0019031 GO:0019062 GO:0019064 GO:0020002 GO:0039654 GO:0046789 GO:0055036 GO:0075509
GL_000081	B-cell receptor CD22	Q9N1E5	Pan paniscus	9597	B cell activation CD4 receptor binding carbohydrate binding cell adhesion early endosome external side of plasma membrane negative regulation of B cell receptor signaling pathway negative regulation of calcium-mediated signaling negative regulation of immunoglobulin production neuronal cell body membrane protein phosphatase binding recycling endosome regulation of B cell proliferation regulation of endocytosis sialic acid binding	GO:0002638 GO:0005769 GO:0007155 GO:0009897 GO:0019903 GO:0030100 GO:0030246 GO:0030888 GO:0032809 GO:0033691 GO:0042113 GO:0042609 GO:0050849 GO:0050859 GO:0055037
GL_001911	Frutapin	A0A2D0TC52	Artocarpus altilis	194251	carbohydrate binding	GO:0030246
GL_002124	Ecp6	B3VBK9	Fulvia fulva	5499
GL_002179	VP1	K4LM89	Norovirus Hu/GII.4/Sydney/NSW0514/2012/AU	1241973
GL_002334	Major capsid protein VP1	P0DOI3	KI polyomavirus Stockholm 60	423446	T=7 icosahedral viral capsid endocytosis involved in viral entry into host cell host cell nucleus structural molecule activity virion attachment to host cell	GO:0005198 GO:0019062 GO:0039620 GO:0042025 GO:0075509
GL_001647	Hematopoietic progenitor cell antigen CD34	Q64314	Mus musculus	10090	RNA polymerase II-specific DNA-binding transcription factor binding apical plasma membrane basal plasma membrane carbohydrate binding cell periphery cell surface cell-cell adhesion cell-matrix adhesion cytoplasm endothelial cell proliferation external side of plasma membrane extracellular exosome assembly extracellular region glomerular endothelium development glomerular endothelium fenestra glomerular filtration hematopoietic stem cell proliferation hemopoiesis intercellular bridge leukocyte migration lysosome membrane mesangial cell-matrix adhesion metanephric glomerular mesangial cell differentiation negative regulation of gene expression negative regulation of interleukin-2 production paracrine signaling perinuclear region of cytoplasm plasma membrane positive regulation of angiogenesis positive regulation of granulocyte colony-stimulating factor production positive regulation of odontogenesis positive regulation of vasculogenesis signal transduction sulfate binding tissue homeostasis transdifferentiation vascular wound healing	GO:0001894 GO:0001935 GO:0003094 GO:0005576 GO:0005737 GO:0005764 GO:0005886 GO:0007160 GO:0007165 GO:0009897 GO:0009925 GO:0009986 GO:0010629 GO:0016020 GO:0016324 GO:0030097 GO:0030246 GO:0032703 GO:0035759 GO:0036053 GO:0038001 GO:0042482 GO:0043199 GO:0045171 GO:0045766 GO:0048471 GO:0050900 GO:0060290 GO:0061042 GO:0061629 GO:0071425 GO:0071657 GO:0071944 GO:0071971 GO:0072011 GO:0072254 GO:0098609 GO:2001214