TRAF3-dependent IRF activation pathway
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- 1C
- CAP-1
- CBP
- CRAF1
- CREBBP
- DDX58
- EFP
- EP300
- IFB
- IFIH1
- IFNB
- IFNB1
- IKBKE
- IKKE
- IKKI
- IPS1
- IRF3
- IRF7
- KIAA0151
- KIAA1271
- M
- MAVS
- MDA5
- NAK
- NS1
- P300
- RH116
- RIGI
- RNF135
- RNF147
- RNF87
- SIKE
- SIKE1
- TBK1
- TRAF3
- TRAFAMN
- TRIM25
- TRIM4
- VISA
- ZNF147
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NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
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- CASP10
- CASP8
- CHUK
- DDX58
- EFP
- FADD
- FIP3
- IFIH1
- IKBKB
- IKBKG
- IKKA
- IKKB
- IPS1
- KIAA1271
- MAVS
- MCH4
- MCH5
- MDA5
- MORT1
- NEMO
- RH116
- RIGI
- RIP
- RIP1
- RIPK1
- RNF135
- RNF147
- RNF87
- TCF16
- TRIM25
- TRIM4
- VISA
- ZNF147
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Chylomicron remodeling
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- APC2
- APOA1
- APOA2
- APOA4
- APOA5
- APOB
- APOC2
- APOC3
- APOE
- GPIHBP1
- HBP1
- LIPD
- LPL
- RAP3
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Chylomicron assembly
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- APC2
- APOA1
- APOA2
- APOA4
- APOB
- APOC2
- APOC3
- APOE
- ERBA2L
- MTP
- MTTP
- P4HB
- PDI
- PDIA1
- PO4DB
- SAR1B
- SARA2
- SARB
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Scavenging by Class A Receptors
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- APOA1
- APOB
- APOE
- CALR
- CLP1
- COL1A1
- COL1A2
- COL3A1
- COL4A1
- COL4A2
- COLEC11
- COLEC12
- CRARF
- CRARF1
- CRTC
- FTH
- FTH1
- FTHL6
- FTL
- GRP94
- HSP90B1
- HSPC4
- MARCO
- MASP1
- MSR1
- NSR2
- PNSP1
- PRSS5
- SCARA1
- SCARA2
- SCARA4
- SCARA5
- SCGB3A2
- SRCL
- TRA1
- UGRP1
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Scavenging by Class B Receptors
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- APOA1
- APOB
- CD36
- GP3B
- GP4
- SAA1
- SSC5D
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HDL clearance
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- AMN
- APOA1
- CUBN
- HBP
- HDLBP
- IFCR
- VGL
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Defective ABCA1 causes TGD
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VLDL clearance
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- APOB
- APOB48R
- APOBR
- APOC1
- APOC4
- ILDR3
- LISCH
- LSR
- VLDLR
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VLDL assembly
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- APOB
- APOC1
- APOC4
- ERBA2L
- MTP
- MTTP
- P4HB
- PDI
- PDIA1
- PO4DB
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Chylomicron clearance
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- APOB
- APOE
- ARH
- HTGL
- LDLR
- LDLRAP1
- LIPC
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LDL remodeling
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- APOB
- APOF
- CETP
- ERBA2L
- LPA
- MTP
- MTTP
- P4HB
- PDI
- PDIA1
- PO4DB
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Cell surface interactions at the vascular wall
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- 2B4
- A15
- AMICA1
- APO2
- APOB
- AXLLG
- B1G1
- BCM1
- BGP
- BGP1
- BIT
- BLAST1
- C21orf43
- CAR
- CD11A
- CD11B
- CD11C
- CD177
- CD18
- CD2
- CD244
- CD43
- CD44
- CD47
- CD48
- CD49D
- CD58
- CD66D
- CD74
- CD84
- CD99
- CD99L2
- CEA
- CEACAM1
- CEACAM3
- CEACAM5
- CEACAM6
- CEACAM8
- CFR1
- CGM1
- CGM3
- CGM4
- CGM6
- CLEC8A
- CR3A
- CXADR
- CXCL4
- CXCL4V1
- DCR2
- DHLAG
- DR4
- DR5
- DXS1692E
- ELAM1
- EPCAM
- EPCR
- ESAM
- ESL1
- F11R
- F2
- FCAMR
- FCER1G
- FN
- FN1
- FNRA
- FNRB
- FYN
- GA733-2
- GAS6
- GLG1
- GLIF
- GLPC
- GMRP
- GP6
- GPA
- GPB
- GPC
- GPC1
- GRMP
- GYPA
- GYPB
- GYPC
- HSPG1
- IGCJ
- IGHA1
- IGHA2
- IGHM
- IGHV
- IGHV1-2
- IGHV1-46
- IGHV1-69
- IGHV2-5
- IGHV2-70
- IGHV3-11
- IGHV3-13
- IGHV3-23
- IGHV3-30
- IGHV3-33
- IGHV3-48
- IGHV3-53
- IGHV3-7
- IGHV3-9
- IGHV4-34
- IGHV4-39
- IGHV4-59
- IGHV7-81
- IGJ
- IGKC
- IGKV1-12
- IGKV1-16
- IGKV1-17
- IGKV1-33
- IGKV1-39
- IGKV1-5
- IGKV1D-12
- IGKV1D-16
- IGKV1D-33
- IGKV1D-39
- IGKV2-28
- IGKV2-29
- IGKV2-30
- IGKV2D-28
- IGKV2D-30
- IGKV2D-40
- IGKV3-11
- IGKV3-15
- IGKV3-20
- IGKV3D-20
- IGKV4-1
- IGKV5-2
- IGL1
- IGLC1
- IGLC2
- IGLC3
- IGLC6
- IGLC7
- IGLL1
- IGLV
- IGLV1-40
- IGLV1-44
- IGLV1-47
- IGLV1-51
- IGLV2-11
- IGLV2-14
- IGLV2-23
- IGLV2-8
- IGLV3-1
- IGLV3-19
- IGLV3-21
- IGLV3-25
- IGLV3-27
- IGLV6-57
- IGLV7-43
- ITGA4
- ITGA5
- ITGAL
- ITGAM
- ITGAX
- ITGB1
- ITGB2
- JAM1
- JAM2
- JAM3
- JAML
- JCAM
- JCHAIN
- JTK8
- KIAA0468
- KILLER
- LFA3
- LHR
- LNHR
- LOX1
- LYAM1
- LYN
- M1S2
- M4S1
- MDF2
- MDU2
- MDU3
- MER
- MER6
- MERTK
- MFI7
- MFR
- MG160
- MIC18
- MIC2
- MIC2L1
- MIC2X
- MIC2Y
- MIC4
- MIF
- MMIF
- MSK12
- MXS1
- MYD1
- NB1
- NCA
- OLR1
- PECAM1
- PF3D7_1301600
- PF4
- PF4V1
- PICK1
- PRKCABP
- PROC
- PROCR
- PROS
- PROS1
- PRV1
- PSBG1
- PSBG2
- PSG1
- PSG10
- PSG11
- PSG12
- PSG13
- PSG14
- PSG2
- PSG3
- PSG4
- PSG5
- PSG6
- PSG7
- PSG8
- PSG9
- PSGGA
- PSGGB
- PTPNS1
- SCYB4
- SCYB4V1
- SDC
- SDC1
- SDC2
- SDC3
- SDC4
- SELE
- SELL
- SELP
- SELPLG
- SHPS1
- SIRP
- SIRPA
- SIRPB2
- SIRPG
- SLAMF5
- SPN
- SRBC
- TACSTD1
- TGFB
- TGFB1
- THBD
- THRM
- TM4SF2
- TNFRSF10A
- TNFRSF10B
- TNFRSF10D
- TRAILR1
- TRAILR2
- TRAILR4
- TREM1
- TRICK2
- TROP1
- TRUNDD
- TSPAN7
- V1-11
- V1-13
- V1-16
- V1-20
- V1-3
- V1-5
- V1-7
- V1-9
- V2-11
- V2-15
- V2-17
- V2-19
- V2-8
- V3-2
- V3-3
- V3-4
- V4-1
- V4-2
- V4-6
- V5-1
- V5-4
- V5-6
- VEJAM
- VPREB
- VPREB1
- VPREB3
- ZTNFR9
- ebl-1
- opaA
- opaB
- opaC
- opaD
- opaE
- opaF
- opaG
- opaH
- opaI
- opaJ
- opaK
- piiC
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Scavenging by Class F Receptors
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- APOB
- CALR
- CRTC
- GRP170
- HSP105
- HSP110
- HSP90A
- HSP90AA1
- HSPC1
- HSPCA
- HSPH1
- HSPH4
- HYOU1
- KIAA0149
- KIAA0201
- ORP150
- SCARF1
- SREC
- porB
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Platelet sensitization by LDL
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- APOB
- APOER2
- CPLA2
- CSBP
- CSBP1
- CSBP2
- CSPB1
- FGR
- HCP
- KIAA0044
- LRP8
- MAPK14
- MXI2
- PECAM1
- PLA2G4
- PLA2G4A
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5C
- PPP2R5D
- PPP2R5E
- PTP1C
- PTP2C
- PTPN11
- PTPN6
- SAPK2A
- SHPTP2
- SRC2
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Regulation of TLR by endogenous ligand
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- APOB
- CAGA
- CAGB
- CD14
- CD36
- CFAG
- DFNA5
- DFNA5L
- ESOP1
- FGA
- FGB
- FGG
- GP3B
- GP4
- GSDMD
- GSDMDC1
- GSDME
- HMG1
- HMGB1
- ICERE1
- KIAA0012
- LBP
- LY96
- MD2
- MRP14
- MRP8
- S100A
- S100A1
- S100A8
- S100A9
- TIL4
- TLR1
- TLR2
- TLR4
- TLR6
- TLR7
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Scavenging by Class H Receptors
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- APOB
- FEEL1
- FEEL2
- FELL
- FEX2
- HARE
- KIAA0246
- ON
- SPARC
- STAB1
- STAB2
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Transport of fatty acids
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- ACSVL2
- ACSVL4
- ACSVL5
- APOD
- FACVL2
- FATP1
- FATP4
- FATP6
- LCN1
- LCN12
- LCN15
- LCN9
- SLC27A1
- SLC27A4
- SLC27A6
- VEGP
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Nuclear signaling by ERBB4
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- AD3
- AD4
- ADAM17
- ADAP1
- APH1A
- APH1B
- APOE
- BHLHC12
- BTC
- C1orf215
- CASB
- CENTA1
- CSN2
- CSVP
- CXCL12
- DTR
- DTS
- EREG
- ESR
- ESR1
- FOR
- GFAP
- GGF
- HBEGF
- HEGFL
- HGL
- HRGA
- KIAA0253
- KIAA0733
- KIAA1047
- LAP18
- MAD4
- MAP3K7IP2
- MXD4
- NCOR1
- NCSTN
- NDF
- NR3A1
- NR3C3
- NRG1
- NRG2
- NRG3
- NRG4
- NTAK
- ON
- OP18
- PEN2
- PGR
- PS1
- PS2
- PSEN1
- PSEN2
- PSENEN
- PSF
- PSFL
- PSNL1
- PSNL2
- S100B
- SDF1
- SDF1A
- SDF1B
- SDR41C1
- SMDF
- SPARC
- SRC
- SRC1
- STAT5
- STAT5A
- STM2
- STMN1
- TAB2
- TACE
- WOX1
- WWOX
- YAP1
- YAP65
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Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
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- AP2TF
- APOE
- DEK
- TFAP2
- TFAP2A
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TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
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- API4
- ASPP1
- ASPP2
- BBP
- BCL2L14
- BCL5
- BCL6
- BCLG
- BIRC5
- CAP43
- CHM
- DRG1
- GGTB
- IAP4
- KCP1
- KET
- KIAA0771
- KRTCAP1
- LAZ3
- NDRG1
- P53
- P63
- P73
- P73H
- P73L
- PERP
- PIG3
- PIGPC1
- PPP1R13B
- RABGGTA
- RABGGTB
- REP1
- RTP
- TCD
- THW
- TP53
- TP53BP2
- TP53I3
- TP63
- TP73
- TP73L
- ZBTB27
- ZNF51
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Suppression of apoptosis
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- ALO17
- C17orf27
- CTSG
- ERK1
- ERK2
- GSK3A
- KIAA1554
- KIAA1618
- MAPK1
- MAPK3
- MYSTR
- PRKM1
- PRKM2
- PRKM3
- PSF
- RFP
- RNF213
- RNF76
- Rv3364c
- Rv3654c
- Rv3655c
- SFPQ
- TRIM27
- lprM
- mce3E
- mptpA
- ptpA
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TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
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- 15E1.1
- AIFM2
- AMID
- ASPP1
- ASPP2
- ATM
- BAX
- BBC3
- BBP
- BCL2L4
- BID
- BNIP3A
- BNIP3H
- BNIP3L
- C18orf43
- CBP
- CREBBP
- KET
- KIAA0771
- NIX
- NOXA
- P53
- P53DINP1
- P63
- P73
- P73H
- P73L
- PMAIP1
- PPP1R13B
- PRELI
- PRELID1
- PRELID3A
- PRG3
- PUMA
- SIP
- SLMO1
- STEAP3
- TP53
- TP53AIP1
- TP53BP2
- TP53INP1
- TP63
- TP73
- TP73L
- TRIAP1
- TSAP6
- ZNF420
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Activation, translocation and oligomerization of BAX
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Pyroptosis
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- BAK
- BAK1
- BAX
- BC2
- BCL2L4
- BCL2L7
- C14orf123
- C20orf178
- CASP1
- CASP3
- CASP4
- CASP5
- CDN1
- CGI149
- CGL1
- CHMP2
- CHMP2A
- CHMP2B
- CHMP3
- CHMP4A
- CHMP4B
- CHMP4C
- CHMP6
- CHMP7
- CPP32
- CSPB
- CTLA1
- CYC
- CYCS
- DFNA5
- DFNA5L
- ELA2
- ELANE
- GRB
- GSDMD
- GSDMDC1
- GSDME
- GZMB
- HMG1
- HMGB1
- ICERE1
- ICH2
- ICH3
- IGIF
- IL18
- IL1A
- IL1B
- IL1BC
- IL1BCE
- IL1F1
- IL1F2
- IL1F4
- IRF1
- IRF2
- KET
- NEDF
- P53
- P63
- P73H
- P73L
- SHAX1
- SHAX2
- SHAX3
- TP53
- TP63
- TP73L
- VPS20
- VPS24
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