Regulation of RUNX1 Expression and Activity
|
|
|
- AGO1
- AGO2
- AGO3
- AGO4
- AML1
- BCL1
- CAGH26
- CBFA2
- CBFB
- CCND1
- CCND2
- CCND3
- CDK6
- CDKN6
- EIF2C1
- EIF2C2
- EIF2C3
- EIF2C4
- KIAA1093
- KIAA1460
- KIAA1567
- KIAA1582
- KIAA1631
- MOV10
- MYL
- PML
- PP8675
- PRAD1
- PTP2C
- PTPN11
- RNF71
- RUNX1
- SHPTP2
- SRC
- SRC1
- TNRC6
- TNRC6A
- TNRC6B
- TNRC6C
- TRIM19
|
|
Ion influx/efflux at host-pathogen interface
|
|
|
- AIPP1
- ATOX1
- ATP7A
- HAH1
- LSH
- MC1
- MNK
- NRAMP
- NRAMP1
- PDZD11
- PDZK11
- PISP
- SLC11A1
|
|
NOTCH2 Activation and Transmission of Signal to the Nucleus
|
|
|
- AD3
- AD4
- ADAM10
- APH1A
- APH1B
- CNTN1
- DIP1
- DLL1
- DLL4
- JAG1
- JAG2
- JAGL1
- KIAA0253
- KIAA1323
- KUZ
- MADM
- MDK
- MIB1
- MIB2
- MK1
- NCSTN
- NEGF2
- NEURL
- NEURL1
- NEURL1A
- NEURL1B
- NEURL3
- NOTCH2
- PEN2
- PS1
- PS2
- PSEN1
- PSEN2
- PSENEN
- PSF
- PSFL
- PSNL1
- PSNL2
- RNF67
- RPS27A
- SKD
- STM2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- ZZANK1
- ZZANK2
|
|
Condensation of Prophase Chromosomes
|
|
|
- CAPC
- CAPD3
- CAPE
- CAPH2
- CCNB
- CCNB1
- CDC2
- CDC28A
- CDK1
- CDKN1
- H2AB1
- H2AC14
- H2AC18
- H2AC19
- H2AC20
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFB1
- H2AFE
- H2AFG
- H2AFJ
- H2AFL
- H2AFM
- H2AFO
- H2AFQ
- H2AFV
- H2AFX
- H2AJ
- H2AV
- H2AX
- H2AZ2
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H3-3A
- H3-3B
- H3-4
- H3.3A
- H3.3B
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3F3
- H3F3A
- H3F3B
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- H3FT
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HIRIP1
- HIRIP2
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AJ
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AC
- HIST2H2BE
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST3H3
- HIST4H4
- KIAA0056
- KMT5A
- LUZP5
- MCPH1
- NCAPD3
- NCAPG2
- NCAPH2
- P34CDC2
- PLK
- PLK1
- PRSET7
- RB1
- SET
- SET07
- SET8
- SETD8
- SMC2
- SMC2L1
- SMC4
- SMC4L1
- TSH2B
|
|
Serotonin Neurotransmitter Release Cycle
|
|
|
- BZRAP1
- CPLX1
- KIAA0340
- KIAA0612
- KIAA0654
- KIAA0897
- LIP1
- PPFIA1
- PPFIA2
- PPFIA3
- PPFIA4
- RAB3A
- RAB3IP2
- RBP1
- RIM1
- RIMBP1
- RIMS1
- SLC18A2
- SNAP
- SNAP25
- STX1
- STX1A
- SVMT
- SVP65
- SYB2
- SYN1
- SYN2
- SYN3
- SYT
- SYT1
- TSPOAP1
- UNC13
- UNC13B
- VAMP2
- VMAT2
|
|
Glutamate Neurotransmitter Release Cycle
|
|
|
- ARL6IP5
- ATA2
- BNPI
- BZRAP1
- CPLX1
- DERP11
- EAAC1
- EAAT1
- EAAT2
- EAAT3
- EAAT4
- EAAT5
- GA
- GLAST
- GLAST1
- GLS
- GLS1
- GLS2
- GLT1
- HEAAC1
- JWA
- KIAA0340
- KIAA0612
- KIAA0654
- KIAA0838
- KIAA0897
- KIAA1382
- LIP1
- PPFIA1
- PPFIA2
- PPFIA3
- PPFIA4
- PRA2
- PRAF3
- RAB3A
- RAB3IP2
- RBP1
- RIM1
- RIMBP1
- RIMS1
- SAT2
- SLC17A7
- SLC1A1
- SLC1A2
- SLC1A3
- SLC1A6
- SLC1A7
- SLC38A2
- SNAP
- SNAP25
- SNAT2
- STX1
- STX1A
- SVP65
- SYB2
- SYT
- SYT1
- TSPOAP1
- UNC13
- UNC13B
- VAMP2
- VGLUT1
|
|
GABA synthesis, release, reuptake and degradation
|
|
|
- CLN4
- CPLX1
- DNAJC5
- GAD
- GAD1
- GAD2
- GAD65
- GAD67
- HSC70
- HSP73
- HSPA10
- HSPA8
- KIAA0340
- RAB3A
- RAB3IP2
- RIM1
- RIMS1
- SLC32A1
- SNAP
- SNAP25
- STX1
- STX1A
- SVP65
- SYB2
- SYT
- SYT1
- VAMP2
- VGAT
- VIAAT
|
|
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
|
|
|
- AITR
- AML1
- C3BR
- CBFA2
- CBFB
- CD152
- CR1
- CTLA4
- FOXP3
- GITR
- IFNG
- IL2
- IL2RA
- IPEX
- NFAT1
- NFATC2
- NFATP
- RUNX1
- TNFRSF18
|
|
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function
|
|
|
- C1QBP
- CDKN2
- CDKN2A
- GC1QBP
- HABP1
- MLM
- SF2P32
|
|
Apoptotic factor-mediated response
|
|
|
- C1QBP
- CDKN2
- CDKN2A
- GC1QBP
- HABP1
- MLM
- SF2P32
|
|
Alternative complement activation
|
|
|
- BF
- BFD
- C3
- CFB
- CFD
- CPAMD1
- DF
- GZMM
- MET1
- PFD
|
|
Activation of C3 and C5
|
|
|
- BF
- BFD
- C2
- C3
- C4A
- C4B
- C4B_2
- C5
- CFB
- CO4
- CPAMD1
- CPAMD2
- CPAMD3
- CPAMD4
|
|
Lectin pathway of complement activation
|
|
|
- CLL1
- COLEC1
- COLEC10
- COLEC11
- CRARF
- CRARF1
- FCN1
- FCN2
- FCN3
- FCNH
- FCNL
- FCNM
- HAKA1
- MASP1
- MBL
- MBL2
- PRSS5
|
|
Initial triggering of complement
|
|
|
- C1QA
- C1QB
- C1QC
- C1QG
- C1R
- C1S
- C2
- C4A
- C4B
- C4B_2
- CLL1
- CO4
- COLEC1
- COLEC10
- COLEC11
- CPAMD2
- CPAMD3
- CRARF
- CRARF1
- FCN1
- FCN2
- FCN3
- FCNH
- FCNL
- FCNM
- HAKA1
- IGHG1
- IGHG2
- IGHG3
- IGHG4
- IGHV
- IGHV1-2
- IGHV1-46
- IGHV1-69
- IGHV2-5
- IGHV2-70
- IGHV3-11
- IGHV3-13
- IGHV3-23
- IGHV3-30
- IGHV3-33
- IGHV3-48
- IGHV3-53
- IGHV3-7
- IGHV3-9
- IGHV4-34
- IGHV4-39
- IGHV4-59
- IGHV7-81
- IGKC
- IGKV1-12
- IGKV1-16
- IGKV1-17
- IGKV1-33
- IGKV1-39
- IGKV1-5
- IGKV1D-12
- IGKV1D-16
- IGKV1D-33
- IGKV1D-39
- IGKV2-28
- IGKV2-29
- IGKV2-30
- IGKV2D-28
- IGKV2D-30
- IGKV2D-40
- IGKV3-11
- IGKV3-15
- IGKV3-20
- IGKV3D-20
- IGKV4-1
- IGKV5-2
- IGLC1
- IGLC2
- IGLC3
- IGLC6
- IGLC7
- IGLV
- IGLV1-40
- IGLV1-44
- IGLV1-47
- IGLV1-51
- IGLV2-11
- IGLV2-14
- IGLV2-23
- IGLV2-8
- IGLV3-1
- IGLV3-19
- IGLV3-21
- IGLV3-25
- IGLV3-27
- IGLV6-57
- IGLV7-43
- MASP1
- MBL
- MBL2
- PRSS5
- V1-11
- V1-13
- V1-16
- V1-20
- V1-3
- V1-5
- V1-7
- V1-9
- V2-11
- V2-15
- V2-17
- V2-19
- V2-8
- V3-2
- V3-3
- V3-4
- V4-1
- V4-2
- V4-6
- V5-1
- V5-4
- V5-6
|
|
RUNX2 regulates genes involved in cell migration
|
|
|
- AKT1
- AKT2
- AKT3
- CBFB
- FNRA
- ITGA5
- ITGBL1
- MMP13
- OSCP
- PKB
- PKBG
- RAC
- TIED
|
|
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
|
|
|
- BHLHE39
- CCNC
- CCNK
- CCNT1
- CCNT2
- CDC2L4
- CDK8
- CDK9
- CDKN2B
- COL1A2
- CPR4
- DP1
- DP2
- DPC4
- E2F4
- E2F5
- EP300
- ERK1
- ERK2
- FUR
- FURIN
- HDAC1
- JUNB
- MADH2
- MADH3
- MADH4
- MADH7
- MADH8
- MADR2
- MAPK1
- MAPK3
- MEN1
- MTS2
- MYC
- NSEP1
- P300
- PACE
- PAI1
- PCSK3
- PLANH1
- PRKM1
- PRKM2
- PRKM3
- RBL1
- RNF111
- RPD3L1
- RPS27A
- SCG2
- SERPINE1
- SMAD2
- SMAD3
- SMAD4
- SMAD7
- SP1
- TAK
- TAZ
- TFDP1
- TFDP2
- TGIF
- TGIF1
- TGIF2
- TSFP1
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- WWTR1
- YB1
- YBX1
|
|
Signaling by PDGF
|
|
|
- BNSP
- COL29A1
- COL4A1
- COL4A2
- COL4A3
- COL4A4
- COL4A5
- COL6A1
- COL6A2
- COL6A3
- COL6A5
- COL6A6
- COL9A1
- COL9A2
- COL9A3
- FUR
- FURIN
- IEGF
- OPN
- PACE
- PCSK3
- PDGF2
- PDGFB
- PDGFD
- PDGFR
- PDGFR1
- PDGFR2
- PDGFRA
- PDGFRB
- PLAT
- PLG
- PTPN12
- RHEPDGFRA
- SCDGFB
- SIS
- SPP1
- THBS1
- THBS2
- THBS3
- THBS4
- TSP
- TSP1
- TSP2
- TSP3
- TSP4
- VWA4
|
|
Collagen chain trimerization
|
|
|
- BP180
- BPAG2
- C3orf7
- COL10A1
- COL11A1
- COL11A2
- COL12A1
- COL12A1L
- COL13A1
- COL14A1
- COL15A1
- COL16A1
- COL17A1
- COL18A1
- COL19A1
- COL1A1
- COL1A2
- COL1AL
- COL20A1
- COL21A1
- COL22A1
- COL23A1
- COL24A1
- COL25A1
- COL26A1
- COL27A1
- COL28
- COL28A1
- COL29A1
- COL2A1
- COL3A1
- COL4A1
- COL4A2
- COL4A3
- COL4A4
- COL4A5
- COL4A6
- COL5A1
- COL5A2
- COL5A3
- COL6A1
- COL6A2
- COL6A3
- COL6A5
- COL6A6
- COL7A1
- COL8A1
- COL8A2
- COL9A1
- COL9A2
- COL9A3
- COLL6
- EMID2
- EMU2
- KIAA1510
- KIAA1870
- UND
- VWA4
|
|
Establishment of Sister Chromatid Cohesion
|
|
|
- APRIN
- AS3
- BAM
- BMH
- CDCA5
- CSPG6
- DXS423E
- EFO1
- ESCO1
- ESCO2
- FOE
- HR21
- KIAA0078
- KIAA0178
- KIAA0261
- KIAA0648
- KIAA0979
- KIAA1911
- NXP1
- PDS5
- PDS5A
- PDS5B
- RAD21
- SA1
- SA2
- SB1.8
- SCC1
- SCC3
- SMC1
- SMC1A
- SMC1L1
- SMC3
- SMC3L1
- STAG1
- STAG2
- WAPAL
- WAPL
|
|
Cohesin Loading onto Chromatin
|
|
|
- APRIN
- AS3
- BAM
- BMH
- CSPG6
- DXS423E
- FOE
- HR21
- IDN3
- KIAA0078
- KIAA0178
- KIAA0261
- KIAA0648
- KIAA0892
- KIAA0979
- MAU2
- NIPBL
- NXP1
- PDS5
- PDS5A
- PDS5B
- RAD21
- SA1
- SA2
- SB1.8
- SCC1
- SCC2
- SCC3
- SCC4
- SMC1
- SMC1A
- SMC1L1
- SMC3
- SMC3L1
- STAG1
- STAG2
- WAPAL
- WAPL
|
|
RHO GTPases Activate ROCKs
|
|
|
- ARH12
- ARH6
- ARH9
- ARHA
- ARHB
- ARHC
- CFL
- CFL1
- KIAA0619
- KIAA0866
- KIAA2034
- LIMK
- LIMK1
- LIMK2
- MBS
- MLC2
- MRLC1
- MRLC2
- MYH10
- MYH11
- MYH14
- MYH9
- MYL12B
- MYL6
- MYL9
- MYLC2B
- MYPT1
- MYPT2
- MYRL2
- PAK1
- PPP1CB
- PPP1R12A
- PPP1R12B
- RHO12
- RHOA
- RHOB
- RHOC
- ROCK1
- ROCK2
|
|
Sema3A PAK dependent Axon repulsion
|
|
|
- CFL
- CFL1
- FES
- FPS
- FYN
- HSP90A
- HSP90AA1
- HSP90AB1
- HSP90B
- HSPC1
- HSPC2
- HSPC3
- HSPCA
- HSPCB
- KIAA0463
- KIAA1550
- LIMK
- LIMK1
- NOV
- NRP
- NRP1
- OCT
- OPHN3
- PAK1
- PAK2
- PAK3
- PLXN1
- PLXN2
- PLXN4
- PLXNA1
- PLXNA2
- PLXNA3
- PLXNA4
- PLXNA4A
- PLXNA4B
- RAC1
- SEMA3A
- SEMAD
- SEX
- TC25
- VEGF165R
|
|
Cobalamin (Cbl) metabolism
|
|
|
- C2orf25
- CL25022
- MMAA
- MMAB
- MMACHC
- MMADHC
- MMUT
- MTR
- MTRR
- MUT
|
|
Defective CBLIF causes IFD
|
|
|
|
|
Defective AMN causes MGA1
|
|
|
- AMN
- CBLIF
- CUBN
- GIF
- IFCR
- IFMH
|
|