GlyCosmos Portal

Homo sapiens (human)

Summary

Taxonomy ID: 9606
PubChem Taxonomy: 9606

Genes (1582) Glycans (5831) Glycoproteins (18496) Lectins (298) Pathways (2090)

Displaying entries **826 - 850** of **2090** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol
Regulation of cholesterol biosynthesis by SREBP (SREBF)	GTP-binding nuclear protein Ran Importin subunit beta-1 Insulin-induced gene 1 protein Insulin-induced gene 2 protein Membrane-bound transcription factor site-1 protease Membrane-bound transcription factor site-2 protease Protein transport protein Sec23A Protein transport protein Sec24A Protein transport protein Sec24B Protein transport protein Sec24C Protein transport protein Sec24D Small COPII coat GTPase SAR1B Sterol regulatory element-binding protein 2 Sterol regulatory element-binding protein cleavage-activating protein	O15503 O43462 O94855 O95486 O95487 P53992 P62826 Q12770 Q12772 Q14703 Q14974 Q15436 Q9Y5U4 Q9Y6B6	ARA24 BHLHD2 INSIG1 INSIG2 KIAA0079 KIAA0091 KIAA0199 KIAA0755 KPNB1 MBTPS1 MBTPS2 NTF97 RAN S1P S2P SAR1B SARA2 SARB SCAP SEC23A SEC24A SEC24B SEC24C SEC24D SKI1 SREBF2 SREBP2
FGFR2 alternative splicing	Cytotoxic granule associated RNA binding protein TIA1 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Epithelial splicing regulatory protein 1 Epithelial splicing regulatory protein 2 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Heterogeneous nuclear ribonucleoprotein A1 Heterogeneous nuclear ribonucleoprotein F Heterogeneous nuclear ribonucleoprotein H Heterogeneous nuclear ribonucleoprotein M Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nucleolysin TIAR Polypyrimidine tract-binding protein 1 RNA binding protein fox-1 homolog 2	O15514 O43251 P09651 P13984 P19387 P19388 P24928 P26599 P30876 P31483 P31943 P35269 P36954 P52272 P52298 P52434 P52435 P52597 P53803 P61218 P62487 P62875 Q01085 Q09161 Q6NXG1 Q9H6T0	CBP20 CBP80 ESRP1 ESRP2 FOX2 GTF2F1 GTF2F2 HNRNPA1 HNRNPF HNRNPH1 HNRNPM HNRPA1 HNRPF HNRPH HNRPH1 HNRPM HRNBP2 NAGR1 NCBP NCBP1 NCBP2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PTB PTBP1 RAP30 RAP74 RBFOX2 RBM35A RBM35B RBM9 RPB7 RTA TIA1 TIAL1
Processing of Capped Intron-Containing Pre-mRNA	Cleavage and polyadenylation specificity factor subunit 1 Cleavage and polyadenylation specificity factor subunit 2 Cleavage and polyadenylation specificity factor subunit 3 Cleavage and polyadenylation specificity factor subunit 4 Cleavage and polyadenylation specificity factor subunit 5 Cleavage and polyadenylation specificity factor subunit 7 Cleavage stimulation factor subunit 1 Cleavage stimulation factor subunit 2 tau variant Cleavage stimulation factor subunit 2 Cleavage stimulation factor subunit 3 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Heterogeneous nuclear ribonucleoprotein A1 Heterogeneous nuclear ribonucleoprotein A3 Heterogeneous nuclear ribonucleoprotein D0 Heterogeneous nuclear ribonucleoprotein F Heterogeneous nuclear ribonucleoprotein H2 Heterogeneous nuclear ribonucleoprotein H Heterogeneous nuclear ribonucleoprotein K Heterogeneous nuclear ribonucleoprotein L Heterogeneous nuclear ribonucleoprotein M Heterogeneous nuclear ribonucleoprotein R Heterogeneous nuclear ribonucleoprotein U Heterogeneous nuclear ribonucleoproteins A2/B1 Heterogeneous nuclear ribonucleoproteins C1/C2 N6-adenosine-methyltransferase catalytic subunit N6-adenosine-methyltransferase non-catalytic subunit Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Poly(A) polymerase alpha Poly(rC)-binding protein 1 Poly(rC)-binding protein 2 Polyadenylate-binding protein 2 Polypyrimidine tract-binding protein 1 Polyribonucleotide 5'-hydroxyl-kinase Clp1 Pre-mRNA 3'-end-processing factor FIP1 Pre-mRNA cleavage complex 2 protein Pcf11 Pre-mRNA-splicing regulator WTAP RNA-binding motif protein, X chromosome RNA-binding protein 10 RNA-binding protein FUS Serine/arginine-rich splicing factor 10 Serine/arginine-rich splicing factor 11 Serine/arginine-rich splicing factor 12 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 3 Serine/arginine-rich splicing factor 4 Serine/arginine-rich splicing factor 5 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Serine/arginine-rich splicing factor 8 Serine/arginine-rich splicing factor 9 Symplekin Transformer-2 protein homolog beta Y-box-binding protein 1 pre-mRNA 3' end processing protein WDR33	O15514 O43390 O43809 O75494 O94913 O95639 P07910 P09651 P13984 P14866 P19387 P19388 P22626 P24928 P26599 P30876 P31943 P33240 P35269 P35637 P36954 P38159 P51003 P51991 P52272 P52298 P52434 P52435 P52597 P53803 P55795 P61218 P61978 P62487 P62875 P62995 P67809 P84103 P98175 Q00839 Q01130 Q05048 Q05519 Q07955 Q08170 Q09161 Q10570 Q12996 Q13242 Q13243 Q13247 Q14103 Q15007 Q15365 Q15366 Q16629 Q6UN15 Q86U42 Q86U44 Q8N684 Q8WXF0 Q92797 Q92989 Q9BRL6 Q9C0J8 Q9H0L4 Q9HCE5 Q9P2I0 Q9UKF6	ASF AUF1 C1orf199 CBP20 CBP80 CFIM25 CLP1 CPSF1 CPSF100 CPSF160 CPSF2 CPSF25 CPSF3 CPSF30 CPSF4 CPSF5 CPSF7 CPSF73 CSTF1 CSTF2 CSTF2T CSTF3 DXS8237E FIP1 FIP1L1 FTP3 FUS FUSIP1 FUSIP2 GPATC9 GPATCH9 GTF2F1 GTF2F2 HEAB HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPL HNRNPM HNRNPR HNRNPU HNRPA1 HNRPA2B1 HNRPA3 HNRPC HNRPD HNRPF HNRPG HNRPH HNRPH1 HNRPH2 HNRPK HNRPL HNRPM HNRPR HNRPU HRS KIAA0105 KIAA0122 KIAA0689 KIAA0824 KIAA1367 KIAA1627 METTL14 METTL3 MTA70 NAGR1 NAR NCBP NCBP1 NCBP2 NEB1 NSEP1 NUDT21 PAB2 PABP2 PABPN1 PAP PAPOLA PCBP1 PCBP2 PCF11 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PTB PTBP1 RAP30 RAP74 RBM10 RBMX RBMXP1 RHE RPB7 SAFA SF2 SF2P33 SFRS1 SFRS10 SFRS11 SFRS13A SFRS13B SFRS19 SFRS2 SFRS2B SFRS3 SFRS4 SFRS5 SFRS6 SFRS7 SFRS9 SPK SRP20 SRP30C SRP40 SRP46 SRP55 SRP75 SRRP35 SRSF1 SRSF10 SRSF11 SRSF12 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SRSF9 SYMPK TASR TLS TRA2B U21.1 WDC146 WDR33 WTAP YB1 YBX1
Dual incision in TC-NER	CDK-activating kinase assembly factor MAT1 Cullin-4A Cullin-4B Cyclin-H Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA excision repair protein ERCC-1 DNA excision repair protein ERCC-5 DNA excision repair protein ERCC-6 DNA excision repair protein ERCC-8 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA polymerase kappa DNA repair endonuclease XPF DNA repair protein complementing XP-A cells DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Peptidyl-prolyl cis-trans isomerase E Polyubiquitin-B Polyubiquitin-C Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor ISY1 homolog Pre-mRNA-splicing factor SYF1 Proliferating cell nuclear antigen RNA helicase aquarius Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Transcription elongation factor A protein 1 UV-stimulated scaffold protein A Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein 830	O15514 O60306 P07992 P0CG47 P0CG48 P12004 P15927 P18074 P19387 P19388 P19447 P23025 P23193 P24928 P27694 P28340 P28715 P30876 P32780 P35244 P35249 P35250 P35251 P36954 P40937 P40938 P49005 P50613 P51946 P51948 P52434 P52435 P53803 P56282 P61218 P62487 P62875 P62877 P62979 P62987 Q03468 Q07864 Q13216 Q13619 Q13620 Q13888 Q13889 Q15054 Q16531 Q2YD98 Q6ZYL4 Q92759 Q92889 Q93009 Q96NB3 Q9HCS7 Q9HCU8 Q9NR33 Q9NRF9 Q9UBT6 Q9ULR0 Q9UMS4 Q9UNP9	AQR BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CCDC16 CCNH CDK7 CDKN7 CHRAC17 CKN1 CSA CSB CUL4A CUL4B CYP33 DDB1 DINB1 DPE2 ERCC1 ERCC11 ERCC2 ERCC3 ERCC4 ERCC5 ERCC6 ERCC8 ERCM2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S HAUSP HCNP ISY1 KIAA0039 KIAA0560 KIAA0695 KIAA1160 KIAA1177 KIAA1530 MAT1 MNAT1 MO15 NMP200 PCNA POLD POLD1 POLD2 POLD3 POLD4 POLDS POLE POLE1 POLE2 POLE3 POLE4 POLK POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PPIE PRP19 PRPF19 RBX1 REPA1 REPA2 REPA3 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RNF66 RNF75 ROC1 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPB7 RPS27A SNEV STK1 SYF1 TCEA1 TFIIS TTDA UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP7 UVSSA XAB2 XAP1 XPA XPAC XPB XPBC XPD XPDC XPF XPG XPGC ZNF830
Gap-filling DNA repair synthesis and ligation in TC-NER	CDK-activating kinase assembly factor MAT1 Cullin-4A Cullin-4B Cyclin-H Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA excision repair protein ERCC-6 DNA excision repair protein ERCC-8 DNA ligase 1 DNA ligase 3 DNA polymerase delta catalytic subunit DNA polymerase delta subunit 2 DNA polymerase delta subunit 3 DNA polymerase delta subunit 4 DNA polymerase epsilon catalytic subunit A DNA polymerase epsilon subunit 2 DNA polymerase epsilon subunit 3 DNA polymerase epsilon subunit 4 DNA polymerase kappa DNA repair protein XRCC1 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Peptidyl-prolyl cis-trans isomerase E Polyubiquitin-B Polyubiquitin-C Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor ISY1 homolog Pre-mRNA-splicing factor SYF1 Proliferating cell nuclear antigen RNA helicase aquarius Replication factor C subunit 1 Replication factor C subunit 2 Replication factor C subunit 3 Replication factor C subunit 4 Replication factor C subunit 5 Replication protein A 14 kDa subunit Replication protein A 32 kDa subunit Replication protein A 70 kDa DNA-binding subunit Transcription elongation factor A protein 1 UV-stimulated scaffold protein A Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein 830	O15514 O60306 P0CG47 P0CG48 P12004 P15927 P18074 P18858 P18887 P19387 P19388 P19447 P23193 P24928 P27694 P28340 P30876 P32780 P35244 P35249 P35250 P35251 P36954 P40937 P40938 P49005 P49916 P50613 P51946 P51948 P52434 P52435 P53803 P56282 P61218 P62487 P62875 P62877 P62979 P62987 Q03468 Q07864 Q13216 Q13619 Q13620 Q13888 Q13889 Q15054 Q16531 Q2YD98 Q6ZYL4 Q92759 Q93009 Q96NB3 Q9HCS7 Q9HCU8 Q9NR33 Q9NRF9 Q9UBT6 Q9ULR0 Q9UMS4 Q9UNP9	AQR BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CCDC16 CCNH CDK7 CDKN7 CHRAC17 CKN1 CSA CSB CUL4A CUL4B CYP33 DDB1 DINB1 DPE2 ERCC2 ERCC3 ERCC6 ERCC8 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S HAUSP HCNP ISY1 KIAA0039 KIAA0560 KIAA0695 KIAA1160 KIAA1177 KIAA1530 LIG1 LIG3 MAT1 MNAT1 MO15 NMP200 PCNA POLD POLD1 POLD2 POLD3 POLD4 POLDS POLE POLE1 POLE2 POLE3 POLE4 POLK POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PPIE PRP19 PRPF19 RBX1 REPA1 REPA2 REPA3 RFC1 RFC140 RFC2 RFC3 RFC4 RFC5 RNF66 RNF75 ROC1 RPA1 RPA14 RPA2 RPA3 RPA32 RPA34 RPA70 RPB7 RPS27A SNEV STK1 SYF1 TCEA1 TFIIS TTDA UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP7 UVSSA XAB2 XAP1 XPB XPBC XPD XPDC XRCC1 ZNF830
Formation of TC-NER Pre-Incision Complex	CDK-activating kinase assembly factor MAT1 COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 5 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 7a COP9 signalosome complex subunit 7b COP9 signalosome complex subunit 8 Cullin-4A Cullin-4B Cyclin-H Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA excision repair protein ERCC-6 DNA excision repair protein ERCC-8 DNA repair protein complementing XP-A cells DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Peptidyl-prolyl cis-trans isomerase E Polyubiquitin-B Polyubiquitin-C Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor ISY1 homolog Pre-mRNA-splicing factor SYF1 RNA helicase aquarius Transcription elongation factor A protein 1 UV-stimulated scaffold protein A Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein 830	O15514 O60306 P0CG47 P0CG48 P18074 P19387 P19388 P19447 P23025 P23193 P24928 P30876 P32780 P36954 P50613 P51946 P51948 P52434 P52435 P53803 P61201 P61218 P62487 P62875 P62877 P62979 P62987 Q03468 Q13098 Q13216 Q13619 Q13620 Q13888 Q13889 Q16531 Q2YD98 Q6ZYL4 Q7L5N1 Q92759 Q92905 Q93009 Q96NB3 Q99627 Q9BT78 Q9H9Q2 Q9HCS7 Q9UBW8 Q9ULR0 Q9UMS4 Q9UNP9 Q9UNS2	AQR BTF2 BTF2P44 C6orf175 CAK CAK1 CAP35 CCDC16 CCNH CDK7 CDKN7 CKN1 COPS1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 CSA CSB CSN1 CSN2 CSN3 CSN4 CSN5 CSN6 CSN7A CSN7B CSN8 CUL4A CUL4B CYP33 DDB1 DERP10 ERCC2 ERCC3 ERCC6 ERCC8 GPS1 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S HAUSP HCNP HVIP ISY1 JAB1 KIAA0560 KIAA0695 KIAA1160 KIAA1177 KIAA1530 MAT1 MNAT1 MO15 NMP200 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PPIE PRP19 PRPF19 RBX1 RNF66 RNF75 ROC1 RPB7 RPS27A SNEV STK1 SYF1 TCEA1 TFIIS TRIP15 TTDA UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP7 UVSSA XAB2 XAP1 XPA XPAC XPB XPBC XPD XPDC ZNF830
Transcription-Coupled Nucleotide Excision Repair (TC-NER)	CDK-activating kinase assembly factor MAT1 Cullin-4A Cullin-4B Cyclin-H Cyclin-dependent kinase 7 DNA damage-binding protein 1 DNA excision repair protein ERCC-6 DNA excision repair protein ERCC-8 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 E3 ubiquitin-protein ligase RBX1 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB General transcription factor IIH subunit 1 General transcription factor IIH subunit 2 General transcription factor IIH subunit 3 General transcription factor IIH subunit 4 General transcription factor IIH subunit 5 Peptidyl-prolyl cis-trans isomerase E Polyubiquitin-B Polyubiquitin-C Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor ISY1 homolog Pre-mRNA-splicing factor SYF1 RNA helicase aquarius RNA polymerase II elongation factor ELL Transcription elongation factor A protein 1 UV-stimulated scaffold protein A Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein 830	O15514 O60306 P0CG47 P0CG48 P18074 P19387 P19388 P19447 P23193 P24928 P30876 P32780 P36954 P50613 P51946 P51948 P52434 P52435 P53803 P55199 P61218 P62487 P62875 P62877 P62979 P62987 Q03468 Q13216 Q13619 Q13620 Q13888 Q13889 Q16531 Q2YD98 Q6ZYL4 Q92759 Q93009 Q96NB3 Q9HCS7 Q9ULR0 Q9UMS4 Q9UNP9	AQR BTF2 BTF2P44 C19orf17 C6orf175 CAK CAK1 CAP35 CCDC16 CCNH CDK7 CDKN7 CKN1 CSA CSB CUL4A CUL4B CYP33 DDB1 ELL ERCC2 ERCC3 ERCC6 ERCC8 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 GTF2S HAUSP HCNP ISY1 KIAA0560 KIAA0695 KIAA1160 KIAA1177 KIAA1530 MAT1 MNAT1 MO15 NMP200 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PPIE PRP19 PRPF19 RBX1 RNF66 RNF75 ROC1 RPB7 RPS27A SNEV STK1 SYF1 TCEA1 TFIIS TTDA UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP7 UVSSA XAB2 XAP1 XPB XPBC XPD XPDC ZNF830
PIWI-interacting RNA (piRNA) biogenesis	ATP-dependent RNA helicase TDRD9 Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Heat shock protein HSP 90-alpha Inactive peptidyl-prolyl cis-trans isomerase FKBP6 Mitochondrial cardiolipin hydrolase Myb-related protein A Piwi-like protein 1 Piwi-like protein 2 Piwi-like protein 4 Probable ATP-dependent RNA helicase DDX4 Protein maelstrom homolog Putative ATP-dependent RNA helicase TDRD12 RNA helicase Mov10l1 Small RNA 2'-O-methyltransferase Tudor and KH domain-containing protein Tudor domain-containing protein 1 Tudor domain-containing protein 6	O15514 O60522 O75344 P07900 P10243 P19387 P19388 P24928 P30876 P36954 P52434 P52435 P53803 P61218 P62487 P62875 Q587J7 Q5T8I9 Q7Z3Z4 Q8N2A8 Q8NDG6 Q8TC59 Q8WWH4 Q96J94 Q96JY0 Q9BXT4 Q9BXT6 Q9NQI0 Q9Y2W6	ALP1 AMYB ANKL1 ASZ1 C14orf75 C1orf59 C7orf7 DDX4 ECAT8 FKBP36 FKBP6 GASZ HENMT1 HILI HIWI HIWI2 HSP90A HSP90AA1 HSPC1 HSPCA MAEL MOV10L1 MYBL1 PIWI PIWIL1 PIWIL2 PIWIL4 PLD6 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RPB7 TDRD1 TDRD12 TDRD2 TDRD6 TDRD9 TDRKH VASA
Inhibition of DNA recombination at telomere	Adrenocortical dysplasia protein homolog DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Death domain-associated protein 6 Histone H2A type 1-B/E Histone H2A type 1-C Histone H2A type 1-D Histone H2A type 1-J Histone H2A type 2-A Histone H2A type 2-C Histone H2A-Bbd type 1 Histone H2A.J Histone H2A.V Histone H2AX Histone H2B type 1-A Histone H2B type 1-B Histone H2B type 1-C/E/F/G/I Histone H2B type 1-D Histone H2B type 1-H Histone H2B type 1-J Histone H2B type 1-K Histone H2B type 1-L Histone H2B type 1-M Histone H2B type 1-N Histone H2B type 1-O Histone H2B type 2-E Histone H2B type 3-B Histone H2B type F-S Histone H3.1t Histone H3.3 Histone H4 Protection of telomeres protein 1 TERF1-interacting nuclear factor 2 Telomeric repeat-binding factor 1 Telomeric repeat-binding factor 2-interacting protein 1 Telomeric repeat-binding factor 2 Transcriptional regulator ATRX	O15514 O60814 P04908 P06899 P0C5Y9 P16104 P19387 P19388 P20671 P23527 P24928 P30876 P33778 P36954 P46100 P52434 P52435 P53803 P54274 P57053 P58876 P61218 P62487 P62805 P62807 P62875 P84243 Q15554 Q16695 Q16777 Q16778 Q6FI13 Q71UI9 Q8N257 Q93077 Q93079 Q96A08 Q96AP0 Q99877 Q99878 Q99879 Q99880 Q9BSI4 Q9BTM1 Q9NUX5 Q9NYB0 Q9UER7	ACD ATRX BING2 DAP6 DAXX DRIP5 H2AB1 H2AC14 H2AC18 H2AC19 H2AC20 H2AC4 H2AC6 H2AC7 H2AC8 H2AFA H2AFB1 H2AFE H2AFG H2AFJ H2AFL H2AFM H2AFO H2AFQ H2AFV H2AFX H2AJ H2AV H2AX H2AZ2 H2BC1 H2BC10 H2BC11 H2BC12 H2BC12L H2BC13 H2BC14 H2BC15 H2BC17 H2BC21 H2BC26 H2BC3 H2BC4 H2BC5 H2BC6 H2BC7 H2BC8 H2BC9 H2BFA H2BFB H2BFC H2BFD H2BFE H2BFF H2BFG H2BFH H2BFJ H2BFK H2BFL H2BFN H2BFQ H2BFR H2BFS H2BFT H2BS1 H2BU1 H3-3A H3-3B H3-4 H3.3A H3.3B H3F3 H3F3A H3F3B H3FT H4-16 H4/A H4/B H4/C H4/D H4/E H4/G H4/H H4/I H4/J H4/K H4/M H4/N H4/O H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C16 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 H4F2 H4FA H4FB H4FC H4FD H4FE H4FG H4FH H4FI H4FJ H4FK H4FM H4FN H4FO HIRIP1 HIRIP2 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AJ HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA HIST2H2AA3 HIST2H2AA4 HIST2H2AC HIST2H2BE HIST2H4 HIST2H4A HIST2H4B HIST3H2BB HIST3H3 HIST4H4 PIN2 PIP1 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF POT1 PTOP RAD54L RAP1 RPB7 TERF1 TERF2 TERF2IP TIN2 TINF2 TINT1 TPP1 TRBF1 TRBF2 TRF TRF1 TRF2 TSH2B XH2
U12 Dependent Splicing	116 kDa U5 small nuclear ribonucleoprotein component ATP-dependent RNA helicase DDX42 DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Pre-mRNA-processing factor 6 Pre-mRNA-processing-splicing factor 8 Probable ATP-dependent RNA helicase DDX23 Programmed cell death protein 7 RNA-binding region-containing protein 3 Serine/arginine-rich splicing factor 1 Serine/arginine-rich splicing factor 2 Serine/arginine-rich splicing factor 6 Serine/arginine-rich splicing factor 7 Small nuclear ribonucleoprotein E Small nuclear ribonucleoprotein F Small nuclear ribonucleoprotein G Small nuclear ribonucleoprotein Sm D1 Small nuclear ribonucleoprotein Sm D2 Small nuclear ribonucleoprotein Sm D3 Small nuclear ribonucleoprotein-associated proteins B and B' Splicing factor 3B subunit 1 Splicing factor 3B subunit 2 Splicing factor 3B subunit 3 Splicing factor 3B subunit 4 Splicing factor 3B subunit 5 Splicing factor 3B subunit 6 Thioredoxin-like protein 4A U11/U12 small nuclear ribonucleoprotein 25 kDa protein U11/U12 small nuclear ribonucleoprotein 35 kDa protein U11/U12 small nuclear ribonucleoprotein 48 kDa protein U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 U5 small nuclear ribonucleoprotein 200 kDa helicase U5 small nuclear ribonucleoprotein 40 kDa protein Y-box-binding protein 1 Zinc finger CCHC-type and RNA-binding motif-containing protein 1 Zinc finger matrin-type protein 5	O15514 O75533 O75643 O94906 P13984 P14678 P19387 P19388 P24928 P30876 P35269 P36954 P52298 P52434 P52435 P53803 P61218 P62304 P62306 P62308 P62314 P62316 P62318 P62487 P62875 P67809 P83876 Q01130 Q07955 Q09161 Q13247 Q13435 Q15029 Q15393 Q15427 Q15696 Q16560 Q16629 Q6IEG0 Q6P2Q9 Q86XP3 Q8N8D1 Q8TBF4 Q96DI7 Q96LT9 Q9BUQ8 Q9BV90 Q9BWJ5 Q9UDW3 Q9Y3B4	ASCC3L1 ASF BRR2 C16orf33 C20orf14 C6orf151 CBP20 CBP80 COD DDX23 DDX42 DIM1 EFTUD2 GTF2F1 GTF2F2 HELIC2 HM1 KIAA0017 KIAA0031 KIAA0788 KIAA1839 NCBP NCBP1 NCBP2 NSEP1 PBSCF PBSCG PDCD7 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PRP8BP PRPC8 PRPF6 PRPF8 RAP30 RAP74 RBM40 RNP RNPC3 RPB7 SAP130 SAP14 SAP145 SAP155 SAP49 SF2 SF2P33 SF3B1 SF3B10 SF3B14 SF3B14A SF3B2 SF3B3 SF3B4 SF3B5 SF3B6 SFP38 SFRS1 SFRS2 SFRS6 SFRS7 SNRNP200 SNRNP25 SNRNP35 SNRNP40 SNRNP48 SNRNP65 SNRP116 SNRPB SNRPB1 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SRP55 SRSF1 SRSF2 SRSF6 SRSF7 TXNL4 TXNL4A U1SNRNPBP U2AF1-RS2 U2AF1L2 U2AF1RS2 URP WDR57 YB1 YBX1 ZCRB1 ZMAT5 ZRSR2
MicroRNA (miRNA) biogenesis	DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Endoribonuclease Dicer Exportin-5 GTP-binding nuclear protein Ran Interferon-inducible double-stranded RNA-dependent protein kinase activator A Microprocessor complex subunit DGCR8 Protein argonaute-1 Protein argonaute-2 Protein argonaute-3 Protein argonaute-4 RISC-loading complex subunit TARBP2 RNA 5'-monophosphate methyltransferase Ribonuclease 3	O15514 O75569 P19387 P19388 P24928 P30876 P36954 P52434 P52435 P53803 P61218 P62487 P62826 P62875 Q15633 Q7Z5W3 Q8WYQ5 Q9H9G7 Q9HAV4 Q9HCK5 Q9NRR4 Q9UKV8 Q9UL18 Q9UPY3	AGO1 AGO2 AGO3 AGO4 ARA24 BCDIN3D C22orf12 DGCR8 DGCRK6 DICER DICER1 DROSHA EIF2C1 EIF2C2 EIF2C3 EIF2C4 HERNA KIAA0928 KIAA1291 KIAA1567 PACT POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF PRKRA RAN RANBP21 RAX RN3 RNASE3L RNASEN RPB7 TARBP2 TRBP XPO5
Signaling by FGFR2 IIIa TM	DNA-directed RNA polymerase II subunit RPB11-a DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 2 General transcription factor IIF subunit 1 General transcription factor IIF subunit 2 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2	O15514 P05230 P09038 P13984 P19387 P19388 P21802 P24928 P30876 P35269 P36954 P52298 P52434 P52435 P53803 P61218 P62487 P62875 Q09161	BEK CBP20 CBP80 FGF1 FGF2 FGFA FGFB FGFR2 GTF2F1 GTF2F2 KGFR KSAM NCBP NCBP1 NCBP2 POLR2 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J1 POLR2K POLR2L POLRF RAP30 RAP74 RPB7
Downstream signaling of activated FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Leucine-rich repeat transmembrane protein FLRT1 Leucine-rich repeat transmembrane protein FLRT2 Leucine-rich repeat transmembrane protein FLRT3	O15520 O43155 P05230 P08620 P09038 P10767 P11487 P31371 Q9GZV9 Q9HCT0 Q9NP95 Q9NZU0 Q9NZU1	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB FLRT1 FLRT2 FLRT3 HST HST2 HSTF1 HSTF2 HYPF INT2 KIAA0405 KIAA1469 KS3
FRS-mediated FGFR2 signaling	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O15520 O43320 O43559 O76093 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P21781 P31371 Q06124 Q07889 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1
Signaling by FGFR2 in disease	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 GTPase HRas GTPase NRas Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Son of sevenless homolog 1	O15520 O43320 O76093 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P19174 P21781 P21802 P27986 P31371 P42336 Q07889 Q13480 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	BEK FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FGFR2 FRS2 GAB1 GRB1 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KGFR KS3 KSAM NRAS PIK3CA PIK3R1 PLC1 PLCG1 SOS1
SHC-mediated cascade:FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 GTPase HRas GTPase NRas Son of sevenless homolog 1	O15520 O43320 O76093 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P21781 P31371 Q07889 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 NRAS SOS1
Negative regulation of FGFR2 signaling	E3 ubiquitin-protein ligase CBL Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15520 O43320 O76093 P05230 P08620 P09038 P0CG47 P0CG48 P10767 P11487 P21781 P22681 P27361 P28482 P31371 P62979 P62987 Q06124 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	CBL CBL2 ERK1 ERK2 FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FRS2 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9	O15520 O43320 O76093 P05230 P08620 P09038 P10767 P11487 P19174 P21781 P31371 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 PLC1 PLCG1
Activated point mutants of FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor 2	O15520 O43320 O76093 P05230 P08620 P09038 P10767 P11487 P21781 P21802 P31371 Q9GZV9 Q9HCT0 Q9NP95	BEK FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FGFR2 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KGFR KS3 KSAM
PI-3K cascade:FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 16 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 7 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 GRB2-associated-binding protein 1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type 11	O15520 O43320 O76093 P05230 P08620 P09038 P10767 P11487 P21781 P27986 P31371 P42336 Q06124 Q13480 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF16 FGF18 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF7 FGF9 FGFA FGFB FRS2 GAB1 GRB1 HST HST2 HSTF1 HSTF2 HYPF INT2 KGF KS3 PIK3CA PIK3R1 PTP2C PTPN11 SHPTP2
FRS-mediated FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 GTPase HRas GTPase NRas Son of sevenless homolog 1 Tyrosine-protein phosphatase non-receptor type 11	O15520 O43559 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P31371 Q06124 Q07889 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB FRS2 FRS3 HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KS3 NRAS PTP2C PTPN11 SHPTP2 SOS1
Regulation of gene expression in early pancreatic precursor cells	Fibroblast growth factor 10 Hepatocyte nuclear factor 1-beta Hepatocyte nuclear factor 6 Homeobox protein Nkx-6.1 One cut domain family member 3 Pancreas transcription factor 1 subunit alpha Pancreas/duodenum homeobox protein 1	O15520 O60422 P35680 P52945 P78426 Q7RTS3 Q9UBC0	BHLHA29 FGF10 HNF1B HNF6 HNF6A IPF1 NKX6-1 NKX6A ONECUT1 ONECUT3 PDX1 PTF1A PTF1P48 STF1 TCF2
FGFRL1 modulation of FGFR1 signaling	Fibroblast growth factor 10 Fibroblast growth factor 18 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor receptor-like 1 Sprouty-related, EVH1 domain-containing protein 1 Sprouty-related, EVH1 domain-containing protein 2	O15520 O76093 P08620 P09038 P11487 Q7Z698 Q7Z699 Q8N441 Q9GZV9 Q9HCT0	FGF10 FGF18 FGF2 FGF22 FGF23 FGF3 FGF4 FGFB FGFR5 FGFRL1 FHFR HST HSTF1 HYPF INT2 KS3 SPRED1 SPRED2
SHC-mediated cascade:FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 GTPase HRas GTPase NRas Son of sevenless homolog 1	O15520 P01111 P01112 P05230 P08620 P09038 P10767 P11487 P31371 Q07889 Q9GZV9 Q9HCT0 Q9NP95	FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB HRAS HRAS1 HST HST2 HSTF1 HSTF2 HYPF INT2 KS3 NRAS SOS1
Negative regulation of FGFR1 signaling	Anosmin-1 E3 ubiquitin-protein ligase CBL Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 22 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor 4 Fibroblast growth factor 6 Fibroblast growth factor 9 Fibroblast growth factor receptor substrate 2 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Polyubiquitin-B Polyubiquitin-C Tyrosine-protein phosphatase non-receptor type 11 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	O15520 P05230 P08620 P09038 P0CG47 P0CG48 P10767 P11487 P22681 P23352 P27361 P28482 P31371 P62979 P62987 Q06124 Q8WU20 Q9GZV9 Q9HCT0 Q9NP95	ADMLX ANOS1 CBL CBL2 ERK1 ERK2 FGF1 FGF10 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF6 FGF9 FGFA FGFB FRS2 HST HST2 HSTF1 HSTF2 HYPF INT2 KAL KAL1 KALIG1 KS3 MAPK1 MAPK3 PRKM1 PRKM2 PRKM3 PTP2C PTPN11 RNF55 RPS27A SHPTP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2

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