Sodium/Proton exchangers
|
|
|
- APNH1
- KIAA0267
- KIAA0939
- NHE1
- NHE2
- NHE3
- NHE4
- NHE5
- NHE6
- NHE7
- NHE8
- NHE9
- SLC9A1
- SLC9A2
- SLC9A3
- SLC9A4
- SLC9A5
- SLC9A6
- SLC9A7
- SLC9A8
- SLC9A9
|
|
Ligand-dependent caspase activation
|
|
|
- APO2
- APO2L
- APT1
- APT1LG1
- CASP8
- CD14
- CD95L
- DR4
- DR5
- ESOP1
- FADD
- FAS
- FAS1
- FASL
- FASLG
- KILLER
- LY96
- MC159L
- MCH5
- MD2
- MORT1
- ORF71
- PRVTIRB
- RIP
- RIP1
- RIPK1
- TICAM1
- TICAM2
- TIRAP3
- TIRP
- TLR4
- TNFRSF10A
- TNFRSF10B
- TNFRSF6
- TNFSF10
- TNFSF6
- TRADD
- TRAF2
- TRAIL
- TRAILR1
- TRAILR2
- TRAM
- TRAP3
- TRICK2
- TRIF
- ZTNFR9
|
|
CASP8 activity is inhibited
|
|
|
- APO2
- APO2L
- APT1
- APT1LG1
- CASP8
- CD95L
- DR4
- DR5
- FADD
- FAS
- FAS1
- FASL
- FASLG
- KILLER
- MCH5
- MORT1
- RIP
- RIP1
- RIPK1
- TNFRSF10A
- TNFRSF10B
- TNFRSF6
- TNFSF10
- TNFSF6
- TRADD
- TRAF2
- TRAIL
- TRAILR1
- TRAILR2
- TRAP3
- TRICK2
- ZTNFR9
|
|
Regulation by c-FLIP
|
|
|
- APO2
- APO2L
- APT1
- APT1LG1
- CASP8
- CD95L
- DR4
- DR5
- FADD
- FAS
- FAS1
- FASL
- FASLG
- KILLER
- MCH5
- MORT1
- RIP
- RIP1
- RIPK1
- TNFRSF10A
- TNFRSF10B
- TNFRSF6
- TNFSF10
- TNFSF6
- TRADD
- TRAF2
- TRAIL
- TRAILR1
- TRAILR2
- TRAP3
- TRICK2
- ZTNFR9
|
|
Dimerization of procaspase-8
|
|
|
- APO2
- APO2L
- APT1
- APT1LG1
- CASP8
- CD95L
- DR4
- DR5
- FADD
- FAS
- FAS1
- FASL
- FASLG
- KILLER
- MCH5
- MORT1
- RIP
- RIP1
- RIPK1
- TNFRSF10A
- TNFRSF10B
- TNFRSF6
- TNFSF10
- TNFSF6
- TRADD
- TRAF2
- TRAIL
- TRAILR1
- TRAILR2
- TRAP3
- TRICK2
- ZTNFR9
|
|
TRAIL signaling
|
|
|
- APO2
- APO2L
- CASH
- CASP10
- CASP8
- CASP8AP1
- CFLAR
- CLARP
- DCR2
- DR4
- DR5
- FADD
- KILLER
- MCH4
- MCH5
- MORT1
- MRIT
- TNFRSF10A
- TNFRSF10B
- TNFRSF10D
- TNFSF10
- TRAIL
- TRAILR1
- TRAILR2
- TRAILR4
- TRICK2
- TRUNDD
- ZTNFR9
|
|
TP53 Regulates Transcription of Death Receptors and Ligands
|
|
|
- APO2
- APT1
- ASPP1
- ASPP2
- BBP
- DCR1
- DCR2
- DR4
- DR5
- FAS
- FAS1
- IBP3
- IGFBP3
- KET
- KIAA0771
- KILLER
- LIT
- P53
- P63
- P73
- P73H
- P73L
- PPP1R13B
- TMEM219
- TNFRSF10A
- TNFRSF10B
- TNFRSF10C
- TNFRSF10D
- TNFRSF6
- TP53
- TP53BP2
- TP63
- TP73
- TP73L
- TRAILR1
- TRAILR2
- TRAILR3
- TRAILR4
- TRICK2
- TRID
- TRUNDD
- ZTNFR9
|
|
Scavenging by Class A Receptors
|
|
|
- APOA1
- APOB
- APOE
- CALR
- CLP1
- COL1A1
- COL1A2
- COL3A1
- COL4A1
- COL4A2
- COLEC11
- COLEC12
- CRARF
- CRARF1
- CRTC
- FTH
- FTH1
- FTHL6
- FTL
- GRP94
- HSP90B1
- HSPC4
- MARCO
- MASP1
- MSR1
- NSR2
- PNSP1
- PRSS5
- SCARA1
- SCARA2
- SCARA4
- SCARA5
- SCGB3A2
- SRCL
- TRA1
- UGRP1
|
|
Scavenging by Class B Receptors
|
|
|
- APOA1
- APOB
- CD36
- GP3B
- GP4
- SAA1
- SSC5D
|
|
VLDL clearance
|
|
|
- APOB
- APOB48R
- APOBR
- APOC1
- APOC4
- ILDR3
- LISCH
- LSR
- VLDLR
|
|
VLDL assembly
|
|
|
- APOB
- APOC1
- APOC4
- ERBA2L
- MTP
- MTTP
- P4HB
- PDI
- PDIA1
- PO4DB
|
|
Chylomicron clearance
|
|
|
- APOB
- APOE
- ARH
- HTGL
- LDLR
- LDLRAP1
- LIPC
|
|
Platelet sensitization by LDL
|
|
|
- APOB
- APOER2
- CPLA2
- CSBP
- CSBP1
- CSBP2
- CSPB1
- FGR
- HCP
- KIAA0044
- LRP8
- MAPK14
- MXI2
- PECAM1
- PLA2G4
- PLA2G4A
- PPP2CA
- PPP2CB
- PPP2R1A
- PPP2R1B
- PPP2R5A
- PPP2R5B
- PPP2R5C
- PPP2R5D
- PPP2R5E
- PTP1C
- PTP2C
- PTPN11
- PTPN6
- SAPK2A
- SHPTP2
- SRC2
|
|
LDL remodeling
|
|
|
- APOB
- APOF
- CETP
- ERBA2L
- LPA
- MTP
- MTTP
- P4HB
- PDI
- PDIA1
- PO4DB
|
|
Regulation of TLR by endogenous ligand
|
|
|
- APOB
- CAGA
- CAGB
- CD14
- CD36
- CFAG
- DFNA5
- DFNA5L
- ESOP1
- FGA
- FGB
- FGG
- GP3B
- GP4
- GSDMD
- GSDMDC1
- GSDME
- HMG1
- HMGB1
- ICERE1
- KIAA0012
- LBP
- LY96
- MD2
- MRP14
- MRP8
- S100A
- S100A1
- S100A8
- S100A9
- TIL4
- TLR1
- TLR2
- TLR4
- TLR6
- TLR7
|
|
Scavenging by Class F Receptors
|
|
|
- APOB
- CALR
- CRTC
- GRP170
- HSP105
- HSP110
- HSP90A
- HSP90AA1
- HSPC1
- HSPCA
- HSPH1
- HSPH4
- HYOU1
- KIAA0149
- KIAA0201
- ORP150
- SCARF1
- SREC
- porB
|
|
Scavenging by Class H Receptors
|
|
|
- APOB
- FEEL1
- FEEL2
- FELL
- FEX2
- HARE
- KIAA0246
- ON
- SPARC
- STAB1
- STAB2
|
|
Terminal pathway of complement
|
|
|
- APOJ
- C5
- C6
- C7
- C8A
- C8B
- C8G
- C9
- CLI
- CLU
- CPAMD4
- KUB1
|
|
Resolution of D-loop Structures through Holliday Junction Intermediates
|
|
|
- APOLO1
- ATM
- BACH1
- BARD1
- BLM
- BRCA1
- BRCA2
- BRIP1
- BTBD12
- C16orf75
- C1orf112
- C7orf76
- C9orf76
- CTIP
- DNA2
- DNA2L
- DSS1
- EME1
- EME2
- EXO1
- EXOI
- FACD
- FANCD1
- FANCJ
- FANCN
- FIGNL1
- FIRRM
- GEN1
- GIYD1
- GIYD2
- HEX1
- HNGS1
- HTATIP
- KAT5
- KIAA0083
- KIAA0146
- KIAA1784
- KIAA1987
- MMS4
- MRE11
- MRE11A
- MUS81
- NBN
- NBS
- NBS1
- P95
- PALB2
- PIR51
- RAD50
- RAD51
- RAD51A
- RAD51AP1
- RAD51B
- RAD51C
- RAD51D
- RAD51L1
- RAD51L2
- RAD51L3
- RBBP8
- REC2
- RECA
- RECQ2
- RECQ3
- RECQL2
- RECQL3
- RMI1
- RMI2
- RNF53
- SEM1
- SHFDG1
- SHFM1
- SLX1
- SLX1A
- SLX1B
- SLX4
- SPIDR
- TIP60
- TOP3
- TOP3A
- WRN
- XRCC2
- XRCC3
|
|
Cristae formation
|
- ATP synthase F(0) complex subunit B1, mitochondrial
- ATP synthase F(0) complex subunit C1, mitochondrial
- ATP synthase F(0) complex subunit C2, mitochondrial
- ATP synthase F(0) complex subunit C3, mitochondrial
- ATP synthase protein 8
- ATP synthase subunit O, mitochondrial
- ATP synthase subunit a
- ATP synthase subunit alpha, mitochondrial
- ATP synthase subunit beta, mitochondrial
- ATP synthase subunit d, mitochondrial
- ATP synthase subunit delta, mitochondrial
- ATP synthase subunit e, mitochondrial
- ATP synthase subunit epsilon, mitochondrial
- ATP synthase subunit f, mitochondrial
- ATP synthase subunit g, mitochondrial
- ATP synthase subunit gamma, mitochondrial
- ATP synthase subunit s, mitochondrial
- ATP synthase-coupling factor 6, mitochondrial
- DnaJ homolog subfamily C member 11
- MICOS complex subunit MIC10
- MICOS complex subunit MIC13
- MICOS complex subunit MIC19
- MICOS complex subunit MIC25
- MICOS complex subunit MIC26
- MICOS complex subunit MIC27
- MICOS complex subunit MIC60
- Metaxin-1
- Metaxin-2
- Sorting and assembly machinery component 50 homolog
- Stress-70 protein, mitochondrial
- Transmembrane protein 11, mitochondrial
|
|
- APOO
- APOOL
- ATP5A
- ATP5A1
- ATP5AL2
- ATP5B
- ATP5C
- ATP5C1
- ATP5CL1
- ATP5D
- ATP5E
- ATP5F1
- ATP5F1A
- ATP5F1B
- ATP5F1C
- ATP5F1D
- ATP5F1E
- ATP5G1
- ATP5G2
- ATP5G3
- ATP5H
- ATP5I
- ATP5J
- ATP5J2
- ATP5JL
- ATP5K
- ATP5L
- ATP5MC1
- ATP5MC2
- ATP5MC3
- ATP5ME
- ATP5MF
- ATP5MG
- ATP5O
- ATP5PB
- ATP5PD
- ATP5PF
- ATP5PO
- ATP5S
- ATP6
- ATP8
- ATPASE6
- ATPASE8
- ATPM
- ATPMB
- ATPO
- ATPSB
- ATPW
- C17orf35
- C19orf70
- C1orf151
- CHCHD3
- CHCHD6
- CHCM1
- CXorf33
- DMAC2L
- DNAJC11
- FAM121A
- FAM121B
- GRP75
- HMP
- HSPA9
- HSPA9B
- IMMT
- MIC10
- MIC13
- MIC19
- MIC23
- MIC25
- MIC26
- MIC27
- MIC60
- MICOS10
- MICOS13
- MINOS1
- MINOS2
- MINOS3
- MT-ATP6
- MT-ATP8
- MTATP6
- MTATP8
- MTX
- MTX1
- MTX2
- MTXN
- PM1
- QIL1
- SAM50
- SAMM50
- TMEM11
- mt-HSP70
|
|
Ligand-independent caspase activation via DCC
|
|
|
- APPL
- APPL1
- CASP3
- CASP9
- CPP32
- DAPK
- DAPK1
- DAPK2
- DAPK3
- DCC
- DIP13A
- IGDCC1
- KIAA1428
- KIAA1976
- MAGED1
- MCH6
- NRAGE
- P53RDL1
- UNC5A
- UNC5B
- UNC5H1
- UNC5H2
- ZIPK
|
|
Signaling by CSF3 (G-CSF)
|
|
|
- APRF
- ASH
- C17orf33
- CIS3
- CSF3
- CSF3R
- GAB2
- GCSF
- GCSFR
- GRB2
- HCK
- JAK1
- JAK1A
- JAK1B
- JAK2
- JTK8
- KIAA0571
- KRAS
- KRAS2
- LYN
- PTP2C
- PTPN11
- RASK2
- SHC
- SHC1
- SHCA
- SHPTP2
- SOCS1
- SOCS3
- SSI1
- SSI3
- STAT1
- STAT3
- STAT5
- STAT5A
- STAT5B
- SYK
- TIP3
- TYK2
|
|
Interleukin-15 signaling
|
|
|
- APRF
- ASH
- GAB2
- GRB2
- IL15
- IL15RA
- IL15RB
- IL2RB
- IL2RG
- JAK1
- JAK1A
- JAK1B
- JAK3
- KIAA0571
- SHC
- SHC1
- SHCA
- SOS1
- SOS2
- STAT3
- STAT5
- STAT5A
- STAT5B
|
|
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
|
|
|
- APRF
- BAD
- BBC3
- BBC6
- BCL2
- BCL2L
- BCL2L1
- BCL2L11
- BCL2L8
- BCLX
- BID
- BIM
- BMF
- NOXA
- PMAIP1
- PUMA
- STAT3
|
|
Interleukin-7 signaling
|
|
|
- APRF
- BAF190A
- BRG1
- BRWD1
- C21orf107
- CIS2
- CISH
- CRL2
- CRLF2
- G18
- GRB1
- H3C1
- H3C10
- H3C11
- H3C12
- H3C13
- H3C14
- H3C15
- H3C2
- H3C3
- H3C4
- H3C6
- H3C7
- H3C8
- H3F2
- H3FA
- H3FB
- H3FC HIST1H3C
- H3FD
- H3FF
- H3FH
- H3FI
- H3FJ
- H3FK
- H3FL
- H3FM
- HGF
- HIST1H3A
- HIST1H3B
- HIST1H3D
- HIST1H3E
- HIST1H3F
- HIST1H3G
- HIST1H3H
- HIST1H3I
- HIST1H3J
- HIST2H3A
- HIST2H3C
- HIST2H3D
- HPTA
- IL2RG
- IL7
- IL7R
- ILXR
- IRS1
- IRS2
- JAK1
- JAK1A
- JAK1B
- JAK3
- PIK3R1
- PIK3R2
- PIK3R3
- RAG1
- RAG2
- RNF74
- SMARCA4
- SNF2B
- SNF2L4
- SOCS1
- SOCS2
- SSI1
- SSI2
- STAT3
- STAT5
- STAT5A
- STAT5B
- STATI2
- TIP3
- TSLP
- TSLPR
- WDR9
|
|