Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP)
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Cholesterol biosynthesis
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- 17HSD7
- ACAT2
- ACTL
- ANG1
- ARV1
- BHLHD1
- BHLHD2
- CYP51
- CYP51A1
- DESP4
- DHCR24
- ERG1
- ERG25
- FDFT1
- FDPS
- FPS
- GGPS1
- H105E3
- HMGCS
- HMGCS1
- HSD17B7
- IDI1
- IDI2
- KIAA0018
- KIAA1293
- LBR
- LSS
- MPD
- MSMO1
- MVD
- MVK
- NSDHL
- OSC
- PDP1
- PLPP6
- PMKI
- PMVK
- PPAPDC2
- SC4MOL
- SDR37C1
- SQLE
- SREBF1
- SREBF2
- SREBP1
- SREBP2
- TM7SF2
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Iron uptake and transport
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- ABCG2
- ABCP
- ACO1
- BCRP
- BCRP1
- BOCT
- BOIT
- CAND1
- CP
- CUL1
- CYBRD1
- DCT1
- DCYTB
- DMT1
- EMC19
- FBL4
- FBL5
- FBXL5
- FLR1
- FPN
- FPN1
- FRRS3
- FTH
- FTH1
- FTHL6
- FTL
- FTMT
- G21
- GLRX3
- HCP1
- HEPH
- HMOX1
- HMOX2
- HNL
- HO
- HO1
- HO2
- IREB1
- IREB2
- IREG1
- KIAA0698
- KIAA0829
- LCN2
- MXR
- NEDD8
- NGAL
- NRAMP2
- OCP2
- PCFT
- PICOT
- RPS27A
- SKP1
- SKP1A
- SLC11A2
- SLC11A3
- SLC22A17
- SLC40A1
- SLC46A1
- TCEB1L
- TF
- TIP120
- TIP120A
- TXNL2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
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Formation of ATP by chemiosmotic coupling
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- ATP synthase F(0) complex subunit B1, mitochondrial
- ATP synthase F(0) complex subunit C1, mitochondrial
- ATP synthase F(0) complex subunit C2, mitochondrial
- ATP synthase F(0) complex subunit C3, mitochondrial
- ATP synthase protein 8
- ATP synthase subunit O, mitochondrial
- ATP synthase subunit a
- ATP synthase subunit alpha, mitochondrial
- ATP synthase subunit beta, mitochondrial
- ATP synthase subunit d, mitochondrial
- ATP synthase subunit delta, mitochondrial
- ATP synthase subunit e, mitochondrial
- ATP synthase subunit epsilon, mitochondrial
- ATP synthase subunit f, mitochondrial
- ATP synthase subunit g, mitochondrial
- ATP synthase subunit gamma, mitochondrial
- ATP synthase subunit s, mitochondrial
- ATP synthase-coupling factor 6, mitochondrial
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- ATP5A
- ATP5A1
- ATP5AL2
- ATP5B
- ATP5C
- ATP5C1
- ATP5CL1
- ATP5D
- ATP5E
- ATP5F1
- ATP5F1A
- ATP5F1B
- ATP5F1C
- ATP5F1D
- ATP5F1E
- ATP5G1
- ATP5G2
- ATP5G3
- ATP5H
- ATP5I
- ATP5J
- ATP5J2
- ATP5JL
- ATP5K
- ATP5L
- ATP5MC1
- ATP5MC2
- ATP5MC3
- ATP5ME
- ATP5MF
- ATP5MG
- ATP5O
- ATP5PB
- ATP5PD
- ATP5PF
- ATP5PO
- ATP5S
- ATP6
- ATP8
- ATPASE6
- ATPASE8
- ATPM
- ATPMB
- ATPO
- ATPSB
- ATPW
- DMAC2L
- MT-ATP6
- MT-ATP8
- MTATP6
- MTATP8
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Carnitine synthesis
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- ALDH4
- ALDH7
- ALDH9
- ALDH9A1
- BBH
- BBOX
- BBOX1
- SHMT1
- TMLH
- TMLHE
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Formation of Incision Complex in GG-NER
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- ADPRT
- ADPRT2
- ADPRTL2
- ALC1
- BLU
- BTF2
- BTF2P44
- C6orf175
- CAK
- CAK1
- CALT
- CAP35
- CCNH
- CDK7
- CDKN7
- CEN2
- CETN2
- CHD1L
- CUL4A
- CUL4B
- DDB1
- DDB2
- DDXBP1
- ERCC1
- ERCC11
- ERCC2
- ERCC3
- ERCC4
- ERCC5
- ERCM2
- GTF2H1
- GTF2H2
- GTF2H3
- GTF2H4
- GTF2H5
- KIAA0695
- MAT1
- MMS2
- MNAT1
- MO15
- PARP1
- PARP2
- PIAS1
- PIAS3
- PPOL
- RAD23A
- RAD23B
- RBX1
- REPA1
- REPA2
- REPA3
- RNF111
- RNF66
- RNF75
- ROC1
- RPA1
- RPA14
- RPA2
- RPA3
- RPA32
- RPA34
- RPA70
- RPS27A
- SMT3A
- SMT3B
- SMT3C
- SMT3H1
- SMT3H2
- SMT3H3
- STK1
- SUMO1
- SUMO2
- SUMO3
- TTDA
- UBA52
- UBA80
- UBB
- UBC
- UBC9
- UBCE9
- UBCEP1
- UBCEP2
- UBE2I
- UBE2N
- UBE2V2
- UBL1
- UEV2
- USP45
- XAP1
- XPA
- XPAC
- XPB
- XPBC
- XPC
- XPCC
- XPD
- XPDC
- XPF
- XPG
- XPGC
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SUMOylation of intracellular receptors
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- AD4BP
- AR
- DDXBP1
- DHTR
- ERBA2
- ESR
- ESR1
- FTZF1
- GRL
- HDAC4
- KIAA0288
- LXRB
- MCR
- MLR
- NER
- NOT
- NR1A2
- NR1B1
- NR1C1
- NR1C3
- NR1F1
- NR1H2
- NR1I1
- NR2B1
- NR2C1
- NR3A1
- NR3C1
- NR3C2
- NR3C3
- NR3C4
- NR4A2
- NR5A1
- NURR1
- PGR
- PIAS1
- PIAS3
- PIAS4
- PIASG
- PPAR
- PPARA
- PPARG
- RARA
- RORA
- RXRA
- RZRA
- SF1
- SMT3A
- SMT3B
- SMT3C
- SMT3H1
- SMT3H2
- SMT3H3
- SUMO1
- SUMO2
- SUMO3
- THR1
- THRB
- TINUR
- TR2
- UBC9
- UBCE9
- UBE2I
- UBL1
- UNR
- VDR
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CD28 dependent Vav1 pathway
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- CD28
- CD28LG
- CD28LG1
- CD28LG2
- CD80
- CD86
- CDC42
- FYN
- LAB7
- LCK
- OPHN3
- PAK1
- PAK2
- PAK3
- RAC1
- TC25
- VAV
- VAV1
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Effects of PIP2 hydrolysis
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- CDC25L
- DAGK
- DAGK1
- DAGK2
- DAGK3
- DAGK4
- DAGK5
- DAGK6
- DGKA
- DGKB
- DGKD
- DGKE
- DGKG
- DGKH
- DGKI
- DGKK
- DGKQ
- DGKZ
- INSP3R1
- ITPR1
- ITPR2
- ITPR3
- KIAA0145
- KIAA0718
- MCG7
- PKCD
- PKCE
- PKCL
- PRKCD
- PRKCE
- PRKCH
- PRKCL
- PRKCQ
- PRKCT
- RASGRP
- RASGRP1
- RASGRP2
- TRP3
- TRP6
- TRP7
- TRPC3
- TRPC6
- TRPC7
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The retinoid cycle in cones (daylight vision)
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- AWAT2
- BCP
- CRALBP
- DC4
- DGAT2L4
- DHRS3
- GCP
- MFAT
- OPN1LW
- OPN1MW
- OPN1SW
- RBP3
- RCP
- RDH17
- RLBP1
- SDR16C1
- WS
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Acyl chain remodeling of DAG and TAG
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- ADPN
- AGRP1
- ATGL
- AWAT2
- C22orf20
- DC3
- DC4
- DGAT
- DGAT1
- DGAT2
- DGAT2L4
- DGAT2L6
- MFAT
- MGLL
- PNPLA2
- PNPLA3
- WS
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Triglyceride biosynthesis
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- AGMO
- AGRP1
- DC2
- DC5
- DC7
- DGAT
- DGAT1
- DGAT2
- DGAT2L1
- DGAT2L5
- DGAT2L7
- GK
- GK2
- GK3
- GK3P
- GKP2
- GKP3
- GKTA
- GKTB
- GPAM
- GPAT1
- GPAT2
- KIAA0188
- KIAA0249
- KIAA1560
- LIPN3L
- LPIN1
- LPIN2
- LPIN3
- MOGAT1
- MOGAT2
- MOGAT3
- TMEM195
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GABA B receptor activation
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- GABBR1
- GABBR2
- GPR51
- GPRC3A
- GPRC3B
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Metabolism of folate and pterines
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- ALDH1L1
- ALDH1L2
- DHFR
- DHFR2
- DHFRL1
- DHFRP4
- FLOT1
- FOLR2
- FTHFD
- FTHFSDC1
- G21
- HCP1
- MFT
- MFTC
- MTHFC
- MTHFD
- MTHFD1
- MTHFD1L
- MTHFD2
- MTHFD2L
- MTHFR
- MTHFS
- NMDMC
- PCFT
- RFC1
- SHMT1
- SHMT2
- SLC19A1
- SLC25A32
- SLC46A1
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Synthesis of bile acids and bile salts via 27-hydroxycholesterol
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- AKR1C1
- AKR1C2
- AKR1C3
- AKR1C4
- AKR1D1
- BAR
- BHLHE74
- BHLHE75
- CHDR
- CYP12
- CYP27
- CYP27A1
- CYP7
- CYP7A1
- CYP7B1
- CYP8
- CYP8A1
- CYP8B1
- DDH
- DDH1
- DDH2
- FXR
- HRR1
- HSD17B5
- HSD3B7
- KIAA0119
- NCOA1
- NCOA2
- NR1H4
- NR2B1
- PGFS
- PTGIS
- RIP14
- RXRA
- SRC1
- SRC2
- SRD5B1
- TIF2
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Synthesis of bile acids and bile salts
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- BAR
- BHLHE74
- BHLHE75
- CH25H
- CYP7
- CYP7A1
- CYP7B1
- FXR
- HRR1
- KIAA0704
- KIAA0772
- NCOA1
- NCOA2
- NR1H4
- NR2B1
- ORP1
- ORP2
- ORP3
- ORP6
- ORP7
- ORP9
- OSBP
- OSBP1
- OSBP3
- OSBP4
- OSBP8
- OSBPL1
- OSBPL1A
- OSBPL1B
- OSBPL2
- OSBPL3
- OSBPL6
- OSBPL7
- OSBPL9
- RIP14
- RXRA
- SRC1
- SRC2
- TIF2
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Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate
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NFE2L2 regulating TCA cycle genes
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- IDH1
- ME1
- NFE2L2
- NRF2
- PICD
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NADPH regeneration
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Kandutsch-Russell pathway
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- D7SR
- DHCR24
- DHCR7
- EBP
- KIAA0018
- SC5D
- SC5DL
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Bloch pathway
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- D7SR
- DHCR24
- DHCR7
- EBP
- KIAA0018
- SC5D
- SC5DL
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Response of EIF2AK1 (HRI) to heme deficiency
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- ASNS
- ATF3
- ATF4
- ATF5
- ATFX
- BOTCH
- C20orf97
- CEBPB
- CEBPG
- CHAC1
- CHOP
- CHOP10
- CREB2
- DDIT3
- EIF2A
- EIF2AK1
- EIF2B
- EIF2G
- EIF2S1
- EIF2S2
- EIF2S3
- GADD153
- GADD34
- GRB10
- GRBIR
- HRI
- KIAA0207
- KIAA1369
- NIPK
- PPP1R15A
- SKIP3
- TCF5
- TRB3
- TRIB3
- TS11
- TXREB
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Prednisone ADME
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- ABCB1
- AKR1C1
- ALB
- CBG
- CYP3A3
- CYP3A4
- DDH
- DDH1
- GNT1
- HSD11
- HSD11B1
- HSD11B2
- HSD11K
- HSD11L
- MDR1
- PGY1
- SDR26C1
- SDR9C3
- SERPINA6
- UGT1
- UGT1A3
- UGT2B17
- UGT2B7
- UGTB2B9
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CD28 co-stimulation
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- CD28
- CD28LG
- CD28LG1
- CD28LG2
- CD80
- CD86
- FYN
- GADS
- GRAP2
- GRB2L
- GRID
- JTK8
- LAB7
- LCK
- LYN
- YES
- YES1
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Metabolism of Angiotensinogen to Angiotensins
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- ACE
- ACE2
- AGT
- ANPEP
- APN
- ATP6AP2
- ATP6IP2
- CAPER
- CD13
- CES1
- CES2
- CGL2
- CMA1
- CPA3
- CPB
- CPB1
- CPB2
- CPSD
- CTSD
- CTSG
- CTSGL2
- CTSZ
- CYH
- CYM
- DCP
- DCP1
- ELDF10
- ENPEP
- EPN
- GZMH
- MME
- PCPB
- PEPN
- REN
- SERPINA8
- SES1
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