Signaling by LTK in cancer
|
|
|
- CLIP1
- CYLN1
- ERK1
- ERK2
- GRB1
- MAPK1
- MAPK3
- PIK3C1
- PIK3CA
- PIK3CB
- PIK3R1
- PIK3R2
- PRKM1
- PRKM2
- PRKM3
- RSN
|
|
Interleukin-27 signaling
|
|
|
- APRF
- CANX
- CRL1
- CRLF1
- EBI3
- IL27
- IL27A
- IL27B
- IL27RA
- IL30
- IL6ST
- JAK1
- JAK1A
- JAK1B
- JAK2
- STAT1
- STAT3
- TCCR
- TYK2
- WSX1
|
|
Post-translational protein phosphorylation
|
|
|
- A4
- AAT
- AD1
- ADAM10
- AFP
- AHSG
- ALB
- AMBN
- AMELX
- AMG
- AMGX
- AMTN
- ANO8
- APLP2
- APOA1
- APOA2
- APOA5
- APOB
- APOE
- APOL
- APOL1
- APP
- APPL2
- AT3
- ATGL
- AXLLG
- BDK
- BMP15
- BMP2B
- BMP4
- BNSP
- BPIFB2
- BPIL1
- C20orf184
- C3
- C4A
- C9orf155
- CALU
- CCN1
- CDH2
- CDHN
- CG1
- CHGB
- CHGC
- CHRDL1
- CKAP4
- CLGI
- CO4
- CP
- CPAMD1
- CPAMD2
- CSF1
- CSPG2
- CST3
- CYR61
- DMP1
- DMP4
- DNAJC3
- DVR4
- ENAM
- ERBA2L
- ERP5
- EVA1A
- F5
- FAM176A
- FAM20A
- FAM20C
- FBN
- FBN1
- FETUA
- FGA
- FGF23
- FGG
- FLRG
- FN
- FN1
- FRP
- FSTL1
- FSTL3
- FUCA2
- G19P1
- GAS6
- GDF9B
- GIG1
- GOLM1
- GOLPH2
- GPC3
- GRP94
- HCF2
- HCP
- HPAFP
- HRC
- HSP90B1
- HSPA5BP1
- HSPC4
- HSPG1
- HXB
- HYPF
- IBP1
- IBP3
- IBP4
- IBP5
- IFNB2
- IGFBP1
- IGFBP10
- IGFBP3
- IGFBP4
- IGFBP5
- IGFBP7
- IGHEP2
- IL6
- ITIH2
- KIAA0004
- KIAA0091
- KIAA0268
- KIAA1583
- KIAA1623
- KNG
- KNG1
- KTN1
- KUZ
- LAMB1
- LAMB2
- LAMC1
- LAMS
- LGALS1
- LPLUNC2
- LTBP1
- MAC25
- MADM
- MAP97
- MATN3
- MBTPS1
- MELTF
- MEN1
- MEPE
- MFGE8
- MFI2
- MGAT4A
- MIA3
- MPF
- MSLN
- MXRA8
- NARC1
- NCAD
- NOTUM
- NRLN1
- NUC
- NUCB1
- OCI5
- OPN
- P4HB
- P5
- P58IPK
- PCSK9
- PDI
- PDIA1
- PDIA6
- PENK
- PI
- PNPLA2
- PO4DB
- PRKCSH
- PRKRI
- PROC
- PRSS23
- PSF
- QSCN6
- QSOX1
- RAP3
- RCN
- RCN1
- S1P
- SCG1
- SCG2
- SCG3
- SCOTIN
- SDC2
- SERPINA1
- SERPINA10
- SERPINC1
- SERPIND1
- SHISA5
- SKI1
- SPARCL1
- SPP1
- SPP2
- SPP24
- STC2
- TANGO
- TF
- TGN46
- TGN51
- TGOLN2
- TIMP
- TIMP1
- TMEM132A
- TMEM166
- TMEM16H
- TNC
- TRA1
- TXNDC7
- VCAN
- VGF
- VWA1
- WFS1
- ZPI
- ZSIG13
|
|
cell division
|
|
|
- KIF20A
- KIF23
- KNSL5
- MKLP1
- MKLP2
- PLK
- PLK1
- RAB6KIFL
|
|
Spry regulation of FGF signaling
|
|
|
- BRAF
- BRAF1
- CBL
- CBL2
- ERK1
- ERK2
- MAPK1
- MAPK3
- MKNK1
- MNK1
- PPP2CA
- PPP2CB
- PPP2R1A
- PRKM1
- PRKM2
- PRKM3
- PTP2C
- PTPN11
- RAFB1
- RNF55
- RPS27A
- SHPTP2
- SPRY2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
|
|
mRNA decay by 3' to 5' exoribonuclease
|
|
|
- CML28
- CSL4
- DCPS
- DCS1
- DDX13
- DIS3
- EXOSC1
- EXOSC2
- EXOSC3
- EXOSC4
- EXOSC5
- EXOSC6
- EXOSC7
- EXOSC8
- EXOSC9
- HBS1
- HBS1L
- HINT5
- KIAA0116
- KIAA0372
- KIAA1008
- KIAA1038
- MTR3
- NT5C3B
- NT5C3L
- OIP2
- PMSCL1
- RRP4
- RRP40
- RRP41
- RRP42
- RRP43
- RRP44
- RRP46
- SKI2W
- SKI6
- SKIC2
- SKIC3
- SKIC8
- SKIV2
- SKIV2L
- TTC37
- W
- WDR61
|
|
Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F)
|
|
|
|
|
Inositol transporters
|
|
|
- KST1
- SLC2A13
- SLC5A11
- SLC5A3
- SLGTX
- SMIT2
|
|
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
|
|
|
- CILP
- IBP1
- IGF1
- IGF1R
- IGF2
|
|
GRB2:SOS provides linkage to MAPK signaling for Integrins
|
|
|
- APBB1IP
- F8VWF
- FAK
- FAK1
- FGA
- FGB
- FGG
- FN
- FN1
- GP2B
- GP3A
- ITGA2B
- ITGAB
- ITGB3
- KIAA1027
- KREV1
- PREL1
- PTK2
- RAP1A
- RAP1B
- RARP1
- RIAM
- SOS1
- SRC
- SRC1
- TLN
- TLN1
- VWF
|
|
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
|
|
|
- DDX2A
- DDX2B
- EIF4A
- EIF4A1
- EIF4A2
- EIF4B
- EIF4E
- EIF4EBP1
- EIF4EL1
- EIF4F
- EIF4G
- EIF4G1
- EIF4GI
- EIF4H
- KIAA0038
- WBSCR1
- WSCR1
|
|
ABC transporters in lipid homeostasis
|
|
|
- ABC12
- ABC2
- ABC3
- ABC8
- ABCA10
- ABCA12
- ABCA2
- ABCA3
- ABCA5
- ABCA6
- ABCA7
- ABCA9
- ABCD1
- ABCD2
- ABCD3
- ABCG1
- ABCG4
- ABCG5
- ABCG8
- ALD
- ALD1
- ALDL1
- ALDR
- ALDRP
- APOA1
- HK33
- KIAA1062
- KIAA1888
- PEX19
- PEX3
- PMP70
- PXF
- PXMP1
- WHITE2
- WHT1
|
|
Adherens junctions interactions
|
|
|
- ANG
- CADM1
- CADM2
- CADM3
- CDH1
- CDH10
- CDH11
- CDH11L
- CDH12
- CDH13
- CDH14
- CDH15
- CDH17
- CDH18
- CDH2
- CDH24
- CDH3
- CDH4
- CDH5
- CDH6
- CDH7
- CDH7L1
- CDH8
- CDH9
- CDHE
- CDHH
- CDHN
- CDHP
- CTNNA1
- CTNNB
- CTNNB1
- CTNND1
- CTNNG
- DP3
- HVEB
- HVEC
- IGSF4
- IGSF4A
- IGSF4B
- IGSF4D
- JUP
- KIAA0384
- LNIR
- NCAD
- NECL1
- NECL2
- NECL3
- NECTIN1
- NECTIN2
- NECTIN3
- NECTIN4
- PRR1
- PRR2
- PRR3
- PRR4
- PVRL1
- PVRL2
- PVRL3
- PVRL4
- RNASE5
- SYNCAM
- SYNCAM3
- TSLC1
- TSLL1
- UVO
|
|
Glucagon-type ligand receptors
|
|
|
- ADCYAP1
- ADCYAP1R1
- GCG
- GCGR
- GHRF
- GHRH
- GHRHR
- GIP
- GIPR
- GLP1R
- GLP2R
- GNAS
- GNAS1
- GNB1
- GNB2
- GNB3
- GNB4
- GNB5
- GNG10
- GNG11
- GNG12
- GNG13
- GNG2
- GNG3
- GNG4
- GNG5
- GNG7
- GNG8
- GNG9
- GNGT1
- GNGT10
- GNGT11
- GNGT2
- GNGT3
- GNGT4
- GNGT5
- GNGT7
- GNGT8
- GNGT9
- GSP
- SCT
- SCTR
- VIP
- VIP2R
- VIPR1
- VIPR2
|
|
ARL13B-mediated ciliary trafficking of INPP5E
|
|
|
- ARL13B
- ARL2L1
- INPP5E
- PDE6D
- PDED
|
|
NEIL3-mediated resolution of ICLs
|
|
|
|
|
Biosynthesis of aspirin-triggered D-series resolvins
|
|
|
|
|
Cleavage of the damaged pyrimidine
|
|
|
- ACD
- DRIP5
- H2AB1
- H2AC14
- H2AC18
- H2AC19
- H2AC20
- H2AC4
- H2AC6
- H2AC7
- H2AC8
- H2AFA
- H2AFB1
- H2AFE
- H2AFG
- H2AFJ
- H2AFL
- H2AFM
- H2AFO
- H2AFQ
- H2AFV
- H2AFX
- H2AJ
- H2AV
- H2AX
- H2AZ2
- H2BC1
- H2BC10
- H2BC11
- H2BC12
- H2BC12L
- H2BC13
- H2BC14
- H2BC15
- H2BC17
- H2BC21
- H2BC26
- H2BC3
- H2BC4
- H2BC5
- H2BC6
- H2BC7
- H2BC8
- H2BC9
- H2BFA
- H2BFB
- H2BFC
- H2BFD
- H2BFE
- H2BFF
- H2BFG
- H2BFH
- H2BFJ
- H2BFK
- H2BFL
- H2BFN
- H2BFQ
- H2BFR
- H2BFS
- H2BFT
- H2BS1
- H2BU1
- H3-4
- H3FT
- H4-16
- H4/A
- H4/B
- H4/C
- H4/D
- H4/E
- H4/G
- H4/H
- H4/I
- H4/J
- H4/K
- H4/M
- H4/N
- H4/O
- H4C1
- H4C11
- H4C12
- H4C13
- H4C14
- H4C15
- H4C16
- H4C2
- H4C3
- H4C4
- H4C5
- H4C6
- H4C8
- H4C9
- H4F2
- H4FA
- H4FB
- H4FC
- H4FD
- H4FE
- H4FG
- H4FH
- H4FI
- H4FJ
- H4FK
- H4FM
- H4FN
- H4FO
- HIRIP1
- HIRIP2
- HIST1H2AB
- HIST1H2AC
- HIST1H2AD
- HIST1H2AE
- HIST1H2AJ
- HIST1H2BA
- HIST1H2BB
- HIST1H2BC
- HIST1H2BD
- HIST1H2BE
- HIST1H2BF
- HIST1H2BG
- HIST1H2BH
- HIST1H2BI
- HIST1H2BJ
- HIST1H2BK
- HIST1H2BL
- HIST1H2BM
- HIST1H2BN
- HIST1H2BO
- HIST1H4A
- HIST1H4B
- HIST1H4C
- HIST1H4D
- HIST1H4E
- HIST1H4F
- HIST1H4H
- HIST1H4I
- HIST1H4J
- HIST1H4K
- HIST1H4L
- HIST2H2AA
- HIST2H2AA3
- HIST2H2AA4
- HIST2H2AC
- HIST2H2BE
- HIST2H4
- HIST2H4A
- HIST2H4B
- HIST3H2BB
- HIST3H3
- HIST4H4
- MBD4
- MED1
- MMH
- MUTM
- NEIL1
- NEIL2
- NEIL3
- NTH1
- NTHL1
- OCTS3
- OGG1
- OGH1
- PIN2
- PIP1
- POT1
- PTOP
- RAP1
- SMUG1
- TDG
- TERF1
- TERF2
- TERF2IP
- TIN2
- TINF2
- TINT1
- TPP1
- TRBF1
- TRBF2
- TRF
- TRF1
- TRF2
- TSH2B
|
|
Glutamate Neurotransmitter Release Cycle
|
|
|
- ARL6IP5
- ATA2
- BNPI
- BZRAP1
- CPLX1
- DERP11
- EAAC1
- EAAT1
- EAAT2
- EAAT3
- EAAT4
- EAAT5
- GA
- GLAST
- GLAST1
- GLS
- GLS1
- GLS2
- GLT1
- HEAAC1
- JWA
- KIAA0340
- KIAA0612
- KIAA0654
- KIAA0838
- KIAA0897
- KIAA1382
- LIP1
- PPFIA1
- PPFIA2
- PPFIA3
- PPFIA4
- PRA2
- PRAF3
- RAB3A
- RAB3IP2
- RBP1
- RIM1
- RIMBP1
- RIMS1
- SAT2
- SLC17A7
- SLC1A1
- SLC1A2
- SLC1A3
- SLC1A6
- SLC1A7
- SLC38A2
- SNAP
- SNAP25
- SNAT2
- STX1
- STX1A
- SVP65
- SYB2
- SYT
- SYT1
- TSPOAP1
- UNC13
- UNC13B
- VAMP2
- VGLUT1
|
|
Platelet degranulation
|
|
|
- A1BG
- A2M
- A4
- AACT
- AAP
- AAT
- ABCC4
- ACTBL3
- ACTN1
- ACTN2
- ACTN4
- AD1
- AGP1
- AGP2
- AHSG
- ALB
- ALDA
- ALDOA
- ANX5
- ANXA5
- APLP2
- APOA1
- APOH
- APOJ
- APOOL
- APP
- APPL2
- ARMET
- ARP
- AXLLG
- B2G1
- BCG1
- BDK
- BHPCDH
- BRPF3
- C1IN
- C1NH
- C6orf21
- C6orf56
- C9orf167
- CALM
- CALM1
- CALU
- CAM
- CAM1
- CAP
- CAP1
- CD109
- CD36
- CD63
- CD9
- CDC37B
- CDC37L1
- CFD
- CFL
- CFL1
- CHID1
- CLEC3B
- CLGI
- CLI
- CLU
- CPAMD5
- CPAMD7
- CTAP3
- CTSW
- CXCL4
- CXCL7
- CXorf33
- CYB5R1
- CYPA
- CYRI
- CYRIB
- DF
- EBAF
- ECM
- ECM1
- EGF
- EMILIN4
- ENDOD1
- ENX2
- F13A
- F13A1
- F5
- F8
- F8C
- F8VWF
- FAM121A
- FAM3C
- FAM49B
- FERMT3
- FETUA
- FGA
- FGB
- FGG
- FIGF
- FLN
- FLN1
- FLNA
- FN
- FN1
- G6F
- GAS6
- GLBA
- GMRP
- GP2B
- GP3A
- GP3B
- GP4
- GPIA*
- GRMP
- GRP78
- GTPBP2
- GTPBP9
- HABP4
- HARC
- HGF
- HPTA
- HRG
- HSPA5
- IBP1
- IGF1
- IGF2
- IHRP
- ILEI
- ISLR
- ITGA2B
- ITGAB
- ITGB3
- ITIH3
- ITIH4
- ITIHL1
- KIAA0120
- KIAA0206
- KIAA0680
- KIAA0830
- KIAA1027
- KIAA1286
- KIAA1830
- KIND3
- KNG
- KNG1
- KST
- KUB1
- LAMP2
- LEFTA
- LEFTY2
- LEFTYA
- LGALS3BP
- LHFPL2
- LY6G6D
- LY6G6F
- M2BP
- MAGED2
- MANF
- MIC27
- MIC3
- MIG2B
- MLA1
- MMRN
- MMRN1
- MOATB
- MRP4
- NG32
- NHLRC2
- NQO3A2
- OLA1
- ON
- ORM1
- ORM2
- P47
- PAI1
- PCDH7
- PCYOX1L
- PDGF2
- PDGFB
- PECAM1
- PF4
- PFD
- PFN1
- PHACTR2
- PI
- PI4
- PK120
- PLANH1
- PLEK
- PLG
- PLI
- POTEKP
- PP4
- PPBP
- PPIA
- PRG
- PRG1
- PROS
- PROS1
- PSAP
- QSCN6
- QSOX1
- RAB27B
- RARRES2
- SAP1
- SCCPDH
- SCG3
- SCYB4
- SCYB7
- SELENOP
- SELP
- SEPP1
- SERPINA1
- SERPINA3
- SERPINA4
- SERPINE1
- SERPINF2
- SERPING1
- SIS
- SOD1
- SPARC
- SPP2
- SPP24
- SRGN
- STXBP2
- SYTL4
- TAGLN2
- TB4X
- TEX264
- TF
- TGB1
- TGFB
- TGFB1
- TGFB2
- TGFB3
- TGFB4
- THBGB1
- THBS1
- THYB4
- TIG2
- TIMP
- TIMP1
- TIMP3
- TLN
- TLN1
- TMSB4
- TMSB4X
- TMX3
- TNA
- TOR4A
- TSP
- TSP1
- TSPAN29
- TSPAN30
- TTN
- TUBA1
- TUBA4A
- TXNDC10
- UNC18B
- URP2
- VCL
- VEGF
- VEGFA
- VEGFB
- VEGFC
- VEGFD
- VRF
- VTI1
- VTI1B
- VTI1L
- VTI1L1
- VTI2
- VWF
- WDR1
- ZSIG11
|
|
Defective CBLIF causes IFD
|
|
|
|
|
Interleukin-1 signaling
|
|
|
- BLU
- BTRC
- BTRCP
- C7orf76
- CARD15
- CARD4
- CARDIAK
- CHUK
- CROC1
- CUL1
- DSS1
- EMC19
- FBW1A
- FBXW1A
- FIP3
- HC2
- HC3
- HC8
- HC9
- HSPC
- IFI5111
- IKBA
- IKBKB
- IKBKG
- IKKA
- IKKB
- IL1A
- IL1B
- IL1F1
- IL1F2
- IL1F3
- IL1R
- IL1R1
- IL1R2
- IL1RA
- IL1RB
- IL1RN
- IL1RT1
- IRAK
- IRAK1
- IRAK2
- IRAK3
- IRAK4
- KIAA0072
- KIAA0077
- KIAA0107
- KIAA0733
- LMP10
- LMP2
- LMP7
- LMPX
- LMPY
- MAD3
- MAP2K6
- MAP3K3
- MAP3K7
- MAP3K7IP1
- MAP3K7IP2
- MAP3K7IP3
- MAPKKK3
- MB1
- MCB1
- MECL1
- MEK6
- MEKK3
- MIP224
- MKK6
- MOV34L
- MSS1
- MYD88
- N
- NEMO
- NFKB1
- NFKB3
- NFKBI
- NFKBIA
- NOD1
- NOD2
- NU
- OCP2
- ORCA
- OSIL
- PELI1
- PELI2
- PELI3
- PFAAP4
- POH1
- PRISM
- PRKMK6
- PROS26
- PROS27
- PROS30
- PSC2
- PSC3
- PSC5
- PSC8
- PSC9
- PSMA1
- PSMA2
- PSMA3
- PSMA4
- PSMA5
- PSMA6
- PSMA7
- PSMA7L
- PSMA8
- PSMB1
- PSMB10
- PSMB11
- PSMB2
- PSMB3
- PSMB4
- PSMB5
- PSMB5i
- PSMB6
- PSMB6i
- PSMB7
- PSMB8
- PSMB9
- PSMC1
- PSMC2
- PSMC3
- PSMC4
- PSMC5
- PSMC6
- PSMD1
- PSMD10
- PSMD11
- PSMD12
- PSMD13
- PSMD14
- PSMD2
- PSMD3
- PSMD4
- PSMD5
- PSMD6
- PSMD7
- PSMD8
- PSMD9
- PSME1
- PSME2
- PSME3
- PSME4
- PSMF1
- RBX1
- RELA
- RICK
- RING10
- RING12
- RIP2
- RIPK2
- RNF75
- RNF85
- ROC1
- RPS27A
- SEM1
- SHFDG1
- SHFM1
- SKK3
- SKP1
- SKP1A
- SQSTM1
- SUG1
- SUG2
- TAB1
- TAB2
- TAB3
- TAK1
- TBP1
- TBP7
- TCEB1L
- TCF16
- TOLLIP
- TRAF6
- TRAP2
- UBA52
- UBA80
- UBB
- UBC
- UBCEP1
- UBCEP2
- UBE2N
- UBE2V
- UBE2V1
- UEV1
- X
- Y
- Y2
- Z
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Molecules associated with elastic fibres
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- BMP10
- BMP14
- BMP2
- BMP2A
- BMP2B
- BMP4
- BMP7
- C14orf141
- CDMP1
- DANCE
- DVR4
- EFEMP1
- EFEMP2
- FBLN1
- FBLN2
- FBLN3
- FBLN4
- FBLN5
- FBNL
- FNRB
- GDF5
- GP3A
- ITGA8
- ITGAV
- ITGB1
- ITGB3
- ITGB5
- ITGB6
- ITGB8
- LTBP1
- LTBP2
- LTBP3
- LTBP4
- MAGP1
- MAGP2
- MDF2
- MFAP2
- MFAP3
- MFAP4
- MFAP5
- MSK12
- MSK8
- OP1
- TGFB
- TGFB1
- TGFB2
- TGFB3
- VNRA
- VTN
- VTNR
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Beta defensins
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- BD1
- BD3
- BD5
- BD6
- C20orf63
- C20orf73
- C20orf8
- C20orf87
- CCR2
- CCR6
- CKRL3
- CMKBR2
- CMKBR6
- DEFB1
- DEFB10
- DEFB102
- DEFB103
- DEFB103A
- DEFB103B
- DEFB104
- DEFB104A
- DEFB104B
- DEFB105
- DEFB105A
- DEFB105B
- DEFB106
- DEFB106A
- DEFB106B
- DEFB107
- DEFB107A
- DEFB107B
- DEFB108
- DEFB108A
- DEFB108B
- DEFB108C
- DEFB108P1
- DEFB108P2
- DEFB109B
- DEFB109P1B
- DEFB11
- DEFB110
- DEFB111
- DEFB112
- DEFB113
- DEFB114
- DEFB115
- DEFB116
- DEFB117
- DEFB118
- DEFB119
- DEFB12
- DEFB120
- DEFB121
- DEFB123
- DEFB124
- DEFB125
- DEFB126
- DEFB127
- DEFB128
- DEFB129
- DEFB13
- DEFB130
- DEFB130A
- DEFB130B
- DEFB131
- DEFB131A
- DEFB132
- DEFB133
- DEFB134
- DEFB135
- DEFB136
- DEFB14
- DEFB15
- DEFB16
- DEFB18
- DEFB19
- DEFB2
- DEFB20
- DEFB21
- DEFB23
- DEFB24
- DEFB25
- DEFB26
- DEFB27
- DEFB28
- DEFB29
- DEFB3
- DEFB30
- DEFB31
- DEFB32
- DEFB4
- DEFB4A
- DEFB4B
- DEFB5
- DEFB6
- DEFB7
- DEFB8
- ESC42
- GPR29
- HBD1
- KIAA0012
- STRL22
- TIL4
- TLR1
- TLR2
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Phase I - Functionalization of compounds
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- AADAC
- ABP
- ABP1
- AHR
- AHRR
- ALDH3
- ALDH3A1
- AOC1
- AOC2
- AOC3
- ARNT
- ARNT2
- BHLHE1
- BHLHE2
- BHLHE76
- BHLHE77
- BPHL
- CBR3
- CES1
- CES2
- CES3
- CMBL
- CYB5B
- CYB5M
- CYB5R3
- CYP2B6
- CYP3A3
- CYP3A4
- DAC
- DAO
- DIA1
- EPHX
- EPHX1
- EPOX
- ICE
- KIAA0307
- KIAA1234
- MARC1
- MARC2
- MCNAA
- MOSC1
- MOSC2
- MTARC1
- MTARC2
- NMOR2
- NQO2
- OMB5
- SDR21C2
- SES1
- VAP1
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