Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Database | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▲ | PubMed ID |
|---|---|---|---|---|---|---|---|
|
Fibrillar hemmagglutinin
|
N-acetylneuraminyl-a(2-3)-galactopyranosyl sequence
|
Glycoproteins
|
Gastric epithelium, Mucus layer of the stomach
|
NeuAc(a2-3)Gal
|
Binding
|
||
|
SV40
|
GM1
|
Monosialoglycosphingolipids
|
(broad range)
|
Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Adhesins
|
Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside)
|
Monosialoglycosphingolipids
|
Human leukocytes, Human neutrophils
|
NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
K99
|
GM3(NeuGc)
|
Monosialoglycosphingolipids
|
Pig small intestine
|
NeuGc(a2-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
CS3 (coli surface 3)-fimbriae
|
GM1
|
Monosialoglycosphingolipids
|
Intestinal epithelium, Rabbit intestine
|
Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
CS3 (coli surface 3)-fimbriae
|
GM2(NeuAc)
|
Monosialoglycosphingolipids
|
Intestinal epithelium, Rabbit intestine
|
GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Fimbriae
|
GM2(NeuAc)
|
Monosialoglycosphingolipids
|
Human pharyngeal epithelial cells
|
GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Unknown
|
GM3(NeuAc)
|
Monosialoglycosphingolipids
|
Granulocytes
|
NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Unknown
|
Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside)
|
Monosialoglycosphingolipids
|
Granulocytes
|
NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
|
Adhesins
|
GM3(NeuAc)
|
Monosialoglycosphingolipids
|
Human gastric mucosa
|
NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
Displaying entries 11 - 20 of 1840 in total
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International Collaboration
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Acknowledgements
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
