Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Species Pathogen Adherence Molecule Ligand Name Ligand Feature Target Source Glycan Sequence Binding PubMed ID ▲
PT (subunit S3 of B oligomer)
Gangliosides
Sialoglycosphingolipids
Human alveolar macrophages
Binding
Pertussis toxin
Gangliosides
Sialoglycosphingolipids
Human alveolar macrophages
Binding
PT (subunits S2/S3 of B oligomer)
Glucosylceramide
Monoglycosylceramides
Human cilia of the respiratory epithelium
Glc(b1-1)Cer
Binding
Pertussis toxin
Glucosylceramide
Monoglycosylceramides
Human cilia of the respiratory epithelium
Glc(b1-1)Cer
Binding
Pertussis toxin
Lactosylceramide (Lactocerebroside)
Diosylceramides
Human cilia of the respiratory epithelium
Gal(b1-4)Glc(b1-1)Cer
Binding
PT (subunit S2 of B oligomer)
Lactosylceramide (Lactocerebroside)
Diosylceramides
Human cilia of the respiratory epithelium
Gal(b1-4)Glc(b1-1)Cer
Binding
Pertussis toxin
Haptoglobin
Glycoproteins
Binding
PT (subunit S2 of B oligomer)
Haptoglobin
Glycoproteins
Binding
Unknown
Salivary glycoprotein
Glycoproteins
Human saliva
Binding
Unknown
GD1a
Disialoglycosphingolipids
NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer
Binding
Displaying entries 11 - 20 of 1840 in total

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01