GlyCosmos Portal

Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Database	Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB)	June 1, 2016

Species	Pathogen Adherence Molecule	Ligand Name	Ligand Feature	Target Source	Glycan Sequence	Binding	PubMed ID ▲
Human immunodeficiency virus	Envelope glycoprotein gp120	Galactosylceramide (Galactocerebroside)	Monoglycosylceramides	Neural receptor	Gal(b1-1)Cer	Binding	1871126
Fusobacterium nucleatum	Lectin-like proteins (adhesin)	unnamed ligand	Oligosaccharides		Gal(b1-4)GlcNAc	Binding	1894623
Fusobacterium nucleatum	Lectin-like proteins (adhesin)	unnamed ligand	Oligosaccharides		Gal(b1-3)GalNAc	Binding	1894623
Fusobacterium nucleatum	Lectin-like proteins (adhesin)	Mr 36,900 PRG (Proline-Rich Glycoprotein)	Glycoproteins			Binding	1894623
Fusobacterium nucleatum	Lectin-like proteins (adhesin)	Mr 89,000 PRG (Proline-Rich Glycoprotein)	Glycoproteins			Binding	1894623
Bordetella pertussis	Adhesins	terminal Gal(3SO4) β1- residues	Sulfoglycosphingolipids	Human lung, Human trachea	Gal(3SO4)(b	Binding	1918002
Bordetella parapertussis	Adhesins	terminal Gal(3SO4) β1- residues	Sulfoglycosphingolipids		Gal(3SO4)(b	Binding	1918002
Bordetella pertussis	Adhesins	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides	Human lung, Human trachea	Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	1918002
Bordetella parapertussis	Adhesins	Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1)	Oligoglycosylceramides		Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer	Binding	1918002
Helicobacter pylori	Adhesins	GM3(NeuAc)	Monosialoglycosphingolipids	Human gastric mucosa	NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer	Binding	2037054