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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature ▼ | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Yersinia pestis | PsaA/B (pH-6 antigen) | GQ1b | Tetrasialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9712817 | |
| Escherichia coli | Unknown | GQ1b | Tetrasialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Bordetella pertussis | Adhesins | terminal Gal(3SO4) β1- residues | Sulfoglycosphingolipids | Human lung, Human trachea | Gal(3SO4)(b | Binding | 1918002 |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Sulfatide (CSE) | Sulfoglycosphingolipids | Cell surface | HSO3(-3)Gal(b1-1)Cer | Binding | 10341176 |
| Mycoplasma pneumoniae | Adhesins | Sulfatide (CSE) | Sulfoglycosphingolipids | Erythrocytes | HSO3(-3)Gal(b1-1)Cer | Binding | 2470754 |
| Helicobacter pylori | Adhesins | Sulfatide (CSE) | Sulfoglycosphingolipids | Human gastric mucosa | HSO3(-3)Gal(b1-1)Cer | Binding | 2037054 |
| Mycoplasma pneumoniae | Unknown | Sulfo-lactosylceramide (SM3) | Sulfoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | HSO3(-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Human immunodeficiency virus | gp120 | Sulfatide (CSE) | Sulfoglycosphingolipids | Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Sulfatide (CSE) | Sulfoglycosphingolipids | Human meconium | HSO3(-3)Gal(b1-1)Cer | Binding | 9228091 |
| Human immunodeficiency virus | Envelope glycoprotein gp120 | Galactosyl sulfatide | Sulfoglycosphingolipids | Neural receptor | HSO3(-3)Gal(b1-1)Cer | Binding | 1871126 |
| Lactobacillus casei | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | Intestinal tract | HSO3(-3)Gal(b1-1)Cer | Binding | 8912650 |
| Escherichia coli | SfaA | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 | |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 8574698 | |
| Escherichia coli | S-fimbriae | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 | |
| Helicobacter pylori | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 16088272 | |
| Bordetella parapertussis | Adhesins | terminal Gal(3SO4) β1- residues | Sulfoglycosphingolipids | Gal(3SO4)(b | Binding | 1918002 | |
| Cytomegalovirus | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 9780061 | |
| Cytomegalovirus | Unknown | Sulfo-lactosylceramide (SM3) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9780061 | |
| Bordetella pertussis | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 15973004 | |
| Plasmodium falciparum | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 8574698 | |
| Actinobacillus pleuropneumoniae | LPS | Sulfatide (CSE) | Sulfoglycosphingolipids | HSO3(-3)Gal(b1-1)Cer | Binding | 10496867 | |
| Escherichia coli | S-fimbriae (SfaA) | Galactosyl sulfatide | Sulfoglycosphingolipids | Brain endothelial cells | Gal(3SO4)(b1-1)Cer | Binding | 8098039 |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | Sulfatide (CSE) | Sulfoglycosphingolipids | Piglet intestine | HSO3(-3)Gal(b1-1)Cer | Not Binding | 9499377 |
| Escherichia coli | F1C | Sulfatide (CSE) | Sulfoglycosphingolipids | Porcine intestine | HSO3(-3)Gal(b1-1)Cer | Not Binding | 11877427 |
| Mycoplasma pneumoniae | Unknown | Galactosylceramide 6-sulfate | Sulfoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | Gal(6SO4)(b1-1)Cer | Binding | 2470753 |
