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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding ▲ | PubMed ID |
|---|---|---|---|---|---|---|---|
| Rotavirus | Unknown | Sialyl Lewis a (SLea) (GSL) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Escherichia coli | Unknown | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Parvovirus | Unknown | SSEA-4 (GSL) (Sialosyl galactosyl globoside; SGG; sialyl Gb5) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Influenza virus | Hemagglutinin (HA) | Sialyl-6-Paragloboside (S-6-PG; α2,6-sialylparagloboside) | Monosialoglycosphingolipids | NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Adeno-associated virus | Unknown | NeuAcα2-3GalNAcβ1-4GlcNAc | Oligosaccharides | NeuAc(a2-3)GalNAc(b1-4)GlcNAc | Binding | 16940521 | |
| Mumps virus | MuV-HN | Glycans containing α2,3-linked sialic acid | Oligosaccharides | NeuAc(a2-3)Gal(b1-4)GlcNAc | Binding | 27671656 | |
| Mumps virus | MuV-HN | Glycans containing α2,3-linked sialic acid | Oligosaccharides | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-4]Man(a1-3)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc | Binding | 27671656 | |
| Influenza virus | Unknown | I-active ganglioside | Sialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Influenza virus | Unknown | NeuAc6-Lc4Cer (Sialyl lactotetraosylceramide) | Sialoglycosphingolipids | NeuAc(a2-6)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Influenza virus | Unknown | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Rotavirus | Unknown | I-active Sialyl lactoisooctaosylceramide | Sialoglycosphingolipids | Gal(a1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Rotavirus | Unknown | NeuGc3-nLc6Cer | Sialoglycosphingolipids | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Escherichia coli | Unknown | unnamed ligand | Sialoglycosphingolipids | NeuAc(a2-6)[NeuAc(a2-3)]Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2435422 | |
| Influenza virus | Hemagglutinin (HA) | I-active ganglioside | Sialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Influenza virus | Hemagglutinin (HA) | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12628483 | |
| Helicobacter pylori | Unknown | NeuAc3-nLc6Cer (Sialyl neolactohexaosylceramide) | Sialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9169796 | |
| Cytomegalovirus | Unknown | SGPG (Sulfated glucuronyl paragloboside) | Sulfoglycosphingolipids | HSO3(-3)GlcA(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9780061 | |
| Cytomegalovirus | Unknown | Bis-sulfogangliotriaosylceramide (SB2) | Sulfoglycosphingolipids | HSO3(-3)GalNAc(b1-4)[HSO3(-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 9780061 | |
| Cytomegalovirus | Unknown | SGLPG (Sulfated glucuronyl lactosaminyl paragloboside) | Sulfoglycosphingolipids | HSO3(-3)GlcA(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 9780061 | |
| Mycoplasma pneumoniae | Unknown | Galactosyl sulfatide | Sulfoglycosphingolipids | Gal(3SO4)(b1-1)Cer | Binding | 12628483 | |
| Escherichia coli | Heat-labile enterotoxin (type II(LT-Iia)) | GQ1b | Tetrasialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Clostridium tetani | Tetanus toxin | GQ1b | Tetrasialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Escherichia coli | A and B polypeptide subunits | GQ1b | Tetrasialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3290106 | |
| Clostridium tetani | Unknown | GQ1b | Tetrasialoglycosphingolipids | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 |
