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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name ▼ | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Bordetella pertussis | Pertussis toxin | Gangliosides | Sialoglycosphingolipids | Human alveolar macrophages | Binding | 1729677 | |
| Influenza virus | Unknown | Gangliosides | Sialoglycosphingolipids | Bovine brain | Binding | 1740131 | |
| Rotavirus | TLP (Triple-layered virus particles) | Gangliosides | Sialoglycosphingolipids | Binding | 10659372 | ||
| Borrelia burgdorferi | "OspA, OspB, OspC" | Gangliosides | Sialoglycosphingolipids | Binding | 16299269 | ||
| Influenza virus | Hemagglutinin (HA) | Gangliosides | Glycosphingolipids | Human leukocytes | Binding | 11030743 | |
| Helicobacter pylori | Unknown | Ganglio glycolipids | Glycosphingolipids | Binding | 16088272 | ||
| Mycoplasma pneumoniae | Unknown | Galactosylceramide 6-sulfate | Sulfoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | Gal(6SO4)(b1-1)Cer | Binding | 2470753 |
| Escherichia coli | F1C | Galactosylceramide (t18:0-h22:0-h24:0) | Monoglycosylceramides | Human kidney | Gal(b1-1)Cer | Binding | 11877427 |
| Human immunodeficiency virus | Unknown | Galactosylceramide (or derivative) | Monoglycosylceramides | Human colon epithelial HT29 cells | Gal(b1-1)Cer | Binding | 1378511 |
| Escherichia coli | PsaA/B (pH-6 antigen) | Galactosylceramide (nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 9712817 | |
| Escherichia coli | F1C | Galactosylceramide (nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 10816509 | |
| Yersinia pestis | PsaA/B (pH-6 antigen) | Galactosylceramide (nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Not Binding | 9712817 | |
| Escherichia coli | PsaA/B (pH-6 antigen) | Galactosylceramide (hydroxylated/nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 9712817 | |
| Actinobacillus pleuropneumoniae | LPS | Galactosylceramide (hydroxylated/nonhydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 10496867 | |
| Yersinia pestis | PsaA/B (pH-6 antigen) | Galactosylceramide (hydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 9712817 | |
| Escherichia coli | F1C | Galactosylceramide (hydroxylated fatty acids) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 10816509 | |
| Escherichia coli | F1C | Galactosylceramide (d18:1-h18:0-h24:0) | Monoglycosylceramides | Sigma | Gal(b1-1)Cer | Not Binding | 11877427 |
| Human immunodeficiency virus | gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human colonic epithelial cell lines (HT-29/HT-29-A7/HT-29-D4) | Gal(b1-1)Cer | Binding | 8464878 |
| Burkholderia cepacia | Lectin-like proteins (adhesin) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Sputa of cystic fibrosis patients | Gal(b1-1)Cer | Binding | 8606110 |
| Escherichia coli | S-fimbriae (SfaA) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Brain endothelial cells | Gal(b1-1)Cer | Binding | 8098039 |
| Human immunodeficiency virus | HIV surface glycoprotein gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Neural cell lines | Gal(b1-1)Cer | Binding | 1857969 |
| Human immunodeficiency virus | gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells | Gal(b1-1)Cer | Binding | 15973004 |
| Human immunodeficiency virus | Envelope glycoprotein gp120 | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Neural receptor | Gal(b1-1)Cer | Binding | 1871126 |
| Escherichia coli | SfaA | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 15973004 | |
| Escherichia coli | S-fimbriae | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Gal(b1-1)Cer | Binding | 15973004 |
