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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▲ |
|---|---|---|---|---|---|---|---|
| Borrelia burgdorferi | Unknown | Dermatan sulfate | Glycosaminoglycans | Glial cells | Binding | 10085013 | |
| Streptococcus pneumoniae | Unknown | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Chinchilla tracheal epithelium | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 10090858 |
| Streptococcus pneumoniae | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Chinchilla tracheal epithelium | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 10090858 |
| Vibrio cholerae | MSHA (mannose/glucose-specific hemagglutinin) | Mannose | Monosaccharides | Patient with acute watery diarrhea | Man | Binding | 10219594 |
| Vibrio cholerae | MSHA (mannose/glucose-specific hemagglutinin) | Glucose | Monosaccharides | Patient with acute watery diarrhea | Glc | Binding | 10219594 |
| Entamoeba histolytica | Membrane-associated lectins (heavy(170-kDa)/light(35-or31-kDa) subunits) | N-Acetylgalactosamine | Monosaccharides | GalNAc | Binding | 10225860 | |
| Entamoeba histolytica | Membrane-associated lectins (heavy(170-kDa)/light(35-or31-kDa) subunits) | Galactose | Monosaccharides | Gal | Binding | 10225860 | |
| Bordetella pertussis | FHA (filamentous hemagglutinin) | Sulfatide (CSE) | Sulfoglycosphingolipids | Cell surface | HSO3(-3)Gal(b1-1)Cer | Binding | 10341176 |
| Escherichia coli | SfaS | unnamed ligand | Glycoconjugates | NeuAc(a2-3)Gal(b | Binding | 10341176 | |
| Haemophilus influenzae | HifE (Pili family) | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 10341176 | |
| Streptococcus pneumoniae | CbpA; SpsA; PbcA; PspC (CBPs) | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Cytokine activated epithelial and endothelial cells | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 10341176 |
| Escherichia coli | PapG | Gal(a1-4)Gal in globo-series of glycolipids | Glycosphingolipids | Gal(a1-4)Gal | Binding | 10341176 | |
| Escherichia coli | PrsG | Gal(a1-4)Gal in globo-series of glycolipids | Glycosphingolipids | Gal(a1-4)Gal | Binding | 10341176 | |
| Escherichia coli | FimH | Mannose oligosaccharides | Oligosaccharides | Man | Binding | 10341176 | |
| Escherichia coli | Pertactin | Mannose oligosaccharides | Oligosaccharides | Man | Binding | 10341176 | |
| Streptococcus sobrinus | SpaA (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | P1 (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus sanguis | SsaB (Lral family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus gordonii | SspA (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | SpaP (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | Pac (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus sobrinus | Pag (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus mutans | Ag I/II (Antigen I/II Family) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus gordonii | SspB (Antigen I/II) | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 | |
| Streptococcus parasanguinis | FimA (Lral family); localized to the tip of peritrichous surface fimbria | Salivary glycoprotein | Glycoproteins | Tooth surface | Binding | 10341176 |
