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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID ▼ |
|---|---|---|---|---|---|---|---|
| Candida albicans | "Extracellular polymeric material, acid proteinase, chitin" | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human buccal epihelial cells (BECs) | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8005674 |
| Candida albicans | 66-kDa subunit | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human buccal epihelial cells (BECs) | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8005674 |
| Candida albicans | "Extracellular polymeric material, acid proteinase, chitin" | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human buccal epihelial cells (BECs) | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 8005674 |
| Influenza virus | Residues 226 (glutamine) and 228 (glycine) | Sialic acid linked to α2,3Galβ1,3GalNAc | Oligosaccharides | Avian/equine isolates | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 7975212 |
| Influenza virus | Residues 226 (leucine) and 228 (serine) | Sialic acid α2,6Galβ1,4GalNAc | Oligosaccharides | Human isolates | NeuAc(a2-6)Gal(b1-4)GalNAc | Binding | 7975212 |
| Streptococcus suis | Adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Erythrocytes | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7961660 |
| Streptococcus suis | Adhesins | P1 antigen (GSL) | Glycosphingolipids | Gal(a1-4)Gal | Binding | 7961660 | |
| Streptococcus suis | Adhesins | Gb3 (Globotriaosylceramide; Trihexosylceramide; Pk antigen (GSL); CTH) | Oligoglycosylceramides | Erythrocytes | Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7961660 |
| Streptococcus suis | Adhesins | Gb2 (Galabiosylceramide) | Diosylceramides | Gal(a1-4)Gal(b1-1)Cer | Binding | 7961660 | |
| Escherichia coli | Fimbrial lectin (adhesin) protein GafD (25-kDa) | N-Acetylglucosamine | Monosaccharides | GlcNAc | Binding | 7883703 | |
| Influenza virus | Unknown | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Influenza virus | Unknown | GD3(Neu5Ac9Ac) | Disialoglycosphingolipids | Ac(-9)NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Influenza virus | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Influenza virus | Unknown | GM1b | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Influenza virus | Unknown | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Influenza virus | Unknown | NeuAc3-Lc4Cer (Sialyl lactotetraosylceramide) | Sialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Influenza virus | Unknown | GT1b | Trisialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Influenza virus | Unknown | GD3(Neu5Ac9Ac) | Disialoglycosphingolipids | Ac(-9)NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Influenza virus | Unknown | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Influenza virus | Unknown | GM3(NeuGc) | Monosialoglycosphingolipids | NeuGc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Influenza virus | Unknown | Sialyl-6-Paragloboside (S-6-PG; α2,6-sialylparagloboside) | Monosialoglycosphingolipids | NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Influenza virus | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Influenza virus | Unknown | GM1b | Monosialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Influenza virus | Unknown | I-active ganglioside | Sialoglycosphingolipids | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 | |
| Influenza virus | Unknown | NeuAc6-Lc4Cer (Sialyl lactotetraosylceramide) | Sialoglycosphingolipids | NeuAc(a2-6)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 7870741 |
