Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Source Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Displaying entries 1801 - 1825 of 1840 in total
Species Pathogen Adherence Molecule Ligand Name ▲ Ligand Feature Target Source Glycan Sequence Binding PubMed ID
Actinomyces naeslundii Unknown unnamed ligand Oligoglycosylceramides Various sources Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer Not Binding 2358461
Actinomyces naeslundii Unknown unnamed ligand Oligoglycosylceramides Various sources GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer Not Binding 2358461
Shigella dysenteriae B subunit unnamed ligand Polyglycosylceramides Rat small intestine GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 Not Binding 3543013
Shigella dysenteriae Shiga toxin unnamed ligand Oligoglycosylceramides [Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=2-5 Not Binding 2435422
Shigella dysenteriae Unknown unnamed ligand Oligoglycosylceramides [Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=2-5 Not Binding 2435422
Shigella dysenteriae Shiga toxin unnamed ligand Polyglycosylceramides GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 Not Binding 2435422
Shigella dysenteriae Unknown unnamed ligand Polyglycosylceramides GalNAc(b1-3)[Gal(a1-3)]nGal(a1-4)Gal(b1-4)Glc(b1-1)Cer *n=1-5 Not Binding 2435422
Staphylococcus haemolyticus 17-kDa HBP (Heparin-binding protein) von Willebrand factor (VWF) Glycoproteins Binding 11393292
Staphylococcus epidermidis 17-kDa HBP (Heparin-binding protein) von Willebrand factor (VWF) Glycoproteins Binding 11393292
Clostridium difficile Toxin A α-Gal on Fab of IgA(κ) MAb Glycoproteins Mouse Gal Binding 9573079
Clostridium difficile Unknown α-Gal on Fab of IgA(κ) MAb Glycoproteins Mouse Gal Binding 9573079
Clostridium difficile Toxin A α-Gal on Fab of IgM(λ) MAb Glycoproteins Mouse Gal Binding 9573079
Clostridium difficile Unknown α-Gal on Fab of IgM(λ) MAb Glycoproteins Mouse Gal Binding 9573079
Listeria monocytogenes Unknown α-GalCer/CD1d tetramers Glycoconjugates V[alpha]14+ NK1.1- T cells in infected liver of mice Binding 16988270
Escherichia coli S-fimbriae α-Sialyl-2,3-lactose-containing receptors Saccharides Binding 11401961
Shigella dysenteriae B subunit α-hydroxylated Gb3 Oligoglycosylceramides Binding 3519828
Equine rhinitis A virus Viral protein α-mannose and α-glucose side chains of ConA-binding glycoproteins Glycoproteins Feline kidney(CRFK)/Equine fetal kidney(EFK)/Mouse(McCoy)/Rabbit kidney(RK-13) Man/Glc Binding 15302947
Escherichia coli SafS α-sialyl-2-3-β-galactose Disaccharides Binding 12640357
Foot-and-mouth disease virus VP1 protein (RGD motif) αvβ3 Integrin Glycoproteins BHK-21/LLC-MK2/HeLa/BK-LF Binding 7533862
Foot-and-mouth disease virus VP1 (RGD peptide) αvβ3 Integrin (independent of expression of Heparan sulfate on cell-sulface) Glycoproteins Extracellular matrix (ECM) Binding 9557639
Foot-and-mouth disease virus RGD motif of the VP1 GH loop αvβ6 Integrin Glycoproteins Epithelial cells Binding 10799568
Entamoeba histolytica Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa). β-2 and β-7 integrins Glycoproteins Intestinal cells Binding 15322032
Entamoeba histolytica Raft-like plasma membrane domains β-2 and β-7 integrins Glycoproteins Intestinal cells Binding 15322032
Escherichia coli Type 1-fimbriae β-D-glycosides Glycoconjugates Patient with urinary tract infection Binding 6138149
Clostridium difficile Toxin A β-Gal on Fab of IgG3(λ) MAb Glycoproteins Mouse Gal Binding 9573079

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