GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **451 - 475** of **557** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Scavenging of heme from plasma	Albumin Hemoglobin subunit alpha Hemoglobin subunit beta Hemopexin LDL receptor related protein 1 Scavenger receptor cysteine-rich type 1 protein M130	A0A140T897 A0A452DI25 E1BGJ0 P01966 P02070 P85521	ALB CD163 HBA HBB HPX LRP1 M130	Bos taurus (cattle)
Sema3A PAK dependent Axon repulsion	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta LIM domain kinase 1 Neuropilin Plexin A1 Plexin A2 Plexin A3 Plexin A4 Semaphorin 3A Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase non-specific serine/threonine protein kinase	A0A3Q1LSY0 A0A3Q1M0G8 A0JNB0 E1BC64 E1BFR4 E1BMX5 F1MEW1 F1MIH8 F1N173 F1N2P7 Q08E52 Q5E9H3 Q76LV1 Q76LV2	FES FYN HSP90A HSP90AA1 HSP90AB1 HSPC3 HSPCA HSPCB LIMK1 NRP1 PAK1 PAK2 PAK3 PLXNA1 PLXNA2 PLXNA3 PLXNA4 SEMA3A	Bos taurus (cattle)
Sensory perception of salty taste	Amiloride-sensitive sodium channel subunit alpha Amiloride-sensitive sodium channel subunit beta Amiloride-sensitive sodium channel subunit gamma Sodium channel epithelial 1 subunit delta	A5D7U4 F1MJW3 F1MY57 P55270	SCNN1A SCNN1B SCNN1D SCNN1G	Bos taurus (cattle)
Sensory perception of sweet, bitter, and umami (glutamate) taste	G protein subunit beta 3 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(t) subunit alpha-3 Inositol 1,4,5-trisphosphate receptor Taste 1 receptor member 1 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2	A0A3Q1LRA2 A0A3Q1LZA1 A0A3Q1MIP5 A0A3Q1ML22 A0A3Q1N0Q7 A0A3Q1NGS8 A0A3Q1NND8 E1B8B7 E1B8Q3 E1BKE7 E1BPM8 F1MP17 F1MVK0 F1N5V2 P0C7Q4 P62871 Q2ABB3 Q2ABC0 Q2ABC3 Q2ABC4 Q2ABC5	GNAT3 GNB1 GNB3 GNG13 ITPR3 LOC782957 T2R10C TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R16 TAS2R3 TAS2R39 TAS2R4 TAS2R40 TAS2R46 TAS2R7 TAS2R8	Bos taurus (cattle)	G58161NS
Separation of Sister Chromatids	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 AT-hook containing transcription factor 1 Alpha isoform of regulatory subunit A, protein phosphatase 2 Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 Aurora kinase B9 domain-containing protein 2 BUB1 mitotic checkpoint serine/threonine kinase B BUB1 protein Baculoviral IAP repeat-containing protein 5 Borealin CAP-Gly domain containing linker protein 1 CENPI protein CENPP protein Cell division cycle 16 Cell division cycle 20 Cell division cycle associated 5 Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog Centromere protein C Centromere protein E Centromere protein F Centromere protein H Centromere protein K Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein Q Centromere protein S Centromere protein T Cohesin subunit SA Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic linker associated protein 1 Cytoplasmic linker associated protein 2 Cytoskeleton associated protein 5 DNA excision repair protein ERCC-6-like DSN1 component of MIS12 kinetochore complex Double-strand-break repair protein rad21 homolog Dynein cytoplasmic 1 heavy chain 1 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Dynein light intermediate chain Dynein light intermediate chain E2 ubiquitin-conjugating enzyme Exportin 1 Histone H3-like centromeric protein A Histone deacetylase 8 Inner centromere protein Integrin subunit beta 3 binding protein Kinesin-like protein Kinetochore associated 1 Kinetochore protein NDC80 Kinetochore protein Spc24 Kinetochore protein Spc25 Kinetochore scaffold 1 Microtubule-associated protein RP/EB family member 1 Mitotic arrest deficient 1 like 1 Mitotic arrest deficient 2 like 1 Mitotic checkpoint protein BUB3 NDE1 protein NSL1 protein NUF2 component of NDC80 kinetochore complex NUP43 protein Nuclear distribution protein nudE-like 1 Nuclear migration protein nudC Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup98-Nup96 Nuclear pore complex protein Nucleoporin 133 Nucleoporin 160 Nucleoporin 37 Nucleoporin SEH1 PDS5 cohesin associated factor A PDS5 cohesin associated factor B Platelet-activating factor acetylhydrolase IB subunit alpha Polyamine-modulated factor 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Protein MIS12 homolog Protein SEC13 homolog Protein Spindly Protein phosphatase 2 scaffold subunit Abeta Protein zwilch homolog RAN binding protein 2 RCC2 protein Ran GTPase activating protein 1 STAG1 cohesin complex component Serine/threonine-protein kinase PLK1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform Serine/threonine-protein phosphatase PP1-gamma catalytic subunit Shugoshin 1 Shugoshin 2 Small ribosomal subunit protein eS27 Spindle and kinetochore-associated protein 1 Spindle and kinetochore-associated protein 2 Structural maintenance of chromosomes protein 1A Structural maintenance of chromosomes protein Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WAPL cohesin release factor ZW10 interacting kinetochore protein ZW10, kinetochore associated, homolog (Drosophila) non-specific serine/threonine protein kinase separase	A0A3Q1LLS4 A0A3Q1LQI2 A0A3Q1LTH6 A0A3Q1M302 A0A3Q1M6A8 A0A3Q1M862 A0A3Q1MAP0 A0A3Q1MAR8 A0A3Q1MDJ2 A0A3Q1MMV9 A0A3Q1MQQ6 A0A3Q1MWV1 A0A3Q1NEK5 A0A3Q1NEU9 A0A452DI44 A0A452DIY4 A1A4R8 A2VDZ0 A3KMW1 A4FV68 A4IFM5 A5D7P3 A5D973 A6H7B3 A6QL85 A6QLS4 A6QLW0 A6QM04 A6QPS5 A6QQ16 A6QQ81 A6QQR4 A7MBA2 A7YWP8 A7YY75 A7Z061 A7Z065 E1B7K5 E1B945 E1BAB6 E1BAK5 E1BBQ0 E1BCV4 E1BD42 E1BD83 E1BDU0 E1BE98 E1BF82 E1BG49 E1BGC3 E1BJ19 E1BK11 E1BKG4 E1BLA0 E1BM34 E1BPM5 E1BQ15 F1MBI1 F1MBQ0 F1MC39 F1MFD5 F1MGX8 F1MLG9 F1MLV1 F1MM55 F1MNP7 F1MQN0 F1MR95 F1MRW5 F1MT24 F1MUQ7 F1MW01 F1MWE0 F1MWP1 F1MWW9 F1MXE4 F1MYH8 F1MZR0 F1N0Y3 F1N1F8 F1N1S8 F1N6Z0 F1N7G8 F1N7G9 F2Z4G9 G3MX31 G3MXW4 G3N1P6 G3N2Y5 G3X6R3 G5E589 G5E613 O97593 P0CG53 P0CH28 P33672 P56701 P61285 P61287 P62194 P62992 P63048 P67774 Q08DN4 Q08DP7 Q08DW5 Q0P594 Q0P5L6 Q17QG2 Q17QP9 Q1JQB2 Q1RML1 Q29RQ3 Q2KHT7 Q2KI42 Q2KII9 Q2KJ25 Q2KJ46 Q2KJE7 Q2T9N4 Q2TA10 Q2TA25 Q2TBH1 Q2TBR7 Q2YDE4 Q32KL2 Q32PA5 Q3MHN0 Q3MHR3 Q3SWX9 Q3SX30 Q3SZ19 Q3SZ31 Q3SZC2 Q3SZT7 Q3T030 Q3T0L1 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBD9 Q3ZBG0 Q3ZBK3 Q3ZBK8 Q3ZC98 Q3ZCC9 Q3ZCF6 Q3ZCK9 Q58DR0 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0 Q5EA18 Q5EA49 Q6J1J1	AHCTF1 ANAPC1 ANAPC10 ANAPC11 ANAPC15 ANAPC16 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANAPC8 APITD1 AURKB B9D2 BIRC5 BUB1 BUB1B BUB3 CCDC99 CDC16 CDC20 CDC23 CDC26 CDC27 CDCA5 CDCA8 CENPC CENPE CENPF CENPH CENPI CENPK CENPL CENPM CENPO CENPP CENPQ CENPS CENPT CKAP5 CLASP1 CLASP2 CLIP1 DNCL1 DSN1 DYNC1H1 DYNC1I1 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 ERCC6L ESPL1 FAAP16 HDAC8 INCENP ITGB3BP KIF2B KNL1 KNTC1 LIS1 MAD1L1 MAD2L1 MAPRE1 MCM21R MHF1 MIS12 NDC80 NDE1 NDEL1 NSL1 NUDC NUF2 NUP107 NUP133 NUP160 NUP37 NUP43 NUP85 NUP98 PAFAH1B1 PDS5A PDS5B PLK1 PMF1 PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5D PPP2R5E PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RAD21 RANBP2 RANGAP1 RCC2 RPS27 RPS27A SCC1 SEC13 SEC13L1 SEH1L SGO1 SGO2 SKA1 SKA2 SMC1 SMC1A SMC1L1 SMC3 SPBC25 SPC24 SPC25 SPDL1 STAG1 STAG2 SUG1 TAOK1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBCH10 UBE2C UBE2D1 UBE2E1 UBE2S WAPL XPO1 ZW10 ZWILCH ZWINT	Bos taurus (cattle)
Serine biosynthesis	D-3-phosphoglycerate dehydrogenase Phosphoserine aminotransferase Phosphoserine phosphatase Serine incorporator 1 Serine incorporator 2 Serine incorporator 3 Serine incorporator 4 Serine incorporator 5 Serine racemase	A0A140T866 A0A3Q1LF32 A0A3S5ZPF7 A0JNI4 A4FUZ5 F1MGF0 Q2KHU0 Q3MHV9 Q58CW5	PHGDH PSAT1 PSPH SERINC1 SERINC2 SERINC3 SERINC4 SERINC5 SRR TDE2 TDE2L	Bos taurus (cattle)
Serotonin Neurotransmitter Release Cycle	Complexin-1 PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 PTPRF interacting protein alpha 3 PTPRF interacting protein alpha 4 Ras-related protein Rab-3A Regulating synaptic membrane exocytosis 1 Solute carrier family 18 (Vesicular monoamine), member 2 Synapsin-1 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-1A Syntaxin-binding protein 1 Unc-13 homolog B Vesicle-associated membrane protein 2	A0A3Q1LQ22 A0A3Q1LZT1 A0A3Q1M5L6 A0A3Q1MBH3 B0JYP2 E1BIA1 F1MCX7 F1N7B7 P11023 P32850 P48018 P61763 P63026 Q0IIL7 Q17QQ3	CPLX1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RIMS1 SLC18A2 SNAP25 STX1A STXBP1 SYB2 SYN1 SYT1 UNC13B UNC18A VAMP2	Bos taurus (cattle)
Sialic acid metabolism	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase Beta-galactosidase Beta-galactoside alpha-2,6-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase Carboxypeptidase Gal-NAc6S Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Lactosylceramide alpha-2,3-sialyltransferase N-acetylneuraminate lyase N-acetylneuraminate synthase N-acetylneuraminic acid phosphatase N-acylneuraminate cytidylyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 Sialidase-1 Solute carrier family 17 member 5 Solute carrier family 35 (CMP-sialic acid transporter), member A1 Type 2 lactosamine alpha-2,3-sialyltransferase alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase	A0A3Q1LM08 A0A3Q1LRX1 A0A3Q1LUC6 A0A3Q1LZS9 A0A3Q1MGH3 A0A3Q1N8K2 A0A3Q1NDQ7 A0A452DJ87 A0A452DJH9 A5D7T4 A5D960 A6BMK7 A7YWM8 E1B7R3 E1BMN0 F1MIL9 F1MRJ3 F1MVI9 F1MXN8 F1N2J4 F1N6V7 F1N7G6 G3N3B2 G5E5Q1 Q1RMX7 Q29RY9 Q3SZM5 Q3SZP1 Q6H8M7 Q6H8M9	CMAS CTSA GLB1 GNE NANP NANS NEU1 NEU2 NEU3 NEU4 NPL SIAT10 SLC17A5 SLC35A1 ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL5 ST3GAL6 ST6GAL2 ST6GALNAC1 ST6GALNAC2 ST6GALNAC4 ST6GALNAC5 ST6GALNAC6 ST8SIA1 ST8SIA2 ST8SIA3 ST8SIA4 ST8SIA5 siat4B	Bos taurus (cattle)
Signaling by Activin	Activin receptor type-2A Inhibin alpha chain Inhibin beta A chain Inhibin beta B chain Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Serine/threonine-protein kinase receptor Transforming growth factor beta receptor 3 receptor protein serine/threonine kinase receptor protein serine/threonine kinase	A0A3Q1LMU4 A0A3Q1MGJ6 B0JYL0 E1B8P9 E1B9H5 E1BE92 F1MMW7 F1MSQ2 F1MUZ3 P07994 P07995 P46196 Q28043	ACTRII ACVR1B ACVR1C ACVR2 ACVR2A ACVR2B ERK2 INHA INHBA INHBB MAPK1 MAPK3 PRKM1 SMAD2 SMAD3 SMAD4 TGFBR3	Bos taurus (cattle)
Signaling by BMP	Activin receptor type-2A Anti-Muellerian hormone type-2 receptor Bone morphogenetic protein 2 Bone morphotic protein 10 Cerberus 1, DAN family BMP antagonist Chordin like 1 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Follistatin-related protein 1 Growth differentiation factor 2 Inhibin alpha chain Inhibin beta A chain Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Muellerian-inhibiting factor Noggin Serine/threonine-protein kinase receptor Serine/threonine-protein kinase receptor Ski oncogene Transforming growth factor beta receptor 3 Ubiquitin conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 D1 Zinc finger FYVE-type containing 16 receptor protein serine/threonine kinase receptor protein serine/threonine kinase receptor protein serine/threonine kinase	A0A3Q1LJ39 A0A3Q1LP90 A0A3Q1LSA1 A0A3Q1M3K3 A0A3Q1M5N0 A0A3Q1MGJ6 A5PJI9 B0JYL0 E1B8T7 E1B8X7 E1B9H5 E1BBN3 E1BEG4 E1BG11 E1BH37 E1BHR7 E1BN54 F1MAZ4 F1MCE7 F1MIW7 F1MLS5 F1MZL1 F1N727 G3N3L0 P07994 P07995 Q1JQA2 Q28043 Q2TA10 Q58D84	ACTRII ACVR2 ACVR2A ACVR2B ACVRL1 AMH AMHR2 BMP10 BMP2 BMPR1A BMPR1B BMPR2 CER1 CHRDL1 FSTL1 GDF2 INHA INHBA NOG SF3A2 SKI SMAD1 SMAD4 SMAD5 SMAD6 SMAD7 SMAD9 SMURF1 SMURF2 TGFBR3 UBE2D1 UBE2D3 ZFYVE16	Bos taurus (cattle)
Signaling by CSF3 (G-CSF)	Colony stimulating factor 3 receptor GRB2 associated binding protein 2 Granulocyte colony-stimulating factor Growth factor receptor-bound protein 2 SHC-transforming protein 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type small monomeric GTPase	A0A3Q1M864 A0A3Q1MHG9 A0A3Q1MYA3 E1B9W2 E1BCP6 E1BMX0 F1MCX4 F1N0D6 F1N261 F1N339 P35833 Q0IIE2 Q3T0F9	CSF3 CSF3R GAB2 GCSF GRB2 JAK1 JAK2 KRAS LYN PTPN11 SHC1 SRC SYK TYK2	Bos taurus (cattle)
Signaling by ERBB4	Betacellulin Epiregulin Neuregulin 2 Neuregulin 3 Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase	A0A3Q1MKB4 A2VE27 A6QR62 E1BBE2 E1BIN8 F1MPD0 F1MS28 G3N104	BTC ERBB3 ERBB4 EREG HBEGF NRG1 NRG2 NRG3	Bos taurus (cattle)
Signaling by Erythropoietin	Erythropoietin receptor Insulin receptor substrate 2 Tyrosine-protein kinase Tyrosine-protein kinase	E1BCP6 F1MEQ7 F1MJE0 F1N261	EPOR IRS2 JAK2 LYN	Bos taurus (cattle)
Signaling by Insulin receptor	Insulin Tyrosine-protein kinase receptor	A5PJB2 F1MV64	INS INSR	Bos taurus (cattle)
Signaling by PDGF	Collagen alpha-1(IV) chain Collagen type VI alpha 1 chain Collagen type VI alpha 2 chain Collagen type VI alpha 3 chain Collagen type VI alpha 5 chain Collagen type VI alpha 6 chain Plasminogen activator Plasminogen Platelet-derived growth factor C Platelet-derived growth factor D Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Secreted phosphoprotein 1 Thrombospondin 1 Thrombospondin 2 Thrombospondin 3 Thrombospondin 4 furin protein-tyrosine-phosphatase	A0A3Q1LXW3 A0A3Q1LZU0 A0A3Q1M0B4 A0A3Q1ME99 A0A3Q1MQV3 A0A3Q1MQX0 A0A3Q1N3Z8 A0A452DIF6 A0A452DJ62 A4IFC0 B0JYR0 B1H0W5 E1B726 E1BB91 E1BI98 E1BJY4 F1MD40 F1MKG2 F1N1W3 Q2KJ15 Q7SIB2	COL4A1 COL6A1 COL6A2 COL6A3 COL6A5 COL6A6 FURIN PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PLAT PLG PTPN12 SPP1 THBS1 THBS2 THBS3 THBS4	Bos taurus (cattle)
Signaling by ROBO receptors	C-X-C chemokine receptor type 4 Glypican-1 Roundabout guidance receptor 1 Slit guidance ligand 2 Slit guidance ligand 3 Stromal cell-derived factor 1	A0A3Q1LZ29 A0A3Q1M085 F1MLJ7 F1MMM6 F1N739 P25930	CXCL12 CXCR4 GPC1 ROBO1 SLIT2 SLIT3	Bos taurus (cattle)
Signaling by SCF-KIT	GRB2 associated binding protein 2 GRB2 related adaptor protein 2 GRB2-related adapter protein GTPase NRas Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Kit ligand Mast/stem cell growth factor receptor Matrix metalloproteinase-9 Peptidase S1 domain-containing protein Peptidase S1 domain-containing protein Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3 Proto-oncogene vav SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type protein-tyrosine-phosphatase small monomeric GTPase	A0A140T878 A0A3Q1LNN8 A0A3Q1M864 A0A3Q1ME65 A0A452DHX3 A0JNB0 A5D7R9 A6QLK6 A7MB57 E1B8U1 E1BCP6 E1BIM8 E1BIP7 E1BKA6 E1BMX0 E1BNE0 F1MD22 F1MDQ5 F1MSH3 F1MX38 F1N261 F1N339 F1N7C3 P23726 P23727 P32871 P52176 Q08DN7 Q1RMW5 Q28132 Q3T0F9 Q3ZCM0 Q5E9H3 Q95115	FER FES FYN GAB2 GRAP GRAP2 GRB10 GRB2 GRB7 JAK2 KIT KITLG KRAS LCK LOC100139881 LOC540321 LYN MGF MMP9 NRAS PIK3CA PIK3R1 PIK3R2 PIK3R3 PTPN11 PTPRU SCF SOS1 SRC STAT1 STAT3 STAT5A STAT5B TEC VAV1 YES1	Bos taurus (cattle)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	G1K218 P07455 P07456	IGF1 IGF1R IGF2	Bos taurus (cattle)
Sphingolipid catabolism	Aldehyde dehydrogenase family 3 member A2 Aldehyde dehydrogenase family 3 member B1 Alkaline ceramidase Alkaline ceramidase Alkaline ceramidase Phospholipid phosphatase 1 Phospholipid phosphatase 2 Phospholipid phosphatase 3 Sphingosine-1-phosphate phosphatase 1 sphinganine-1-phosphate aldolase	A0A3Q1LJ52 A0A3Q1LM94 A0A3Q1MIK4 A0JNA1 A7MBH7 E1B8N2 F1MGH9 Q1JPA0 Q2HJ61 Q3SZE3	ACER1 ACER2 ACER3 ALDH3A2 ALDH3B1 PLPP1 PLPP2 PLPP3 PPAP2B PPAP2C SGPL1 SGPP1	Bos taurus (cattle)
Sphingolipid de novo biosynthesis	Broad substrate specificity ATP-binding cassette transporter ABCG2 CYB5B protein Ceramide synthase 1 Ceramide synthase 2 Ceramide synthase 3 Ceramide synthase 4 Ceramide synthase 5 Ceramide synthase 6 Ceramide transfer protein Fatty acid 2-hydroxylase MFSD2 lysolipid transporter B, sphingolipid Multidrug resistance-associated protein 1 ORM1-like protein 1 ORM1-like protein 2 ORM1-like protein 3 Oxysterol-binding protein Phosphatidylcholine Protein phosphatase, Mg2+/Mn2+ dependent 1L SPTLC2 protein Serine palmitoyltransferase 1 Serine palmitoyltransferase small subunit A Serine palmitoyltransferase small subunit B Serine/threonine-protein kinase Serine/threonine-protein kinase Serine/threonine-protein kinase Sphingolipid delta(4)-desaturase DES1 Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 Sphingomyelin synthase 2 Sphingosine kinase 1 Sphingosine kinase 2 Sterile alpha motif domain containing 8 Vesicle-associated membrane protein-associated protein A Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase	A0A3Q1MBG6 A0A3Q1MJ30 A0A3Q1MVP2 A0A3Q1N9F5 A0A452DJG0 A2VDZ9 A4FUG2 A5D7K4 A5PKM3 A7MB90 B2D1N9 E1B7L9 E1B7T6 E1BGC2 E1BNX6 E1BPW1 F1MF31 F1MIA2 F1MXZ6 F1MYS1 Q0II71 Q0IIK4 Q0P5F6 Q0VCY1 Q0VD15 Q29RQ9 Q3MHG1 Q3ZBF8 Q3ZBY7 Q5E972 Q5E978 Q5E9R6 Q8HXQ5 Q9GKI7	ABCC1 ABCG2 ADMP CERS1 CERS2 CERS3 CERS4 CERS5 CERS6 CERT CERT1 COL4A3BP CSNK1G2 CYB5B DEGS1 DEGS2 DES1 FA2H LASS1 LASS2 LASS3 LASS4 MFSD2B MRP1 ORMDL1 ORMDL2 ORMDL3 OSBP PPM1L PRKD1 PRKD2 PRKD3 SAMD8 SGMS1 SGMS2 SPHK1 SPHK2 SPTLC1 SPTLC2 SPTSSA SPTSSB SSSPTA SSSPTB STARD11 VAPA VAPB	Bos taurus (cattle)
Stabilization of p53	Cellular tumor antigen p53 Checkpoint kinase 2 E3 ubiquitin-protein ligase Mdm2 Serine-protein kinase ATM	E1BEI6 F1MYE6 F6R5E4 P67939	ATM CHEK2 MDM2 TP53	Bos taurus (cattle)
Stimuli-sensing channels	Acid sensing ion channel subunit 1 Acid sensing ion channel subunit family member 4 Acid sensing ion channel subunit family member 5 Amiloride-sensitive cation channel 1, neuronal Amiloride-sensitive sodium channel subunit alpha Amiloride-sensitive sodium channel subunit beta Amiloride-sensitive sodium channel subunit gamma Anoctamin-4 Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Aspartyl/asparaginyl beta-hydroxylase Bestrophin-2 Bestrophin Bestrophin Bestrophin Calcium-activated chloride channel regulator 1 Calmodulin-like Chloride channel accessory 4 Chloride channel protein 2 Chloride channel protein Chloride channel protein Chloride channel protein Chloride intracellular channel 2 Chloride voltage-gated channel 1 EF-hand domain-containing protein H(+)/Cl(-) exchange transporter 7 Osteoclastosis associated transmembrane protein 1 Peptidyl-prolyl cis-trans isomerase FKBP1B Protein tweety homolog Protein tweety homolog Protein tweety homolog Ryanodine receptor 2 STOM protein Sodium channel epithelial 1 subunit delta Sodium leak channel, non-selective Solute carrier family 17 (Sodium phosphate), member 3 Solute carrier family 9 member B2 Solute carrier family 9, subfamily B (cation proton antiporter 2), member 1 Sorcin Stomatin like 3 Two pore segment channel 1 Two pore segment channel 2 Unc-79 homolog, NALCN channel complex subunit Unc-80 homolog, NALCN channel complex subunit Uncharacterized protein	A0A3Q1LL71 A0A3Q1LNC2 A0A3Q1LUZ5 A0A3Q1M2M7 A0A3Q1M2Y5 A0A3Q1MHC3 A0A3Q1MQ38 A0A3Q1MR28 A0A3Q1MUE0 A0A3Q1N2G9 A1A4I7 A2VE46 A5D7U4 A6QLE6 A6QNR5 A7YWH0 A8E4P3 E1B792 E1BF86 E1BF90 E1BFC4 E1BFF1 E1BHV1 E1BJF8 E1BK15 E1BLQ0 E1BMN1 F1MCB3 F1MFR7 F1MGK7 F1MGZ5 F1MJ95 F1MJW3 F1MLH6 F1MN45 F1MPC2 F1MTH0 F1MX70 F1MY57 F1N0S4 F6QQY9 G3N0G4 G3N3A9 P55270 P68107 Q0VC38 Q17QE9 Q28056 Q3SYU0 Q4PKH3	ACCN1 ANO10 ANO2 ANO3 ANO4 ANO5 ANO6 ANO8 ANO9 ASIC1 ASIC2 ASIC4 ASIC5 ASPH BEST1 BEST2 BEST3 BEST4 CALM CLCA1 CLCA4 CLCN1 CLCN2 CLCN3 CLCN5 CLCN6 CLCN7 CLCNKA CLIC2 FKBP12.6 FKBP1B NALCN NHEDC1 OSTM1 RYR2 SCNN1A SCNN1B SCNN1D SCNN1G SLC17A3 SLC9B2 SRI STOM STOML3 TMEM16D TPCN1 TPCN2 TTYH1 TTYH2 TTYH3 UNC79 UNC80	Bos taurus (cattle)
Striated Muscle Contraction	Alpha-actinin-2 Alpha-actinin-3 Desmin Dystrophin MYBPC1 protein MYH3 protein Myosin heavy chain 8 Myosin light chain 1/3, skeletal muscle isoform Myosin regulatory light chain 2, ventricular/cardiac muscle isoform Myosin, light chain 4, alkali; atrial, embryonic Myosin-6 Myosin-binding protein C, cardiac-type Nebulin Telethonin Tropomodulin 2 Tropomodulin 3 Tropomodulin-1 Tropomodulin-4 Tropomyosin alpha-1 chain Tropomyosin alpha-3 chain Tropomyosin beta chain Troponin C, skeletal muscle Troponin C, slow skeletal and cardiac muscles Troponin I, fast skeletal muscle Troponin I1, slow skeletal type Troponin T, cardiac muscle Troponin T, fast skeletal muscle Troponin T, slow skeletal muscle Vimentin	A0A3Q1LL62 A0A3Q1LVZ9 A0A3Q1M1N1 A0A3Q1M4Y0 A0A3Q1MC60 A0A3Q1N6P5 A0A452DJI6 A0JNC0 A0JNJ5 A6QP89 A6QPA6 E1BAI7 F1N2G0 F6QIC1 G3MYN5 G3MZK7 G3N264 O62654 P48616 P63315 Q0III9 Q0VC48 Q1RMM7 Q3ZC55 Q5KR47 Q5KR48 Q5KR49 Q6T8D8 Q8MKH6	ACTN2 ACTN3 DES DMD MYBPC1 MYBPC3 MYH3 MYH6 MYH8 MYL1 MYL2 MYL4 NEB TCAP TMOD1 TMOD2 TMOD3 TMOD4 TNNC TNNC1 TNNC2 TNNI1 TNNI2 TNNT1 TNNT2 TNNT3 TPM1 TPM2 TPM3 VIM	Bos taurus (cattle)
Surfactant metabolism	ATP binding cassette subfamily A member 3 Adenosine receptor A2 Adenosine receptor A2b Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor BoWC1.1 CD163 molecule-like 1 Cytoskeleton associated protein 4 GATA binding protein 6 LIM and cysteine-rich domains protein 1 Napsin A aspartic peptidase P2Y purinoceptor 2 Palmitoyltransferase Pepsin A Pro-cathepsin H Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein C Pulmonary surfactant-associated protein D SRCR domain-containing protein SRCR domain-containing protein SRCR domain-containing protein Sodium-dependent phosphate transport protein 2A Surfactant protein A1 Thyroid transcription factor 1-associated protein 26 Transcription termination factor 1 WC1 isolate CH149 WC1 isolate DV10 WC1.3 molecule adenosine deaminase	A0A3Q1LQ48 A0A3Q1LVH8 A0A3Q1MC87 A0A3Q1MPU0 A0A3Q1MQ71 A0A3Q1NJ66 A0A3Q1NNS6 A0A452DJB4 A5PJN1 E1B813 E1B9V4 E1BCR1 E1BJW6 E1BKU0 E3W9A0 F1MBC6 F1MDI7 F1ME65 F1MV32 F1N144 F1N1M2 F1N373 G3MXF3 G3X8C9 P15781 P35246 Q17QE2 Q1LZD0 Q28838 Q3T0I2	ABCA3 ADA2 ADGRF5 ADORA2A ADORA2B ADRA2A ADRA2C CCDC59 CD163L1 CKAP4 CTSH GATA6 LMCD1 LOC101907335 LOC751811 LOC786796 NAPSA P2RY2 PGA5 SFTP3 SFTP4 SFTPA1 SFTPB SFTPC SFTPD SLC34A1 TAP26 TTF1 WC-7 WC1 WC1-12 WC1.3 ZDHHC2	Bos taurus (cattle)
Switching of origins to a post-replicative state	Chromatin licensing and DNA replication factor 1 DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 GMNN protein	A0A3Q1LHC9 A0A3Q1LIW5 A4FUD9 A6H7F8 E1BFZ9 E1BH89 Q3ZBH9 Q56JZ0	CDT1 GMNN MCM2 MCM3 MCM4 MCM5 MCM6 MCM7	Bos taurus (cattle)

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