GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **476 - 500** of **557** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Synaptic adhesion-like molecules	Discs large MAGUK scaffold protein 3 Discs large MAGUK scaffold protein 4 Disks large homolog 1 Flotillin-1 Flotillin-2 Glutamate receptor Glutamate receptor Leucine rich repeat and fibronectin type III domain containing 1 Leucine rich repeat and fibronectin type III domain containing 2 Leucine rich repeat and fibronectin type III domain containing 4 Leucine-rich repeat and fibronectin type-III domain-containing protein 3 Receptor-type tyrosine-protein phosphatase F protein-tyrosine-phosphatase protein-tyrosine-phosphatase	A0A3Q1LQB5 A0A3Q1M422 A0A3Q1MBH0 A0A3Q1MFJ1 A0A3Q1MZF8 A6QLR4 A7MBJ4 E1BDP0 F1MJL8 F1MM66 G0T3G6 G3MZS2 Q08DN8 Q1RMS4	DLG1 DLG3 DLG4 FLOT1 FLOT2 GRIA1 GRIA3 LRFN1 LRFN2 LRFN3 LRFN4 PTPRD PTPRF PTPRS SALM4	Bos taurus (cattle)
Syndecan interactions	Fibroblast growth factor 2 Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 2 Integrin subunit alpha 6 Integrin subunit alpha V Syndecan-1 Syndecan-2 Syndecan Transforming growth factor beta-1 proprotein Vitronectin	A0A140T8D2 A0A3Q1M8K4 A0A3Q1MRM3 A0A3Q1MXS2 A0A3Q1N449 E1BKS1 F1MBA3 F1MTN1 P03969 Q08DZ5 Q3ZBS7 Q58DD4 Q8SQB9	FGF2 ITGA2 ITGA6 ITGAV ITGB1 ITGB3 ITGB4 ITGB5 SDC1 SDC2 SDC4 TGFB1 VTN	Bos taurus (cattle)
Synthesis of 12-eicosatetraenoic acid derivatives	Arachidonate 12-lipoxygenase, 12R type Arachidonate 12-lipoxygenase, 12S type Arachidonate lipoxygenase 3 Glutathione peroxidase 1 Phospholipid hydroperoxide glutathione peroxidase Polyunsaturated fatty acid lipoxygenase ALOX15	E1BIT6 F1MFA8 F1MXD8 P00435 P27479 Q9N2J2	ALOX12 ALOX12B ALOX15 ALOXE3 GPX1 GPX4	Bos taurus (cattle)
Synthesis of 5-eicosatetraenoic acids	Arachidonate 5-lipoxygenase-activating protein Arachidonate 5-lipoxygenase Leukotriene C4 synthase Paraoxonase Paraoxonase Serum paraoxonase/arylesterase 2	F1MQ78 Q148F2 Q1JQD3 Q2KIW1 Q2NKS0 Q58DS7	ALOX5 ALOX5AP LTC4S PON1 PON2 PON3	Bos taurus (cattle)
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Calmodulin-like EF-hand domain-containing protein Inositol polyphosphate-5-phosphatase J Inositol-tetrakisphosphate 1-kinase Kinase Kinase Kinase Phosphatase and tensin homolog Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phospholipase C epsilon 1 Phospholipase D family member 4 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase	A0A3Q1LJT8 A0A3Q1LJY0 A0A3Q1LNH2 A0A3Q1MMD9 A0A3Q1MR28 A4FV33 E1BB73 E1BBJ7 E1BJE0 E1BLB5 F1MBY5 F1MDX9 F1MLH6 F1MN32 F1MSD7 F1MTE8 F1MYF9 G3N3D6 P0C0T1 P10894 P10895 Q1RML2	CALM INPP5B INPP5D INPP5J INPPL1 ITPK1 ITPKA ITPKB ITPKC OCRL PLCB1 PLCB4 PLCD1 PLCD3 PLCE1 PLCG1 PLCG2 PLCH1 PLCZ PLCZ1 PLD4 PTEN	Bos taurus (cattle)
Synthesis of Ketone Bodies	Acetoacetyl-CoA synthetase Acetyl-CoA acetyltransferase, mitochondrial Acyl-CoA synthetase short-chain family member 3, mitochondrial D-beta-hydroxybutyrate dehydrogenase, mitochondrial Dehydrogenase/reductase SDR family member 6 Hydroxymethylglutaryl-CoA lyase, mitochondrial Hydroxymethylglutaryl-CoA synthase, mitochondrial hydroxymethylglutaryl-CoA lyase	A7MB45 E1BK37 F1MLA4 F1N412 Q02337 Q29448 Q29RZ0 Q2KIE6	AACS ACAT1 ACSS3 BDH BDH1 BDH2 HMGCL HMGCLL1 HMGCS2	Bos taurus (cattle)
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Arachidonate 5-lipoxygenase-activating protein Arachidonate 5-lipoxygenase CYP4A22 protein Cytochrome P450, family 4, subfamily B, polypeptide 1 Cytochrome P450, family 4, subfamily F, polypeptide 2 Dipeptidase 1 Dipeptidase 3 Dipeptidase Glutathione hydrolase Glutathione hydrolase Leukotriene A-4 hydrolase Leukotriene C4 synthase MAPK activated protein kinase 2 Multidrug resistance-associated protein 1 Phylloquinone omega-hydroxylase CYP4F2-like Polyunsaturated fatty acid lipoxygenase ALOX15 Uncharacterized protein	A0A3Q1M614 A0A3Q1MCJ2 A0A3Q1MU89 A5PK83 E1BDI1 E1BIR2 F1MQ78 F1MYJ3 G3N2D8 M0QW30 P27479 Q148E6 Q148F2 Q2NKS0 Q3SZH7 Q3SZM7 Q8HXQ5	ABCC1 ALOX15 ALOX5 ALOX5AP CYP4A22 CYP4B1 CYP4F2 DPEP1 DPEP2 DPEP3 GGT1 GGT5 LOC100295883 LTA4H LTC4S MAPKAPK2 MRP1	Bos taurus (cattle)
Synthesis of PA	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha 1-acyl-sn-glycerol-3-phosphate acyltransferase delta 1-acyl-sn-glycerol-3-phosphate acyltransferase 1-acylglycerol-3-phosphate O-acyltransferase 3 1-acylglycerol-3-phosphate O-acyltransferase 5 1-acylglycerol-3-phosphate O-acyltransferase 6 (Lysophosphatidic acid acyltransferase, zeta) Cytosolic phospholipase A2 DDHD domain containing 1 DDHD domain containing 2 Dihydroxyacetone phosphate acyltransferase Glycerol-3-phosphate acyltransferase 1, mitochondrial Glycerol-3-phosphate acyltransferase 2, mitochondrial Glycerol-3-phosphate acyltransferase 3 Glycerol-3-phosphate dehydrogenase [NAD(+)] Glycerol-3-phosphate dehydrogenase [NAD(+)] Glycerol-3-phosphate dehydrogenase, mitochondrial LPCAT4 protein Lipase H Lysophosphatidic acid phosphatase type 6 Lysophosphatidylcholine acyltransferase 1 Mitochondrial cardiolipin hydrolase Mitoguardin 1 Mitoguardin 2 PLA2G12A protein Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase Phospholipase Secretory phospholipase A2 receptor alkaline phosphatase	A0A3Q1LQH8 A0A3Q1MFB9 A0A3Q1MFP5 A0A3Q1MMR4 A0A3Q1MNU5 A0A3S5ZPU2 A0A452DJJ3 A0JNE8 A4IFJ5 A5D7L0 A6H757 A6H7D4 A6QLU1 A6QQR7 E1BE10 E1BGF8 E1BGU4 E1BJE3 F1MDT6 F1MG30 F1MLW9 F1MNB3 F1MSG5 F1MSS2 F1MTK4 F1MXA8 F1MZS9 G5E5P6 P00593 P49259 Q1JPG0 Q56JZ2 Q5EA60 Q95JH2	ACP6 AGPAT1 AGPAT2 AGPAT3 AGPAT4 AGPAT5 AGPAT6 CPLA2 DDHD1 DDHD2 FAM73B GNPAT GPAM GPAT2 GPAT3 GPAT4 GPD1 GPD1L GPD2 LIPH LOC516378 LOC613966 LPCAT1 LPCAT4 MIGA1 MIGA2 PLA2G12A PLA2G1B PLA2G2A PLA2G2D1 PLA2G2E PLA2G4 PLA2G4A PLA2G4D PLA2R1 PLD1 PLD2 PLD6	Bos taurus (cattle)
Synthesis of PC	Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta Choline O-acetyltransferase Choline transporter-like protein 2 Choline transporter-like protein 3 Choline transporter-like protein 4 Choline transporter-like protein Choline transporter-like protein Choline/ethanolaminephosphotransferase 1 Cholinephosphotransferase 1 Lysophosphatidylcholine acyltransferase 1 MFSD2 protein Phosphatidylcholine transfer protein Phosphatidylethanolamine N-methyltransferase Phosphoethanolamine/phosphocholine phosphatase 1 Phospholipase ABHD3 StAR related lipid transfer domain containing 10 StAR related lipid transfer domain containing 7 choline-phosphate cytidylyltransferase choline-phosphate cytidylyltransferase ethanolamine kinase ethanolamine kinase phosphatidate phosphatase phosphatidate phosphatase phosphatidate phosphatase	A0A3Q1LKP8 A0A3Q1LRY5 A0A3Q1LV95 A0A3Q1LZP9 A0A3Q1MPV1 A0A3Q1MRL1 A0A3Q1N9G5 A3KMY4 A5D7H3 A5PK40 A6QQA1 E1BCN8 E1BIP2 E1BLQ9 F1MJ55 F1MLQ5 F1MTK4 F1N4Z8 F1N5M4 P02720 P67868 P68399 Q0VC00 Q1LZE6 Q2KIR5 Q7YRH6	ABHD3 CEPT1 CHAT CHKA CHKB CHPT1 CK2A1 CK2N CPT1 CSNK2A1 CSNK2A2 CSNK2B CTL2 CTL3 CTL4 LPCAT1 LPIN1 LPIN2 LPIN3 MFSD2 MFSD2A PCTP PCYT1A PCYT1B PEMT PEMT2 PHOSPHO1 SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC44A5 STARD10 STARD2 STARD7 TPPT1	Bos taurus (cattle)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	AKR1C4 protein Carbonyl reductase [NADPH] 1 Dihydrodiol dehydrogenase 3 NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein NADP-dependent oxidoreductase domain-containing protein Prostacyclin synthase Prostaglandin E synthase 2 Prostaglandin E synthase 3 Prostaglandin E synthase Prostaglandin F synthase 2 Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2 Prostaglandin-H2 D-isomerase Thromboxane-A synthase glutathione transferase	A0A3Q1LFK5 A0A3Q1LIA5 A0A452DI94 A0A452DIU3 E1BG58 E1BP71 F1MGZ9 F1MNC0 F1MNI5 F1MT58 M0QW04 M0QW14 M0QW25 O02853 P52897 P52898 Q29626 Q3SZD7 Q3ZBG2 Q95L14	AKR1C4 CBR1 CYP8 HPGDS LOC506594 LOC538060 LOC782061 LOC782884 LOC785762 PTGDS PTGES PTGES2 PTGES3 PTGIS PTGS1 PTGS2 TBXAS1	Bos taurus (cattle)
Synthesis of glycosylphosphatidylinositol (GPI)	Dolichol phosphate-mannose biosynthesis regulatory protein GPI ethanolamine phosphate transferase 1 GPI ethanolamine phosphate transferase 2 GPI mannosyltransferase 2 GPI mannosyltransferase 3 Mannosyltransferase N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase Phosphatidylinositol N-acetylglucosaminyltransferase subunit C Phosphatidylinositol N-acetylglucosaminyltransferase subunit P Phosphatidylinositol glycan anchor biosynthesis class F Phosphatidylinositol glycan anchor biosynthesis class H Phosphatidylinositol-glycan biosynthesis class W protein phosphatidylinositol N-acetylglucosaminyltransferase	A0A3Q1LZ81 A6QQ24 E1B9Z8 E1BCR7 E1BM45 F1MGP1 F1MNK5 F1MYZ5 F1N3J6 Q1LZA0 Q32PC8 Q3ZBX1 Q58D07	DPM2 GPI7 PIGA PIGB PIGC PIGF PIGG PIGH PIGL PIGN PIGP PIGV PIGW PIGZ	Bos taurus (cattle)
Synthesis of very long-chain fatty acyl-CoAs	17beta-estradiol 17-dehydrogenase Elongation of very long chain fatty acids protein 2 Elongation of very long chain fatty acids protein 3 Elongation of very long chain fatty acids protein 6 Long-chain-fatty-acid--CoA ligase Long-chain-fatty-acid--CoA ligase Long-chain-fatty-acid--CoA ligase Malonate--CoA ligase ACSF3, mitochondrial Trans-2,3-enoyl-CoA reductase-like Very long chain fatty acid elongase 5 Very long chain fatty acid elongase 7 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase Very-long-chain 3-oxoacyl-CoA reductase Very-long-chain enoyl-CoA reductase long-chain-fatty-acid--CoA ligase long-chain-fatty-acid--CoA ligase	A0A3Q1LPX2 A0A3Q1LWT4 A0JNC4 A4FUF2 A6H7H3 A6QNQ7 A7YY55 E1BBR7 F1MBW3 F1MEX9 F1MXJ1 F1MXT1 F1N0H2 F6RUH3 Q1LZF6 Q2KJD9 Q3SZ89 Q3ZCD7 Q58DN7	ACSF3 ACSL1 ACSL3 ACSL4 ACSL5 ACSL6 ELOVL2 ELOVL3 ELOVL5 ELOVL6 ELOVL7 GPSN2 HACD1 HACD2 HACD3 HACD4 HSD17B12 HSD17B3 LOC789567 MGC139109 PTPLAD1 SRD5A2L2 TECR TECRL	Bos taurus (cattle)
Synthesis, secretion, and deacylation of Ghrelin	Appetite-regulating hormone Cholinesterase Growth hormone 1 Insulin-like growth factor I Insulin Leptin Membrane bound O-acyltransferase domain containing 4 Neuroendocrine convertase 1 Platelet-activating factor acetylhydrolase Pro-glucagon Signal peptidase complex catalytic subunit SEC11 Signal peptidase complex catalytic subunit SEC11A Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3	A0A3Q1LZG1 A0A3Q1MLX7 A5PJB2 E1BAE4 E1BEI2 F1MFR6 G8BLB4 P01272 P07455 P32749 P67810 Q1RML9 Q2KI36 Q3SZU5 Q9BDJ6	BCHE GCG GH1 GHRL IGF1 INS LEP MBOAT4 PCSK1 PLA2G7 SEC11A SEC11C SEC11L1 SPC18 SPCS1 SPCS2 SPCS3 ob	Bos taurus (cattle)	G58161NS
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl peptidase 4 Free fatty acid receptor 4 G protein subunit beta 3 G protein subunit gamma 13 G protein-coupled receptor 119 Gastrin-releasing peptide Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(t) subunit alpha-3 Leptin Pro-glucagon	A0A3Q1NGS8 E1B8Q3 E1BKC0 G5E5H9 G8BLB4 P01272 P0C7Q4 P62871 P81425 Q863C3	CD26 DPP4 FFAR4 GCG GNAT3 GNB1 GNB3 GNG13 GPR119 GPR120 GRP LEP ob	Bos taurus (cattle)	G58161NS
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	Dipeptidyl peptidase 4 G protein-coupled receptor 119 Gastric inhibitory polypeptide	F1MQC0 G5E5H9 P81425	CD26 DPP4 GIP GPR119	Bos taurus (cattle)
TAK1-dependent IKK and NF-kappa-B activation	Advanced glycosylation end-product specific receptor Amyloid-beta A4 protein High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) NF-kappa-B inhibitor-interacting Ras-like protein 2 NF-kappaB transcription factor p65 subunit NFKB inhibitor interacting Ras like 1 NFKB2 protein Nuclear factor NF-kappa-B p105 subunit Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta Protein S100-A12 Protein S100-B	A0A3Q1LUG2 A0A3Q1LZM4 A1XG22 A7MBB7 F1MKW9 F1N306 P02638 P10103 P79105 Q0IIB2 Q1JPF1 Q8WNW7 Q95KU9 Q95KV0 Q95KV1	AGER APP CAAF1 CHUK HMG1 HMGB1 IKBKB IKBKG IKKA NEMO NFKB1 NFKB2 NFKBIA NFKBIB NKIRAS1 NKIRAS2 RELA S100A12 S100B bIkBa	Bos taurus (cattle)
TCF dependent signaling in response to WNT	Axin 2 Axin-1 Catenin beta-1 E3 ubiquitin-protein ligase RNF146-B Poly [ADP-ribose] polymerase Poly [ADP-ribose] polymerase Polyubiquitin-B Polyubiquitin-C Protein Wnt Protein Wnt Protein Wnt Protein Wnt Ubiquitin specific peptidase 34 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1LTW2 A0A3Q1M230 A0A3Q1MDV7 E1B8R5 E1BDG5 E1BEN9 F1N5R1 G3X7P3 M5FK80 P0CG53 P0CH28 P62992 P63048 Q0VCX4 Q3T139	AXIN1 AXIN2 CTNNB1 RNF146B RPS27A TNKS TNKS2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP34 WNT1 WNT3 WNT3A WNT5A	Bos taurus (cattle)
TFAP2 (AP-2) family regulates transcription of cell cycle factors	Myc proto-oncogene protein Transcription factor AP-2 gamma [histone H3]-trimethyl-L-lysine(4) demethylase	F1MUR2 Q0VC14 Q2HJ27	KDM5B MYC TFAP2C	Bos taurus (cattle)
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	ATPase family AAA domain containing 2 Estrogen receptor Glycoprotein hormones alpha chain Lutropin subunit beta	E1BC78 P01217 P04651 P49884	ATAD2 CGA ESR ESR1 LHB NR3A1	Bos taurus (cattle)
TGF-beta receptor signaling activates SMADs	E3 ubiquitin-protein ligase CBL Integrin beta-6 Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha V Latent transforming growth factor beta binding protein 1 Latent transforming growth factor beta binding protein 2 Latent transforming growth factor beta binding protein 3 Latent transforming growth factor beta binding protein 4 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog NEDD8-conjugating enzyme Ubc12 NEDD8 Peptidyl-prolyl cis-trans isomerase FKBP1A Serine/threonine-protein kinase receptor TGF-beta receptor type-1 Transforming growth factor beta receptor 3 Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta Zinc finger FYVE domain-containing protein furin	A0A140T8D2 A0A3Q1LJU9 A0A3Q1LN00 A0A3Q1MXS2 A0A3Q1N449 A3KN22 A6QP91 B0JYL0 B0JYR0 E1B9H5 E1BE92 F1MF86 F1MKY4 F1MTN1 F1MUZ3 F1MVW3 F1N444 G3MZT8 G3MZV8 O46680 P18203 P21214 P61282 Q8SQB8 Q8SQB9	CBL FKBP1 FKBP1A FURIN ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 LTBP1 LTBP2 LTBP3 LTBP4 NEDD8 SMAD2 SMAD3 SMAD4 TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TGFBR3 UBC12 UBE2M ZFYVE9	Bos taurus (cattle)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	Cingulin E3 ubiquitin-protein ligase Junctional adhesion molecule A Par-3 family cell polarity regulator Par-6 family cell polarity regulator alpha Polyubiquitin-B Polyubiquitin-C Protein kinase C Rho/Rac guanine nucleotide exchange factor 18 Serine/threonine-protein kinase receptor TGF-beta receptor type-1 Transforming growth factor beta-1 proprotein Transforming protein RhoA Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1M590 A0A3Q1MSP9 A0A3Q1N449 E1B9G8 F1MLS5 F1MYN2 F6RHP0 G3MZV8 O46680 P0CG53 P0CH28 P61585 P62992 P63048 Q9XT56	ARHA ARHGEF18 CGN F11R JAM1 PARD3 PARD6A PRKCZ RHO12 RHOA RPS27A SMURF1 TGFB1 TGFBR1 TGFBR2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Bos taurus (cattle)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	B-cell activating factor Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing 3 CD40 ligand CD40 ligand LTBR protein Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 TNF receptor superfamily member 11a TNF receptor superfamily member 12A TNF receptor superfamily member 13C TNF receptor-associated factor TNF receptor-associated factor TNF superfamily member 12 TNF superfamily member 14 Tumor necrosis factor ligand superfamily member Tumor necrosis factor receptor superfamily member 5	A0A3Q1LHY0 A0A3Q1MKD6 A0A452DIT3 A6QQ46 B0LKN7 E1B9D9 E1BBH2 E1BIP0 E1BK50 E1BL08 F1MJD0 F1MTC1 F1MX43 F1N0K4 G3X822 Q06600 Q28203 Q3SYW8	BIRC2 BIRC3 CD40 CD40LG LTA LTB LTBR MAP3K14 NCR3 TNFB TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF5 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNLG1D TNLG7A TRAF2 TRAF3	Bos taurus (cattle)
TNFR2 non-canonical NF-kB pathway	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 B-cell activating factor Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing 3 CD40 ligand CD40 ligand LTBR protein Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta TNF receptor superfamily member 11a TNF receptor superfamily member 12A TNF receptor superfamily member 13C TNF receptor superfamily member 1B TNF receptor-associated factor TNF receptor-associated factor TNF superfamily member 12 TNF superfamily member 14 Tumor necrosis factor ligand superfamily member Tumor necrosis factor receptor superfamily member 5 Tumor necrosis factor	A0A3Q1LHY0 A0A3Q1MKD6 A0A452DI44 A0A452DIT3 A0A452DIY4 A0A452DJ61 A6QQ46 A7MBA2 B0LKN7 E1B9D9 E1BBH2 E1BD83 E1BIP0 E1BK50 E1BL08 F1MBI1 F1MJD0 F1MLV1 F1MTC1 F1MWE0 F1MX43 F1MXE4 F1MYH8 F1N0K4 F1N6Z0 G3X822 G5E589 P33672 P56701 P62194 Q06600 Q17QP9 Q28203 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHI9 Q3MHN0 Q3SX30 Q3SYW8 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	BIRC2 BIRC3 CD40 CD40LG LTA LTB LTBR MAP3K14 NCR3 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 SUG1 TNF TNFB TNFRSF11A TNFRSF12A TNFRSF13C TNFRSF1B TNFRSF5 TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNLG1D TNLG7A TRAF2 TRAF3 TRAP2	Bos taurus (cattle)
TNFs bind their physiological receptors	A proliferation-inducing ligand B-cell activating factor CD27 molecule CD70 molecule EDAR associated death domain Ectodysplasin A receptor Ectodysplasin A Lymphotoxin-alpha TNF receptor superfamily member 13B TNF receptor superfamily member 17 TNF receptor superfamily member 1B TNF receptor superfamily member 25 TNF receptor superfamily member 4 TNF receptor superfamily member 8 TNF receptor superfamily member 9 TNF superfamily member 14 TNF superfamily member 15 TNF superfamily member 4 TNF superfamily member 8 TNF superfamily member 9 TNFRSF6B protein Tumor necrosis factor ligand superfamily member Tumor necrosis factor receptor superfamily member 11B Tumor necrosis factor receptor superfamily member 1A Uncharacterized protein LOC768081	A0A3Q1LIC4 A0A3Q1M5M3 A0A3Q1M673 A0A3Q1MQ33 A0A452DII6 A5D7R1 A6QPW7 B0LKN7 E1B972 E1BBS7 E1BF06 E1BGY4 E1BIP0 E1BPZ2 F1MGQ7 F1MU29 F1MXW8 F1N0K4 F1N0U5 F1N4E2 G3MZW3 Q06600 Q08DT5 Q3MHI9 Q3ZBM0	APRIL CD27 CD70 EDA EDAR EDARADD LOC768081 LTA TNFB TNFRSF11B TNFRSF13B TNFRSF17 TNFRSF1A TNFRSF1B TNFRSF25 TNFRSF4 TNFRSF6B TNFRSF8 TNFRSF9 TNFSF1 TNFSF11 TNFSF13 TNFSF13B TNFSF14 TNFSF15 TNFSF18 TNFSF4 TNFSF8 TNFSF9 TNLG1B TNLG1D TNLG7A TNLG8A	Bos taurus (cattle)
TP53 Regulates Metabolic Genes	14-3-3 protein beta/alpha 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma 14-3-3 protein sigma 14-3-3 protein theta 14-3-3 protein zeta/delta 5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-3 Acetyl-CoA carboxylase kinase Cytochrome c oxidase assembly factor COX18 Cytochrome c oxidase assembly protein COX11, mitochondrial Cytochrome c oxidase assembly protein COX14 Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 3 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 6A1, mitochondrial Cytochrome c oxidase subunit 6C Cytochrome c oxidase subunit 7A-related protein, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit 8 Cytochrome c oxidase subunit NDUFA4 Cytochrome c oxidase subunit NDUFA4 Cytochrome c DNA damage-inducible transcript 4 protein Fructose-2,6-bisphosphatase TIGAR Glucose-6-phosphate 1-dehydrogenase Glucose-6-phosphate isomerase Glutathione reductase Leucine rich pentatricopeptide repeat containing Neutral amino acid transporter 9 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-5, mitochondrial Protein SCO1 homolog, mitochondrial Protein SCO2 homolog, mitochondrial Protein kinase AMP-activated non-catalytic subunit beta 2 Protein kinase AMP-activated non-catalytic subunit gamma 2 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras homolog, mTORC1 binding Ras-related GTP-binding protein A Ras-related GTP-binding protein Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory associated protein of MTOR complex 1 SESN1 protein SURF1-like protein Serine/threonine-protein kinase mTOR Sestrin 3 Sestrin-2 TSC complex subunit 1 Target of rapamycin complex subunit LST8 Thioredoxin reductase 1, cytoplasmic Thioredoxin Translational activator of cytochrome c oxidase I Uncharacterized protein glutaminase glutaminase	A0A0N4STN2 A0A140T894 A0A3Q1LKB8 A0A3Q1LTU9 A0A3Q1LYC8 A0A3Q1M6L2 A0A3Q1MM55 A0A3Q1MMW4 A0A3Q1MQS6 A0A3Q1MSS5 A0A3Q1MVT8 A1A4J8 A3KMZ6 A6H784 A7MBI2 A7Z057 A8E4L1 E1B986 E1BFB4 E1BH77 E1BHZ6 E1BJK7 E1BKZ1 E1BPX9 F1MBG5 F1MFJ7 F1MG06 F1MM79 F1MM99 F1MQV7 F1N5P2 F2Z4I1 G5E5G3 O62768 O97680 P00423 P00426 P00430 P04038 P13182 P58108 P62261 P62894 P63103 P68509 P68530 Q01321 Q08E62 Q0VC36 Q0VD29 Q17QQ1 Q17QU5 Q1JQA7 Q1RMH3 Q2LL38 Q2M2U3 Q2NKS2 Q3SX43 Q3SZ68 Q3SZI4 Q3T061 Q3T0D8 Q3T132 Q3ZBD7 Q58CN8 Q5BIS9 Q5E947 Q6QTG5 Q6QTG9 Q9BGI1 Q9BGI3	COII COX1 COX11 COX14 COX16 COX18 COX19 COX2 COX20 COX3 COX4 COX4I1 COX5A COX6A1 COX6C COX7A2L COX7B COX7C COX7CP1 COXII CYC CYCS DDIT4 G6PD GBL GLS GLS2 GPI GSR LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LOC100296227 LOC783202 LRPPRC LST8 MLST8 MT-CO2 MTCO2 MTOR NDUFA4 PRDX1 PRDX2 PRDX5 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RHEB RPTOR RRAGA RRAGB RRAGC RRAGD SCO1 SCO2 SCOD1 SESN1 SESN2 SESN3 SFN SLC38A9 SURF1 TACO1 TIGAR TSC1 TXN TXNRD1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	Bos taurus (cattle)

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