GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **501 - 525** of **557** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID ▲
Transport of inorganic cations/anions and amino acids/oligopeptides	Amino acid transporter Amino acid transporter Amino acid transporter Amino acid transporter Cystinosin Excitatory amino acid transporter 1 Mitochondrial S-adenosylmethionine carrier protein Vesicular inhibitory amino acid transporter	A0A3Q1MR13 A6H774 A6QR09 A7MB63 F1MJN4 F1MUT8 G3N354 P46411	CTNS EAAT1 GLAST GLAST1 SAMC SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 SLC25A26 SLC32A1	Bos taurus (cattle)
Transport of vitamins, nucleosides, and related molecules	PDZ domain-containing protein 11 Solute carrier family 33 (Acetyl-CoA transporter), member 1 Solute carrier family 5 member 6	F1MN65 Q0VCP0 Q32LE7	PDZD11 SLC33A1 SLC5A6	Bos taurus (cattle)
Heme degradation	ABC-type glutathione-S-conjugate transporter Albumin Biliverdin reductase A Broad substrate specificity ATP-binding cassette transporter ABCG2 Fatty acid-binding protein, liver Flavin reductase (NADPH) Glutathione S-transferase A2 Glutathione S-transferase Glutathione S-transferase Glutathione S-transferase Heme oxygenase 1 Multidrug resistance-associated protein 1 Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member UDP-glucuronosyltransferase heme oxygenase (biliverdin-producing)	A0A140T897 A0A3Q1M423 A0A3Q1MEC8 A0A3Q1MQ83 A0A3S5ZP51 B2D1N9 E1BKD8 F1MIP7 F1MTY9 F1MX44 F1MYV0 O18879 P52556 P80425 Q5E9F2 Q8HXQ5	ABCC1 ABCC2 ABCG2 ALB BLVRA BLVRB FABP1 GSTA1 GSTA2 GSTA5 HMOX1 HMOX2 MRP1 SCAN SLCO1B3 SLCO2B1 UGT1A6	Bos taurus (cattle)
Terminal pathway of complement	Clusterin Complement C5 Complement C7 Complement C8 alpha chain Complement component C8 beta chain Complement component C9	A0A3Q1LI40 F1MX87 F1MY85 F1N102 P17697 Q3MHN2	C5 C7 C8A C8B C9 CLU	Bos taurus (cattle)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	Potassium channel subfamily K member 1 Potassium channel subfamily K member	E1B9M4 Q0P5A0	KCNK1 KCNK7	Bos taurus (cattle)
Degradation of the extracellular matrix	72 kDa type IV collagenase A disintegrin and metalloproteinase with thrombospondin motifs 4 ADAM metallopeptidase domain 15 ADAM metallopeptidase with thrombospondin type 1 motif 5 Aggrecan core protein Basigin Brevican core protein CD44 antigen Cadherin-1 Calpain 10 Calpain 12 Calpain 13 Calpain 14 Calpain 5 Calpain 6 Calpain 7 Calpain 8 Calpain small subunit 1 Calpain-1 catalytic subunit Calpain-2 catalytic subunit Calpain-3 Calpastatin Cathepsin K Cathepsin S Collagenase 3 Decorin Disintegrin and metalloproteinase domain-containing protein 10 Elastase, neutrophil expressed HtrA serine peptidase 1 Kallikrein-related peptidase 7 Matrix metallopeptidase 12 Matrix metallopeptidase 19 Matrix metallopeptidase 7 Matrix metallopeptidase 8 Matrix metalloproteinase-14 Matrix metalloproteinase-9 NID1 protein Opticin Peptidase S1 domain-containing protein Procathepsin L Secreted phosphoprotein 1 Signal peptide, CUB domain and EGF like domain containing 1 Signal peptide, CUB domain and EGF like domain containing 3 Stromelysin-1 Transmembrane serine protease 6 interstitial collagenase	A0A3Q1LJS3 A0A3Q1LZU0 A0A3Q1M4A6 A0A3Q1MG91 A0A3Q1MSS6 A0A3Q1MZC5 A0A452DI93 A0A452DJ01 A6QNS6 A6QP82 E1BAD2 E1BI66 E1BIX3 E1BJ18 E1BKJ3 F1MB09 F1MBN8 F1MJF1 F1MKH8 F1MQ31 F1MQD1 F1MQT9 F1MRZ2 F1MT97 F1MTX6 F1MU56 F1MW26 F1MWW8 F1N121 F1N1E3 F1N368 F6RFP6 G3MWP1 G3N0J0 G8JKX1 P13135 P21793 P25326 P25975 P52176 P58874 Q08D90 Q08DI9 Q10741 Q27971 Q5E968	ACAN ADAM10 ADAM15 ADAMTS4 ADAMTS5 BCAN BSG CAPN1 CAPN10 CAPN12 CAPN13 CAPN14 CAPN2 CAPN3 CAPN4 CAPN5 CAPN6 CAPN7 CAPN8 CAPNS1 CAST CD44 CDH1 CTSK CTSL CTSL1 CTSS DCN ELANE HTRA1 KLK7 LOC112441463 LOC509956 MADM MMP12 MMP13 MMP14 MMP19 MMP2 MMP3 MMP7 MMP8 MMP9 NID1 OPT OPTC SCUBE1 SCUBE3 SPP1 TMPRSS6	Bos taurus (cattle)
P2Y receptors	G protein-coupled receptor 17 LPAR4 protein Lysophosphatidic acid receptor 6 P2Y purinoceptor 14 P2Y purinoceptor 1 P2Y purinoceptor 2 P2Y purinoceptor 4 P2Y receptor family member 10 Purinergic receptor P2Y, G-protein coupled, 12 Purinergic receptor P2Y11 Pyrimidinergic receptor P2Y6	A2VEA2 A4IFV1 A6QL49 F1MDI7 F1MDW9 F1MTB2 F1MU50 G3X6Q0 P48042 Q0IIL0 Q3SX17	GPR17 LPAR4 LPAR6 P2RY1 P2RY10 P2RY11 P2RY12 P2RY14 P2RY2 P2RY4 P2RY5 P2RY6	Bos taurus (cattle)
NTF3 activates NTRK3 signaling	Neurotrophin-3 Tyrosine-protein kinase receptor	G3N3T6 Q08DT3	NTF3 NTRK3	Bos taurus (cattle)
Stimuli-sensing channels	Acid sensing ion channel subunit 1 Acid sensing ion channel subunit family member 4 Acid sensing ion channel subunit family member 5 Amiloride-sensitive cation channel 1, neuronal Amiloride-sensitive sodium channel subunit alpha Amiloride-sensitive sodium channel subunit beta Amiloride-sensitive sodium channel subunit gamma Anoctamin-4 Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Aspartyl/asparaginyl beta-hydroxylase Bestrophin-2 Bestrophin Bestrophin Bestrophin Calcium-activated chloride channel regulator 1 Calmodulin-like Chloride channel accessory 4 Chloride channel protein 2 Chloride channel protein Chloride channel protein Chloride channel protein Chloride intracellular channel 2 Chloride voltage-gated channel 1 EF-hand domain-containing protein H(+)/Cl(-) exchange transporter 7 Osteoclastosis associated transmembrane protein 1 Peptidyl-prolyl cis-trans isomerase FKBP1B Protein tweety homolog Protein tweety homolog Protein tweety homolog Ryanodine receptor 2 STOM protein Sodium channel epithelial 1 subunit delta Sodium leak channel, non-selective Solute carrier family 17 (Sodium phosphate), member 3 Solute carrier family 9 member B2 Solute carrier family 9, subfamily B (cation proton antiporter 2), member 1 Sorcin Stomatin like 3 Two pore segment channel 1 Two pore segment channel 2 Unc-79 homolog, NALCN channel complex subunit Unc-80 homolog, NALCN channel complex subunit Uncharacterized protein	A0A3Q1LL71 A0A3Q1LNC2 A0A3Q1LUZ5 A0A3Q1M2M7 A0A3Q1M2Y5 A0A3Q1MHC3 A0A3Q1MQ38 A0A3Q1MR28 A0A3Q1MUE0 A0A3Q1N2G9 A1A4I7 A2VE46 A5D7U4 A6QLE6 A6QNR5 A7YWH0 A8E4P3 E1B792 E1BF86 E1BF90 E1BFC4 E1BFF1 E1BHV1 E1BJF8 E1BK15 E1BLQ0 E1BMN1 F1MCB3 F1MFR7 F1MGK7 F1MGZ5 F1MJ95 F1MJW3 F1MLH6 F1MN45 F1MPC2 F1MTH0 F1MX70 F1MY57 F1N0S4 F6QQY9 G3N0G4 G3N3A9 P55270 P68107 Q0VC38 Q17QE9 Q28056 Q3SYU0 Q4PKH3	ACCN1 ANO10 ANO2 ANO3 ANO4 ANO5 ANO6 ANO8 ANO9 ASIC1 ASIC2 ASIC4 ASIC5 ASPH BEST1 BEST2 BEST3 BEST4 CALM CLCA1 CLCA4 CLCN1 CLCN2 CLCN3 CLCN5 CLCN6 CLCN7 CLCNKA CLIC2 FKBP12.6 FKBP1B NALCN NHEDC1 OSTM1 RYR2 SCNN1A SCNN1B SCNN1D SCNN1G SLC17A3 SLC9B2 SRI STOM STOML3 TMEM16D TPCN1 TPCN2 TTYH1 TTYH2 TTYH3 UNC79 UNC80	Bos taurus (cattle)
Nuclear events mediated by NFE2L2	5'-AMP-activated protein kinase catalytic subunit alpha-2 NFE2 like bZIP transcription factor 2 histone acetyltransferase histone acetyltransferase	A0A3Q1LRK0 E1B8D6 F1MD32 F1MQV7	CREBBP EP300 NFE2L2 PRKAA2	Bos taurus (cattle)
RHOA GTPase cycle	A-kinase anchoring protein 13 ABCD3 protein Actin, alpha cardiac muscle 1 Active breakpoint cluster region-related protein Acyl-CoA-binding domain-containing protein 5 Aladin WD repeat nucleoporin Anillin, actin binding protein ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 B-cell receptor-associated protein BCR activator of RhoGEF and GTPase Caveolae associated protein 1 Caveolin-1 Coiled-coil domain-containing protein 115 Complement component 1 Q subcomponent-binding protein, mitochondrial DDRGK domain-containing protein 1 DEP domain containing 1B Dedicator of cytokinesis 2 Delta(14)-sterol reductase LBR Diaphanous related formin 1 Diaphanous related formin 3 Dishevelled associated activator of morphosis 1 ER membrane protein complex subunit 3 Endoplasmic reticulum protein 27 FAS-associated factor 2 FERM, ARHGEF and pleckstrin domain-containing protein 1 Family with sequence similarity 13 member A Flotillin-1 Flotillin-2 Formin like 3 GMIP protein IQ motif containing GTPase activating protein 1 IQGAP3 protein Junction plakoglobin Kinectin 1 Lectin, mannose binding 1 MCF.2 cell line derived transforming sequence like MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule Myosin IXB Neuroepithelial cell transforming 1 Neuronal guanine nucleotide exchange factor Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 Phospholipase Pleckstrin homology and RhoGEF domain containing G3 Pleckstrin homology and RhoGEF domain containing G5 Pleckstrin homology and RhoGEF domain containing G6 Progesterone receptor membrane component 2 Proto-oncogene vav Protocadherin 7 Rac GTPase activating protein 1 Ras protein specific guanine nucleotide releasing factor 2 Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 18 Rho GTPase activating protein 19 Rho GTPase activating protein 1 Rho GTPase activating protein 20 Rho GTPase activating protein 22 Rho GTPase activating protein 23 Rho GTPase activating protein 24 Rho GTPase activating protein 28 Rho GTPase activating protein 30 Rho GTPase activating protein 31 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 42 Rho GTPase activating protein 44 Rho GTPase activating protein 45 Rho GTPase activating protein 4 Rho GTPase activating protein 5 Rho GTPase activating protein 6 Rho GTPase activating protein 8 Rho GTPase activating protein 9 Rho GTPase-activating protein 10 Rho GTPase-activating protein 26 Rho GTPase-activating protein 29 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 7 Rho-GAP domain-containing protein Rho-associated protein kinase Rho/Rac guanine nucleotide exchange factor 18 Rhophilin-2 Rhotekin SLIT-ROBO Rho GTPase activating protein 1 STOM protein Sec1 family domain containing 1 Serine/threonine-protein kinase N1 StAR related lipid transfer domain containing 13 StAR related lipid transfer domain containing 8 Starch binding domain 1 Synaptobrevin homolog YKT6 Synaptosomal-associated protein Syntaxin-5 T-cell activation GTPase activating protein TMEM87A protein Testis expressed 2 Tight junction protein 2 Transferrin receptor protein 1 Transforming protein RhoA V-type proton ATPase subunit S1 Vang-like protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Vesicle-associated membrane protein-associated protein B heme oxygenase (biliverdin-producing) non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase protein kinase C protein kinase C	A0A3Q1LFQ5 A0A3Q1LGT5 A0A3Q1LHF1 A0A3Q1LKT3 A0A3Q1LM61 A0A3Q1LNB6 A0A3Q1LNE2 A0A3Q1LQ45 A0A3Q1LUD9 A0A3Q1LUW4 A0A3Q1LVS2 A0A3Q1LWV5 A0A3Q1LWX5 A0A3Q1LX25 A0A3Q1M2Q1 A0A3Q1M4A0 A0A3Q1M4M7 A0A3Q1M851 A0A3Q1M8D9 A0A3Q1MA88 A0A3Q1MAP3 A0A3Q1MD11 A0A3Q1MEH9 A0A3Q1MFP5 A0A3Q1MN47 A0A3Q1MPX1 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MSA1 A0A3Q1MT43 A0A3Q1MW77 A0A3Q1N5A2 A0A3Q1N6F4 A0A3Q1N6J8 A0A452DIS6 A0A452DJ82 A1A4I4 A2VDZ9 A4FUC9 A4FV18 A4FV22 A6H7H0 A6QLR4 A6QNS3 A6QQV8 A7YY57 A7Z038 A8E4P3 E1B718 E1B801 E1B9G8 E1BAJ4 E1BBA0 E1BBD2 E1BCC1 E1BCK4 E1BDL7 E1BDY4 E1BG76 E1BH05 E1BH51 E1BHQ9 E1BI70 E1BIG6 E1BIM3 E1BJP2 E1BLB3 E1BM23 E1BMN2 E1BNE7 E1BNR7 E1BNV7 E1BP14 E1BQ24 F1MBM9 F1MBT6 F1MC48 F1MCL8 F1MCN4 F1MEK6 F1MF50 F1MFA5 F1MFC6 F1MFK1 F1MFS4 F1MGB9 F1MHI2 F1MIZ6 F1MJA6 F1MJH8 F1MK36 F1MLS2 F1MM72 F1MPJ6 F1MS34 F1MTN6 F1MTY9 F1MWY5 F1MYQ4 F1N1Q7 F1N2G5 F1N6V1 F1N7Q8 F6QCG0 F6QJJ8 F6RWK1 G3N2T3 G3X696 G5E6T2 P23726 P23727 P40682 P61585 P79132 Q08DA6 Q08DB1 Q08DB5 Q08DN7 Q08DN8 Q08DP6 Q2HJD0 Q2T9M8 Q3SZB5 Q3T000 Q3T0B6 Q3ZC07 Q3ZCB8 Q5E9F1 Q8SPJ1	AAAS ABCD3 ABR ACBD5 ACTC ACTC1 AKAP13 ANLN ARAP1 ARAP2 ARAP3 ARHA ARHGAP1 ARHGAP10 ARHGAP11A ARHGAP18 ARHGAP19 ARHGAP20 ARHGAP22 ARHGAP23 ARHGAP24 ARHGAP26 ARHGAP28 ARHGAP29 ARHGAP30 ARHGAP31 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP4 ARHGAP42 ARHGAP44 ARHGAP45 ARHGAP5 ARHGAP6 ARHGAP8 ARHGAP9 ARHGDIA ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF25 ARHGEF28 ARHGEF3 ARHGEF5 ARHGEF7 ATP6AP1 ATP6IP1 ATP6S1 BCAP31 BCR C1QBP CAV1 CAVIN1 CCDC115 DAAM1 DDRGK1 DEPDC1B DIAPH1 DIAPH3 DLC1 DOCK2 EMC3 ERP27 FAF2 FAM13A FARP1 FLOT1 FLOT2 FMNL3 GMIP HMOX2 IQGAP1 IQGAP3 JUP KTN1 LBR LMAN1 MCAM MCF2L MYO9B NET1 NGEF OPHN1 PCDH7 PGRMC2 PIK3R1 PIK3R2 PKN PKN1 PKN2 PKN3 PLD1 PLEKHG3 PLEKHG5 PLEKHG6 PREX1 PREX2 PRK1 PRKCL1 RACGAP1 RASGRF2 RHO12 RHOA RHPN2 ROCK1 ROCK2 RTKN SCFD1 SLK SNAP23 SRGAP1 STARD13 STARD8 STBD1 STOM STX5 TAGAP TEX2 TFRC TJP2 TMEM111 TMEM87A TRIO UBXD8 VANGL1 VAPB VAV1 VAV2 VAV3 YKT6	Bos taurus (cattle)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	ABC-type antigen peptide transporter Aminopeptidase Beta-2-microglobulin Calnexin Calreticulin Endoplasmic reticulum aminopeptidase 2 Endoplasmic reticulum chaperone BiP Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Protein SEC13 homolog Protein disulfide-isomerase Protein transport protein SEC23 Protein transport protein Sec24A Protein transport protein Sec31A SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Small COPII coat GTPase SAR1B Tapasin Transporter 1, ATP binding cassette subfamily B member	A0A3Q1LRW6 A0A3Q1MD45 A5D7E8 A5D7J6 A6QNT8 A6QPT7 A7Z066 E1BI37 E1BIU0 E1BJS0 E1BMP2 E1BPR4 F1MU34 F1MV07 F1MVW5 F1MVY8 F1MZQ5 F1N4Y5 P01888 Q0VCX2 Q2NL04 Q3T0T7 Q3ZCC9	B2M BOLA BOLA-NC1 CALR CANX ERAP1 ERAP2 GRP78 HSPA5 PDIA3 SAR1B SEC13 SEC13L1 SEC23A SEC24A SEC24B SEC24C SEC24D SEC31A TAP1 TAP2 TAPBP canx	Bos taurus (cattle)
PI3K Cascade	FLT3LG protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2 associated binding protein 2 GRB2-associated-binding protein 1 Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Klotho beta Klotho Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Toll-like receptor 9 Tyrosine-protein phosphatase non-receptor type non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A3Q1LQK4 A0A3Q1LRU7 A0A3Q1LUE0 A0A3Q1M3Q3 A0A3Q1M864 A0A3Q1MPT9 A0A3Q1NAV6 A0MTF4 A2VE24 A5H631 A6QLU3 A6QLW1 D8KXU9 E1B7I9 E1BAI2 E1BFP8 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MHC6 F1MJE0 F1MN51 F1MRU0 F1MYE0 F1MYM3 F1N339 F1N4S9 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969 P23726 P23727 P32871 Q3T0F9	AFGF FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF8A FGF9 FGFA FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 Fgf4 GAB1 GAB2 GRB2 HBGF-1 IRS1 IRS2 KL KLB PIK3C3 PIK3CA PIK3CB PIK3R1 PIK3R2 PIK3R4 PTPN11 TLR9	Bos taurus (cattle)
Integrin cell surface interactions	Basigin CD44 antigen Cadherin-1 Cartilage oligomeric matrix protein Collagen alpha-1(IV) chain Collagen type IV alpha 3 chain Collagen type XIII alpha 1 chain Collagen type XVI alpha 1 chain Collagen type XVIII alpha 1 chain Fibrillin-1 Fibronectin Integrin alpha-3 Integrin alpha-L Integrin beta-2 Integrin beta-6 Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 10 Integrin subunit alpha 11 Integrin subunit alpha 1 Integrin subunit alpha 2 Integrin subunit alpha 2b Integrin subunit alpha 4 Integrin subunit alpha 6 Integrin subunit alpha 9 Integrin subunit alpha M Integrin subunit alpha V Integrin-binding sialoprotein Intercellular adhesion molecule 1 Intercellular adhesion molecule 3 Intercellular adhesion molecule 5 Intercellular adhesion molecule N-terminal domain-containing protein JAM2 protein Junctional adhesion molecule A Leukocyte surface antigen CD47 Lumican Platelet and endothelial cell adhesion molecule 1 Purinergic receptor P2X 5 Secreted phosphoprotein 1 Tenascin C Thrombospondin 1 VCAM1 protein VWFA domain-containing protein Vitronectin	A0A140T8D2 A0A3Q1LT76 A0A3Q1LZT3 A0A3Q1LZU0 A0A3Q1M8K4 A0A3Q1MFX6 A0A3Q1MHJ9 A0A3Q1MQV3 A0A3Q1MSS6 A0A3Q1MXS2 A4IFI9 A7MBB0 E1BDD5 E1BFX5 E1BLR0 F1MBA3 F1MEF6 F1MGZ4 F1MI38 F1MMH2 F1MMN6 F1MMS9 F1MQF0 F1MQT9 F1MRZ6 F1MTN1 F1MVW3 F1MZU6 F1N157 F1N6W9 F6RFP6 F6RKH9 F6RND5 G3MXK9 G3MYD9 G5E5A9 P32592 P35445 P61625 P98133 Q05443 Q28862 Q3ZBS7 Q7SIB2 Q8SQB8 Q8SQB9 Q9XT56	BSG CD18 CD44 CD47 CDH1 COL13A1 COL16A1 COL18A1 COL4A1 COL4A3 COMP F11R FBN1 FN1 IBSP ICAM1 ICAM3 ICAM5 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA6 ITGA9 ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB5 ITGB6 ITGB7 ITGB8 JAM1 JAM2 LDC LOC534578 LOC616254 LUM P2RX5 PECAM1 SPP1 THBS1 TNC VCAM1 VTN	Bos taurus (cattle)
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor	A0A3Q1LRU7 A0A3Q1M3Q3 A0A3Q1NAV6 A0MTF4 D8KXU9 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MHC6 F1MYF9 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969	AFGF FGF1 FGF10 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF9 FGFA FGFR2 Fgf4 HBGF-1 PLCG1	Bos taurus (cattle)
Receptor-type tyrosine-protein phosphatases	Leucine rich repeat containing 4B PPFIA binding protein 1 PPFIA binding protein 2 PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 PTPRF interacting protein alpha 3 PTPRF interacting protein alpha 4 Receptor-type tyrosine-protein phosphatase F SLIT and NTRK like family member 1 SLIT and NTRK like family member 2 SLIT and NTRK like family member 3 SLIT and NTRK like family member 4 SLIT and NTRK like family member 5 SLIT and NTRK like family member 6 Tyrosine-protein kinase receptor Uncharacterized protein protein-tyrosine-phosphatase protein-tyrosine-phosphatase	A0A3Q1LQ22 A0A3Q1M422 A0A3Q1M5L6 A0A3Q1M5X2 A0A3Q1MBH3 A0A3Q1MZF8 A7MBJ4 E1B8X9 E1BFL8 E1BIA1 E1BPK8 F1MJJ9 F1MQQ8 F1MSM8 F1N513 F1N5L8 G3N2N1 G3N3T6	LOC101901895 LRRC4B NTRK3 PPFIA1 PPFIA2 PPFIA3 PPFIA4 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRS SLITRK1 SLITRK2 SLITRK3 SLITRK4 SLITRK5 SLITRK6	Bos taurus (cattle)
Translocation of ZAP-70 to Immunological synapse	BOLA-DQA1 protein BoLA-DR-alpha Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II antigen MHC class II antigen Major histocompatibility complex, class II, DQ alpha 5 Major histocompatibility complex, class II, DY alpha T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TRAV29-1*01 Tyrosine-protein kinase Tyrosine-protein kinase protein-tyrosine-phosphatase	A0A3Q1M088 A0A3Q1M3D2 A0A3Q1MT21 A6H6Y1 A6QQE7 E1BLZ1 E1BMP9 F1MJK4 F1MJU5 F1ML60 F1N0X9 F1N6L3 G3MWT2 G8JL01 Q0VCU4 Q28072 Q28073 Q30309 Q3ZCM0 Q70IB5	BLA-DQB BOLA-DQA1 BOLA-DQA2 BOLA-DQA5 BOLA-DRA BOLA-DRB2 BOLA-DRB3 BOLA-DYA BOLA-DYB BoLA-DIB BoLA-DRA BoLA-DYB CD247 CD3D CD3E CD3G CD4 DYB HLA-DRA LCK LOC100848815 PTPN22 TRAV29-1 ZAP70	Bos taurus (cattle)
Dermatan sulfate biosynthesis	Biglycan Brevican core protein Carbohydrate sulfotransferase Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 (Neuroglycan C) Decorin Dermatan sulfate epimerase like Dermatan sulfate epimerase Neurocan Uronyl 2-sulfotransferase Versican core protein	A0A3Q1M5X6 A3KMX1 F1ME12 F1MM96 F1MQ31 F1MY84 F1N2Y8 P21793 P21809 P81282 Q0VCM1	BCAN BGN CHST14 CSPG2 CSPG4 CSPG5 DCN DSE DSEL NCAN UST VCAN	Bos taurus (cattle)
SUMOylation of intracellular receptors	Androgen receptor Estrogen receptor Glucocorticoid receptor Histone deacetylase Mineralocorticoid receptor NR1I2 protein Nuclear receptor subfamily 1 group H member 4 Nuclear receptor subfamily 5 group A member 2 Oxysterols receptor LXR-alpha Oxysterols receptor LXR-beta PIAS3 protein PIAS4 protein Peroxisome proliferator-activated receptor alpha Progesterone receptor Protein inhibitor of activated STAT 1 Protein inhibitor of activated STAT 2 Rad60/SUMO-like domain-containing protein Rad60/SUMO-like domain-containing protein Retinoic acid receptor RXR Retinoic acid receptor alpha SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier 3 Steroidogenic factor 1 Thyroid hormone receptor alpha Thyroid hormone receptor beta Vitamin D3 receptor	A0A3Q1LPE8 A0A3Q1LUL4 A0A3Q1M2W5 A0A3Q1M5G9 A0A3Q1ML58 A0A3Q1N5N2 A0A3Q1N8R7 A2VDU4 A4FV15 A6QQU9 F1MN19 F1MTT1 F1MWQ3 F1MX52 F1MYR0 F1N2B6 F1N712 G3MZL6 G3X7C1 G5E5J5 P49884 P61955 Q04752 Q17QV3 Q5BIS6 Q5E9B6 Q5EA13	AD4BP AR ESR ESR1 FTZF1 HDAC4 LXRA LXRB NR1H2 NR1H3 NR1H4 NR1I2 NR3A1 NR3C1 NR3C2 NR5A1 NR5A2 PGR PIAS1 PIAS2 PIAS3 PIAS4 PPARA RARA RXRA SMT3B SUMO2 SUMO3 THRA THRB VDR	Bos taurus (cattle)
Physiological factors	Atrial natriuretic peptide receptor 2 C-type natriuretic peptide Carboxylic ester hydrolase Corin, serine peptidase Guanylate cyclase Natriuretic peptides A Neprilysin	A0A3Q1LLW8 A0A3Q1MQJ1 E1BN71 E1BPL8 P07501 P46197 P55206	CES1 CORIN MME NPPA NPPC NPR1 NPR2	Bos taurus (cattle)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Erythropoietin receptor Erythropoietin GRB2-associated-binding protein 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide 3-kinase regulatory subunit 5 Tyrosine-protein kinase Tyrosine-protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q1M2L5 A6QLU3 E1BCP6 E1BCV1 E1BE66 F1MEQ7 F1MJE0 F1MYM3 F1N261 P23727 P32871 P48617	EPO EPOR GAB1 IRS2 JAK2 LYN PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R5	Bos taurus (cattle)
Pyroptosis	Apoptosis regulator BAX BCL2-antagonist/killer 1 CHMP4B protein Caspase 1 Caspase-13 Caspase-3 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 7 Chromatin modifying protein 4C Chromatin modifying protein 6 Cytochrome c Elastase, neutrophil expressed Gasdermin D Gasdermin E Granzyme B High mobility group protein B1 Interleukin-1 alpha Interleukin-18 Multifunctional fusion protein	A0A140T838 A0A3Q1MD51 A0A3Q1MFA5 A2VDY3 A6H704 E1BFC3 F1MB04 F1MTF4 G3MWP1 O02703 O75601 P08831 P10103 P62894 Q05KI7 Q08E32 Q148L0 Q2HJ35 Q3SX42 Q3T0U5 Q58CS7 Q9TU73	BAK1 BAX CASP1 CASP13 CASP3 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 CYC CYCS ELANE GSDMD GSDME GZMB HMG1 HMGB1 IGIF IL18 IL1A IL1B VPS24	Bos taurus (cattle)
Lysosomal oligosaccharide catabolism	Alpha-mannosidase Beta-mannosidase Lysosomal alpha-mannosidase alpha-mannosidase	A0A3Q1MEZ5 A0A3S5ZPJ9 F1MWT0 Q29451	LOC528518 MAN2B1 MAN2C1 MANB MANBA	Bos taurus (cattle)	G00027MO G25577BM G28233ME G70323CJ G90333CG
HS-GAG degradation	Agrin Alpha-L-iduronidase Beta-galactosidase Beta-galactosidase Beta-glucuronidase Galactosidase beta 1 like Glypican 2 Glypican 4 Glypican 5 Glypican-1 Glypican-3 Heparanase 2 (inactive) Heparanase Iduronate 2-sulfatase N-acetyl-alpha-glucosaminidase N-sulfoglucosamine sulfohydrolase Syndecan-1 Syndecan-2 Syndecan	A0A3Q1LN81 A0A3Q1LRF3 A0A3Q1LTY7 A0A3Q1LZ29 A0A3Q1NAQ3 A0A3Q1NDQ7 A3KMY8 E1BCP9 E1BFX4 E1BKJ2 E1BKS1 F1MCX1 F1MY73 F1MZX8 F1N1G1 F1N2D5 Q08DZ5 Q3ZBZ6 Q58DD4	AGRN GLB1 GLB1L GLB1L2 GPC1 GPC2 GPC3 GPC4 GPC5 GUSB HPSE HPSE2 IDS IDUA NAGLU SDC1 SDC2 SDC4 SGSH	Bos taurus (cattle)	G01550VL G09546QO
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	Autocrine motility factor receptor Derlin-1 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Polyubiquitin-B Polyubiquitin-C Transitional endoplasmic reticulum ATPase UBX domain-containing protein 1 UV excision repair protein RAD23 homolog B Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	A0A3Q1LKK4 E1BE05 E1BKB2 G3X757 P0CG53 P0CH28 P62992 P63048 Q29RK4 Q32KW2 Q71SS4	AMFR DERL1 ENGASE NGLY1 RAD23B RPS27A SAKS1 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBXN1 VCP	Bos taurus (cattle)	G03934XO G25577BM G28233ME G51034LA G86419OL

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