GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **557** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
Interleukin-12 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 12 receptor subunit beta 2 Interleukin-12 subunit alpha Interleukin-12 subunit beta Protein disulfide-isomerase Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	A0A3Q1LXM0 E1BCP6 F1MCX4 F1MEB5 F1N0D6 F1N0R2 F6Q9Q9 G3MX29 P54349	IL12A IL12B IL12RB1 IL12RB2 JAK1 JAK2 P4HB STAT4 TYK2	Bos taurus (cattle)
Regulation of IFNG signaling	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Protein inhibitor of activated STAT 1 Rad60/SUMO-like domain-containing protein Rad60/SUMO-like domain-containing protein Signal transducer and activator of transcription Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A3Q1LLQ7 A0A3Q1M2W5 A0A3Q1ME65 A0A3Q1ML58 A0A3Q1MPM2 E1BCP6 F1MSN0 F1MXR5 F1N0D6 G3MZL6 P07353 Q9BEG9	IFNG IFNGR1 IFNGR2 JAK1 JAK2 PIAS1 PTPN2 SOCS1 SOCS3 STAT1	Bos taurus (cattle)
IFNG signaling activates MAPKs	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	A0A3Q1LLQ7 E1B8P9 E1BCP6 F1MXR5 F1N0D6 P07353 P46196	ERK2 IFNG IFNGR1 IFNGR2 JAK1 JAK2 MAPK1 MAPK3 PRKM1	Bos taurus (cattle)
Regulation of IFNA/IFNB signaling	Interferon 1AG1 Interferon 1AG8 Interferon alpha G Interferon alpha and beta receptor subunit 2 Interferon alpha/beta receptor 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A3Q1LPD3 A0A3Q1M739 A0A3Q1ME65 A0A3Q1MMI8 A6QQN2 E1B7E8 E1B8Z4 E1BDZ1 F1MCX4 F1MXT2 F1N0D6 F1N339 F1N6A7 G3MYH9 Q04790	IF1AG1 IF1AG8 IFNAC IFNAR IFNAR1 IFNAR2 JAK1 LOC100335490 LOC523244 LOC618947 LOC783912 PTPN1 PTPN11 PTPN6 STAT1 STAT2 TYK2	Bos taurus (cattle)
Laminin interactions	Integrin alpha-3 Integrin beta Integrin beta Integrin subunit alpha 6 Integrin subunit alpha 7 Laminin subunit alpha 4 Multiple EGF like domains 6 NID1 protein	A0A140T8D2 A0A3Q1M8K4 A0A3Q1MJT5 A0A3Q1MRM3 A0A3Q1N9E9 A6QNS6 E1BGA0 F1MMS9	ITGA3 ITGA6 ITGA7 ITGB1 ITGB4 LAMA4 MEGF6 NID1	Bos taurus (cattle)
TP53 Regulates Transcription of Death Receptors and Ligands	Insulin-like growth factor-binding protein 3 receptor Insulin-like growth factor-binding protein 3	P20959 Q1JQE1	IGFBP3 TMEM219	Bos taurus (cattle)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	G1K218 P07455 P07456	IGF1 IGF1R IGF2	Bos taurus (cattle)
Signaling by Insulin receptor	Insulin Tyrosine-protein kinase receptor	A5PJB2 F1MV64	INS INSR	Bos taurus (cattle)
IRS-mediated signalling	Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform phosphatidylinositol-4,5-bisphosphate 3-kinase	F1MJE0 F1MYE0 F1MYM3 P23726 P23727 P32871	IRS1 IRS2 PIK3CA PIK3CB PIK3R1 PIK3R2	Bos taurus (cattle)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	F1MGG8 F1MJE0 F1MYE0 G1K218 P07455 P07456	IGF1 IGF1R IGF2 IRS1 IRS2 IRS4	Bos taurus (cattle)
Elevation of cytosolic Ca2+ levels	Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor P2X purinoceptor 4 P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Short transient receptor potential channel 6 Transient receptor potential cation channel subfamily C member 3 Transient receptor potential cation channel subfamily C member 7	A0A3Q1LTG6 A0A3Q1M4W2 A0A3Q1N7P8 E1B742 E1BIH1 E1BIP1 E1BKE7 F1MUF3 F1MVZ6 F1MX21 F1N7A9 Q5E9U1 Q9MYW0	ITPR1 ITPR2 ITPR3 P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 TRP6 TRPC3 TRPC6 TRPC7	Bos taurus (cattle)
SUMOylation of immune response proteins	Inhibitor of nuclear factor kappa B kinase subunit epsilon NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) NF-kappaB transcription factor p65 subunit NFKB2 protein PIAS3 protein PIAS4 protein RING-type E3 ubiquitin transferase Rad60/SUMO-like domain-containing protein Rad60/SUMO-like domain-containing protein SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 3	A0A3Q1LUL4 A0A3Q1M2W5 A1XG22 A4FV15 A6QQU9 A7MBB7 F1MQ36 F1N329 G3MZL6 Q17QV3 Q8WNW7 Q95KU9	IKBKE IKBKG NEMO NFKB2 NFKBIA PIAS3 PIAS4 RELA SUMO3 TOPORS bIkBa	Bos taurus (cattle)
Costimulation by the CD28 family	Inducible T cell costimulator ligand Inducible T-cell costimulator Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3	E1BCU8 F1MDQ5 P23726 P23727 P32871 Q58DF9	ICOS ICOSLG PIK3CA PIK3R1 PIK3R2 PIK3R3	Bos taurus (cattle)
Metal ion SLC transporters	Hephaestin Natural resistance-associated macrophage protein 1 Solute carrier family 11 member 2 Solute carrier family 30 member 10 Solute carrier family 40 member Solute carrier family 41 member Solute carrier family 41 member ferroxidase	A0A3Q1MRJ4 A0JNB7 E1BAX4 E1BG51 F1MJ63 F1N076 G3MXE7 G3X6F6	CP HEPH SLC11A1 SLC11A2 SLC30A10 SLC40A1 SLC41A1 SLC41A2	Bos taurus (cattle)
The NLRP3 inflammasome	Heat shock protein HSP 90-beta NACHT, LRR and PYD domains-containing protein 3 P2X purinoceptor PYD and CARD domain containing Pannexin Proline-serine-threonine phosphatase interacting protein 1 Protein SGT1 homolog Thioredoxin-interacting protein Thioredoxin	A0A3Q1N8Q0 A6QLE5 A7Z054 D7R519 F1MQF6 F1MVZ6 O97680 Q2KIK0 Q76LV1	HSP90AB1 HSPC3 HSPCB NLRP3 P2RX7 PANX PANX1 PSTPIP1 PYCARD SUGT1 TXN TXNIP	Bos taurus (cattle)
Sema3A PAK dependent Axon repulsion	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta LIM domain kinase 1 Neuropilin Plexin A1 Plexin A2 Plexin A3 Plexin A4 Semaphorin 3A Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 3 Tyrosine-protein kinase Fyn Tyrosine-protein kinase non-specific serine/threonine protein kinase	A0A3Q1LSY0 A0A3Q1M0G8 A0JNB0 E1BC64 E1BFR4 E1BMX5 F1MEW1 F1MIH8 F1N173 F1N2P7 Q08E52 Q5E9H3 Q76LV1 Q76LV2	FES FYN HSP90A HSP90AA1 HSP90AB1 HSPC3 HSPCA HSPCB LIMK1 NRP1 PAK1 PAK2 PAK3 PLXNA1 PLXNA2 PLXNA3 PLXNA4 SEMA3A	Bos taurus (cattle)
DDX58/IFIH1-mediated induction of interferon-alpha/beta	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Interferon regulatory factor 3 Mitochondrial antiviral signaling protein TANK binding kinase 1 Translocase of outer mitochondrial membrane 70	A0A3Q1MIH6 E1BKP4 Q08E34 Q4JF28 Q76LV1 Q76LV2	HSP90A HSP90AA1 HSP90AB1 HSPC3 HSPCA HSPCB IRF3 MAVS TBK1 TOMM70 TOMM70A Tom70	Bos taurus (cattle)
Transferrin endocytosis and recycling	HFE Mucolipin TRP cation channel 1 STEAP3 metalloreductase STEAP4 metalloreductase Serotransferrin Transferrin receptor 2 Transferrin receptor protein 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase proteolipid subunit V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit S1 V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit	A0A3Q1LPT9 A0A3Q1MS24 A0A452DI38 A0A452DJ67 A4IFJ9 E1BGJ7 E1BIG6 E1BJW2 E1BMV6 F1MF47 G3MY82 G3X6N3 O46563 O97681 P11019 P21282 P31404 P31407 P31408 P40682 P61420 P79251 P81103 Q0VCV6 Q1RMS1 Q28029 Q2KJB6 Q2TA24 Q32LB7 Q5EEZ1	ATP6A1 ATP6AP1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6G ATP6G1 ATP6H ATP6IP1 ATP6N1B ATP6S1 ATP6S14 ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1E1 ATP6V1E2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H HFE LOC101904667 MCOLN1 STEAP3 STEAP4 TCIRG1 TF TFR2 TFRC VATC VATF VPATPD	Bos taurus (cattle)
Digestion	Guanylate cyclase activator 2B Guanylate cyclase Guanylin PIR protein alkaline phosphatase	A6QQH1 E1BIM0 E1BIM1 E1BJE3 F1N5B2	GUCA2A GUCA2B GUCY2C LOC516378 PIR	Bos taurus (cattle)
SHC-related events triggered by IGF1R	Growth factor receptor-bound protein 2 Insulin-like growth factor I Insulin-like growth factor II SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	F1N7C3 G1K218 P07455 P07456 Q0IIE2 Q3T0F9	GRB2 IGF1 IGF1R IGF2 SHC1 SOS1	Bos taurus (cattle)
Insulin receptor signalling cascade	Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 Insulin SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A3Q1LNN8 A5PJB2 F1MV64 F1N7C3 Q0IIE2 Q3T0F9	GRB10 GRB2 INS INSR SHC1 SOS1	Bos taurus (cattle)
Thyroxine biosynthesis	Glycoprotein hormones alpha chain Iodotyrosine deiodinase 1 NAD(P)H oxidase (H2O2-forming) NAD(P)H oxidase (H2O2-forming) Solute carrier family 5 member 5 Thyroid peroxidase Thyrotropin subunit beta	A0A3Q1M790 A0A3S5ZPC4 E1BMK1 E1BMS3 F1MT46 P01217 P01223	CGA DUOX1 DUOX2 IYD SLC5A5 TPO TSHB	Bos taurus (cattle)
Platelet Aggregation (Plug Formation)	Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Glycoprotein V platelet Prothrombin von Willebrand factor	A0A452DI66 E1B863 E1BG29 F1N0R5 F1N1G4	F2 GP1BB GP5 GP9 VWF	Bos taurus (cattle)
Glycerophospholipid catabolism	Glycerophosphocholine choline phosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1 Patatin like phospholipase domain containing 6	E1BMJ5 F1N5C8 Q3T0T0	ENPP6 GDE1 MIR16 PNPLA6	Bos taurus (cattle)
Electric Transmission Across Gap Junctions	Gap junction delta-2 protein Gap junction gamma-1 protein Gap junction protein Pannexin Pannexin	D7R519 E1BLU3 G5E5X7 Q2HJ66 Q866T7	GJA10 GJA7 GJA9 GJC1 GJD2 PANX PANX1 PANX2	Bos taurus (cattle)

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