GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **226 - 250** of **268** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
Serotonin receptors	5-hydroxytryptamine receptor 1A 5-hydroxytryptamine receptor 1B 5-hydroxytryptamine receptor 1D 5-hydroxytryptamine receptor 1E 5-hydroxytryptamine receptor 1F 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C 5-hydroxytryptamine receptor 4 5-hydroxytryptamine receptor 5A 5-hydroxytryptamine receptor 7 G-protein coupled receptors family 1 profile domain-containing protein	A0A8I3MN28 A0A8I3N6U6 A0A8I3NAA7 A0A8I3NLJ6 A0A8I3NMV4 A0A8I3PC67 A0A8I3RXP5 A0A8I3S1Q6 A0A8I3S5I1 A0A8I3S709 O46635 P79250	5-HTR2A HTR1B HTR1D HTR1E HTR1F HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7	Canis familiaris (dog)
Other interleukin signaling	Caspase-3 Colony stimulating factor 3 receptor Granulocyte colony-stimulating factor Interferon lambda receptor 1 Interleukin 29-like Interleukin 34 Macrophage colony-stimulating factor 1 Multifunctional fusion protein Pro-interleukin-16 Syndecan Syntaxin 4 Syntaxin-1A Syntaxin-binding protein 2 T-cell surface glycoprotein CD4 Taxilin alpha Tissue factor Tyrosine-protein kinase Tyrosine-protein kinase Vesicle-associated membrane protein 2 protein-tyrosine-phosphatase receptor protein-tyrosine kinase t-SNARE coiled-coil homology domain-containing protein	A0A8I3MKU0 A0A8I3MLF8 A0A8I3MP33 A0A8I3MU79 A0A8I3MWJ5 A0A8I3MXT5 A0A8I3NFS8 A0A8I3NN34 A0A8I3NNE2 A0A8I3NRN4 A0A8I3P3C6 A0A8I3P4F5 A0A8I3PNE3 A0A8I3PUZ4 A0A8I3Q7V8 A0A8I3QCQ2 A0A8I3RS40 A0A8I3S0X5 A0A8I3S6B0 A0A8I3S6J8 F1PS12 P33705	CASP3 CD4 CSF1 CSF1R CSF3 CSF3R IFNLR1 IL10RB IL16 IL29L IL34 JAK1 PTPRZ1 SDC1 SNAP25 STX1A STX3 STX4 STXBP2 TXLNA TYK2 VAMP2	Canis familiaris (dog)
Apoptotic cleavage of cell adhesion proteins	Cadherin-1 Cadherin-1 Caspase-3 Catenin beta-1 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein-3 Desmoplakin Occludin Plakophilin 1 Tight junction protein 1 Tight junction protein 2	A0A8I3MAQ1 A0A8I3NBM1 A0A8I3NIB1 A0A8I3NPT4 A0A8I3NRN4 A0A8I3NUM7 A0A8I3P212 A0A8I3RRA2 A0A8I3RW47 A0A8I3RY38 A0A8I3S0K7 F1PAA9 Q7YRU7	CASP3 CDH1 CTNNB1 DSG1 DSG2 DSG3 DSP OCLN PKP1 TJP1 TJP2	Canis familiaris (dog)
Peptide ligand-binding receptors	Adrenocorticotropic hormone receptor Angiotensinogen Atypical chemokine receptor 1 B1 bradykinin receptor B2 bradykinin receptor Bombesin receptor subtype-3 C3a anaphylatoxin chemotactic receptor C5a anaphylatoxin chemotactic receptor 1 Cholecystokinin Coagulation factor II thrombin receptor like 2 Complement C3 Complement C5 Complement C5a receptor 2 Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Endothelin-converting enzyme 1 F2R like thrombin or trypsin receptor 3 F2R like trypsin receptor 1 G protein-coupled receptor 37 like 1 G protein-coupled receptor 37 G-protein coupled estrogen receptor 1 Galanin peptides Galanin receptor 1 Galanin receptor 2 Galanin receptor 3 Gastrin releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Interleukin-8 KISS1 receptor Kappa-type opioid receptor Kell metallo-endopeptidase (Kell blood group) Kininogen 1 Kisspeptin Melanin concentrating hormone receptor 2 Melanin-concentrating hormone receptor 1 Melanocortin receptor 4 Melanocortin receptor 5 Melanocortin-3 receptor Motilin receptor Mu-type opioid receptor Multifunctional fusion protein Neurolysin, mitochondrial Neuromedin B receptor Neuromedin B Neuromedin U receptor 1 Neuromedin U receptor 2 Neuromedin-S Neuromedin-U-25 Neuropeptide B Neuropeptide S receptor 1 Neuropeptide S Neuropeptide W Neuropeptide Y receptor Y4 Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 2 Neuropeptide Y receptor type 5 Neuropeptide Y Neuropeptides B and W receptor 1 Neurotensin receptor 1 Neurotensin receptor 2 Neurotensin/neuromedin N Opioid receptor delta 1 Pancreatic polypeptide Peptide YY Pro-MCH Pro-opiomelanocortin Proenkephalin-A Proenkephalin-B Prokineticin 1 Prokineticin 2 Prokineticin receptor 1 Prolactin releasing hormone receptor Prolactin releasing hormone Promotilin Prosaposin Proteinase-activated receptor 1 Prothrombin Somatostatin receptor 3 Somatostatin receptor 5 Somatostatin receptor type 1 Somatostatin receptor type 2 Somatostatin Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor Type-2 angiotensin II receptor Uncharacterized protein Urotensin 2B Urotensin-2 receptor Urotensin-2 XK-related protein endothelin-converting enzyme 1	A0A0F6TN93 A0A8I3MA93 A0A8I3MC04 A0A8I3MHF9 A0A8I3MI39 A0A8I3MI44 A0A8I3MN59 A0A8I3MQK6 A0A8I3MQM8 A0A8I3MRG9 A0A8I3MRZ6 A0A8I3MU21 A0A8I3MU83 A0A8I3N0R9 A0A8I3N125 A0A8I3N427 A0A8I3N640 A0A8I3N6A0 A0A8I3NAD1 A0A8I3NAS6 A0A8I3ND24 A0A8I3NE44 A0A8I3NEI6 A0A8I3NFL3 A0A8I3NGZ9 A0A8I3NHY0 A0A8I3NPX3 A0A8I3NQ26 A0A8I3NQA0 A0A8I3NT15 A0A8I3NTL0 A0A8I3NVC1 A0A8I3NZA2 A0A8I3NZN3 A0A8I3P0A1 A0A8I3P108 A0A8I3P1U0 A0A8I3PBD4 A0A8I3PCM1 A0A8I3PFJ2 A0A8I3PIX9 A0A8I3PM36 A0A8I3PNM4 A0A8I3PT29 A0A8I3PT94 A0A8I3PUT1 A0A8I3PWE8 A0A8I3PYW9 A0A8I3Q0U9 A0A8I3Q141 A0A8I3Q2F2 A0A8I3Q2R9 A0A8I3Q3M6 A0A8I3Q5H2 A0A8I3Q615 A0A8I3Q8Q0 A0A8I3Q9F7 A0A8I3QB92 A0A8I3QEQ9 A0A8I3RQW9 A0A8I3RQX0 A0A8I3RQZ1 A0A8I3RR88 A0A8I3RT67 A0A8I3RTK9 A0A8I3RTX6 A0A8I3RVM8 A0A8I3RXC1 A0A8I3RZH5 A0A8I3S015 A0A8I3S0V2 A0A8I3S0Y6 A0A8I3S3Q7 A0A8I3S4W4 A0A8I3S6A4 A0A8I3S7S8 A0A8I3SBP0 B2NIZ6 B5TQW3 J9NWZ9 O02813 O62729 P10673 P12064 P13206 P30552 P41324 P49670 Q49LX5 Q4JIV8 Q5J7U3 Q5XXR2 Q8MIP6 Q9BDQ4 Q9BDQ5	ACKR1 AGT AGTR1 AGTR2 BDKRB1 BDKRB2 BRS3 Bdkrb2 C3 C3AR1 C5 C5AR1 C5AR2 CCK CCKBR CXCL8 ECE1 ECE2 EDN1 EDN2 EDN3 EDNRA EDNRB F2 F2R F2RL1 F2RL2 F2RL3 GAL GALR1 GALR2 GALR3 GPER1 GPR37 GPR37L1 GRP GRPR IL8 KEL KISS1R KNG1 Kiss1 MC2R MC3R MC4R MC5R MCH MCHR1 MCHR2 MLN MLNR MTLR NLN NMB NMBR NMS NMU NMUR1 NMUR2 NPB NPBWR1 NPS NPSR1 NPY NPY1R NPY2R NPY4R NPY5 NPY5R NTS NTSR1 NTSR2 OPRD1 OPRK1 OPRM1 PDYN PENK PMCH POMC PPY PRLH PRLHR PROK1 PROK2 PROKR1 PSAP PYY SST SSTR1 SSTR2 SSTR3 SSTR5 TRH TRHR UTS2B UTS2R XK	Canis familiaris (dog)
COX reactions	Prostaglandin G/H synthase 1	Q8HZR1	COX1 PTGS1	Canis familiaris (dog)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl peptidase 4 Free fatty acid receptor 1 Free fatty acid receptor 4 G protein subunit alpha transducin 3 G protein subunit gamma 13 G protein-coupled receptor 119 Gastrin-releasing peptide Glucagon Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Leptin	A0A8I3MH22 A0A8I3P5C5 A0A8I3PJF2 A0A8I3PQY2 A0A8I3Q958 A0A8I3QXE0 A0A8I3QZL6 A0A8I3RQW9 A0A8I3S964 P62872 P79147	DPP4 FFAR1 FFAR4 GCG GNAT3 GNB1 GNB3 GNG13 GPR119 GRP LEP	Canis familiaris (dog)	G58161NS
Ion homeostasis	ATP binding cassette subfamily C member 9 ATP-sensitive inward rectifier potassium channel 11 ATPase Na+/K+ transporting subunit alpha 3 Adenosylhomocysteinase like 1 Aspartate beta-hydroxylase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Cardiac phospholamban Chloride intracellular channel protein EF-hand domain-containing protein FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Nitric oxide synthase 1 Ryanodine receptor 1 Ryanodine receptor 2 Ryanodine receptor 3 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Short transient receptor potential channel 1 Sodium/calcium exchanger 1 Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Solute carrier family 8 member A2 Solute carrier family 8 member A3 Sorcin Stromal interaction molecule 1 Triadin Troponin I, cardiac muscle cAMP-dependent protein kinase catalytic subunit alpha calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase peptidylprolyl isomerase	A0A8I3M9N6 A0A8I3MFG9 A0A8I3MID3 A0A8I3MJQ7 A0A8I3MK29 A0A8I3MM26 A0A8I3MQA1 A0A8I3MRH3 A0A8I3MSQ7 A0A8I3MSS1 A0A8I3MT21 A0A8I3MTJ5 A0A8I3MXS3 A0A8I3NIS8 A0A8I3NKB2 A0A8I3NMP2 A0A8I3NNW7 A0A8I3NVA4 A0A8I3NYA8 A0A8I3P560 A0A8I3PCD4 A0A8I3PEN3 A0A8I3PJ46 A0A8I3PQA5 A0A8I3PRW9 A0A8I3PT17 A0A8I3PW88 A0A8I3PX80 A0A8I3Q281 A0A8I3Q2P2 A0A8I3Q886 A0A8I3Q8P6 A0A8I3QAS6 A0A8I3RSR2 A0A8I3RTF4 A0A8I3RVD4 A0A8I3RWC7 A0A8I3RWM0 A0A8I3RY81 A0A8I3S0A4 A0A8I3SBE1 A0A8I3SBK9 O46674 P23685 P61012 Q8MKD5	ABCC9 AHCYL1 ASPH ATP1A1 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 CALM2 CAMK2A CAMK2B CAMK2G CLIC2 FXYD1 FXYD2 FXYD3 FXYD4 FXYD6 FXYD7 ITPR1 ITPR2 ITPR3 KCNJ11 LOC119880472 NCX1 NOS1 PLN PRKACA RYR1 RYR2 RYR3 SLC8A1 SLC8A2 SLC8A3 SRI STIM1 TNNI3 TRDN TRPC1	Canis familiaris (dog)
Downstream TCR signaling	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 BCL10 immune signaling adaptor Caspase recruitment domain family member 11 Cullin 1 E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme F-box and WD repeat domain containing 11 Ig-like domain-containing protein IkappaB kinase Immunoglobulin V-set domain-containing protein Inhibitor of nuclear factor kappa-B kinase subunit alpha MALT1 paracaspase MHC class II DR alpha chain Major histocompatibility complex, class II, DQ alpha 1 Major histocompatibility complex, class II, DQ beta 2 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 10 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-8 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Protein kinase C RELA proto-oncogene, NF-kB subunit Receptor-interacting serine/threonine-protein kinase 2 S-phase kinase-associated protein 1 T cell receptor alpha variable 29/delta variable 5 T cell receptor associated transmembrane adaptor 1 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TNF receptor-associated factor 6 Tyrosine-protein kinase UBC core domain-containing protein Ubiquitin B Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3MED5 A0A8I3MFY1 A0A8I3MJ11 A0A8I3MJ82 A0A8I3MKK6 A0A8I3MKL4 A0A8I3MLM6 A0A8I3MMN5 A0A8I3MNA4 A0A8I3MNI0 A0A8I3MQX7 A0A8I3MR89 A0A8I3MU16 A0A8I3MUE2 A0A8I3MV98 A0A8I3MZ69 A0A8I3N0P1 A0A8I3N165 A0A8I3N3S4 A0A8I3N4F2 A0A8I3N5F1 A0A8I3N7L6 A0A8I3N952 A0A8I3N971 A0A8I3N9G3 A0A8I3NAC6 A0A8I3NFB9 A0A8I3NH42 A0A8I3NN65 A0A8I3NNJ9 A0A8I3NP41 A0A8I3NP66 A0A8I3NPT2 A0A8I3NPX1 A0A8I3NT57 A0A8I3NT75 A0A8I3NTK0 A0A8I3NUC6 A0A8I3NUK8 A0A8I3NW81 A0A8I3NXK9 A0A8I3P2V4 A0A8I3P3H3 A0A8I3P499 A0A8I3P4A1 A0A8I3P4Z1 A0A8I3P564 A0A8I3P6I7 A0A8I3P6M2 A0A8I3PAB8 A0A8I3PAP4 A0A8I3PB85 A0A8I3PBB2 A0A8I3PCE5 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PF55 A0A8I3PF76 A0A8I3PFI5 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PMA2 A0A8I3PR42 A0A8I3PWT3 A0A8I3PZT2 A0A8I3QV78 A0A8I3QYD0 A0A8I3RR14 A0A8I3RRK6 A0A8I3RRL7 A0A8I3RRR7 A0A8I3RT39 A0A8I3RXV3 A0A8I3RZF7 A0A8I3RZP6 A0A8I3S023 A0A8I3S1Z6 A0A8I3S2N1 A0A8I3S3J5 A0A8I3S3N2 A0A8I3S6C6 A0A8I3S6Q5 A0A8I3S792 E2R2I5 P27597 P33705 P60483 P63050 Q5W412 Q5W416 Q6F3J0	BCL10 CARD11 CD247 CD3D CD3E CD3G CD4 CDC34 CHUK CUL1 DLA-DQA1 DLA-DRA FBXW11 HLA-DQB2 IKBKB IKBKG INPP5D LCK LOC100686569 LOC100687259 LOC119881719 LOC610717 MALT1 MAP3K7 MMAC1 NFKB1 NFKBIA PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKCQ PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 PTEN RELA RIPK2 RPS27A SKP1 TAB2 TRAF6 TRAT1 TRAV29DV5 UBA52 UBB UBC UBCEP2 UBE2D1 UBE2D2 UBE2N	Canis familiaris (dog)
Gluconeogenesis	Beta-enolase Enolase 4 Fructose-1,6-bisphosphatase 1 Fructose-1,6-bisphosphatase isozyme 2 Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase Glucose-6-phosphatase Glucose-6-phosphatase Glucose-6-phosphatase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Phosphoglycerate kinase Phosphoglycerate kinase Phosphoglycerate mutase Phosphoglycerate mutase Pyruvate carboxylase Solute carrier family 37 member 1 Solute carrier family 37 member 2 Solute carrier family 37 member 4 Triosephosphate isomerase phosphoenolpyruvate carboxykinase (GTP) phosphopyruvate hydratase phosphopyruvate hydratase	A0A8I3MHK0 A0A8I3MJP4 A0A8I3MKD5 A0A8I3MKW3 A0A8I3MS60 A0A8I3MWF0 A0A8I3MZQ1 A0A8I3N1E7 A0A8I3N4J1 A0A8I3N504 A0A8I3ND17 A0A8I3NII5 A0A8I3NKZ1 A0A8I3NMJ6 A0A8I3P2U1 A0A8I3P9Y9 A0A8I3PK19 A0A8I3PRM7 A0A8I3PU48 A0A8I3PZE8 A0A8I3Q5N9 A0A8I3Q5Z0 A0A8I3QWQ0 A0A8I3RRW0 A0A8I3RTJ7 A0A8I3RYI2 A0A8I3S286 A0A8I3SC19	ALDOA ALDOB ALDOC ENO2 ENO3 ENO4 FBP1 FBP2 G6PC1 G6PC2 G6PC3 GAPDH GAPDHS GPI LOC106558132 PC PCK1 PCK2 PGAM1 PGAM2 PGK1 PGK2 SLC37A1 SLC37A2 SLC37A4 TPI1	Canis familiaris (dog)	G58161NS
G alpha (q) signalling events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B 5-hydroxytryptamine receptor 2C Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Amyloid-beta A4 protein Angiotensinogen Annexin Appetite-regulating hormone Arginine vasopressin B1 bradykinin receptor B2 bradykinin receptor Bombesin receptor subtype-3 Cholecystokinin Coagulation factor II thrombin receptor like 2 Cysteinyl leukotriene receptor 1 Cysteinyl leukotriene receptor 2 Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Extracellular calcium-sensing receptor F2R like thrombin or trypsin receptor 3 F2R like trypsin receptor 1 Free fatty acid receptor 1 Free fatty acid receptor 1 Free fatty acid receptor 2 Free fatty acid receptor 4 G protein subunit beta 2 G protein subunit beta 4 G protein subunit gamma 13 G protein-coupled receptor 143 G protein-coupled receptor 17 G protein-coupled receptor 68 G protein-coupled receptor kinase G-protein coupled receptor family C group 6 member A G-protein coupled receptors family 1 profile domain-containing protein G-protein coupled receptors family 1 profile domain-containing protein Gastrin releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Gastrin Glucagon receptor Glucagon Glutamate metabotropic receptor 1 Glutamate metabotropic receptor 5 Gonadotropin-releasing hormone receptor Growth hormone secretagogue receptor type 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(q) subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Histamine H1 receptor Hypocretin neuropeptide precursor KISS1 receptor Kininogen 1 Kisspeptin Leukotriene B4 receptor 2 Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 3 Lysophosphatidic acid receptor 4 Lysophosphatidic acid receptor 5 Melanin concentrating hormone receptor 2 Melanin-concentrating hormone receptor 1 Melanopsin Motilin receptor Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor Neuromedin B receptor Neuromedin B Neuromedin U receptor 1 Neuromedin U receptor 2 Neuromedin-K receptor Neuromedin-K Neuromedin-S Neuromedin-U-25 Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Neuropeptide S receptor 1 Neuropeptide S Neurotensin receptor 1 Neurotensin receptor 2 Neurotensin/neuromedin N Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Oxytocin receptor Oxytocin-neurophysin 1 P2Y purinoceptor 1 P2Y purinoceptor 2 P2Y receptor family member 10 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Platelet-activating factor receptor Pro-MCH Progonadoliberin Prokineticin 1 Prokineticin 2 Prokineticin receptor 1 Promotilin Prostaglandin E2 receptor EP1 subtype Prostaglandin F2-alpha receptor Protachykinin-1 Proteinase-activated receptor 1 Prothrombin Purinergic receptor P2Y11 Pyrimidinergic receptor P2Y6 Pyroglutamylated RFamide peptide receptor Pyroglutamylated RFamide peptide Regulator of G protein signaling 13 Regulator of G protein signaling 17 Regulator of G protein signaling 18 Regulator of G protein signaling 19 Regulator of G protein signaling 21 Regulator of G protein signaling 3 Regulator of G protein signaling 5 Regulator of G protein signaling like 1 Regulator of G-protein signaling 16 Regulator of G-protein signaling 1 Regulator of G-protein signaling 2 Regulator of G-protein signaling 4 Rho guanine nucleotide exchange factor 25 Substance-K receptor Substance-P receptor Thromboxane A2 receptor Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Urotensin 2B Urotensin-2 receptor Urotensin-2 Vasopressin V1a receptor Vasopressin V1b receptor non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3M9P4 A0A8I3MBK3 A0A8I3ME07 A0A8I3MH22 A0A8I3MHA7 A0A8I3MIG1 A0A8I3MKF9 A0A8I3MKX3 A0A8I3MM75 A0A8I3MM87 A0A8I3MN59 A0A8I3MNZ2 A0A8I3MPF9 A0A8I3MPW0 A0A8I3MQB9 A0A8I3MRG9 A0A8I3MRI6 A0A8I3MSX9 A0A8I3MTW1 A0A8I3MU21 A0A8I3MYE3 A0A8I3MZ62 A0A8I3N081 A0A8I3N0R9 A0A8I3N125 A0A8I3N190 A0A8I3N2K3 A0A8I3N4T4 A0A8I3N4Y4 A0A8I3N5K9 A0A8I3N7G1 A0A8I3N8M9 A0A8I3N971 A0A8I3N9Q6 A0A8I3NAP0 A0A8I3NCM2 A0A8I3NE44 A0A8I3NE91 A0A8I3NEI6 A0A8I3NEL6 A0A8I3NFC7 A0A8I3NFE6 A0A8I3NFL3 A0A8I3NFV9 A0A8I3NHY0 A0A8I3NK63 A0A8I3NKP7 A0A8I3NL60 A0A8I3NN89 A0A8I3NPA7 A0A8I3NPM9 A0A8I3NPT8 A0A8I3NPX3 A0A8I3NQV1 A0A8I3NT15 A0A8I3NTE8 A0A8I3NX67 A0A8I3NZX3 A0A8I3P1U0 A0A8I3P519 A0A8I3P5C5 A0A8I3P7Z3 A0A8I3P9H6 A0A8I3PBE4 A0A8I3PBK9 A0A8I3PC67 A0A8I3PCA6 A0A8I3PCK7 A0A8I3PED5 A0A8I3PEX2 A0A8I3PFJ2 A0A8I3PH67 A0A8I3PJF2 A0A8I3PJM2 A0A8I3PL97 A0A8I3PLY8 A0A8I3PM36 A0A8I3PM57 A0A8I3PMD7 A0A8I3PN52 A0A8I3PPA3 A0A8I3PQK7 A0A8I3PS75 A0A8I3PTJ5 A0A8I3PTY7 A0A8I3PUT1 A0A8I3PV05 A0A8I3PVE7 A0A8I3PVZ2 A0A8I3PW94 A0A8I3PWB5 A0A8I3PWE8 A0A8I3PYW9 A0A8I3Q0U9 A0A8I3Q141 A0A8I3Q2R9 A0A8I3Q3G9 A0A8I3Q3M6 A0A8I3Q4W3 A0A8I3Q5H2 A0A8I3Q9F7 A0A8I3QB92 A0A8I3QBR1 A0A8I3QEQ9 A0A8I3QXE0 A0A8I3RQW9 A0A8I3RQZ1 A0A8I3RR88 A0A8I3RSX8 A0A8I3RTK7 A0A8I3RV82 A0A8I3RVA9 A0A8I3RX12 A0A8I3RXY8 A0A8I3RY80 A0A8I3RYN2 A0A8I3RZH5 A0A8I3S015 A0A8I3S0K5 A0A8I3S0V2 A0A8I3S0Y6 A0A8I3S1Q6 A0A8I3S2W1 A0A8I3S3N2 A0A8I3S3Q7 A0A8I3S4W4 A0A8I3S5G1 A0A8I3S6D4 A0A8I3S7S8 A0A8I3SAA7 A0A8I3SBJ6 A2SXS6 A5HKU8 B2NIZ6 E2R3W5 J9NWZ9 O46635 O97564 P01353 P10673 P12064 P13206 P30552 P62872 P63210 P79147 Q28294 Q45FN0 Q5DUB2 Q5DUB3 Q5J7U3 Q5XX73 Q5XXR2 Q8MIP6 Q9BDQ4 Q9BDQ5 Q9BEF8 Q9BGL8 Q9GLF6 Q9TUP7	5-HTR2A ADRA1A ADRA1B ADRA1D AGT AGTR1 ANXA1 APP ARHGEF25 AVP AVPR1A AVPR1B BDKRB1 BDKRB2 BRS3 BTK Bdkrb2 CASR CCK CCKBR CCL23 CHRM1 CHRM3 CHRM5 CYSLTR1 CYSLTR2 EDN1 EDN2 EDN3 EDNRA EDNRB F2 F2R F2RL1 F2RL2 F2RL3 FFAR1 FFAR2 FFAR4 FPR2 GAS GAST GCG GCGR GHRL GHSR GNA11 GNA14 GNA15 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG11 GNG13 GNG2 GNG3 GNG4 GNG8 GNGT1 GNGT2 GNRH1 GNRHR GPR132 GPR143 GPR17 GPR39 GPR68 GPRC6A GRK2 GRM1 GRM5 GRP GRPR HCRT HCRTR1 HCRTR2 HRH1 HTR2A HTR2B HTR2C KALRN KISS1R KNG1 Kiss1 LOC100856339 LOC116183080 LOC119863873 LOC119865171 LPAR1 LPAR2 LPAR3 LPAR4 LPAR5 LPAR6 LTB4R2 MCH MCHR1 MCHR2 MLN MLNR MTLR MTLRP NMB NMBR NMS NMU NMUR1 NMUR2 NPFFR1 NPFFR2 NPS NPSR1 NTS NTSR1 NTSR2 OPN4 OX OXT OXTR P2RY1 P2RY10 P2RY11 P2RY2 P2RY6 PIK3CA PIK3R1 PIK3R2 PLCB1 PLCB2 PLCB3 PLCB4 PMCH PPOX PROK1 PROK2 PROKR1 PTAFR PTGER1 PTGFR QRFP QRFPR RGS1 RGS13 RGS16 RGS17 RGS18 RGS19 RGS2 RGS21 RGS3 RGS4 RGS5 RGSL1 TAC1 TACR1 TACR2 TACR3 TBXA2R TRH TRHR UTS2B UTS2R XCR1	Canis familiaris (dog)
Orexin and neuropeptides FF and QRFP bind to their respective receptors	Hypocretin neuropeptide precursor Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Pyroglutamylated RFamide peptide receptor Pyroglutamylated RFamide peptide	A0A8I3PCA6 A0A8I3PCK7 A0A8I3RSX8 Q9GLF6 Q9TUP7	HCRT HCRTR1 HCRTR2 OX PPOX QRFP QRFPR	Canis familiaris (dog)
Clathrin-mediated endocytosis	ADP ribosylation factor GTPase activating protein 1 ADP-ribosylation factor 6 AP complex subunit beta AP-2 complex subunit alpha AP-2 complex subunit alpha AP-2 complex subunit mu AP-2 complex subunit sigma AP2 associated kinase 1 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit Actin-related protein 2 Actin-related protein 3 Adaptin ear-binding coat-associated protein 1 Amphiphysin Apolipoprotein B ArfGAP with FG repeats 1 Arginine vasopressin Arp2/3 complex 34 kDa subunit Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 Bridging integrator 1 Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein Clathrin heavy chain Clathrin heavy chain Clathrin light chain Clathrin light chain Cyclin G associated kinase Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator DAB adaptor protein 2 Dishevelled segment polarity protein 2 DnaJ heat shock protein family (Hsp40) member C6 E3 ubiquitin-protein ligase CBL EGF-like domain-containing protein Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 like 1 Epidermal growth factor receptor pathway substrate 15 Epiregulin Epsin 2 F-BAR domain only protein 2 FCH and mu domain containing endocytic adaptor 1 Formin binding protein 1 Formin-binding protein 1-like Frizzled-4 GTPase activating protein and VPS9 domains 1 Growth factor receptor bound protein 2 Heat shock cognate 71 kDa protein Hepatocyte growth factor-regulated tyrosine kinase substrate Huntingtin interacting protein 1 related Huntingtin interacting protein 1 Interleukin-7 receptor subunit alpha Intersectin 1 Intersectin 2 KIAA0319 LDL receptor related protein 2 Low density lipoprotein receptor adaptor protein 1 Low-density lipoprotein receptor Mannose-6-phosphate receptor, cation dependent Muscarinic acetylcholine receptor Phosphatidylinositol binding clathrin assembly protein Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Protein Wnt Protein kinase C and casein kinase substrate in neurons 1 Protein kinase C and casein kinase substrate in neurons 2 Protein kinase C and casein kinase substrate in neurons 3 Queuine tRNA-ribosyltransferase catalytic subunit 1 RALBP1 associated Eps domain containing 1 RALBP1 associated Eps domain containing 2 Ras-related protein Rab-5A Ras-related protein Rab-5C Receptor protein-tyrosine kinase SH3 domain containing GRB2 like 2, endophilin A1 SH3 domain containing kinase binding protein 1 Scavenger receptor class B member 2 Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Solute carrier family 18 member A3 Solute carrier family 2 member 8 Sorting nexin 18 Sorting nexin 9 Stonin-1 Stonin-2 Substance-P receptor Synaptosome associated protein 91 Synaptotagmin 11 Synaptotagmin 8 Synaptotagmin Synaptotagmin T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD4 Thyroid hormone receptor interactor 10 Trans-golgi network protein 2 Type-1 angiotensin II receptor Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vasopressin V2 receptor Vesicle associated membrane protein 4 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 3 Vesicle-associated membrane protein 7 Vesicle-associated membrane protein 8 WASP like actin nucleation promoting factor dynamin GTPase dynamin GTPase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase small monomeric GTPase	A0A8I3MAW6 A0A8I3MBG9 A0A8I3MBU4 A0A8I3MFQ5 A0A8I3MFY1 A0A8I3MIP1 A0A8I3MJ11 A0A8I3MJ91 A0A8I3MMN5 A0A8I3MNR2 A0A8I3MPK0 A0A8I3MPX3 A0A8I3MQ56 A0A8I3MQX2 A0A8I3MT64 A0A8I3MT80 A0A8I3MZG1 A0A8I3MZL3 A0A8I3N0H9 A0A8I3N156 A0A8I3N1F4 A0A8I3N1Q4 A0A8I3N1W7 A0A8I3N2E5 A0A8I3N2P0 A0A8I3N6A2 A0A8I3N7P9 A0A8I3N8J8 A0A8I3N8L8 A0A8I3N8T5 A0A8I3N970 A0A8I3NCI2 A0A8I3NCU8 A0A8I3ND55 A0A8I3NE45 A0A8I3NEW9 A0A8I3NF22 A0A8I3NFB9 A0A8I3NGD3 A0A8I3NH32 A0A8I3NHL8 A0A8I3NHV2 A0A8I3NIE0 A0A8I3NKR3 A0A8I3NLC1 A0A8I3NNW3 A0A8I3NPI2 A0A8I3NRM5 A0A8I3NS16 A0A8I3NTR3 A0A8I3NW16 A0A8I3NXQ1 A0A8I3NZC2 A0A8I3NZX3 A0A8I3P087 A0A8I3P562 A0A8I3P6R3 A0A8I3P953 A0A8I3P9Q7 A0A8I3PFJ2 A0A8I3PFM7 A0A8I3PGA9 A0A8I3PGB9 A0A8I3PGP9 A0A8I3PJG5 A0A8I3PK72 A0A8I3PKW5 A0A8I3PLP7 A0A8I3PMU1 A0A8I3PMU8 A0A8I3PP11 A0A8I3PPD9 A0A8I3PPQ5 A0A8I3PQE6 A0A8I3PSX7 A0A8I3PT69 A0A8I3PWA8 A0A8I3PZW5 A0A8I3Q052 A0A8I3Q065 A0A8I3Q2I4 A0A8I3Q314 A0A8I3Q374 A0A8I3Q3J5 A0A8I3Q545 A0A8I3Q5C2 A0A8I3Q5L9 A0A8I3QYD0 A0A8I3QZA5 A0A8I3RP69 A0A8I3RPS3 A0A8I3RR45 A0A8I3RR73 A0A8I3RTD0 A0A8I3RU23 A0A8I3RUF5 A0A8I3RUS6 A0A8I3RV18 A0A8I3RV68 A0A8I3RYJ5 A0A8I3RZ76 A0A8I3RZF8 A0A8I3S1H6 A0A8I3S1K9 A0A8I3S1V5 A0A8I3S360 A0A8I3S4D1 A0A8I3S565 A0A8I3S6J8 A0A8I3S7E5 A0A8I3S7Q4 A0A8I3S7X1 A0A8I3S9K7 A0A8I3SAF2 A0A8I3SAR3 B1H0W0 F1PHV6 P18066 P33705 P51147 P63050 Q5DUB3 Q5U820	AAK1 ABCC7 ACTR2 ACTR3 ADRB2 AGFG1 AGTR1 AMPH AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB AREG ARF6 ARFGAP1 ARPC1A ARPC2 ARPC3 ARPC4 ARPC5 ARRB1 ARRB2 AVP AVPR2 BIN1 BTC CBL CD3D CD3G CD4 CFTR CHRM2 CI-MPR/IGF2R CLTA CLTB CLTC CLTCL1 DAB2 DNAJC6 DNM1 DNM2 DNM3 DVL2 EGF EGFR EPGN EPN1 EPN2 EPS15 EPS15L1 EREG FCHO1 FCHO2 FNBP1 FNBP1L FZD4 GAK GAPVD1 GRB2 HBEGF HGS HIP1 HIP1R IGF2R IL7R ITSN2 KIAA0319 LDLR LDLRAP1 LOC102156511 LOC119867035 LOC607182 LRP2 M6PR NECAP1 NECAP2 OCRL PACSIN1 PACSIN2 PACSIN3 PICALM PIK3C2A PIP5K1C QTRT1 RAB5A RAB5B RAB5C REPS2 RPS27A SCARB2 SH3GL1 SH3GL2 SH3KBP1 SLC18A3 SLC2A8 SNAP91 SNX18 SNX9 STAM STAM2 STON1 STON2 SYNJ1 SYNJ2 SYT1 SYT11 SYT2 SYT8 TACR1 TGFA TGOLN2 TRIP10 UBA52 UBB UBC UBCEP2 VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 WASL WNT5A	Canis familiaris (dog)
Platelet Adhesion to exposed collagen	ADAM metallopeptidase with thrombospondin type 1 motif 13 High affinity immunoglobulin epsilon receptor subunit gamma Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein von Willebrand factor von Willebrand factor	A0A8I3N060 A0A8I3NAX6 A0A8I3P3X1 A0A8I3PUN0 A0A8I3QSK6 A0A8I3SCK0 Q28295	ADAMTS13 F8VWF FCER1G FYN GP6 LYN VWF	Canis familiaris (dog)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Glucose-6-phosphate 1-dehydrogenase Phosphoglucomutase 2 Ribokinase Ribulose-phosphate 3-epimerase Sedoheptulokinase Transaldolase Transketolase deoxyribose-phosphate aldolase ribose-5-phosphate isomerase	A0A8I3MQ54 A0A8I3MSC7 A0A8I3NN17 A0A8I3P237 A0A8I3P626 A0A8I3Q4Y1 A0A8I3Q7C5 A0A8I3RVI9 A0A8I3RZI7 A0A8I3S1Y7 A0A8I3SAK1	DERA G6PD PGD PGLS PGM2 RBKS RPE RPIA SHPK TALDO1 TKT	Canis familiaris (dog)	G31080DL
IFNG signaling activates MAPKs	Fibronectin type-III domain-containing protein Interferon gamma Mitogen-activated protein kinase Mitogen-activated protein kinase RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein	A0A8I3MY73 A0A8I3NVH4 A0A8I3PZA0 A0A8I3PZP0 A0A8I3QCJ0 A0A8I3RQD0 A0A8I3RS40 P42161	IFNG IFNGR1 IFNGR2 JAK1 JAK2 MAPK1 MAPK3 RAF1	Canis familiaris (dog)
Neurotransmitter receptors and postsynaptic signal transmission	5-hydroxytryptamine receptor 3A 5-hydroxytryptamine receptor 3B 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3C 5-hydroxytryptamine receptor 3E Glycine receptor alpha 1 Glycine receptor alpha 2 Glycine receptor alpha 3 Glycine receptor beta	A0A8I3MA77 A0A8I3MAG0 A0A8I3MZA4 A0A8I3NSZ3 A0A8I3P3M8 A0A8I3PQC9 A0A8I3Q2Z5 A0A8I3Q6S9 A0A8I3S5H9	GLRA1 GLRA2 GLRA3 GLRB HTR3A HTR3B HTR3C HTR3E LOC478649	Canis familiaris (dog)
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Uncharacterized protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NV07 A0A8I3PJY6 A0A8I3SAY5 A0A8I3SCI7 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 PLCG1	Canis familiaris (dog)
RHO GTPases regulate CFTR trafficking	Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator Golgi associated PDZ and coiled-coil motif containing Ras homolog family member Q	A0A8I3Q881 A0A8I3RUU0 A0A8I3RV68 Q5U820	ABCC7 CFTR GOPC RHOQ	Canis familiaris (dog)
O-linked glycosylation	Beta-1,4-glucuronyltransferase 1 Dolichyl-phosphate-mannose--protein mannosyltransferase Dolichyl-phosphate-mannose--protein mannosyltransferase Dystroglycan 1 Hexosyltransferase LARGE xylosyl- and glucuronyltransferase 1 LARGE xylosyl- and glucuronyltransferase 2 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 Protein O-mannose kinase	A0A8I3MY95 A0A8I3N4J0 A0A8I3NBQ3 A0A8I3NME9 A0A8I3NRN3 A0A8I3P5F6 A0A8I3P946 A0A8I3QJ22 Q5NDE9 Q9TSZ6	AGO61 B3GALNT2 B4GAT1 DAG1 GTDC2 LARGE1 LARGE2 POMGNT1 POMGNT2 POMK POMT1 POMT2	Canis familiaris (dog)
Arachidonic acid metabolism	Acyltransferase Phospholipase A2 fatty acid amide hydrolase	A0A8I3MZB9 A0A8I3P542 A0A8I3Q562	DGAT2L6 FAAH PLA2G4A	Canis familiaris (dog)
Phase 3 - rapid repolarisation	Potassium voltage-gated channel subfamily A member 5 Potassium voltage-gated channel subfamily E member 1 Potassium voltage-gated channel subfamily E member 2 Potassium voltage-gated channel subfamily E regulatory subunit 3 Potassium voltage-gated channel subfamily E regulatory subunit 5 Potassium voltage-gated channel subfamily H member 2 Uncharacterized protein	A0A8I3MYQ7 A0A8I3P4I4 A0A8I3PKK9 A0A8I3PME7 A0A8I3PYI8 A0A8I3SCN1 Q9TSZ3	CERG ERG KCNA5 KCNE2 KCNE3 KCNE4 KCNE5 KCNH2	Canis familiaris (dog)
Phase 0 - rapid depolarisation	Calcium voltage-gated channel auxiliary subunit alpha2delta 2 Calcium voltage-gated channel auxiliary subunit gamma 4 Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent calcium channel gamma-6 subunit Voltage-dependent calcium channel gamma-7 subunit Voltage-dependent calcium channel gamma-8 subunit	A0A8I3MK78 A0A8I3N7S8 A0A8I3NMX5 A0A8I3NPX9 A0A8I3P8U8 A0A8I3Q178 A0A8I3QY31 A0A8I3RTB9	CACNA1C CACNA2D2 CACNB1 CACNB2 CACNG4 CACNG6 CACNG7 CACNG8	Canis familiaris (dog)
Interleukin-2 signaling	Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 SHC-transforming protein 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase non-specific protein-tyrosine kinase	A0A8I3MVN6 A0A8I3N974 A0A8I3NAC6 A0A8I3NUU1 A0A8I3P3G0 A0A8I3RRY0 A0A8I3RS40 A0A8I3RVE7 A0A8I3RYS0 A0A8I3S4Z2 Q29416	IL2 IL2RA IL2RB JAK1 JAK3 LCK PTK2B SHC1 STAT5A STAT5B SYK	Canis familiaris (dog)
SHC-mediated cascade:FGFR3	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Uncharacterized protein small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3NHF3 A0A8I3NS74 A0A8I3NTD6 A0A8I3NUU1 A0A8I3NV07 A0A8I3PJY6 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 J9P0B3 J9P3I7 J9P8K0 Q20FD0	FGF1 FGF16 FGF17 FGF18 FGF20 FGF23 FGF3A FGF4 FGF4B FGF4C FGF5 FGF7A FGF8 FGF8B FGF9 FGFR3 GRB2 HRAS KRAS NRAS SHC1 SOS1	Canis familiaris (dog)
Response to elevated platelet cytosolic Ca2+	Protein kinase C Protein kinase C Protein kinase C	A0A8I3MI53 A0A8I3PUQ8 E2R2X3	PRKCA PRKCB PRKCG	Canis familiaris (dog)

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