GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source Last Updated
Reactome March 20, 2024
ECODAB April 1, 2019
Displaying entries 51 - 75 of 268 in total
Pathway Name Protein Name UniProt ID Gene Symbol Organism ▼ GlyTouCan ID
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
  • CBR1
  • COX-2
  • COX1
  • CYP8B1
  • H-PGDS
  • HPGDS
  • PGES
  • PTGDS
  • PTGES
  • PTGES2
  • PTGIS
  • PTGS1
  • PTGS2
  • TBXAS1
Canis familiaris (dog)
Toll Like Receptor 9 (TLR9) Cascade
  • EEA1
  • PIK3C3
  • PIK3R4
  • RBSN
  • TLR9
Canis familiaris (dog)
Presynaptic depolarization and calcium channel opening
  • CACNA1A
  • CACNA1E
  • CACNA2D2
  • CACNA2D3
  • CACNB1
  • CACNB2
  • CACNB3
  • CACNB4
  • CACNG2
  • CACNG4
Canis familiaris (dog)
MET activates PI3K/AKT signaling
  • GAB1
  • GRB2
  • HGF
  • MET
  • PIK3CA
  • PIK3R1
Canis familiaris (dog)
Adherens junctions interactions
  • AFDN
  • CADM1
  • CADM2
  • CADM3
  • CDH1
  • CDH10
  • CDH11
  • CDH12
  • CDH13
  • CDH15
  • CDH17
  • CDH18
  • CDH2
  • CDH24
  • CDH3
  • CDH4
  • CDH5
  • CDH6
  • CDH7
  • CDH8
  • CDH9
  • CTNNA1
  • CTNNB1
  • CTNND1
  • JUP
  • NECTIN1
  • NECTIN2
  • NECTIN3
  • NECTIN4
Canis familiaris (dog)
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
  • BGLAP
  • F10
  • F2
  • F7
  • F9
  • GAS6
  • PROC
  • PROS1
Canis familiaris (dog)
FGFR2c ligand binding and activation
  • FGF1
  • FGF16
  • FGF17
  • FGF18
  • FGF20
  • FGF23
  • FGF3A
  • FGF4
  • FGF4B
  • FGF4C
  • FGF5
  • FGF6
  • FGF7A
  • FGF7B
  • FGF8
  • FGF8B
  • FGF9
  • FGFR2
Canis familiaris (dog)
A tetrasaccharide linker sequence is required for GAG synthesis
  • AGRN
  • B3GALT6
  • B3GAT1
  • B3GAT2
  • B3GAT3
  • B4GALT7
  • BCAN
  • BGN
  • CSPG4
  • CSPG5
  • DCN
  • DCN1C
  • GPC1
  • GPC2
  • GPC3
  • GPC4
  • GPC5
  • GPC6
  • NCAN
  • SDC1
  • SDC3
  • SDC4
  • VCAN
  • XYLT1
  • XYLT2
Canis familiaris (dog)
Transport of bile salts and organic acids, metal ions and amine compounds
  • SLC10A6
  • SLC14A1
  • SLC14A2
  • SLC44A1
  • SLC44A2
  • SLC44A3
  • SLC44A4
  • SLC44A5
  • SLC47A1
  • SLC47A2
  • SLC5A7
Canis familiaris (dog)
Transcriptional and post-translational regulation of MITF-M expression and activity
  • AIMP1
  • AIMP2
  • CREBBP
  • DARS1
  • EEF1E1
  • EPRS1
  • GSK3B
  • IARS1
  • KARS1
  • KIT
  • KITLG
  • LARS1
  • LOC100684571
  • MAPK1
  • MAPK3
  • MARS1
  • MGF
  • MITF
  • QARS1
  • RARS1
  • RPS6KA1
  • WNT3A
  • XPO1
Canis familiaris (dog)
Synaptic adhesion-like molecules
  • DLG1
  • DLG3
  • DLG4
  • FLOT1
  • FLOT2
  • GRIA1
  • GRIA3
  • GRIA4
  • GRIN1
  • GRIN2A
  • GRIN2B
  • GRIN2C
  • GRIN2D
  • LRFN1
  • LRFN2
  • LRFN3
  • LRFN4
  • NMDAR1
  • PTPRD
  • PTPRF
  • RTN3
Canis familiaris (dog)
RHOQ GTPase cycle
  • ABCC7
  • ARHGAP1
  • ARHGAP17
  • ARHGAP21
  • ARHGAP26
  • ARHGAP32
  • ARHGAP33
  • ARHGAP35
  • ARHGAP5
  • ARHGEF7
  • ARL13B
  • CAV
  • CAV1
  • CDC42
  • CDC42BPA
  • CDC42BPB
  • CDC42EP1
  • CDC42EP2
  • CDC42EP3
  • CFTR
  • CPNE8
  • CXNK1
  • DEPDC1B
  • DIAPH3
  • DLC1
  • FNBP1
  • GFOD1
  • GIT1
  • GIT2
  • GJA1
  • GOPC
  • GRLF1
  • IQGAP3
  • JUP
  • LAMTOR1
  • LOC119867035
  • MPP7
  • OPHN1
  • P190A
  • PAK1
  • PAK2
  • PAK4
  • PLEKHG3
  • PREX1
  • RAB7
  • RAB7A
  • RHOQ
  • SCRIB
  • SLC1A5
  • SLC4A7
  • SNAP23
  • SRGAP2
  • STEAP3
  • STOM
  • SYDE1
  • TFRC
  • TRIP10
  • VAMP3
  • VANGL1
  • WASL
  • WWP2
  • p190ARHOGAP
Canis familiaris (dog)
The activation of arylsulfatases
  • ARSA
  • ARSB
  • ARSF
  • ARSG
  • ARSH
  • ARSI
  • ARSJ
  • ARSK
  • ARSL
  • STS
  • SUMF1
  • SUMF2
  • arsb
Canis familiaris (dog)
Cytoprotection by HMOX1
  • ABCC1
  • ALB
  • BLVRA
  • CARM1
  • CHD9
  • COX11
  • COX16
  • COX18
  • COX4I1
  • COX5A
  • COX5B
  • COX7A2L
  • CREBBP
  • CYC
  • CYCS
  • FABP1
  • GLNA2
  • GLNA3
  • HBQ1
  • HDAC3
  • HMOX1
  • HMOX2
  • LOC100682956
  • LOC100684983
  • LOC100688724
  • LOC119868178
  • LOC477508
  • LOC606860
  • LOC609402
  • LOC612644
  • LRPPRC
  • MED1
  • MRP1
  • NCOA1
  • NCOA2
  • NCOA6
  • NCOR1
  • NCOR2
  • PPARA
  • RXRA
  • SCO1
  • SCO2
  • SIN3A
  • SIN3B
  • SMARCD3
  • SURF1
  • TACO1
  • TBL1X
  • TBL1XR1
  • TGS1
Canis familiaris (dog)
EGFR Transactivation by Gastrin
  • EGFR
  • GRB2
  • HBEGF
  • HRAS
  • KRAS
  • MMP3
  • NRAS
  • PRKCA
  • SOS1
Canis familiaris (dog)
Thyroxine biosynthesis
  • CGA
  • DUOX1
  • DUOX2
  • GPA1
  • IYD
  • SLC5A5
  • THOX1
  • TPO
  • TSHB
Canis familiaris (dog)
MET activates STAT3
  • HGF
  • MET
  • STAT3
Canis familiaris (dog)
Interleukin-4 and Interleukin-13 signaling
  • GRP94
  • HSP90B1
  • HSPC4
  • IL13
  • IL13RA1
  • IL13RA2
  • IL4
  • IL4R
  • JAK1
  • JAK2
  • JAK3
  • SOCS5
  • STAT1
  • STAT3
  • STAT6
  • TRA1
  • TYK2
Canis familiaris (dog)
Lactose synthesis
  • B4GALT1
  • LALBA
  • LYZG
  • SLC2A1
Canis familiaris (dog)
Cellular hexose transport
  • FGF21
  • FGF8C
  • MFSD4B
  • SLC2A1
  • SLC2A10
  • SLC2A11
  • SLC2A12
  • SLC2A2
  • SLC2A3
  • SLC2A4
  • SLC2A6
  • SLC2A8
  • SLC2A9
  • SLC45A3
  • SLC50A1
  • SLC5A1
  • SLC5A10
  • SLC5A2
  • SLC5A4
  • SLC5A9
Canis familiaris (dog)
TRP channels
  • MCOLN1
  • MCOLN2
  • MCOLN3
  • TRPA1
  • TRPC1
  • TRPC3
  • TRPC4
  • TRPC4AP
  • TRPC5
  • TRPC6
  • TRPC7
  • TRPM1
  • TRPM2
  • TRPM3
  • TRPM4
  • TRPM5
  • TRPM6
  • TRPM7
  • TRPM8
  • TRPV1
  • TRPV2
  • TRPV3
  • TRPV4
  • TRPV5
  • TRPV6
Canis familiaris (dog)
Eicosanoid ligand-binding receptors
  • OXER1
Canis familiaris (dog)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
  • B2M
  • C3
  • CD160
  • CD19
  • CD1A8
  • CD1B
  • CD1D
  • CD200
  • CD226
  • CD247
  • CD300E
  • CD300LF
  • CD300LG
  • CD34
  • CD3D
  • CD3E
  • CD3G
  • CD40
  • CD40L
  • CD40LG
  • CD81
  • CD8A
  • CD8B
  • CD96
  • CD99
  • CLEC2B
  • CLEC2D
  • CLEC4G
  • CRTAM
  • CXADR
  • DLA-12
  • DLA-79
  • DLA88
  • FCGR1A
  • HCST
  • ICAM1
  • ICAM2
  • ICAM3
  • ICAM4
  • ICAM5
  • ITGA4
  • ITGAL
  • ITGB1
  • ITGB2
  • ITGB7
  • JAML
  • KLRB1
  • KLRF1
  • KLRK1
  • LAIR1
  • LOC100683099
  • LOC100686511
  • LOC102152131
  • LOC119863908
  • LOC119864110
  • LOC119864112
  • LOC119864113
  • LOC119864114
  • LOC119868795
  • LOC119873404
  • LOC119876868
  • LOC119881386
  • LOC475935
  • LOC476396
  • LOC483396
  • LOC484343
  • LOC606890
  • LOC609800
  • MADCAM1
  • MAG
  • NCR3
  • NCR3LG1
  • NECTIN2
  • NPDC1
  • OSCAR
  • PIANP
  • PILRA
  • PVR
  • SELL
  • SIGLEC1
  • SIGLEC11
  • SLAMF7
  • TNFSF5
  • TRAV29DV5
  • TREM1
  • TREML2
  • VCAM1
Canis familiaris (dog)
GRB2:SOS provides linkage to MAPK signaling for Integrins
  • APBB1IP
  • F8VWF
  • FN1
  • GRB2
  • ITGA2B
  • ITGB3
  • PTK2
  • RAP1A
  • RAP1B
  • SOS1
  • SRC
  • TLN1
  • VWF
Canis familiaris (dog)
The NLRP3 inflammasome
  • HSP90AB1
  • MEFV
  • NLRP3
  • P2RX7
  • PANX
  • PANX1
  • PSTPIP1
  • PYCARD
  • SUGT1
  • TXN
  • TXNIP
Canis familiaris (dog)

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024