GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **126 - 150** of **268** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Platelet degranulation	ATP binding cassette subfamily C member 4 Actin gamma 1 Actin, cytoplasmic 2 Actinin alpha 2 Actinin alpha 4 Albumin Alpha 1 antitrypsin Alpha-1-B glycoprotein Alpha-1-acid glycoprotein Alpha-2-HS-glycoprotein Alpha-2-macroglobulin Alpha-actinin-1 Amyloid beta precursor like protein 2 Amyloid-beta A4 protein Annexin Apolipoprotein A-I Beta-2-glycoprotein 1 Bromodomain and PHD finger containing 3 CD109 molecule CYFIP related Rac1 interactor B Cathepsin W Chitinase domain-containing protein 1 Clusterin Coagulation factor V Coagulation factor XIII A chain Complement factor D EF-hand domain-containing protein Endonuclease domain containing 1 Extracellular matrix protein 1 FERM domain containing kindlin 3 Fibronectin Fructose-bisphosphate aldolase GTP binding protein 2 Galectin-3-binding protein Growth arrest specific 6 Hepatocyte growth factor Histidine-rich glycoprotein Hsp90 co-chaperone Cdc37-like 1 Hyaluronan binding protein 4 Immunoglobulin superfamily containing leucine rich repeat Insulin-like growth factor I Insulin-like growth factor II Integrin beta Integrin subunit alpha 2b Inter-alpha-trypsin inhibitor heavy chain 4 Inter-alpha-trypsin inhibitor heavy chain H3 Kininogen 1 LHFPL tetraspan subfamily member 2 Left-right determination factor Lymphocyte antigen 6 family member G6F Lysosomal associated membrane protein 2 MICOS complex subunit Mesencephalic astrocyte derived neurotrophic factor Metalloproteinase inhibitor 1 Metalloproteinase inhibitor 3 NADH-cytochrome b5 reductase NHL repeat containing 2 Obg-like ATPase 1 Phosphatase and actin regulator Plasminogen activator inhibitor 1 Plasminogen Platelet and endothelial cell adhesion molecule 1 Platelet glycoprotein 4 Platelet-derived growth factor (PDGF) family profile domain-containing protein Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pleckstrin Prenylcysteine oxidase 1 like Pro-epidermal growth factor Pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) Prosaposin Protein FAM3C Protocadherin 7 Retinoic acid receptor responder protein 2 SPARC Saccharopine dehydrogenase-like oxidoreductase Secreted phosphoprotein 24 Secretogranin-3 Selectin P Selenoprotein P Serglycin Serpin family A member 3 Serpin family A member 4 Serpin family F member 2 Serpin family G member 1 Sulfhydryl oxidase Superoxide dismutase [Cu-Zn] Synaptotagmin like 4 Syntaxin-binding protein 2 TGF-beta family profile domain-containing protein Talin 1 Testis expressed 264, ER-phagy receptor Tetraspanin Tetraspanin Thrombospondin 1 Thymosin beta Transforming growth factor beta-3 proprotein Transforming growth factor beta Transforming growth factor beta Transgelin Tubulin alpha chain Uncharacterized protein Uncharacterized protein Vascular endothelial growth factor C Vascular endothelial growth factor D Vascular permeability factor Vinculin Vitamin K-dependent protein S WD repeat domain 1 protein disulfide-isomerase t-SNARE coiled-coil homology domain-containing protein von Willebrand factor von Willebrand factor	A0A0F7RNT6 A0A5F4D8V4 A0A8I3MDS4 A0A8I3MET0 A0A8I3MF27 A0A8I3MFB3 A0A8I3MIF9 A0A8I3MJD4 A0A8I3MJP4 A0A8I3MJV1 A0A8I3MLH1 A0A8I3MN98 A0A8I3MQM2 A0A8I3MQM8 A0A8I3MSG4 A0A8I3MSQ7 A0A8I3MWF4 A0A8I3MY68 A0A8I3MZY7 A0A8I3N024 A0A8I3N083 A0A8I3N1P4 A0A8I3N1U1 A0A8I3N2E8 A0A8I3N2K8 A0A8I3N3Q6 A0A8I3N493 A0A8I3N6K0 A0A8I3N7J4 A0A8I3N7S1 A0A8I3N9N1 A0A8I3NBJ3 A0A8I3ND38 A0A8I3NDE6 A0A8I3NDZ2 A0A8I3NE73 A0A8I3NEF4 A0A8I3NGI3 A0A8I3NI15 A0A8I3NIC8 A0A8I3NLI1 A0A8I3NMA5 A0A8I3NME3 A0A8I3NN14 A0A8I3NT28 A0A8I3NT63 A0A8I3NTB5 A0A8I3NV71 A0A8I3NX84 A0A8I3NZD4 A0A8I3P0H8 A0A8I3P3Z6 A0A8I3P5H2 A0A8I3P5J8 A0A8I3P5P0 A0A8I3P9H6 A0A8I3PCH7 A0A8I3PED8 A0A8I3PET9 A0A8I3PFD7 A0A8I3PIK8 A0A8I3PJ66 A0A8I3PM36 A0A8I3PMB5 A0A8I3PMU9 A0A8I3PPU8 A0A8I3PQB4 A0A8I3PQP6 A0A8I3PQY3 A0A8I3PSD1 A0A8I3PUZ4 A0A8I3PZZ6 A0A8I3Q1H9 A0A8I3Q1K1 A0A8I3Q1S9 A0A8I3Q4A4 A0A8I3Q4H4 A0A8I3Q4P5 A0A8I3Q5H9 A0A8I3Q5L9 A0A8I3Q5W3 A0A8I3Q7Y3 A0A8I3Q895 A0A8I3QAV8 A0A8I3QNS0 A0A8I3QUR2 A0A8I3RPA5 A0A8I3RQK1 A0A8I3RQL9 A0A8I3RSP7 A0A8I3RT50 A0A8I3RTY1 A0A8I3RUX2 A0A8I3RVR5 A0A8I3S1P1 A0A8I3S1V7 A0A8I3S1X8 A0A8I3S309 A0A8I3S396 A0A8I3S7S1 A0A8I3SCC7 A0A8I3SCD6 A0A8I3SCK0 A0A8I3SCT4 A1ILJ0 B8K1W7 P25473 P33703 P33712 Q28295 Q6Q308 Q6Q7I7 Q867B7	A1BG A2M ABCC4 ACTG1 ACTN1 ACTN2 AHSG ALB ALDOA ANXA5 APLP2 APOA1 APOH APOOL APP Abcc4 B9D2 BRPF3 CALM2 CANT1 CD109 CD36 CD63 CD9 CDC37L1 CFD CHID1 CLU CTSW CYB5R1 CYRIB ECM1 EGF ENDOD1 F13A1 F5 F8VWF FAM3C FERMT3 FLNA FN1 GAS6 GTPBP2 HABP4 HGF HRG IGF1 IGF2 IGFIA ISLR ITGA2B ITGB3 ITIH3 ITIH4 KNG1 LAMP2 LEFTY1 LGALS7B LHFPL2 LOC100685620 LOC102152706 LOC119866770 LOC490387 LY6G6F MAGED2 MANF NHLRC2 OLA1 PCDH7 PCYOX1L PDGFA PDGFB PECAM1 PHACTR2 PLEK PLG PPBP PROS1 PSAP QSOX1 RARRES2 SCCPDH SCG3 SELENOP SELP SERPINA1 SERPINA3 SERPINA4 SERPINE1 SERPINF2 SERPING1 SOD1 SPARC SPP2 SRGN STXBP2 SYTL4 TAGLN2 TEX264 TGFB2 TGFB3 THBS1 TIMP1 TIMP3 TLN1 TMX3 TUBA4A VCL VEGFA VEGFB VEGFC VEGFD VWF WDR1	Canis familiaris (dog)
Glycerophospholipid biosynthesis	Acylglycerol kinase, mitochondrial Copine 3 Copine 7	A0A8I3PCG6 A0A8I3Q635 F1P6M8	AGK CPNE3 CPNE7	Canis familiaris (dog)
Regulation of Complement cascade	C3a anaphylatoxin chemotactic receptor C4a anaphylatoxin C5a anaphylatoxin chemotactic receptor 1 CD19 molecule Carboxypeptidase B2 Carboxypeptidase N subunit 1 Carboxypeptidase N subunit 2 Clusterin Complement C1q B chain Complement C1q C chain Complement C1q subcomponent subunit A Complement C1s Complement C2 Complement C3 Complement C5 Complement C5a receptor 2 Complement C7 Complement C8 alpha chain Complement C8 gamma chain Complement component C6 Complement component C8 beta chain Complement component C9 Complement factor B Complement factor I Elastase, neutrophil expressed Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MAC-inhibitory protein Membrane cofactor protein Prothrombin Serpin family G member 1 Sushi domain-containing protein Sushi domain-containing protein Sushi domain-containing protein Sushi domain-containing protein Tetraspanin Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vitronectin complement subcomponent C1r	A0A8I3MAL2 A0A8I3MBH0 A0A8I3MDV8 A0A8I3MFV5 A0A8I3MKD7 A0A8I3MKJ7 A0A8I3MLF7 A0A8I3MPF4 A0A8I3MQ72 A0A8I3MQK6 A0A8I3MRL7 A0A8I3N180 A0A8I3N567 A0A8I3NC13 A0A8I3NH95 A0A8I3NLH3 A0A8I3NQA0 A0A8I3NQQ5 A0A8I3NT81 A0A8I3NVC1 A0A8I3NWR3 A0A8I3NYS7 A0A8I3P0T6 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P2N6 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P941 A0A8I3PD67 A0A8I3PDU9 A0A8I3PJQ7 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PTW0 A0A8I3PUA5 A0A8I3PUL5 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PUT1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3Q044 A0A8I3Q2F2 A0A8I3Q318 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3RQ73 A0A8I3RQX0 A0A8I3RSI3 A0A8I3RSN2 A0A8I3RUJ7 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S1V7 A0A8I3S6H5 A0A8I3S7V8 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 P25473 Q8MJD1	C1QA C1QB C1QC C1R C1S C2 C3 C3AR1 C5 C5AR1 C5AR2 C6 C7 C8A C8B C8G C9 CD19 CD55 CD59 CD81 CFB CFH CFHR5 CFI CLU CPB2 CPN1 CPN2 ELA2 ELANE F2 LOC102156626 LOC481722 LOC490269 SEBOX SERPING1	Canis familiaris (dog)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	B cell linker B-cell antigen receptor complex-associated protein alpha chain B-cell receptor CD22 CD19 molecule CD79a molecule CD79b molecule Cytoplasmic protein Dual adaptor of phosphotyrosine and 3-phosphoinositides 1 Growth factor receptor bound protein 2 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide phospholipase C Phosphoinositide-3-kinase adaptor protein 1 SH3 domain containing kinase binding protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Short transient receptor potential channel 1 Stromal interaction molecule 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vav guanine nucleotide exchange factor 1 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A8I3MIL9 A0A8I3MPF4 A0A8I3MUW4 A0A8I3N971 A0A8I3NA65 A0A8I3NKB2 A0A8I3NVL7 A0A8I3NWR3 A0A8I3NZG2 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P3G0 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P501 A0A8I3P6V2 A0A8I3P7Z3 A0A8I3P941 A0A8I3PD67 A0A8I3PDA6 A0A8I3PDU9 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PT69 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PW88 A0A8I3PWC6 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PY14 A0A8I3PYF1 A0A8I3Q1C3 A0A8I3Q281 A0A8I3Q2P2 A0A8I3Q525 A0A8I3Q5C2 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3RWM0 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S3D9 A0A8I3S602 A0A8I3S6H5 A0A8I3S960 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 P0CAN6	BLNK BTK CD19 CD79A CD79B DAPP1 GRB2 IGHM ITPR1 ITPR2 ITPR3 MAG NCK1 PIK3AP1 PIK3CD PIK3R1 PLCG2 PTPN6 SH3KBP1 SOS1 STIM1 SYK TRPC1 VAV1	Canis familiaris (dog)
Phase I - Functionalization of compounds	Aldehyde dehydrogenase, dimeric NADP-preferring Amine oxidase Amine oxidase Amine oxidase Aryl hydrocarbon receptor nuclear translocator 2 Aryl hydrocarbon receptor nuclear translocator Aryl hydrocarbon receptor repressor Aryl hydrocarbon receptor Arylacetamide deacetylase Biphenyl hydrolase like Carbonyl reductase (NADPH) Carboxylesterase 5A Carboxylic ester hydrolase Carboxymethylenebutenolidase homolog Cytochrome P450 2B11 Cytochrome P450 3A12 Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Cytochrome b5 heme-binding domain-containing protein Epoxide hydrolase N-ribosyldihydronicotinamide NADH-cytochrome b5 reductase 3 Uncharacterized protein	A0A8I3MQC6 A0A8I3MQJ9 A0A8I3MTP2 A0A8I3MW51 A0A8I3MYY3 A0A8I3N2D1 A0A8I3N2L9 A0A8I3NCL9 A0A8I3NJM7 A0A8I3NXH1 A0A8I3P2J3 A0A8I3P5C0 A0A8I3P8N1 A0A8I3PRW1 A0A8I3PU35 A0A8I3PV37 A0A8I3PXU4 A0A8I3QDM5 A0A8I3RP60 A0A8I3RSX6 A0A8I3RXZ4 A3RF36 P24463 Q0X0E5	AADAC AHR AHRR ALDH3 ALDH3A1 AOC2 AOC3 ARNT ARNT2 BPHL C5BR CBR3 CES2 CES5A CMBL CYB5B CYB5R3 CYP2B6 CYP3A12 DIA1 EPHX1 LOC119868939 LOC119875773 LOC119876349 MTARC1 NQO2	Canis familiaris (dog)
Assembly and cell surface presentation of NMDA receptors	Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Glutamate receptor Glutamate receptor Glutamate receptor Glutamate receptor	A0A8I3NNK2 A0A8I3NRD6 A0A8I3P9B8 A0A8I3RRH4 Q5R1P0 Q5R1P3	GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRIN3A NMDAR1	Canis familiaris (dog)
SHC-mediated cascade:FGFR2	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Uncharacterized protein small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NUU1 A0A8I3NV07 A0A8I3NYK3 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0	FGF1 FGF10 FGF16 FGF17 FGF18 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2 GRB2 HRAS KGF KRAS NRAS SHC1 SOS1	Canis familiaris (dog)
MET activates RAP1 and RAC1	Adapter molecule crk CRK like proto-oncogene, adaptor protein Dedicator of cytokinesis 7 GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Rap guanine nucleotide exchange factor 1 Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 small monomeric GTPase small monomeric GTPase	A0A8I3NGQ0 A0A8I3NGY1 A0A8I3NH46 A0A8I3NUL4 A0A8I3NXI8 A0A8I3P5F5 A0A8I3PN08 A0A8I3PT69 A0A8I3RSH7 A0A8I3RUF3 P62999 Q867B7	CRK CRKL DOCK7 GAB1 GRB2 HGF MET RAC1 RAP1A RAP1B RAPGEF1	Canis familiaris (dog)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	78 kDa glucose-regulated protein ABC-type antigen peptide transporter Aminopeptidase Beta-2-microglobulin Calnexin Calreticulin GTP-binding protein SAR1b Immunoglobulin C1-set domain-containing protein MHC class I DLA-12 MHC class I DLA-64 MHC class I DLA-88 MHC class Ib Protein SEC13 homolog Protein disulfide-isomerase Protein transport protein SEC23 Protein transport protein Sec31A SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Tapasin	A0A8I3MLY2 A0A8I3N796 A0A8I3N9C4 A0A8I3NCJ5 A0A8I3NCT5 A0A8I3NDA5 A0A8I3NM03 A0A8I3NPS2 A0A8I3NRG2 A0A8I3NSU2 A0A8I3NZH7 A0A8I3P4F9 A0A8I3P4Y2 A0A8I3PXH7 A0A8I3Q7H2 A0A8I3RR85 A0A8I3RUA9 A0A8I3S449 A0A8I3S5M8 A0A8I3SCF9 Q5TJE4	B2M CALR CANX DLA-12 DLA-79 DLA-DOB DLA88 ERAP1 HSPA5 LOC119876190 LOC119876868 PDIA3 SEC13 SEC23A SEC24A SEC24B SEC24C SEC24D SEC31A TAPBP	Canis familiaris (dog)
COPII-mediated vesicle transport	Alpha 1 antitrypsin Ankyrin repeat domain 28 Bet1 golgi vesicular membrane trafficking protein Casein kinase I isoform delta Coagulation factor V Cornichon family AMPA receptor auxiliary protein 1 Cornichon family AMPA receptor auxiliary protein 3 Dipeptidyl peptidase 1 EF-hand domain-containing protein EGF-like domain-containing protein Folate receptor alpha GTP-binding protein SAR1b Gamma-soluble NSF attachment protein General vesicular transport factor p115 Glutamate receptor Golgi SNAP receptor complex member 2 Lectin, mannose binding 1 like Lectin, mannose binding 1 Lectin, mannose binding 2 like MAC-inhibitory protein NSF attachment protein alpha NSF attachment protein beta Prolactin regulatory element-binding protein Protein SEC13 homolog Protein cornichon homolog 2 Protein phosphatase 6 regulatory subunit 1 Protein phosphatase 6 regulatory subunit 3 Protein transport protein SEC23 Protein transport protein Sec31A Protein transport protein sec16 Protein transport protein sec16 Ras-related protein Rab-1A SEC22 homolog A, vesicle trafficking protein SEC22 homolog B, vesicle trafficking protein SEC22 homolog C, vesicle trafficking protein SEC23 interacting protein SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Sec1 family domain containing 1 Serine/threonine-protein phosphatase Syntaxin 17 Syntaxin 5 TBC1 domain family member 20 Trafficking from ER to golgi regulator Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 2 Trafficking protein particle complex subunit 6A Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 9 Trafficking protein particle complex subunit Trafficking protein particle complex subunit Trafficking protein particle complex subunit Transmembrane emp24 domain-containing protein 10 Transmembrane p24 trafficking protein 2 Uncharacterized protein Uncharacterized protein Uncharacterized protein Vesicle-fusing ATPase Vesicular integral-membrane protein VIP36 YKT6 v-SNARE homolog cathepsin X small monomeric GTPase	A0A8I3MAV2 A0A8I3MJ74 A0A8I3MLH1 A0A8I3MLQ0 A0A8I3MT73 A0A8I3MT80 A0A8I3MUS5 A0A8I3MUT1 A0A8I3MY57 A0A8I3MYK4 A0A8I3MZY0 A0A8I3N2I9 A0A8I3N5A8 A0A8I3N5C1 A0A8I3N796 A0A8I3N7P4 A0A8I3N9C4 A0A8I3N9V0 A0A8I3NBA1 A0A8I3NCZ9 A0A8I3NFJ9 A0A8I3NKE3 A0A8I3NPG4 A0A8I3NPS2 A0A8I3NRF0 A0A8I3NT46 A0A8I3NX57 A0A8I3NYM5 A0A8I3NZH7 A0A8I3NZS8 A0A8I3P0W8 A0A8I3P4I1 A0A8I3PAS9 A0A8I3PEN5 A0A8I3PNK8 A0A8I3PQR9 A0A8I3PTJ0 A0A8I3PTW0 A0A8I3PU34 A0A8I3PV59 A0A8I3PVF9 A0A8I3Q314 A0A8I3Q3Y7 A0A8I3Q4E7 A0A8I3Q5G1 A0A8I3Q7H2 A0A8I3QC45 A0A8I3QS42 A0A8I3RR85 A0A8I3RRF7 A0A8I3RSX1 A0A8I3RU45 A0A8I3RUA0 A0A8I3RVH6 A0A8I3RWZ7 A0A8I3RZB2 A0A8I3S3N8 A0A8I3S444 A0A8I3S449 A0A8I3S5V2 A0A8I3SCF9 A1ILJ0 E2QV03 P49256 P62822	ANKRD28 AREG BET1 CD59 CNIH1 CNIH2 CNIH3 CSNK1D CTSC CTSZ F5 GOLGA2 GORASP1 GOSR2 GRIA1 LMAN1 LMAN1L LMAN2 LMAN2L LOC119876190 LOC609612 MCFD2 NAPA NAPB NAPG NSF PPP6C PPP6R1 PPP6R3 PREB RAB1 RAB1A SCFD1 SEC13 SEC16A SEC16B SEC22A SEC22C SEC23A SEC23IP SEC24A SEC24B SEC24C SEC24D SEC31A SERPINA1 STX17 STX5 TBC1D20 TFG TGFA TMED10 TMED2 TRAPPC1 TRAPPC10 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9 USO1 YKT6	Canis familiaris (dog)
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase EF-hand domain-containing protein Inositol polyphosphate-5-phosphatase J Inositol-tetrakisphosphate 1-kinase Kinase Kinase Kinase Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phospholipase C delta 4 Phospholipase C zeta 1 Uncharacterized protein phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase	A0A8I3MH68 A0A8I3MSQ7 A0A8I3MYA9 A0A8I3N810 A0A8I3NFE2 A0A8I3NWQ5 A0A8I3NY96 A0A8I3NZG2 A0A8I3PAP4 A0A8I3PAT0 A0A8I3PB87 A0A8I3PC05 A0A8I3PFD9 A0A8I3PLP7 A0A8I3PN52 A0A8I3PQK7 A0A8I3Q2Q7 A0A8I3Q4W3 A0A8I3Q7I7 A0A8I3Q9F2 A0A8I3QSE4 A0A8I3S2X3 A0A8I3S6D4 A0A8I3S7X1 A0A8I3SCI7 P60483	CALM2 INPP5B INPP5D INPP5J INPPL1 ITPK1 ITPKA ITPKB ITPKC MMAC1 OCRL PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCH1 PLCH2 PLCZ1 PLD4 PTEN SHIP2 SYNJ1	Canis familiaris (dog)
Insulin receptor signalling cascade	Growth factor receptor bound protein 10 Growth factor receptor bound protein 2 Insulin SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A8I3NBK6 A0A8I3NUU1 A0A8I3PT69 A0A8I3PWD4 A0A8I3S3D9 P01321	GRB10 GRB2 INS INSR SHC1 SOS1	Canis familiaris (dog)
Signaling by ROBO receptors	Glypican-1 Slit guidance ligand 2 Slit guidance ligand 3	A0A8I3MRE2 A0A8I3NQC4 A0A8I3Q4U0	GPC1 SLIT2 SLIT3	Canis familiaris (dog)
Tie2 Signaling	Angiopoietin 4 Angiopoietin-1 Angiopoietin-2 Docking protein 2 GTPase HRas GTPase NRas Growth factor receptor bound protein 14 Growth factor receptor bound protein 2 Growth factor receptor bound protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase small monomeric GTPase	A0A5F4C2B1 A0A8I3N971 A0A8I3NC50 A0A8I3NID0 A0A8I3NM36 A0A8I3NUU1 A0A8I3NZA4 A0A8I3PMT9 A0A8I3PSP7 A0A8I3PT69 A0A8I3PWT3 A0A8I3PZB5 A0A8I3Q1A9 A0A8I3Q1I3 A0A8I3S0B4 A0A8I3S3D9 A0A8I3S3N2 A0A8J8	ANGPT1 ANGPT2 ANGPT4 DOK2 GRB14 GRB2 GRB7 HRAS KRAS NRAS PIK3CA PIK3CB PIK3R1 PIK3R2 PTPN11 SHC1 SOS1 TEK	Canis familiaris (dog)
APAP ADME	ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ATP binding cassette subfamily C member 4 ATP binding cassette subfamily C member 5 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome P450 2E1 Cytosolic non-specific dipeptidase Gamma-glutamyltransferase 6 Glutathione S-transferase Glutathione S-transferase Glutathione hydrolase Glutathione hydrolase Glutathione transferase Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 N-acyl-aliphatic-L-amino acid amidohydrolase Sulfotransferase 1A1 Sulfotransferase Sulfotransferase glucuronosyltransferase glucuronosyltransferase glucuronosyltransferase	A0A8I3MEU4 A0A8I3MEX7 A0A8I3N072 A0A8I3N1I8 A0A8I3N279 A0A8I3N2I7 A0A8I3NBB4 A0A8I3NE83 A0A8I3P300 A0A8I3PHP8 A0A8I3PSW5 A0A8I3PVZ3 A0A8I3QRM6 A0A8I3QUB8 A0A8I3S0X8 A0A8I3S4W3 A0A8I3SCV5 B3RFJ1 B8K1W7 Q29476 Q6UR05 Q9MZY0	ABCC1 ABCC2 ABCC3 ABCC4 ABCC5 ABCG2 ABHD14A Abcc4 Abcg2 CNDP2 CYP2E1 GGT1 GGT6 GGT7 GSTP1 LOC119874463 LOC119876946 MRP1 SULT1A1 SULT1C4 SULT1E1 UGT1A6	Canis familiaris (dog)
Keratinization	4Fe-4S ferredoxin-type domain-containing protein Desmocollin 1 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein 4 Desmoglein-3 Desmoplakin IF rod domain-containing protein Junction plakoglobin Keratin 12 Keratin 18 Keratin 23 Keratin 24 Keratin 26 Keratin 28 Keratin 32 Keratin 33B Keratin 35 Keratin 36 Keratin 39 Keratin 3 Keratin 40 Keratin 72 Keratin 73 Keratin 74 Keratin 75 Keratin 76 Keratin 77 Keratin 78 Keratin 80 Keratin 82 Keratin 84 Keratin 85 Keratin 9 Keratin associated protein 8-1 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 19 Keratin, type I cytoskeletal 20 Keratin, type I cytoskeletal 25 Keratin, type I cytoskeletal 27 Keratin, type II cytoskeletal 8 Keratin-associated protein 12-1-like Keratin-associated protein 9-3-like Keratin-associated protein Keratin-associated protein Keratin-associated protein Keratin-associated protein Plakophilin 1 Plakophilin 2 Plakophilin 3 Plakophilin 4 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A5F4CC19 A0A5F4CZ72 A0A8I3MUF8 A0A8I3MVK7 A0A8I3N105 A0A8I3N1J2 A0A8I3N5G6 A0A8I3NBY4 A0A8I3NCT2 A0A8I3NDC0 A0A8I3NEH7 A0A8I3NF36 A0A8I3NF93 A0A8I3NHU5 A0A8I3NIB1 A0A8I3NJG7 A0A8I3NJK2 A0A8I3NKA1 A0A8I3NKS4 A0A8I3NL10 A0A8I3NL87 A0A8I3NMX6 A0A8I3NNI9 A0A8I3NNW0 A0A8I3NPY5 A0A8I3NQB8 A0A8I3NQV4 A0A8I3NQY7 A0A8I3NS58 A0A8I3NSM8 A0A8I3NVV6 A0A8I3NXE8 A0A8I3NYA0 A0A8I3NZ03 A0A8I3P212 A0A8I3P7T0 A0A8I3P9A1 A0A8I3PD35 A0A8I3PD89 A0A8I3PEZ2 A0A8I3PG96 A0A8I3PJ84 A0A8I3PK78 A0A8I3PMV1 A0A8I3PPU4 A0A8I3PTF9 A0A8I3PUR6 A0A8I3PWA5 A0A8I3PWP6 A0A8I3PXA2 A0A8I3PYF6 A0A8I3Q1A4 A0A8I3Q1G9 A0A8I3Q2T7 A0A8I3QMH2 A0A8I3RW47 A0A8I3RXM1 A0A8I3RY38 A0A8I3RZQ2 A0A8I3S024 A0A8I3S0K7 A0A8I3S5Q3 A0A8I3S7M3 A0A8I3S850 A0A8I3S8A6 Q6EIZ0 Q7YRU7	DSC1 DSC3 DSG1 DSG2 DSG3 DSG4 DSP JUP KER10 KRT10 KRT12 KRT15 KRT18 KRT20 KRT23 KRT24 KRT25 KRT26 KRT27 KRT28 KRT3 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT41 KRT72 KRT73 KRT74 KRT75 KRT76 KRT77 KRT78 KRT80 KRT81 KRT82 KRT83 KRT84 KRT85 KRT9 KRTAP11-1 KRTAP24-1 KRTAP3-1 KRTAP8-1 LOC100685322 LOC100685403 LOC100686265 LOC100686358 LOC102151268 LOC102151404 LOC102151604 LOC102151831 LOC102157302 LOC119873184 LOC610887 PKP1 PKP2 PKP3 PKP4	Canis familiaris (dog)
O-glycosylation of TSR domain-containing proteins	A disintegrin and metalloproteinase with thrombospondin motifs 4 ADAM metallopeptidase with thrombospondin type 1 motif 10 ADAM metallopeptidase with thrombospondin type 1 motif 12 ADAM metallopeptidase with thrombospondin type 1 motif 13 ADAM metallopeptidase with thrombospondin type 1 motif 14 ADAM metallopeptidase with thrombospondin type 1 motif 16 ADAM metallopeptidase with thrombospondin type 1 motif 17 ADAM metallopeptidase with thrombospondin type 1 motif 18 ADAM metallopeptidase with thrombospondin type 1 motif 19 ADAM metallopeptidase with thrombospondin type 1 motif 1 ADAM metallopeptidase with thrombospondin type 1 motif 20 ADAM metallopeptidase with thrombospondin type 1 motif 2 ADAM metallopeptidase with thrombospondin type 1 motif 3 ADAM metallopeptidase with thrombospondin type 1 motif 5 ADAM metallopeptidase with thrombospondin type 1 motif 6 ADAM metallopeptidase with thrombospondin type 1 motif 8 ADAM metallopeptidase with thrombospondin type 1 motif 9 ADAMTS like 1 ADAMTS like 2 ADAMTS like 4 Beta 3-glucosyltransferase Complement factor properdin GDP-fucose protein O-fucosyltransferase 2 NTR domain-containing protein SCO-spondin Semaphorin 5A Semaphorin 5B Somatomedin B and thrombospondin type 1 domain containing Spondin-1 Thrombospondin 1 Thrombospondin 2 Thrombospondin type 1 domain containing 7A Thrombospondin type 1 domain containing 7B Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A4D6CAB5 A0A8I3MD18 A0A8I3MIA8 A0A8I3MQ02 A0A8I3MRT7 A0A8I3MXQ6 A0A8I3MZ18 A0A8I3MZD5 A0A8I3N140 A0A8I3N1D3 A0A8I3N2T5 A0A8I3NA49 A0A8I3NAX6 A0A8I3NB75 A0A8I3NE19 A0A8I3NGS7 A0A8I3NK12 A0A8I3NKG0 A0A8I3NM21 A0A8I3NS78 A0A8I3P088 A0A8I3P1X0 A0A8I3P533 A0A8I3PA53 A0A8I3PBE9 A0A8I3PG52 A0A8I3PJ96 A0A8I3PJW2 A0A8I3PNR9 A0A8I3PPJ4 A0A8I3PPU8 A0A8I3PQZ5 A0A8I3PUQ0 A0A8I3Q3A2 A0A8I3Q4T9 A0A8I3Q9Y4 A0A8I3RTV1 A0A8I3S8L6	ADAMTS1 ADAMTS10 ADAMTS12 ADAMTS13 ADAMTS14 ADAMTS15 ADAMTS16 ADAMTS17 ADAMTS18 ADAMTS19 ADAMTS2 ADAMTS20 ADAMTS3 ADAMTS4 ADAMTS5 ADAMTS6 ADAMTS7 ADAMTS8 ADAMTS9 ADAMTSL1 ADAMTSL2 ADAMTSL4 ADAMTSL5 B3GLCT CFP POFUT2 SBSPON SEMA5A SEMA5B SH3GL3 SPON1 SPON2 SSPO THBS1 THBS2 THSD1 THSD7A THSD7B	Canis familiaris (dog)
PI3K Cascade	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Klotho beta Klotho Multifunctional fusion protein Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Toll-like receptor 9 Toll-like receptor 9 Tyrosine-protein phosphatase non-receptor type Uncharacterized protein non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3MWD3 A0A8I3N971 A0A8I3N9M7 A0A8I3NHA2 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NS74 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NVV1 A0A8I3NVW9 A0A8I3NXI8 A0A8I3NYK3 A0A8I3P4L9 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PK39 A0A8I3PMT9 A0A8I3PT69 A0A8I3PWT3 A0A8I3Q7B4 A0A8I3QFN1 A0A8I3RTN7 A0A8I3S0I1 A0A8I3S3N2 A0A8I3S8G3 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0 Q5I2M8	FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 GAB1 GAB2 GRB2 IRS1 IRS2 KGF KL KLB PIK3C3 PIK3CA PIK3CB PIK3R1 PIK3R2 PIK3R4 PTPN11 TLR9	Canis familiaris (dog)
CD22 mediated BCR regulation	B-cell antigen receptor complex-associated protein alpha chain B-cell receptor CD22 CD79a molecule CD79b molecule Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A8I3MIL9 A0A8I3MUW4 A0A8I3NVL7 A0A8I3NWR3 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P501 A0A8I3P6V2 A0A8I3P941 A0A8I3PD67 A0A8I3PDA6 A0A8I3PDU9 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUN0 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWC6 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S6H5 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 P0CAN6	CD79A CD79B IGHM LYN MAG PTPN6	Canis familiaris (dog)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho Multifunctional fusion protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3PJY6 A0A8I3SAY5 A0A8I3SCI7 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 KL PLCG1	Canis familiaris (dog)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	A0A8I3NI15 A0A8I3NVW9 A0A8I3PAR4 A0A8I3RQ77 A0A8I3S0I1 P33712	IGF1 IGF1R IGF2 IGFIA IRS1 IRS2 IRS4	Canis familiaris (dog)
Cargo concentration in the ER	Alpha 1 antitrypsin Coagulation factor V Cornichon family AMPA receptor auxiliary protein 1 Cornichon family AMPA receptor auxiliary protein 3 Dipeptidyl peptidase 1 EF-hand domain-containing protein EGF-like domain-containing protein Folate receptor alpha GTP-binding protein SAR1b Glutamate receptor Golgi SNAP receptor complex member 2 Lectin, mannose binding 1 like Lectin, mannose binding 1 Lectin, mannose binding 2 like MAC-inhibitory protein Prolactin regulatory element-binding protein Protein cornichon homolog 2 Protein transport protein SEC23 SEC22 homolog B, vesicle trafficking protein SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Syntaxin 5 Transmembrane emp24 domain-containing protein 10 Transmembrane p24 trafficking protein 2 Uncharacterized protein Uncharacterized protein Vesicular integral-membrane protein VIP36 cathepsin X	A0A8I3MAV2 A0A8I3MLH1 A0A8I3MT80 A0A8I3MUT1 A0A8I3MY57 A0A8I3MYK4 A0A8I3N2I9 A0A8I3N5W4 A0A8I3N796 A0A8I3N9V0 A0A8I3NPS2 A0A8I3NRF0 A0A8I3NT46 A0A8I3NYM5 A0A8I3NZH7 A0A8I3P0W8 A0A8I3P4I1 A0A8I3PEN5 A0A8I3PQR9 A0A8I3PTW0 A0A8I3Q314 A0A8I3Q3Y7 A0A8I3Q7H2 A0A8I3RR85 A0A8I3RU45 A0A8I3RWZ7 A0A8I3S5V2 A0A8I3SCF9 A1ILJ0 P49256	AREG CD59 CNIH1 CNIH2 CNIH3 CTSC CTSZ F5 GOSR2 GRIA1 LMAN1 LMAN1L LMAN2 LMAN2L LOC119876190 LOC609612 MCFD2 MIA2 PREB SEC23A SEC24A SEC24B SEC24C SEC24D SERPINA1 STX5 TGFA TMED10 TMED2	Canis familiaris (dog)
Class B/2 (Secretin family receptors)	Adhesion G protein-coupled receptor E1 Adhesion G protein-coupled receptor E3 Adhesion G protein-coupled receptor E5 Corticoliberin Corticotropin releasing hormone receptor 2 Corticotropin-releasing factor receptor 1 Corticotropin-releasing factor-binding protein Parathyroid hormone 2 receptor Parathyroid hormone-related protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parathyroid hormone Sushi domain-containing protein Tuberoinfundibular peptide of 39 residues Uncharacterized protein Uncharacterized protein Urocortin	A0A8I3MZB5 A0A8I3P6W0 A0A8I3P7R9 A0A8I3PCJ2 A0A8I3PCP1 A0A8I3PHA9 A0A8I3PPK6 A0A8I3PPW2 A0A8I3RQ73 A0A8I3RSJ3 A0A8I3RVU2 A0A8I3RXL4 P52211 P52212 Q2Q423 Q9TU31	ADGRE1 ADGRE3 ADGRE5 CD55 CRH CRHBP CRHR1 CRHR2 LOC484897 PTH PTH1 PTH1R PTH2 PTH2R PTHLH PTHR1 UCN UCN3	Canis familiaris (dog)
GABA synthesis, release, reuptake and degradation	Complexin-1 DnaJ homolog subfamily C member 5 Glutamate decarboxylase 1 Glutamate decarboxylase 2 Heat shock cognate 71 kDa protein Multifunctional fusion protein Ras-related protein Rab-3 Regulating synaptic membrane exocytosis 1 Synaptotagmin Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Vesicular inhibitory amino acid transporter	A0A8I3ME77 A0A8I3MLF8 A0A8I3MQ89 A0A8I3N2E5 A0A8I3N5Z9 A0A8I3NNW3 A0A8I3P737 A0A8I3PDP4 A0A8I3PNE3 A0A8I3Q823 A0A8I3S6J8 A0PA85 Q4PRC2	CPLX1 DNAJC5 GAD1 GAD2 GAD65 GAD67 LOC607182 RAB3A RIMS1 SLC32A1 SNAP25 STX1A STXBP1 SYT1 VAMP2	Canis familiaris (dog)
Inactivation, recovery and regulation of the phototransduction cascade	Calmodulin-lysine N-methyltransferase Cyclic nucleotide gated channel subunit beta 1 EF-hand domain-containing protein G protein-coupled receptor kinase G protein-coupled receptor kinase G protein-coupled receptor kinase Glycylpeptide N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase Guanine nucleotide-binding protein G(t) subunit alpha-1 Guanine nucleotide-binding protein subunit beta-5 Guanylate cyclase activator 1C Guanylate cyclase Guanylate cyclase Guanylyl cyclase-activating protein 1 Methionine aminopeptidase 2 Methionine aminopeptidase Phosphodiesterase Recoverin Regulator of G protein signaling 9 binding protein Regulator of G-protein signaling 9 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta S-arrestin Serine/threonine-protein phosphatase with EF-hands cGMP-gated cation channel alpha-1	A0A8I3MKZ0 A0A8I3MLZ0 A0A8I3MQ38 A0A8I3MR23 A0A8I3MSQ7 A0A8I3NB80 A0A8I3NDY5 A0A8I3NJ95 A0A8I3NUA6 A0A8I3P9Q1 A0A8I3PF51 A0A8I3PM46 A0A8I3PRB5 A0A8I3PV05 A0A8I3PV39 A0A8I3PWQ2 A0A8I3Q053 A0A8I3Q0S6 A0A8I3Q144 A0A8I3QE57 A0A8I3S5I9 A0A8I3S6V0 P33726 P54827 Q28263 Q28300 Q8MIH6	CALM2 CAMKMT CNGA1 CNGB1 GNAT1 GNB5 GRK1 GRK4 GRK7 GUCA1A GUCA1C GUCY2D GUCY2F METAP1 METAP2 NMT1 NMT2 PDBS PDE6A PDE6B PDE6G PDEA PDEB PDEG PPEF1 RCV1 RCVRN RGS9 RGS9BP RHO SAG	Canis familiaris (dog)

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