GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **126 - 150** of **268** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	A0A8I3NI15 A0A8I3NVW9 A0A8I3PAR4 A0A8I3RQ77 A0A8I3S0I1 P33712	IGF1 IGF1R IGF2 IGFIA IRS1 IRS2 IRS4	Canis familiaris (dog)
Cargo concentration in the ER	Alpha 1 antitrypsin Coagulation factor V Cornichon family AMPA receptor auxiliary protein 1 Cornichon family AMPA receptor auxiliary protein 3 Dipeptidyl peptidase 1 EF-hand domain-containing protein EGF-like domain-containing protein Folate receptor alpha GTP-binding protein SAR1b Glutamate receptor Golgi SNAP receptor complex member 2 Lectin, mannose binding 1 like Lectin, mannose binding 1 Lectin, mannose binding 2 like MAC-inhibitory protein Prolactin regulatory element-binding protein Protein cornichon homolog 2 Protein transport protein SEC23 SEC22 homolog B, vesicle trafficking protein SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component Syntaxin 5 Transmembrane emp24 domain-containing protein 10 Transmembrane p24 trafficking protein 2 Uncharacterized protein Uncharacterized protein Vesicular integral-membrane protein VIP36 cathepsin X	A0A8I3MAV2 A0A8I3MLH1 A0A8I3MT80 A0A8I3MUT1 A0A8I3MY57 A0A8I3MYK4 A0A8I3N2I9 A0A8I3N5W4 A0A8I3N796 A0A8I3N9V0 A0A8I3NPS2 A0A8I3NRF0 A0A8I3NT46 A0A8I3NYM5 A0A8I3NZH7 A0A8I3P0W8 A0A8I3P4I1 A0A8I3PEN5 A0A8I3PQR9 A0A8I3PTW0 A0A8I3Q314 A0A8I3Q3Y7 A0A8I3Q7H2 A0A8I3RR85 A0A8I3RU45 A0A8I3RWZ7 A0A8I3S5V2 A0A8I3SCF9 A1ILJ0 P49256	AREG CD59 CNIH1 CNIH2 CNIH3 CTSC CTSZ F5 GOSR2 GRIA1 LMAN1 LMAN1L LMAN2 LMAN2L LOC119876190 LOC609612 MCFD2 MIA2 PREB SEC23A SEC24A SEC24B SEC24C SEC24D SERPINA1 STX5 TGFA TMED10 TMED2	Canis familiaris (dog)
Class B/2 (Secretin family receptors)	Adhesion G protein-coupled receptor E1 Adhesion G protein-coupled receptor E3 Adhesion G protein-coupled receptor E5 Corticoliberin Corticotropin releasing hormone receptor 2 Corticotropin-releasing factor receptor 1 Corticotropin-releasing factor-binding protein Parathyroid hormone 2 receptor Parathyroid hormone-related protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parathyroid hormone Sushi domain-containing protein Tuberoinfundibular peptide of 39 residues Uncharacterized protein Uncharacterized protein Urocortin	A0A8I3MZB5 A0A8I3P6W0 A0A8I3P7R9 A0A8I3PCJ2 A0A8I3PCP1 A0A8I3PHA9 A0A8I3PPK6 A0A8I3PPW2 A0A8I3RQ73 A0A8I3RSJ3 A0A8I3RVU2 A0A8I3RXL4 P52211 P52212 Q2Q423 Q9TU31	ADGRE1 ADGRE3 ADGRE5 CD55 CRH CRHBP CRHR1 CRHR2 LOC484897 PTH PTH1 PTH1R PTH2 PTH2R PTHLH PTHR1 UCN UCN3	Canis familiaris (dog)
GABA synthesis, release, reuptake and degradation	Complexin-1 DnaJ homolog subfamily C member 5 Glutamate decarboxylase 1 Glutamate decarboxylase 2 Heat shock cognate 71 kDa protein Multifunctional fusion protein Ras-related protein Rab-3 Regulating synaptic membrane exocytosis 1 Synaptotagmin Syntaxin-1A Syntaxin-binding protein 1 Vesicle-associated membrane protein 2 Vesicular inhibitory amino acid transporter	A0A8I3ME77 A0A8I3MLF8 A0A8I3MQ89 A0A8I3N2E5 A0A8I3N5Z9 A0A8I3NNW3 A0A8I3P737 A0A8I3PDP4 A0A8I3PNE3 A0A8I3Q823 A0A8I3S6J8 A0PA85 Q4PRC2	CPLX1 DNAJC5 GAD1 GAD2 GAD65 GAD67 LOC607182 RAB3A RIMS1 SLC32A1 SNAP25 STX1A STXBP1 SYT1 VAMP2	Canis familiaris (dog)
Inactivation, recovery and regulation of the phototransduction cascade	Calmodulin-lysine N-methyltransferase Cyclic nucleotide gated channel subunit beta 1 EF-hand domain-containing protein G protein-coupled receptor kinase G protein-coupled receptor kinase G protein-coupled receptor kinase Glycylpeptide N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase Guanine nucleotide-binding protein G(t) subunit alpha-1 Guanine nucleotide-binding protein subunit beta-5 Guanylate cyclase activator 1C Guanylate cyclase Guanylate cyclase Guanylyl cyclase-activating protein 1 Methionine aminopeptidase 2 Methionine aminopeptidase Phosphodiesterase Recoverin Regulator of G protein signaling 9 binding protein Regulator of G-protein signaling 9 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta S-arrestin Serine/threonine-protein phosphatase with EF-hands cGMP-gated cation channel alpha-1	A0A8I3MKZ0 A0A8I3MLZ0 A0A8I3MQ38 A0A8I3MR23 A0A8I3MSQ7 A0A8I3NB80 A0A8I3NDY5 A0A8I3NJ95 A0A8I3NUA6 A0A8I3P9Q1 A0A8I3PF51 A0A8I3PM46 A0A8I3PRB5 A0A8I3PV05 A0A8I3PV39 A0A8I3PWQ2 A0A8I3Q053 A0A8I3Q0S6 A0A8I3Q144 A0A8I3QE57 A0A8I3S5I9 A0A8I3S6V0 P33726 P54827 Q28263 Q28300 Q8MIH6	CALM2 CAMKMT CNGA1 CNGB1 GNAT1 GNB5 GRK1 GRK4 GRK7 GUCA1A GUCA1C GUCY2D GUCY2F METAP1 METAP2 NMT1 NMT2 PDBS PDE6A PDE6B PDE6G PDEA PDEB PDEG PPEF1 RCV1 RCVRN RGS9 RGS9BP RHO SAG	Canis familiaris (dog)
FRS-mediated FGFR2 signaling	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor substrate 3 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Multifunctional fusion protein SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type Uncharacterized protein small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MIK8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NM39 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3P4L9 A0A8I3P6D2 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 J9P8K0 P79150 Q20FD0	FGF1 FGF10 FGF16 FGF17 FGF18 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR2 FRS2 FRS3 GRB2 HRAS KGF KRAS NRAS PTPN11 SOS1	Canis familiaris (dog)
Regulation of TNFR1 signaling	Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing protein 3 CAP-Gly domain containing linker protein 3 Caspase 8 Caspase 9 E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase XIAP IkappaB kinase Inhibitor of nuclear factor kappa B kinase subunit epsilon Inhibitor of nuclear factor kappa-B kinase subunit alpha MAP kinase-activating death domain protein NF-kappa-B essential modulator Optineurin RBR-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Serine/threonine-protein kinase Signal peptide peptidase like 2A Signal peptide peptidase like 2B Small ribosomal subunit protein RACK1 Spermatogenesis associated 2 TANK binding kinase 1 TNF receptor-associated factor TNFR-Cys domain-containing protein Tax1 binding protein 1 Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin B Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin conjugating enzyme E2 D3 Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A8I3MA34 A0A8I3MAP5 A0A8I3MDM0 A0A8I3MJ82 A0A8I3MKR0 A0A8I3MLM6 A0A8I3MMN5 A0A8I3MQC7 A0A8I3MSL4 A0A8I3MYA4 A0A8I3N1V1 A0A8I3N4F2 A0A8I3NEJ2 A0A8I3NFB9 A0A8I3NK16 A0A8I3NLZ9 A0A8I3NP69 A0A8I3NS04 A0A8I3P2P4 A0A8I3P499 A0A8I3PLX1 A0A8I3PRU0 A0A8I3PS24 A0A8I3PT83 A0A8I3PW29 A0A8I3PWL6 A0A8I3PZS6 A0A8I3Q155 A0A8I3Q3L1 A0A8I3QYD0 A0A8I3RSQ2 A0A8I3RUY7 A0A8I3RZA9 A0A8I3RZI9 A0A8I3S2L7 A0A8I3S5W5 A0A8I3S792 A0A8I3S794 A1E2V0 P51742 P63050 Q38IV1 Q38JA9	BIRC2 BIRC3 BIRC4 CASP8 CASP9 CHUK CLIP3 CYLD IKBKB IKBKE IKBKG IRF9 MADD MIB2 OPTN OTUD1 OTUD7B RACK1 RBCK1 RIPK1 RPS27A SPATA2 SPPL2A SPPL2B STUB1 TAX1BP1 TBK1 TNF TNFA TNFAIP3 TNFRSF1A TNFSF2 TRADD TRAF2 UBA52 UBB UBC UBCEP2 UBE2D1 UBE2D2 UBE2D3 UBE2L3 ULK1 USP2 USP21 USP4 XIAP	Canis familiaris (dog)
Costimulation by the CD28 family	B and T lymphocyte associated Growth factor receptor bound protein 2 Ig-like domain-containing protein Inducible T-cell costimulator Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 TNF receptor superfamily member 14 Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3N971 A0A8I3P405 A0A8I3P519 A0A8I3P6Z0 A0A8I3PMT9 A0A8I3PT69 A0A8I3PWC6 A0A8I3Q857 A0A8I3S3N2 Q7YR73	AILIM BTLA GRB2 ICOS ICOSLG LOC100856339 PIK3CA PIK3R1 PIK3R2 PTPN11 PTPN6 TNFRSF14	Canis familiaris (dog)
TNFs bind their physiological receptors	CD27 molecule CD70 molecule EDAR associated via death domain Ectodysplasin A receptor Ectodysplasin A LIGHT Lymphotoxin-alpha Migration and invasion inhibitory protein TNF family profile domain-containing protein TNF receptor superfamily member 14 TNF receptor superfamily member 17 TNF receptor superfamily member 18 TNF receptor superfamily member 1B TNF receptor superfamily member 6b TNF receptor superfamily member 9 TNF superfamily member 13 TNF superfamily member 13b TNF superfamily member 18 TNF superfamily member 4 TNF superfamily member 8 TNFR-Cys domain-containing protein Tumor necrosis factor ligand superfamily member Tumor necrosis factor receptor superfamily member 11B Uncharacterized protein Uncharacterized protein	A0A0U5JAK9 A0A8I3MEA7 A0A8I3MKG7 A0A8I3MM10 A0A8I3MPQ0 A0A8I3N568 A0A8I3NB07 A0A8I3NFC1 A0A8I3NGJ3 A0A8I3NJU2 A0A8I3NZX5 A0A8I3P405 A0A8I3PKB9 A0A8I3PLK9 A0A8I3PMM9 A0A8I3Q3L1 A0A8I3Q7M4 A0A8I3QDG0 A0A8I3S9F2 E2R8I1 E2RP79 J9JHM5 J9P753 Q58P77 Q5WR07	CD27 CD70 EDA EDAR EDARADD LTA MIIP TNFB TNFRSF11B TNFRSF13B TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF1A TNFRSF1B TNFRSF4 TNFRSF6B TNFRSF9 TNFSF1 TNFSF11 TNFSF13 TNFSF13B TNFSF14 TNFSF18 TNFSF4 TNFSF8 TNLG1D TNLG2A TNLG2B TNLG3A TNLG7A	Canis familiaris (dog)
Galactose catabolism	Galactokinase 1 Galactokinase Galactose-1-phosphate uridylyltransferase UDP-glucose 4-epimerase	A0A8I3P3X5 A0A8I3PNL4 A0A8I3PT77 Q9GKK4	GALE GALK1 GALT H3-3B	Canis familiaris (dog)	G93924TT
Activation of the phototransduction cascade	Cyclic nucleotide gated channel subunit beta 1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(t) subunit alpha-1 Phosphodiesterase Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta cGMP-gated cation channel alpha-1	A0A8I3MLZ0 A0A8I3MQ38 A0A8I3NB80 A0A8I3QE57 P33726 P54827 P62872 P63210 Q28263 Q28300	CNGA1 CNGB1 GNAT1 GNB1 GNGT1 PDBS PDE6A PDE6B PDE6G PDEA PDEB PDEG RHO	Canis familiaris (dog)
MAP2K and MAPK activation	Amyloid beta A4 precursor protein-binding family B member 1-interacting protein Beta-arrestin-1 Beta-arrestin-2 Connector enhancer of kinase suppressor of Ras 1 Connector enhancer of kinase suppressor of Ras 2 Dual specificity mitogen-activated protein kinase kinase 2 Fibronectin GTPase HRas GTPase NRas Integrin beta Integrin subunit alpha 2b Interleukin 17 receptor D Kinase suppressor of ras 1 Kinase suppressor of ras 2 Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Mitogen-activated protein kinase Mitogen-activated protein kinase Phosphatidylethanolamine-binding protein 1 Phosphatidylethanolamine-binding protein 1 RAF proto-oncogene serine/threonine-protein kinase Ragulator complex protein LAMTOR3 Talin 1 Tyrosine-protein kinase Tyrosine-protein kinase Vinculin WD repeat domain-containing protein 83 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase small monomeric GTPase small monomeric GTPase small monomeric GTPase von Willebrand factor von Willebrand factor	A0A8I3N6K0 A0A8I3N737 A0A8I3N7S1 A0A8I3NR25 A0A8I3NUL4 A0A8I3P1J7 A0A8I3P2I8 A0A8I3P4Z0 A0A8I3PDX9 A0A8I3PED8 A0A8I3PMU9 A0A8I3PP92 A0A8I3PSP7 A0A8I3PTA1 A0A8I3PZA0 A0A8I3PZB5 A0A8I3PZP0 A0A8I3Q1I3 A0A8I3Q3R4 A0A8I3Q981 A0A8I3RQD0 A0A8I3RUF3 A0A8I3RVR5 A0A8I3RXW5 A0A8I3RZ76 A0A8I3RZF8 A0A8I3S756 A0A8I3SAZ0 A0A8I3SBF9 A0A8I3SCK0 A0A8I3SCX1 Q1HG70 Q28295 Q3YIX4	APBB1IP ARAF ARRB1 ARRB2 BRAF CNKSR1 CNKSR2 CSK F8VWF FN1 HRAS IL17RD ITGA2B ITGB3 KRAS KSR1 KSR2 LAMTOR2 LAMTOR3 MAP2K2 MAPK1 MAPK3 MARK3 MEK2 NRAS PBP PEBP1 RAF1 RAP1A RAP1B SRC TLN1 VCL VWF WDR83	Canis familiaris (dog)
Extracellular matrix organization	Fibronectin	A0A8I3PED8	FN1	Canis familiaris (dog)
The canonical retinoid cycle in rods (twilight vision)	ATP binding cassette subfamily A member 4 Cytochrome P450 family 4 subfamily V member 2 Cytosolic fatty-acid binding proteins domain-containing protein Dehydrogenase/reductase 9 Hydroxysteroid 17-beta dehydrogenase 6 Lecithin retinol acyltransferase Myosin VIIA NADP-retinol dehydrogenase Plasma retinol-binding protein Receptor for retinol uptake STRA6 Retinaldehyde binding protein 1 Retinoid isomerohydrolase Retinol binding protein 3 Retinol dehydrogenase 12 Retinol dehydrogenase 16 Retinol dehydrogenase 5 Rhodopsin Short chain dehydrogenase/reductase family 9C member 7 Transthyretin	A0A8I3MJB9 A0A8I3MRK7 A0A8I3MTG2 A0A8I3N0K5 A0A8I3N0Y3 A0A8I3N2V4 A0A8I3N8N5 A0A8I3NEZ4 A0A8I3NFK0 A0A8I3NXV6 A0A8I3P9M8 A0A8I3PAT8 A0A8I3Q0S8 A0A8I3Q3P2 A0A8I3QE57 A0A8I3QHU9 A0A8I3RVK1 A0A8I3RWP2 A0A8I3S143	ABCA4 CYP4V2 DHRS9 HSD17B6 LRAT MYO7A RBP1 RBP3 RBP4 RDH10 RDH12 RDH16 RDH5 RHO RLBP1 RPE65 SDR9C7 STRA6 TTR	Canis familiaris (dog)
Stimuli-sensing channels	Acid sensing ion channel subunit 1 Acid sensing ion channel subunit 2 Acid sensing ion channel subunit 3 Acid sensing ion channel subunit family member 4 Acid sensing ion channel subunit family member 5 Amiloride-sensitive sodium channel subunit alpha Amiloride-sensitive sodium channel subunit beta Amiloride-sensitive sodium channel subunit gamma Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Anoctamin Aspartate beta-hydroxylase Barttin CLCNK type accessory subunit beta Bestrophin Bestrophin Bestrophin Bestrophin Calcium-activated chloride channel regulator 1 Chloride channel accessory 2 Chloride channel accessory 4 Chloride channel protein 1 Chloride channel protein 2 Chloride channel protein Chloride channel protein Chloride channel protein Chloride channel protein Chloride channel protein Chloride intracellular channel protein E3 ubiquitin-protein ligase EF-hand domain-containing protein HECT-type E3 ubiquitin transferase Osteoclastogenesis associated transmembrane protein 1 Protein tweety homolog Protein tweety homolog Protein tweety homolog RAF proto-oncogene serine/threonine-protein kinase Ryanodine receptor 1 Ryanodine receptor 2 Ryanodine receptor 3 Serine/threonine-protein kinase Sgk1 Serum/glucocorticoid regulated kinase family, member 3 Sodium channel epithelial 1 subunit delta Sodium leak channel, non-selective Solute carrier family 17 member 3 Solute carrier family 9 member B1 Solute carrier family 9 member B2 Solute carrier family 9 member C2 (putative) Sorcin Stomatin like 3 Stomatin Triadin Two pore segment channel 1 Two pore segment channel 2 Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Unc-79 homolog, NALCN channel complex subunit Unc-80 homolog, NALCN channel complex subunit peptidylprolyl isomerase	A0A8I3M9N6 A0A8I3MIG8 A0A8I3MK25 A0A8I3MKE6 A0A8I3MKT6 A0A8I3MMN5 A0A8I3MSQ7 A0A8I3MT21 A0A8I3MUX4 A0A8I3MXS3 A0A8I3N0C5 A0A8I3N0E7 A0A8I3N106 A0A8I3N6S0 A0A8I3N726 A0A8I3NAC3 A0A8I3NFB9 A0A8I3NH80 A0A8I3NHZ8 A0A8I3NKC4 A0A8I3NSX7 A0A8I3NUI9 A0A8I3NXW9 A0A8I3NYL1 A0A8I3P370 A0A8I3P4T9 A0A8I3P560 A0A8I3P659 A0A8I3P6A5 A0A8I3P7M3 A0A8I3P948 A0A8I3PAS7 A0A8I3PCD4 A0A8I3PDN2 A0A8I3PET1 A0A8I3PGN5 A0A8I3PJ01 A0A8I3PJ21 A0A8I3PJD4 A0A8I3PNF9 A0A8I3PP54 A0A8I3PRH5 A0A8I3PSM5 A0A8I3PV66 A0A8I3PY43 A0A8I3PZA0 A0A8I3Q0B9 A0A8I3Q0M9 A0A8I3Q2P4 A0A8I3Q383 A0A8I3Q4Q6 A0A8I3Q679 A0A8I3Q886 A0A8I3Q8P6 A0A8I3Q8R4 A0A8I3QA03 A0A8I3QXX9 A0A8I3QYD0 A0A8I3RQJ2 A0A8I3RSF1 A0A8I3RW06 A0A8I3RY81 A0A8I3RZ58 A0A8I3S651 A0A8I3SA78 P63050 Q9MZT1	ANO1 ANO2 ANO3 ANO4 ANO5 ANO6 ANO7 ANO8 ANO9 ASIC1 ASIC2 ASIC3 ASIC4 ASIC5 ASPH BEST1 BEST2 BEST3 BEST4 BSND CALM2 CLCA1 CLCA2 CLCA4 CLCN1 CLCN2 CLCN4 CLCN5 CLCN6 CLCN7 CLCNK CLCNKA CLIC2 LOC119880472 NALCN NEDD4L OSTM1 RAF1 RPS27A RYR1 RYR2 RYR3 SCNN1A SCNN1B SCNN1D SCNN1G SGK1 SGK3 SLC17A2 SLC9B1 SLC9B2 SLC9C2 SRI STOM STOML3 TPCN1 TPCN2 TRDN TTYH1 TTYH2 TTYH3 UBA52 UBB UBC UBCEP2 UNC79 UNC80 WWP1	Canis familiaris (dog)
Formation of the cornified envelope	Calpain small subunit 1 Calpain-1 catalytic subunit Caspase 14 Corneodesmosin Cystatin A Desmocollin 1 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein 4 Desmoglein-3 Desmoplakin EF-hand domain-containing protein EF-hand domain-containing protein EF-hand domain-containing protein Junction plakoglobin Kallikrein related peptidase 12 Kallikrein related peptidase 13 Kallikrein related peptidase 14 Kazrin, periplakin interacting protein Lipase Lipase Lipase P53 apoptosis effector related to PMP22 Partial AB-hydrolase lipase domain-containing protein Peptidase inhibitor 3 Periplakin Plakophilin 1 Plakophilin 2 Plakophilin 3 Plakophilin 4 Proprotein convertase subtilisin/kexin type 6 Protein-glutamine gamma-glutamyltransferase K SH3 domain-containing protein Serine peptidase inhibitor Kazal type 6 Serine protease 8 Uncharacterized protein furin	A0A8I3MEZ7 A0A8I3MGG5 A0A8I3MMJ6 A0A8I3MP57 A0A8I3MV56 A0A8I3N1T9 A0A8I3N282 A0A8I3NHU5 A0A8I3NIB1 A0A8I3NJG7 A0A8I3NL10 A0A8I3NLL5 A0A8I3NRG5 A0A8I3NVV6 A0A8I3NXI7 A0A8I3NYR0 A0A8I3NZ03 A0A8I3P0I4 A0A8I3P212 A0A8I3PDW6 A0A8I3PMI7 A0A8I3PQU9 A0A8I3PW84 A0A8I3PYD8 A0A8I3Q1A4 A0A8I3Q2T7 A0A8I3Q6Y1 A0A8I3Q7P7 A0A8I3Q910 A0A8I3QKA9 A0A8I3RW47 A0A8I3RY38 A0A8I3RYD5 A0A8I3S0K7 A0A8I3S9F9 D3DMB4 F1PHB6 Q7YRU7	CAPN1 CAPNS1 CASP14 CSTA DSC1 DSC3 DSG1 DSG2 DSG3 DSG4 DSP EVPL FLG FURIN JUP KAZN KLK12 KLK13 KLK14 LIPJ LIPK LIPM LIPN LOC119876865 PCSK6 PERP PI3 PKP1 PKP2 PKP3 PKP4 PPL PRSS8 RPTN SPINK6 TCHH TGM1 cystatin A	Canis familiaris (dog)
Regulation of Glucokinase by Glucokinase Regulatory Protein	Aladin WD repeat nucleoporin BIG2 domain-containing protein Glucokinase regulator Nuclear pore complex protein Nup85 Nuclear pore complex protein Nup93 Nuclear pore complex protein Nup98-Nup96 Nuclear pore complex protein Nucleoporin 133 Nucleoporin 153 Nucleoporin 155 Nucleoporin 160 Nucleoporin 205 Nucleoporin 214 Nucleoporin 37 Nucleoporin 43 Nucleoporin 50 Nucleoporin 54 Nucleoporin 58 Nucleoporin 62 Nucleoporin 88 Nucleoporin NDC1 Nucleoporin NUP188 Nucleoporin NUP35 Nucleoporin NUP42 Nucleoprotein TPR POM121 transmembrane nucleoporin C Phosphotransferase Protein SEC13 homolog Uncharacterized protein	A0A8I3MJ67 A0A8I3MKP8 A0A8I3MMX0 A0A8I3MS44 A0A8I3MW92 A0A8I3MW93 A0A8I3MZ55 A0A8I3N5H9 A0A8I3N8Q5 A0A8I3N975 A0A8I3N9C4 A0A8I3NAH9 A0A8I3NAY7 A0A8I3NDG5 A0A8I3NIY6 A0A8I3NMR5 A0A8I3NQA4 A0A8I3NV53 A0A8I3NZW0 A0A8I3P0U9 A0A8I3P537 A0A8I3P769 A0A8I3PAE6 A0A8I3PBR9 A0A8I3PUC1 A0A8I3Q2U4 A0A8I3S484 A0A8I3S533 A0A8I3S9D7	AAAS GCK GCKR NDC1 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 NUP35 NUP37 NUP42 NUP43 NUP50 NUP54 NUP58 NUP62 NUP85 NUP88 NUP93 NUP98 POM121C RANBP2 SEC13 TPR	Canis familiaris (dog)	G58161NS
Histamine receptors	Histamine H1 receptor Histamine H2 receptor Histamine receptor H3 Histamine receptor H4	A0A8I3MSX9 A0A8I3NPW0 A0A8I3P226 P17124	HRH1 HRH2 HRH3 HRH4	Canis familiaris (dog)
Transport of inorganic cations/anions and amino acids/oligopeptides	Amino acid transporter Amino acid transporter Amino acid transporter Amino acid transporter Amino acid transporter Cystinosin, lysosomal cystine transporter Mitochondrial S-adenosylmethionine carrier protein Vesicular inhibitory amino acid transporter	A0A8I3N947 A0A8I3NY92 A0A8I3P1B2 A0A8I3P4E1 A0A8I3PQ76 A0A8I3Q823 A0A8I3RSG2 Q9N280	CTNS GLAST SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 SLC25A26 SLC32A1	Canis familiaris (dog)
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Arachidonate 5-lipoxygenase-activating protein Arachidonate 5-lipoxygenase Cytochrome P450 4A37 Cytochrome P450 4A39 Cytochrome P450 family 4 subfamily B member 1 Cytochrome P450 family 4 subfamily F member 22 Dipeptidase 3 Dipeptidase Dipeptidase Glutathione hydrolase Leukotriene A(4) hydrolase Leukotriene C4 synthase Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Polyunsaturated fatty acid lipoxygenase ALOX15 Uncharacterized protein Uncharacterized protein	A0A8I3MKG9 A0A8I3MWD6 A0A8I3N1I8 A0A8I3NBG0 A0A8I3NUL1 A0A8I3NW02 A0A8I3NZI5 A0A8I3P4E2 A0A8I3P5X5 A0A8I3PDD9 A0A8I3PHP8 A0A8I3PP24 A0A8I3RZ66 A0A8I3S2G2 A0A8I3SA30 Q2VHZ7 Q6UR05	ABCC1 ALOX15 ALOX5 ALOX5AP CYP4A11 CYP4A37 CYP4A39 CYP4B1 CYP4F22 DPEP1 DPEP2 DPEP3 GGT1 LOC119863926 LTA4H LTC4S MRP1	Canis familiaris (dog)
Apoptotic execution phase	B-cell receptor-associated protein Caspase 8 Dynamin-1-like protein Dynamin-1-like protein non-specific serine/threonine protein kinase	A0A8I3NR52 A0A8I3PR10 A0A8I3Q0S5 A0A8I3S1Q3 Q38JA9	BCAP31 CASP8 DNM1L LOC119868890 STK24	Canis familiaris (dog)
Downstream signaling of activated FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 1 Fibronectin leucine rich transmembrane protein 2 Fibronectin leucine rich transmembrane protein 3 Klotho Multifunctional fusion protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3PDH2 A0A8I3PJY6 A0A8I3RV97 A0A8I3SAY5 A0A8I3SCU1 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FLRT1 FLRT2 FLRT3 KL	Canis familiaris (dog)
Negative regulation of MET activity	E3 ubiquitin-protein ligase CBL Endophilin-A2 Epidermal growth factor receptor pathway substrate 15 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor-regulated tyrosine kinase substrate Hepatocyte growth factor Leucine rich repeats and immunoglobulin like domains 1 SH3 domain containing GRB2 like 2, endophilin A1 SH3 domain containing kinase binding protein 1 Signal transducing adaptor molecule 2 Signal transducing adaptor molecule Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase ubiquitinyl hydrolase 1	A0A8I3MBU4 A0A8I3MMN5 A0A8I3MZ64 A0A8I3N2P0 A0A8I3N8H2 A0A8I3NFB9 A0A8I3NGD3 A0A8I3NGY1 A0A8I3NKR3 A0A8I3NRM5 A0A8I3NTR3 A0A8I3P598 A0A8I3PMU1 A0A8I3PNU1 A0A8I3PT69 A0A8I3PXV2 A0A8I3Q5C2 A0A8I3QYD0 P63050 Q867B7	CBL EPS15 GRB2 HGF HGS LRIG1 MET PTPN1 PTPN2 PTPRJ RPS27A SH3GL1 SH3GL2 SH3KBP1 STAM STAM2 UBA52 UBB UBC UBCEP2 USP8	Canis familiaris (dog)
Surfactant metabolism	ATP binding cassette subfamily A member 3 Adenosine receptor A2a Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor C-type lectin domain-containing protein Coiled-coil domain containing 59 Colony stimulating factor 2 receptor subunit beta Cytoskeleton associated protein 4 Fibronectin type-III domain-containing protein GATA binding protein 6 LIM and cysteine rich domains 1 Napsin A aspartic peptidase P2Y purinoceptor 2 Palmitoyltransferase Pepsin A Pro-cathepsin H Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein C SRCR domain-containing protein Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Transcription termination factor 1 Uncharacterized protein	A0A8I3MSD7 A0A8I3MZ62 A0A8I3NCW6 A0A8I3NFK5 A0A8I3NFY6 A0A8I3NHV8 A0A8I3NQ93 A0A8I3NR35 A0A8I3NUR4 A0A8I3NUT9 A0A8I3NWG1 A0A8I3NWJ3 A0A8I3NXR2 A0A8I3NZU4 A0A8I3P3J7 A0A8I3PBB4 A0A8I3PJM9 A0A8I3Q7S8 A0A8I3RTH9 A0A8I3RVV0 A0A8I3RW10 A0A8I3S9H9 P11617 Q9GMY6	ABCA3 ADGRF5 ADORA2A ADRA2A ADRA2C CCDC59 CKAP4 CSF2RA CSF2RB CTSH GATA6 LMCD1 LOC610540 NAPSA P2RY2 PGA PGNA RDC8 SFTPB SFTPC SFTPD SLC34A1 SLC34A2 TTF1 ZDHHC2	Canis familiaris (dog)
Na+/Cl- dependent neurotransmitter transporters	Sodium- and chloride-dependent betaine transporter Sodium- and chloride-dependent glycine transporter 1 Solute carrier family 18 member A1 Solute carrier family 18 member A2 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 6 member 13 Solute carrier family 6 member 6 Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter	A0A8I3MBP6 A0A8I3MM56 A0A8I3MNK2 A0A8I3N6A1 A0A8I3N7M6 A0A8I3NCF6 A0A8I3NLL1 A0A8I3P2T9 A0A8I3PHP5 A0A8I3PME4 A0A8I3PQT8 A0A8I3PSN6 A0A8I3PV06 A0A8I3Q066 A0A8I3QQP1 A0A8I3QS48 A0A8I3RV00 A0A8I3S5V8 P27799	SLC18A1 SLC18A2 SLC22A1 SLC22A2 SLC6A1 SLC6A11 SLC6A12 SLC6A13 SLC6A14 SLC6A15 SLC6A18 SLC6A19 SLC6A2 SLC6A20 SLC6A3 SLC6A5 SLC6A6 SLC6A7 SLC6A9	Canis familiaris (dog)

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