GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **126 - 150** of **268** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
CD22 mediated BCR regulation	B-cell antigen receptor complex-associated protein alpha chain B-cell receptor CD22 CD79a molecule CD79b molecule Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A8I3MIL9 A0A8I3MUW4 A0A8I3NVL7 A0A8I3NWR3 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P501 A0A8I3P6V2 A0A8I3P941 A0A8I3PD67 A0A8I3PDA6 A0A8I3PDU9 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUN0 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWC6 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S6H5 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 P0CAN6	CD79A CD79B IGHM LYN MAG PTPN6	Canis familiaris (dog)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	B-cell receptor CD22 Beta-2-microglobulin C-type lectin domain family 4 member G C-type lectin domain-containing protein C-type lectin domain-containing protein CD19 molecule CD1a8 protein CD1b molecule CD200 molecule CD226 molecule CD300 molecule like family member g CD40 ligand CD96 molecule CD99 antigen CD99 molecule (Xg blood group) CXADR Ig-like cell adhesion molecule Complement C3 Cytotoxic and regulatory T cell molecule Fc fragment of IgG receptor Ia Hematopoietic cell signal transducer Hematopoietic progenitor cell antigen CD34 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin C1-set domain-containing protein Immunoglobulin V-set domain-containing protein Immunoglobulin V-set domain-containing protein Immunoglobulin subtype domain-containing protein Immunoglobulin subtype domain-containing protein Immunoglobulin subtype domain-containing protein Integrin beta Integrin beta Integrin beta Integrin subunit alpha 4 Integrin subunit alpha L Intercellular adhesion molecule 1 Intercellular adhesion molecule 3 Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) Intercellular adhesion molecule 5 Intercellular adhesion molecule N-terminal domain-containing protein Interferon-induced transmembrane protein 1-like Interferon-induced transmembrane protein 1 Interferon-induced transmembrane protein 1 Interferon-induced transmembrane protein 1 Interferon-induced transmembrane protein 1 Junction adhesion molecule like Killer cell lectin like receptor B1 Killer cell lectin like receptor F1 L-selectin Leukocyte-associated immunoglobulin-like receptor 1 MHC class I DLA-12 MHC class I DLA-64 MHC class I DLA-88 MHC class I-like antigen recognition-like domain-containing protein MHC class Ib Mucosal vascular addressin cell adhesion molecule 1 NKG2-D type II integral membrane protein Natural cytotoxicity triggering receptor 3 Nectin cell adhesion molecule 2 Neural proliferation, differentiation and control 1 Osteoclast associated Ig-like receptor PILR alpha associated neural protein PVR cell adhesion molecule Paired immunoglobulin-like type 2 receptor alpha Retinoic acid early-inducible protein 1 domain-containing protein SLAM family member 7 Sialic acid binding Ig like lectin 1 T cell receptor alpha variable 29/delta variable 5 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD8 alpha chain Tetraspanin Triggering receptor expressed on myeloid cells 1 Triggering receptor expressed on myeloid cells like 2 Tumor necrosis factor receptor superfamily member 5 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vascular cell adhesion molecule 1	A0A8I3MED5 A0A8I3MFY1 A0A8I3MIZ0 A0A8I3MJ11 A0A8I3MKG5 A0A8I3MKK6 A0A8I3MLN5 A0A8I3MMP8 A0A8I3MNI1 A0A8I3MPF4 A0A8I3MQ65 A0A8I3MSG1 A0A8I3MUW4 A0A8I3MV98 A0A8I3MVN4 A0A8I3MYT7 A0A8I3MYW9 A0A8I3MZ69 A0A8I3N026 A0A8I3N5J7 A0A8I3N7C0 A0A8I3NC13 A0A8I3NCT5 A0A8I3NDA5 A0A8I3NEM6 A0A8I3NG33 A0A8I3NH55 A0A8I3NHX4 A0A8I3NJ60 A0A8I3NKZ7 A0A8I3NMD0 A0A8I3NNW2 A0A8I3NQA0 A0A8I3NRG2 A0A8I3NRH8 A0A8I3NS51 A0A8I3NSU2 A0A8I3NU38 A0A8I3NUT8 A0A8I3NVH5 A0A8I3NVY4 A0A8I3NZ50 A0A8I3NZR4 A0A8I3P0Q0 A0A8I3P2B1 A0A8I3P4F9 A0A8I3P564 A0A8I3P5B9 A0A8I3P6H0 A0A8I3P7W0 A0A8I3P952 A0A8I3PAB8 A0A8I3PAY5 A0A8I3PEP1 A0A8I3PIX4 A0A8I3PNK7 A0A8I3PNL2 A0A8I3PQ78 A0A8I3PR01 A0A8I3PRY8 A0A8I3PUD7 A0A8I3PUR2 A0A8I3PXH7 A0A8I3PY46 A0A8I3PZA9 A0A8I3PZF9 A0A8I3PZP5 A0A8I3Q1E0 A0A8I3Q1J0 A0A8I3Q1N4 A0A8I3Q2J0 A0A8I3Q3A1 A0A8I3Q3A8 A0A8I3Q3K1 A0A8I3Q413 A0A8I3Q555 A0A8I3QB12 A0A8I3QW15 A0A8I3RTV0 A0A8I3RVP0 A0A8I3RVP3 A0A8I3RY39 A0A8I3RZW2 A0A8I3S091 A0A8I3S0E0 A0A8I3S0R5 A0A8I3S2Y6 A0A8I3S357 A0A8I3S3J5 A0A8I3S6T3 A0A8I3S6W3 A0A8I3S711 A0A8I3SBB8 A0A8I3SBP9 A0A8I3SBZ7 A0A8I3SC01 A0A8I3SC89 O97626 P27597 P33706 Q28270	B2M C3 CD160 CD19 CD1A8 CD1B CD1D CD200 CD226 CD247 CD300E CD300LF CD300LG CD34 CD3D CD3E CD3G CD40 CD40L CD40LG CD81 CD8A CD8B CD96 CD99 CLEC2B CLEC2D CLEC4G CRTAM CXADR DLA-12 DLA-79 DLA88 FCGR1A HCST ICAM1 ICAM2 ICAM3 ICAM4 ICAM5 ITGA4 ITGAL ITGB1 ITGB2 ITGB7 JAML KLRB1 KLRF1 KLRK1 LAIR1 LOC100683099 LOC100686511 LOC102152131 LOC119863908 LOC119864110 LOC119864112 LOC119864113 LOC119864114 LOC119868795 LOC119873404 LOC119876868 LOC119881386 LOC475935 LOC476396 LOC483396 LOC484343 LOC606890 LOC609800 MADCAM1 MAG NCR3 NCR3LG1 NECTIN2 NPDC1 OSCAR PIANP PILRA PVR SELL SIGLEC1 SIGLEC11 SLAMF7 TNFSF5 TRAV29DV5 TREM1 TREML2 VCAM1	Canis familiaris (dog)
Apoptotic execution phase	B-cell receptor-associated protein Caspase 8 Dynamin-1-like protein Dynamin-1-like protein non-specific serine/threonine protein kinase	A0A8I3NR52 A0A8I3PR10 A0A8I3Q0S5 A0A8I3S1Q3 Q38JA9	BCAP31 CASP8 DNM1L LOC119868890 STK24	Canis familiaris (dog)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	B7-1 protein CD19 molecule CD86 molecule EGF-like domain-containing protein Epiregulin Estrogen receptor beta Estrogen receptor Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor 7 Fibroblast growth factor receptor 3 Fibroblast growth factor receptor 4 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Immediate early response 3 Inducible T-cell costimulator Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin Interleukin 1 receptor accessory protein Interleukin-1 receptor-associated kinase 4 Interleukin-33 Kit ligand Klotho beta Klotho Mast/stem cell growth factor receptor Kit Mitogen-activated protein kinase Mitogen-activated protein kinase Multifunctional fusion protein Myeloid differentiation primary response protein MyD88 Neuregulin 2 Neuregulin 3 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha Phosphatidylinositol-4-phosphate 5-kinase type 1 beta Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma Phosphatidylinositol-5-phosphate 4-kinase type 2 beta Phosphoinositide-3-kinase adaptor protein 1 Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-epidermal growth factor Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Protein phosphatase 2 regulatory subunit B'beta Protein phosphatase 2 scaffold subunit Abeta Rac family small GTPase 2 Ras homolog family member G Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase Serine/threonine-protein phosphatase Striatin T cell receptor associated transmembrane adaptor 1 T-cell-specific surface glycoprotein CD28 TNF receptor-associated factor 6 Tyrosine-protein kinase receptor Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vav guanine nucleotide exchange factor 1 non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A0B4J199 A0A5F4C2B1 A0A7U3JWB8 A0A8I3MAV6 A0A8I3MIK6 A0A8I3MIK8 A0A8I3MIV9 A0A8I3MN72 A0A8I3MP09 A0A8I3MPF4 A0A8I3MRL6 A0A8I3MS02 A0A8I3MT80 A0A8I3MU82 A0A8I3MWU3 A0A8I3MZG1 A0A8I3N0H9 A0A8I3N488 A0A8I3N5M3 A0A8I3N821 A0A8I3N8J8 A0A8I3N8T5 A0A8I3N971 A0A8I3N9M7 A0A8I3NA65 A0A8I3NAC6 A0A8I3NAN8 A0A8I3NCP9 A0A8I3NEF4 A0A8I3NGY1 A0A8I3NH46 A0A8I3NH64 A0A8I3NHA2 A0A8I3NHF3 A0A8I3NIT3 A0A8I3NKX5 A0A8I3NLT7 A0A8I3NN81 A0A8I3NNZ2 A0A8I3NS74 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NVK5 A0A8I3NVV1 A0A8I3NVW9 A0A8I3NWK3 A0A8I3NXI8 A0A8I3NYK3 A0A8I3P2V4 A0A8I3P3M1 A0A8I3P3X1 A0A8I3P4L9 A0A8I3P519 A0A8I3P6D2 A0A8I3PB14 A0A8I3PJY6 A0A8I3PK39 A0A8I3PKX6 A0A8I3PMT9 A0A8I3PN81 A0A8I3PR42 A0A8I3PT69 A0A8I3PV99 A0A8I3PWD4 A0A8I3PWT3 A0A8I3PZJ3 A0A8I3PZP0 A0A8I3Q059 A0A8I3Q1C3 A0A8I3Q209 A0A8I3Q314 A0A8I3Q525 A0A8I3Q5L9 A0A8I3RPS3 A0A8I3RQD0 A0A8I3RRJ5 A0A8I3RRT3 A0A8I3RS70 A0A8I3RTN7 A0A8I3RXU6 A0A8I3RYJ5 A0A8I3S0I1 A0A8I3S0T0 A0A8I3S1W8 A0A8I3S333 A0A8I3S3N2 A0A8I3S8G3 A0A8I3SAY5 A0A8I3SBF9 E2REX2 J9P0B3 J9P3I7 J9P8K0 O97799 O97863 P01321 P62999 P79150 Q06220 Q20FD0 Q6Q7I7 Q7YR73 Q867B7 Q9TQX1	AILIM AREG BTC CD19 CD28 CD80 CD86 EGF EGFR EPGN ERBB2 ERBB3 ERBB4 EREG ESR1 ESR2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF4C FGF5 FGF6 FGF7 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 FYN GAB1 GAB2 GRB2 HBEGF HGF ICOS IER3 IL1RAP IL33 INS INSR IRAK1 IRAK4 IRS1 IRS2 KGF KIT KITLG KL KLB LCK LOC100856339 MAPK1 MAPK3 MET MGF MYD88 NRG1 NRG2 NRG3 PDGFA PDGFB PDGFRA PDGFRB PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PTPN11 RAC1 RAC2 RHOG SRC STRN TGFA TRAF6 TRAT1 VAV1	Canis familiaris (dog)
Antimicrobial peptides	BPI fold containing family A member 2 BPI fold containing family B member 1 BPI fold containing family B member 2 BPI fold containing family B member 4 BPI fold containing family B member 6 BPI fold-containing family A member 1 Bactericidal permeability-increasing protein Cathelicidin Cathepsin G Chromogranin-A Elastase, neutrophil expressed Liver-expressed antimicrobial peptide 2 Lysozyme C, spleen isozyme Peptidase inhibitor 3 Peptidoglycan recognition protein 2 Peptidoglycan-recognition protein Rerating islet-derived 3 alpha Saposin B-type domain-containing protein trypsin	A0A5F4D5H8 A0A8I3MTX9 A0A8I3NJP0 A0A8I3NK04 A0A8I3NUZ6 A0A8I3PD99 A0A8I3PIK6 A0A8I3PIZ8 A0A8I3PJC6 A0A8I3PJT2 A0A8I3PMA8 A0A8I3PU85 A0A8I3S3D7 A0A8I3S705 D3DMB4 F1PZP0 P81709 Q6TN20 Q8MJD1	BPI BPIFA1 BPIFA2 BPIFB1 BPIFB2 BPIFB4 BPIFB6 CAMP CHGA CTSG ELA2 ELANE GNLY LEAP2 LOC100687463 PGLYRP1 PGLYRP2 PI3 PRSS2 REG3A	Canis familiaris (dog)	G49108TO
Regulation of TNFR1 signaling	Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing protein 3 CAP-Gly domain containing linker protein 3 Caspase 8 Caspase 9 E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase XIAP IkappaB kinase Inhibitor of nuclear factor kappa B kinase subunit epsilon Inhibitor of nuclear factor kappa-B kinase subunit alpha MAP kinase-activating death domain protein NF-kappa-B essential modulator Optineurin RBR-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Serine/threonine-protein kinase Signal peptide peptidase like 2A Signal peptide peptidase like 2B Small ribosomal subunit protein RACK1 Spermatogenesis associated 2 TANK binding kinase 1 TNF receptor-associated factor TNFR-Cys domain-containing protein Tax1 binding protein 1 Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin B Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin conjugating enzyme E2 D3 Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A8I3MA34 A0A8I3MAP5 A0A8I3MDM0 A0A8I3MJ82 A0A8I3MKR0 A0A8I3MLM6 A0A8I3MMN5 A0A8I3MQC7 A0A8I3MSL4 A0A8I3MYA4 A0A8I3N1V1 A0A8I3N4F2 A0A8I3NEJ2 A0A8I3NFB9 A0A8I3NK16 A0A8I3NLZ9 A0A8I3NP69 A0A8I3NS04 A0A8I3P2P4 A0A8I3P499 A0A8I3PLX1 A0A8I3PRU0 A0A8I3PS24 A0A8I3PT83 A0A8I3PW29 A0A8I3PWL6 A0A8I3PZS6 A0A8I3Q155 A0A8I3Q3L1 A0A8I3QYD0 A0A8I3RSQ2 A0A8I3RUY7 A0A8I3RZA9 A0A8I3RZI9 A0A8I3S2L7 A0A8I3S5W5 A0A8I3S792 A0A8I3S794 A1E2V0 P51742 P63050 Q38IV1 Q38JA9	BIRC2 BIRC3 BIRC4 CASP8 CASP9 CHUK CLIP3 CYLD IKBKB IKBKE IKBKG IRF9 MADD MIB2 OPTN OTUD1 OTUD7B RACK1 RBCK1 RIPK1 RPS27A SPATA2 SPPL2A SPPL2B STUB1 TAX1BP1 TBK1 TNF TNFA TNFAIP3 TNFRSF1A TNFSF2 TRADD TRAF2 UBA52 UBB UBC UBCEP2 UBE2D1 UBE2D2 UBE2D3 UBE2L3 ULK1 USP2 USP21 USP4 XIAP	Canis familiaris (dog)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing protein 3 CD40 ligand LIGHT Lymphotoxin beta receptor Lymphotoxin-alpha Lymphotoxin-beta Mitogen-activated protein kinase kinase kinase 14 TNF receptor superfamily member 11a TNF receptor superfamily member 12A TNF receptor superfamily member 13C TNF receptor-associated factor TNF receptor-associated factor TNF superfamily member 13b Tumor necrosis factor (ligand) superfamily, member 12 Tumor necrosis factor ligand superfamily member Tumor necrosis factor receptor superfamily member 5	A0A8I3MDM0 A0A8I3MES0 A0A8I3MQC7 A0A8I3MWN3 A0A8I3NGJ3 A0A8I3NLQ1 A0A8I3NRP3 A0A8I3P6H0 A0A8I3PTD2 A0A8I3PZM4 A0A8I3RR83 A1E2V0 J9JHM5 J9P2Z1 J9P753 O97626 Q5WR07	BIRC2 BIRC3 CD40 CD40L CD40LG LTA LTB LTBR MAP3K14 TNFB TNFRSF11A TNFRSF12A TNFRSF13C TNFSF1 TNFSF11 TNFSF12 TNFSF13B TNFSF14 TNFSF5 TNLG1C TNLG1D TNLG7A TRAF2 TRAF3	Canis familiaris (dog)
TNFR1-induced NF-kappa-B signaling pathway	Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing protein 3 E3 ubiquitin-protein ligase XIAP IkappaB kinase Inhibitor of nuclear factor kappa-B kinase subunit alpha Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator Optineurin RBR-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Small ribosomal subunit protein RACK1 Spermatogenesis associated 2 TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TNF receptor-associated factor TNFR-Cys domain-containing protein Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Uncharacterized protein ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A8I3MA34 A0A8I3MDM0 A0A8I3MQC7 A0A8I3MSL4 A0A8I3MYA4 A0A8I3N1V1 A0A8I3N4F2 A0A8I3N7L6 A0A8I3NEJ2 A0A8I3NMB6 A0A8I3NP69 A0A8I3P2P4 A0A8I3P499 A0A8I3P4Z1 A0A8I3PLL0 A0A8I3PS24 A0A8I3PWL6 A0A8I3Q3L1 A0A8I3RSQ2 A0A8I3RUY7 A0A8I3RZA9 A0A8I3S2L7 A0A8I3S792 A0A8I3S794 A1E2V0 P51742 Q38IV1	BIRC2 BIRC3 BIRC4 CHUK CYLD IKBKB IKBKG IRF9 MAP3K7 OPTN OTUD1 OTUD7B RACK1 RBCK1 RIPK1 SPATA2 TAB1 TAB2 TAB3 TNF TNFA TNFAIP3 TNFRSF1A TNFSF2 TRADD TRAF2 USP2 USP21 USP4 XIAP	Canis familiaris (dog)
TNFR1-induced proapoptotic signaling	Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing protein 3 E3 ubiquitin-protein ligase XIAP Inhibitor of nuclear factor kappa B kinase subunit epsilon RBR-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RanBP-type and C3HC4-type zinc finger-containing protein 1 Receptor interacting serine/threonine kinase 1 Spermatogenesis associated 2 TANK binding kinase 1 TNF receptor-associated factor TNFR-Cys domain-containing protein Tumor necrosis factor receptor type 1-associated DEATH domain protein Tumor necrosis factor Ubiquitin carboxyl-terminal hydrolase CYLD	A0A8I3MDM0 A0A8I3MQC7 A0A8I3MSL4 A0A8I3MYA4 A0A8I3NEJ2 A0A8I3NK16 A0A8I3NS04 A0A8I3P2P4 A0A8I3PS24 A0A8I3Q155 A0A8I3Q3L1 A0A8I3S2L7 A1E2V0 P51742 Q38IV1	BIRC2 BIRC3 BIRC4 CYLD IKBKE IRF9 MIB2 RBCK1 RIPK1 SPATA2 TBK1 TNF TNFA TNFRSF1A TNFSF2 TRADD TRAF2 XIAP	Canis familiaris (dog)
Integrin cell surface interactions	Basigin CD44 antigen Cadherin-1 Cadherin-1 Cartilage oligomeric matrix protein Collagen type IV alpha 1 chain Collagen type IV alpha 2 chain Collagen type IV alpha 3 chain Collagen type IV alpha 4 chain Collagen type IX alpha 1 chain Collagen type IX alpha 2 Collagen type IX alpha 3 chain Collagen type XIII alpha 1 chain Collagen type XVI alpha 1 chain Collagen type XVIII alpha 1 chain Fibrillin 1 Fibronectin Ig-like domain-containing protein Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 10 Integrin subunit alpha 11 Integrin subunit alpha 1 Integrin subunit alpha 2 Integrin subunit alpha 2b Integrin subunit alpha 3 Integrin subunit alpha 4 Integrin subunit alpha 5 Integrin subunit alpha 6 Integrin subunit alpha 8 Integrin subunit alpha 9 Integrin subunit alpha D Integrin subunit alpha E Integrin subunit alpha L Integrin subunit alpha M Integrin subunit alpha V Integrin-binding sialoprotein Intercellular adhesion molecule 1 Intercellular adhesion molecule 3 Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) Intercellular adhesion molecule 5 Intercellular adhesion molecule N-terminal domain-containing protein Junctional adhesion molecule 3 Junctional adhesion molecule A Leukocyte surface antigen CD47 Lumican Mucosal vascular addressin cell adhesion molecule 1 Platelet and endothelial cell adhesion molecule 1 Secreted phosphoprotein 1 Tenascin C Thrombospondin 1 Vascular cell adhesion molecule 1 Vitronectin	A0A8I3MC22 A0A8I3MCY9 A0A8I3MJI6 A0A8I3MMP8 A0A8I3MQ67 A0A8I3N050 A0A8I3N567 A0A8I3NBM1 A0A8I3NFG9 A0A8I3NFV4 A0A8I3NG24 A0A8I3NL86 A0A8I3NM06 A0A8I3NNW2 A0A8I3NNX0 A0A8I3NS51 A0A8I3NUR7 A0A8I3NV00 A0A8I3NXU0 A0A8I3P0Q0 A0A8I3P1W2 A0A8I3P4K7 A0A8I3P4U9 A0A8I3P613 A0A8I3P684 A0A8I3P787 A0A8I3P7W0 A0A8I3PCF8 A0A8I3PCH7 A0A8I3PED8 A0A8I3PEP1 A0A8I3PHE2 A0A8I3PI20 A0A8I3PJI8 A0A8I3PMU9 A0A8I3PNK7 A0A8I3PPU8 A0A8I3PRY8 A0A8I3PUD7 A0A8I3PZA9 A0A8I3PZR7 A0A8I3Q3A8 A0A8I3Q413 A0A8I3Q8L7 A0A8I3QCJ7 A0A8I3RVE5 A0A8I3RVR5 A0A8I3RW71 A0A8I3RZG7 A0A8I3S0U4 A0A8I3S0V6 A0A8I3S131 A0A8I3S2B2 A0A8I3S700 A0A8I3S8N4 A0A8I3SBL1 E2DP67 F1PAA9	BSG CD44 CD47 CDH1 COL13A1 COL16A1 COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL9A1 COL9A2 COL9A3 COMP F11R FBN1 FN1 IBSP ICAM1 ICAM2 ICAM3 ICAM4 ICAM5 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGB1 ITGB2 ITGB3 ITGB5 ITGB6 ITGB7 ITGB8 JAM3 LOC119867047 LUM MADCAM1 PECAM1 SEBOX SPP1 THBS1 TNC VCAM1	Canis familiaris (dog)
Glycosphingolipid biosynthesis	Beta-1,3-galactosyltransferase 4 Beta-1,4-N-acetyl-galactosaminyltransferase 1 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Ceramide kinase Hexosyltransferase L-Fucosyltransferase Lactosylceramide 4-alpha-galactosyltransferase Lactosylceramide alpha-2,3-sialyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 UDP glycosyltransferase 8 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3-sialyltransferase ceramide glucosyltransferase	A0A8I3MCT3 A0A8I3MQ19 A0A8I3MWM9 A0A8I3MXG6 A0A8I3NA60 A0A8I3NB27 A0A8I3NFU6 A0A8I3NNC5 A0A8I3NPC1 A0A8I3NTR2 A0A8I3P0Y9 A0A8I3PUA8 A0A8I3PVY1 A0A8I3QHY8 A0A8I3RSF2 Q5TJE8	A4GALT B3GALNT1 B3GALT4 B4GALNT1 B4GALT5 B4GALT6 CERK FUT2 ST3GAL2 ST3GAL3 ST3GAL5 ST6GALNAC5 ST6GALNAC6 ST8SIA5 UGCG UGT8	Canis familiaris (dog)
Lactose synthesis	Beta-1,4-galactosyltransferase Lactose synthase B protein Solute carrier family 2, facilitated glucose transporter member 1	A0A8I3NRK7 A0A8I3S1K5 F1PTQ7	B4GALT1 LALBA LYZG SLC2A1	Canis familiaris (dog)	G58161NS G74621DY
O-linked glycosylation	Beta-1,4-glucuronyltransferase 1 Dolichyl-phosphate-mannose--protein mannosyltransferase Dolichyl-phosphate-mannose--protein mannosyltransferase Dystroglycan 1 Hexosyltransferase LARGE xylosyl- and glucuronyltransferase 1 LARGE xylosyl- and glucuronyltransferase 2 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 Protein O-mannose kinase	A0A8I3MY95 A0A8I3N4J0 A0A8I3NBQ3 A0A8I3NME9 A0A8I3NRN3 A0A8I3P5F6 A0A8I3P946 A0A8I3QJ22 Q5NDE9 Q9TSZ6	AGO61 B3GALNT2 B4GAT1 DAG1 GTDC2 LARGE1 LARGE2 POMGNT1 POMGNT2 POMK POMT1 POMT2	Canis familiaris (dog)
DAP12 interactions	Beta-2-microglobulin C-type lectin domain-containing protein C-type lectin domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Immunoglobulin subtype domain-containing protein Natural killer cells antigen CD94 Sialic acid binding Ig like lectin 15 TYRO protein tyrosine kinase-binding protein Triggering receptor expressed on myeloid cells 1 Uncharacterized protein Uncharacterized protein	A0A8I3MDD5 A0A8I3MMC4 A0A8I3MNY2 A0A8I3MVN4 A0A8I3MYW9 A0A8I3NKZ7 A0A8I3NMD0 A0A8I3NVH5 A0A8I3PNS2 A0A8I3PWV8 A0A8I3PXH7 A0A8I3QBX8 A0A8I3S091 A0A8I3S0A6 A0A8I3S2M3 A0A8I3S2Y6 Q38HS3	B2M CD300E CD94 CLEC5A KLRD1 LOC119863908 LOC119866326 LOC119873404 LOC476396 LOC484343 SIGLEC15 SIRPA TREM1 TYROBP	Canis familiaris (dog)
Gluconeogenesis	Beta-enolase Enolase 4 Fructose-1,6-bisphosphatase 1 Fructose-1,6-bisphosphatase isozyme 2 Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase Fructose-bisphosphate aldolase Glucose-6-phosphatase Glucose-6-phosphatase Glucose-6-phosphatase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Glyceraldehyde-3-phosphate dehydrogenase Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Phosphoglycerate kinase Phosphoglycerate kinase Phosphoglycerate mutase Phosphoglycerate mutase Pyruvate carboxylase Solute carrier family 37 member 1 Solute carrier family 37 member 2 Solute carrier family 37 member 4 Triosephosphate isomerase phosphoenolpyruvate carboxykinase (GTP) phosphopyruvate hydratase phosphopyruvate hydratase	A0A8I3MHK0 A0A8I3MJP4 A0A8I3MKD5 A0A8I3MKW3 A0A8I3MS60 A0A8I3MWF0 A0A8I3MZQ1 A0A8I3N1E7 A0A8I3N4J1 A0A8I3N504 A0A8I3ND17 A0A8I3NII5 A0A8I3NKZ1 A0A8I3NMJ6 A0A8I3P2U1 A0A8I3P9Y9 A0A8I3PK19 A0A8I3PRM7 A0A8I3PU48 A0A8I3PZE8 A0A8I3Q5N9 A0A8I3Q5Z0 A0A8I3QWQ0 A0A8I3RRW0 A0A8I3RTJ7 A0A8I3RYI2 A0A8I3S286 A0A8I3SC19	ALDOA ALDOB ALDOC ENO2 ENO3 ENO4 FBP1 FBP2 G6PC1 G6PC2 G6PC3 GAPDH GAPDHS GPI LOC106558132 PC PCK1 PCK2 PGAM1 PGAM2 PGK1 PGK2 SLC37A1 SLC37A2 SLC37A4 TPI1	Canis familiaris (dog)	G58161NS
Hyaluronan uptake and degradation	Beta-glucuronidase Beta-hexosaminidase Beta-hexosaminidase CD44 antigen Calcineurin B homologous protein 1 Hyaluronan mediated motility receptor Hyaluronidase Lymphatic vessel endothelial hyaluronan receptor 1 Sodium/hydrogen exchanger Stabilin 2	A0A8I3MHZ0 A0A8I3MY15 A0A8I3NBX1 A0A8I3NDU0 A0A8I3NYL9 A0A8I3PCF8 A0A8I3PI48 A0A8I3PNW9 A0A8I3Q0H4 A0A8I3RW87	CD44 CHP1 GUSB HEXA HEXB HMMR HYAL1 LYVE1 SLC9A1 STAB2	Canis familiaris (dog)	G35674CY
Chondroitin sulfate biosynthesis	Biglycan Brevican core protein Carbohydrate sulfotransferase 7 Carbohydrate sulfotransferase Carbohydrate sulfotransferase Carbohydrate sulfotransferase Carbohydrate sulfotransferase Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Hexosyltransferase Neurocan Sulfotransferase Versican core protein	A0A8I3MD46 A0A8I3MZ05 A0A8I3N108 A0A8I3N5J5 A0A8I3N8Z0 A0A8I3NAW4 A0A8I3NGD4 A0A8I3NHS7 A0A8I3NUF9 A0A8I3NUH2 A0A8I3P874 A0A8I3PDW3 A0A8I3PHY6 A0A8I3Q1Q4 A0A8I3Q2X9 A0A8I3Q6I3 A0A8I3RX33 E2RLE9 Q29393	BCAN BGN CHPF CHPF2 CHST11 CHST12 CHST13 CHST3 CHST7 CHST9 CHSY1 CHSY3 CSGALNACT1 CSGALNACT2 CSPG4 CSPG5 DCN DCN1C NCAN VCAN	Canis familiaris (dog)
Dermatan sulfate biosynthesis	Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Dermatan sulfate epimerase like Dermatan sulfate epimerase Neurocan Uronyl 2-sulfotransferase Versican core protein	A0A8I3MK93 A0A8I3MZW8 A0A8I3N5J5 A0A8I3N8Z0 A0A8I3NUF9 A0A8I3NUZ7 A0A8I3P874 A0A8I3PDW3 A0A8I3PHY6 Q29393	BCAN BGN CSPG4 CSPG5 DCN DCN1C DSE DSEL NCAN UST VCAN	Canis familiaris (dog)
Sensory perception of sweet, bitter, and umami (glutamate) taste	Bitter taste receptor T2R43 G protein subunit alpha transducin 3 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Inositol 1,4,5-trisphosphate receptor Taste 1 receptor member 1 Taste receptor type 1 member 3 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2	A0A8I3NKU5 A0A8I3PJF2 A0A8I3PQY2 A0A8I3PRQ9 A0A8I3Q2P2 A0A8I3Q7L4 A0A8I3QV74 A0A8I3S925 A0A8I3S929 A0A8I3SCV7 P62872 P79147 Q2ABD0 Q2ABD1 Q2ABD4 Q2ABD5 Q2ABD6 Q2ABD8 Q2ABE0	CAFA-T2R43 GNAT3 GNB1 GNB3 GNG13 ITPR3 LOC100682759 TAS1R1 TAS1R3 TAS2R1 TAS2R10 TAS2R3 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R5 TAS2R7	Canis familiaris (dog)	G58161NS
Signaling by BMP	Bone morphogenetic protein 10 Bone morphogenetic protein 2 Cerberus 1, DAN family BMP antagonist Chordin like 1 E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Follistatin-related protein 1 Gremlin Growth differentiation factor 2 Inhibin alpha chain Inhibin beta A chain Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Noggin Serine/threonine-protein kinase receptor Serine/threonine-protein kinase receptor Ski oncogene Transforming growth factor beta receptor 3 Ubiquitin conjugating enzyme E2 D3 Zinc finger FYVE domain-containing protein receptor protein serine/threonine kinase receptor protein serine/threonine kinase receptor protein serine/threonine kinase receptor protein serine/threonine kinase	A0A7I8AUV5 A0A8I3MLM6 A0A8I3MRS8 A0A8I3MVJ8 A0A8I3N281 A0A8I3N723 A0A8I3N8R4 A0A8I3NCV3 A0A8I3NHH0 A0A8I3NM89 A0A8I3NU17 A0A8I3NW84 A0A8I3NYK2 A0A8I3NZI6 A0A8I3P2D1 A0A8I3P2Y0 A0A8I3P330 A0A8I3P4Q9 A0A8I3PB34 A0A8I3PG53 A0A8I3PG60 A0A8I3PPQ3 A0A8I3PZR5 A0A8I3Q270 A0A8I3QCM6 A0A8I3RR80 A0A8I3S5B1 A0A8I3S5W5 A0A8I3SCQ0	ACVR2A ACVR2B ACVRL1 BMP10 BMP2 BMPR1A BMPR1B BMPR2 CER1 CHRDL1 FSTL1 GDF2 GREM2 INHA INHBA NOG SKI SMAD1 SMAD4 SMAD5 SMAD6 SMAD7 SMAD9 SMURF1 SMURF2 TGFBR3 UBE2D1 UBE2D3 ZFYVE16	Canis familiaris (dog)
Iron uptake and transport	Broad substrate specificity ATP-binding cassette transporter ABCG2 Cullin 1 Cullin-associated NEDD8-dissociated protein 1 Cytoplasmic aconitate hydratase F-box/LRR-repeat protein 5 FLVCR heme transporter 1 Ferritin heavy chain Ferritin light chain Ferritin Ferritin Ferritin Heme oxygenase 1 Hephaestin Iron-responsive element-binding protein 2 Lipocalin 2 NEDD8 Plasma membrane ascorbate-dependent reductase CYBRD1 Proton-coupled folate transporter S-phase kinase-associated protein 1 Solute carrier family 11 member 2 Solute carrier family 22 member 17 Solute carrier family 40 protein member 1 Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein ferroxidase heme oxygenase (biliverdin-producing)	A0A8I3ME81 A0A8I3MH42 A0A8I3MHS3 A0A8I3MKF8 A0A8I3MMN5 A0A8I3N1L5 A0A8I3N2C0 A0A8I3N2D2 A0A8I3N4B0 A0A8I3N8Y0 A0A8I3NAI4 A0A8I3NFB9 A0A8I3NP41 A0A8I3NPT2 A0A8I3NT24 A0A8I3NZI4 A0A8I3PMF7 A0A8I3Q213 A0A8I3Q9B0 A0A8I3QDX8 A0A8I3QYD0 A0A8I3RZ10 A0A8I3S0Z7 B3RFJ1 E2RFJ3 P63050 Q53VB8 Q95MP7	ABCG2 ACO1 Abcg2 CAND1 CP CUL1 CYBRD1 FBXL5 FLVCR1 FTH FTH1 FTL HEPH HMOX1 HMOX2 IREB2 LCN2 LOC119865338 LOC119878918 LOC608550 NEDD8 RPS27A SKP1 SLC11A2 SLC22A17 SLC40A1 SLC46A1 UBA52 UBB UBC UBCEP2	Canis familiaris (dog)
Regulation of Complement cascade	C3a anaphylatoxin chemotactic receptor C4a anaphylatoxin C5a anaphylatoxin chemotactic receptor 1 CD19 molecule Carboxypeptidase B2 Carboxypeptidase N subunit 1 Carboxypeptidase N subunit 2 Clusterin Complement C1q B chain Complement C1q C chain Complement C1q subcomponent subunit A Complement C1s Complement C2 Complement C3 Complement C5 Complement C5a receptor 2 Complement C7 Complement C8 alpha chain Complement C8 gamma chain Complement component C6 Complement component C8 beta chain Complement component C9 Complement factor B Complement factor I Elastase, neutrophil expressed Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MAC-inhibitory protein Membrane cofactor protein Prothrombin Serpin family G member 1 Sushi domain-containing protein Sushi domain-containing protein Sushi domain-containing protein Sushi domain-containing protein Tetraspanin Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Vitronectin complement subcomponent C1r	A0A8I3MAL2 A0A8I3MBH0 A0A8I3MDV8 A0A8I3MFV5 A0A8I3MKD7 A0A8I3MKJ7 A0A8I3MLF7 A0A8I3MPF4 A0A8I3MQ72 A0A8I3MQK6 A0A8I3MRL7 A0A8I3N180 A0A8I3N567 A0A8I3NC13 A0A8I3NH95 A0A8I3NLH3 A0A8I3NQA0 A0A8I3NQQ5 A0A8I3NT81 A0A8I3NVC1 A0A8I3NWR3 A0A8I3NYS7 A0A8I3P0T6 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P2N6 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P941 A0A8I3PD67 A0A8I3PDU9 A0A8I3PJQ7 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PTW0 A0A8I3PUA5 A0A8I3PUL5 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PUT1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3Q044 A0A8I3Q2F2 A0A8I3Q318 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3RQ73 A0A8I3RQX0 A0A8I3RSI3 A0A8I3RSN2 A0A8I3RUJ7 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S1V7 A0A8I3S6H5 A0A8I3S7V8 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7 P25473 Q8MJD1	C1QA C1QB C1QC C1R C1S C2 C3 C3AR1 C5 C5AR1 C5AR2 C6 C7 C8A C8B C8G C9 CD19 CD55 CD59 CD81 CFB CFH CFHR5 CFI CLU CPB2 CPN1 CPN2 ELA2 ELANE F2 LOC102156626 LOC481722 LOC490269 SEBOX SERPING1	Canis familiaris (dog)
Initial triggering of complement	C4a anaphylatoxin Collectin subfamily member 10 Complement C1q B chain Complement C1q C chain Complement C1q subcomponent subunit A Complement C1s Complement C2 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MBL associated serine protease 1 MBL associated serine protease 2 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein complement subcomponent C1r	A0A8I3MAL2 A0A8I3MBH0 A0A8I3MKD7 A0A8I3MRI0 A0A8I3NH95 A0A8I3NLF4 A0A8I3NQQ5 A0A8I3NWR3 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P2N6 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P941 A0A8I3PD67 A0A8I3PDU9 A0A8I3PG15 A0A8I3PJQ7 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUL5 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3RST0 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S6H5 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7	C1QA C1QB C1QC C1R C1S C2 COLEC10 FCN2 LOC481722 MASP1 MASP2	Canis familiaris (dog)	G49108TO G57321FI
TNFs bind their physiological receptors	CD27 molecule CD70 molecule EDAR associated via death domain Ectodysplasin A receptor Ectodysplasin A LIGHT Lymphotoxin-alpha Migration and invasion inhibitory protein TNF family profile domain-containing protein TNF receptor superfamily member 14 TNF receptor superfamily member 17 TNF receptor superfamily member 18 TNF receptor superfamily member 1B TNF receptor superfamily member 6b TNF receptor superfamily member 9 TNF superfamily member 13 TNF superfamily member 13b TNF superfamily member 18 TNF superfamily member 4 TNF superfamily member 8 TNFR-Cys domain-containing protein Tumor necrosis factor ligand superfamily member Tumor necrosis factor receptor superfamily member 11B Uncharacterized protein Uncharacterized protein	A0A0U5JAK9 A0A8I3MEA7 A0A8I3MKG7 A0A8I3MM10 A0A8I3MPQ0 A0A8I3N568 A0A8I3NB07 A0A8I3NFC1 A0A8I3NGJ3 A0A8I3NJU2 A0A8I3NZX5 A0A8I3P405 A0A8I3PKB9 A0A8I3PLK9 A0A8I3PMM9 A0A8I3Q3L1 A0A8I3Q7M4 A0A8I3QDG0 A0A8I3S9F2 E2R8I1 E2RP79 J9JHM5 J9P753 Q58P77 Q5WR07	CD27 CD70 EDA EDAR EDARADD LTA MIIP TNFB TNFRSF11B TNFRSF13B TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF1A TNFRSF1B TNFRSF4 TNFRSF6B TNFRSF9 TNFSF1 TNFSF11 TNFSF13 TNFSF13B TNFSF14 TNFSF18 TNFSF4 TNFSF8 TNLG1D TNLG2A TNLG2B TNLG3A TNLG7A	Canis familiaris (dog)
PD-1 signaling	CD274 molecule Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein MHC class II DR alpha chain Major histocompatibility complex, class II, DQ alpha 1 Major histocompatibility complex, class II, DQ beta 2 Programmed cell death 1 ligand 2 Programmed cell death 1 T cell receptor alpha variable 29/delta variable 5 T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A8I3MED5 A0A8I3MFY1 A0A8I3MJ11 A0A8I3MKK6 A0A8I3MV98 A0A8I3MZ69 A0A8I3NAC6 A0A8I3NNV6 A0A8I3NTK0 A0A8I3P4A1 A0A8I3P4Z0 A0A8I3P564 A0A8I3PAB8 A0A8I3PMT9 A0A8I3PR61 A0A8I3PWC6 A0A8I3S023 A0A8I3S2N1 A0A8I3S3J5 E2RKZ5 P27597 P33705	CD247 CD274 CD3D CD3E CD3G CD4 CSK DLA-DQA1 DLA-DRA HLA-DQB2 LCK PD-L1 PDCD1 PDCD1LG2 PDL1 PTPN11 PTPN6 TRAV29DV5	Canis familiaris (dog)

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