GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source Last Updated
Reactome March 20, 2024
ECODAB April 1, 2019
Displaying entries 201 - 225 of 268 in total
Pathway Name Protein Name UniProt ID Gene Symbol Organism ▲ GlyTouCan ID
Keratan sulfate degradation
  • ACAN
  • FMOD
  • GLB1
  • GLB1L
  • GLB1L2
  • GNS
  • HEXA
  • HEXB
  • KERA
  • LUM
  • OGN
  • OMD
  • PRELP
Canis familiaris (dog)
TWIK-related alkaline pH activated K+ channel (TALK)
  • KCNK16
  • KCNK17
Canis familiaris (dog)
Class A/1 (Rhodopsin-like receptors)
  • CB2
  • CMKLR1
  • CNR2
  • GPBAR1
  • GPR132
  • GPR18
  • GPR183
  • GPR35
  • GPR39
  • GPR55
  • GPR68
  • HCAR2
  • MTNR1A
  • MTNR1B
  • OXGR1
  • PTAFR
  • SUCNR1
Canis familiaris (dog)
FCGR activation
  • CD247
  • CD3G
  • FCGR1A
  • FCGR2B
  • FCGR3A
  • FGR
  • FYN
  • HCK
  • LOC478984
  • LYN
  • SRC
  • SYK
  • YES1
Canis familiaris (dog)
Creatine metabolism
  • CKB
  • CKM
  • CKMT2
  • GAMT
  • GATM
  • LOC478277
  • SLC6A11
  • SLC6A12
  • SLC6A7
  • SLC6A8
Canis familiaris (dog)
FGFR1b ligand binding and activation
  • FGF1
  • FGF10
  • FGF22
  • FGF3
  • FGFR1
  • GIPC1
  • TGFBR3
Canis familiaris (dog)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
  • ACOT8
  • ACOX2
  • Abcb11e
  • BAAT
  • BSEP
  • CYP27A1
  • CYP7A1
  • CYP7B1
  • CYP8B1
  • HSD17B4
  • HSD3B7
  • LOC119874618
  • NCOA1
  • NCOA2
  • NR1H4
  • PTGIS
  • RXRA
  • SCP2
  • SLC27A2
  • SLC27A5
Canis familiaris (dog)
Antimicrobial peptides
  • BPI
  • BPIFA1
  • BPIFA2
  • BPIFB1
  • BPIFB2
  • BPIFB4
  • BPIFB6
  • CAMP
  • CHGA
  • CTSG
  • ELA2
  • ELANE
  • GNLY
  • LEAP2
  • LOC100687463
  • PGLYRP1
  • PGLYRP2
  • PI3
  • PRSS2
  • REG3A
Canis familiaris (dog)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
  • AILIM
  • AREG
  • BTC
  • CD19
  • CD28
  • CD80
  • CD86
  • EGF
  • EGFR
  • EPGN
  • ERBB2
  • ERBB3
  • ERBB4
  • EREG
  • ESR1
  • ESR2
  • FGF1
  • FGF10
  • FGF16
  • FGF17
  • FGF18
  • FGF19
  • FGF20
  • FGF22
  • FGF23
  • FGF3
  • FGF3A
  • FGF4
  • FGF4B
  • FGF4C
  • FGF5
  • FGF6
  • FGF7
  • FGF7A
  • FGF7B
  • FGF8
  • FGF8B
  • FGF9
  • FGFR1
  • FGFR2
  • FGFR3
  • FGFR4
  • FLT3
  • FLT3LG
  • FRS2
  • FYN
  • GAB1
  • GAB2
  • GRB2
  • HBEGF
  • HGF
  • ICOS
  • IER3
  • IL1RAP
  • IL33
  • INS
  • INSR
  • IRAK1
  • IRAK4
  • IRS1
  • IRS2
  • KGF
  • KIT
  • KITLG
  • KL
  • KLB
  • LCK
  • LOC100856339
  • MAPK1
  • MAPK3
  • MET
  • MGF
  • MYD88
  • NRG1
  • NRG2
  • NRG3
  • PDGFA
  • PDGFB
  • PDGFRA
  • PDGFRB
  • PIK3AP1
  • PIK3CA
  • PIK3CB
  • PIK3CD
  • PIK3R1
  • PIK3R2
  • PIP4K2A
  • PIP4K2B
  • PIP4K2C
  • PIP5K1A
  • PIP5K1B
  • PIP5K1C
  • PPP2CA
  • PPP2CB
  • PPP2R1A
  • PPP2R1B
  • PPP2R5A
  • PPP2R5B
  • PPP2R5C
  • PPP2R5D
  • PPP2R5E
  • PTPN11
  • RAC1
  • RAC2
  • RHOG
  • SRC
  • STRN
  • TGFA
  • TRAF6
  • TRAT1
  • VAV1
Canis familiaris (dog)
Lectin pathway of complement activation
  • COLEC10
  • FCN2
  • MASP1
  • MASP2
Canis familiaris (dog)
Signaling by PDGF
  • COL4A1
  • COL4A2
  • COL4A3
  • COL4A4
  • COL4A5
  • COL9A1
  • COL9A2
  • COL9A3
  • FURIN
  • PDGFA
  • PDGFB
  • PDGFC
  • PDGFD
  • PDGFRA
  • PDGFRB
  • PLAT
  • PLG
  • PTPN12
  • SPP1
  • THBS1
  • THBS2
  • THBS3
  • THBS4
Canis familiaris (dog)
Role of phospholipids in phagocytosis
  • CD247
  • CD3G
  • FCGR1A
  • FCGR2B
  • FCGR3A
  • LOC478984
  • PIK3CA
  • PIK3CB
  • PIK3R1
  • PIK3R2
  • PLA2G6
  • PLCG1
  • PLCG2
  • PLD1
  • PLD2
  • PLD3
  • PLD4
  • PLPP4
  • PLPP5
  • PRKCD
  • PRKCE
  • SYK
Canis familiaris (dog)
Electric Transmission Across Gap Junctions
  • GJA10
  • GJC1
  • GJD2
  • PANX
  • PANX1
  • PANX2
Canis familiaris (dog)
Reuptake of GABA
  • SLC6A1
  • SLC6A11
  • SLC6A12
  • SLC6A13
Canis familiaris (dog)
Opsins
  • OPN1LW
  • OPN1SW
  • OPN3
  • OPN4
  • OPN5
  • RCP
  • RGR
  • RHO
  • RRH
Canis familiaris (dog)
Lewis blood group biosynthesis
  • B3GALT2
  • B3GALT4
  • B3GALT5
  • B4GALNT2
  • FUT10
  • FUT11
  • FUT2
  • FUT4
  • FUT5
  • FUT7
  • FUT9
  • ST3GAL3
  • ST3GAL4
  • ST3GAL6
  • ST6GALNAC6
Canis familiaris (dog)
p130Cas linkage to MAPK signaling for integrins
  • APBB1IP
  • BCAR1
  • CRK
  • F8VWF
  • FN1
  • ITGA2B
  • ITGB3
  • PTK2
  • RAP1A
  • RAP1B
  • SRC
  • TLN1
  • VWF
Canis familiaris (dog)
Negative regulation of FGFR3 signaling
  • CBL
  • FGF1
  • FGF16
  • FGF17
  • FGF18
  • FGF20
  • FGF23
  • FGF3A
  • FGF4
  • FGF4B
  • FGF4C
  • FGF5
  • FGF7A
  • FGF8
  • FGF8B
  • FGF9
  • FGFR3
  • FRS2
  • GRB2
  • MAPK1
  • MAPK3
  • PTPN11
  • RPS27A
  • UBA52
  • UBB
  • UBC
  • UBCEP2
Canis familiaris (dog)
Sodium/Calcium exchangers
  • CALM2
  • NCX1
  • SLC24A2
  • SLC24A3
  • SLC24A4
  • SLC24A5
  • SLC8A1
  • SLC8A2
  • SLC8A3
  • SLC8B1
  • SRI
Canis familiaris (dog)
FGFR1c and Klotho ligand binding and activation
  • FGF23
  • FGF8B
  • FGFR1
  • KL
Canis familiaris (dog)
Scavenging by Class A Receptors
  • APOA1
  • APOB
  • APOE
  • CALR
  • GRP94
  • HSP90B1
  • HSPC4
  • MARCO
  • MSR1
  • SCGB3A2
  • TRA1
Canis familiaris (dog)
Glycolysis
  • ADPGK
  • ALDOA
  • ALDOB
  • ALDOC
  • BPGM
  • ENO2
  • ENO3
  • ENO4
  • GAPDH
  • GAPDHS
  • GCK
  • GNPDA1
  • GNPDA2
  • GPI
  • HK1
  • HK2
  • HK3
  • HKDC1
  • LOC106558132
  • PFKL
  • PFKM
  • PFKP
  • PGAM1
  • PGAM2
  • PGK1
  • PGK2
  • PGM2L1
  • PKLR
  • TPI1
Canis familiaris (dog)
Dermatan sulfate biosynthesis
  • BCAN
  • BGN
  • CSPG4
  • CSPG5
  • DCN
  • DCN1C
  • DSE
  • DSEL
  • NCAN
  • UST
  • VCAN
Canis familiaris (dog)
Interleukin-1 signaling
  • CHUK
  • CUL1
  • IKBKB
  • IKBKG
  • IL1A
  • IL1B
  • IL1R1
  • IL1R2
  • IL1RAP
  • IL1RN
  • IRAK1
  • IRAK2
  • IRAK3
  • IRAK4
  • LOC100686569
  • LOC100687259
  • LOC119881719
  • LOC610717
  • MAP2K6
  • MAP3K3
  • MAP3K7
  • MYD88
  • NFKB1
  • NFKBIA
  • PELI1
  • PELI2
  • PELI3
  • PSMA1
  • PSMA2
  • PSMA3
  • PSMA4
  • PSMA5
  • PSMA7
  • PSMA8
  • PSMB1
  • PSMB10
  • PSMB2
  • PSMB3
  • PSMB5
  • PSMB6
  • PSMB7
  • PSMB8
  • PSMB9
  • PSMC1
  • PSMC2
  • PSMC3
  • PSMC4
  • PSMC5
  • PSMD1
  • PSMD10
  • PSMD11
  • PSMD12
  • PSMD13
  • PSMD14
  • PSMD2
  • PSMD3
  • PSMD4
  • PSMD6
  • PSMD7
  • PSMD8
  • PSMD9
  • PSME1
  • PSME2
  • PSME4
  • PSMF1
  • RBX1
  • RELA
  • RPS27A
  • SKP1
  • SQSTM1
  • TAB1
  • TAB2
  • TAB3
  • TOLLIP
  • TRAF6
  • UBA52
  • UBB
  • UBC
  • UBCEP2
  • UBE2N
Canis familiaris (dog)
PD-1 signaling
  • CD247
  • CD274
  • CD3D
  • CD3E
  • CD3G
  • CD4
  • CSK
  • DLA-DQA1
  • DLA-DRA
  • HLA-DQB2
  • LCK
  • PD-L1
  • PDCD1
  • PDCD1LG2
  • PDL1
  • PTPN11
  • PTPN6
  • TRAV29DV5
Canis familiaris (dog)

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024