GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **226 - 250** of **252** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
Nicotinate metabolism	5'-nucleotidase Glutamine-dependent NAD(+) synthetase Mibp protein NAD(+) kinase Nicotinamide-nucleotide adenylyltransferase Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2	A5PLA8 E9QH56 Q568T8 Q6PC93 Q7SXU4 Q7ZW81	cb1024 id:ibd5068 im:7144541 mibp nadka nadsyn1 nmnat1 nmnat2 nt5e urk zgc:110083 zgc:110243 zgc:63784	Danio rerio (zebrafish)
Energy dependent regulation of mTOR by LKB1-AMPK	5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit gamma-1 Acetyl-CoA carboxylase kinase GTP-binding protein Rheb Neutral amino acid transporter 9 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory-associated protein of MTOR, complex 1 Serine/threonine-protein kinase TOR Target of rapamycin complex subunit lst8	A0A0R4IFI0 A5WUM0 E7FA90 Q06RG6 Q08BA4 Q0P3X8 Q502N9 Q503S6 Q6DEG4 Q6DHM2 Q6PC18 Q6PCS7 Q7ZUI2 Q803V5	RRAGB cb116 frap1 gbl im:7154392 lamtor2 lamtor3 lamtor4 lamtor5 lst8 mapksp1 mlst8 mtor prkaa1 prkab1a prkag1 rheb rptor rraga rragc rragca sb:cb130 si:dkey-176g4.2 slc38a9 tor wu:fa94c10 wu:fa94d09 wu:fc22h08 wu:fc68h09 wu:fd12h04 zgc:111971 zgc:56499 zgc:63896 zgc:73144 zgc:92228	Danio rerio (zebrafish)
Macroautophagy	5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit gamma-1 Acetyl-CoA carboxylase kinase Activating molecule in BECN1-regulated autophagy protein 1B Autophagy protein 5 Autophagy-related protein 101 Autophagy-related protein 13 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4c Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cysteine protease ATG4B Cysteine protease atg4da Cysteine protease Cysteine protease Dynein light chain GABA(A) receptor-associated protein-like 2 GABA(A) receptor-associated protein GTP-binding protein Rheb Gamma-aminobutyric acid receptor-associated protein-like MAP1 light chain 3-like protein 2 Map1lc3b protein Microtubule-associated protein 1 light chain 3 alpha Neutral amino acid transporter 9 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory-associated protein of MTOR, complex 1 Serine/threonine-protein kinase TOR Target of rapamycin complex subunit lst8 Ubiquitin-like protein ATG12 Ubiquitin-like-conjugating enzyme ATG10 WD repeat domain phosphoinositide-interacting protein 1 WD repeat domain phosphoinositide-interacting protein 3 WD repeat domain phosphoinositide-interacting protein 4	A0A0R4IFI0 A5WUM0 B0UXH0 E7FA90 F1RDC0 F5ATB4 Q06RG6 Q08BA4 Q0P3X8 Q3B736 Q3B7E0 Q4VBK1 Q502N9 Q503S6 Q503V0 Q5BL99 Q6DEG4 Q6DG88 Q6DH82 Q6DHM2 Q6IQ73 Q6IQ96 Q6NX90 Q6NY88 Q6PBQ2 Q6PC18 Q6PCS7 Q6PSS4 Q6TH05 Q7SYE0 Q7T305 Q7ZUD8 Q7ZUI2 Q7ZUW6 Q7ZUX3 Q7ZW25 Q7ZWC0 Q803V5 R4GER2 X1WHY6	Atg12 GABARAPL2 KM0005 MAP1-LC3A MAP1-LC3B MAP1-LC3C Map1lc3 RRAGB ambra1b apg4b apg4c apg5l atg10 atg101 atg12 atg13 atg4a atg4b atg4c atg4cl atg4da atg5 bc2 cb116 cb741 chmp2a chmp2ba chmp3 chmp4b chmp4c chmp6 chmp6l chmp7 dlc-1 dnl2 dnl2l dynll2a dynll2b frap1 gabarap gabarapa gabarapl2 gbl im:7153729 im:7154392 lamtor2 lamtor3 lamtor4 lamtor5 lst8 map1lc3a map1lc3b map1lc3c mapksp1 mg:bb02b03 mlst8 mtor prkaa1 prkab1a prkag1 rheb rptor rraga rragc rragca sb:cb130 si:ch211-212h16.5 si:ch211-224m9.5 si:dkey-176g4.2 slc38a9 tor vps24 wdr45 wdr45b wdr45l wipi1 wipi3 wipi4 wu:fa94c10 wu:fa94d09 wu:fb60g11 wu:fc22h08 wu:fc56g07 wu:fc68h09 wu:fd12h04 wu:fj43a09 zgc:100934 zgc:110812 zgc:111958 zgc:111971 zgc:123341 zgc:56434 zgc:56499 zgc:56565 zgc:63896 zgc:64205 zgc:66081 zgc:73144 zgc:77094 zgc:86888 zgc:92228 zgc:92319	Danio rerio (zebrafish)
G beta:gamma signalling through PI3Kgamma	3-phosphoinositide-dependent protein kinase 1 Rho-related GTP-binding protein RhoA-C non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	E7EXT6 Q6NZV1 Q7T2E8 Q8UUX0	akt2 akt3b cb945 pdpk1b rhoac zgc:77318	Danio rerio (zebrafish)
RHO GTPases activate PKNs	3-phosphoinositide-dependent protein kinase 1 Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1, regulatory (Inhibitor) subunit 14A Ras-related C3 botulinum toxin substrate 1 Rho-related GTP-binding protein RhoA-C Serine/threonine-protein kinase N2 Serine/threonine-protein phosphatase protein kinase C protein kinase C	A4QNX9 A7MBL8 E7F7I3 Q567W8 Q6DRG7 Q6NZV1 Q7T2E8 Q7T313 Q7ZSZ9	CPI-17 Pp1alpha-96A im:7147597 mbs mypt1 pdpk1b pkn1b pkn2 pkn3 ppp1cbl ppp1r12a ppp1r14a ppp1r14aa prk2 prkcl2 rac1 rac1a rhoac wu:fa14b10 wu:fd16e02 zgc:110700 zgc:55823 zgc:55917 zgc:64169 zgc:77318 zgc:86934	Danio rerio (zebrafish)
PI3K/AKT Signaling	3-phosphoinositide-dependent protein kinase 1 Betacellulin, epidermal growth factor family member Epigen Esr2a protein Estrogen receptor Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 2a Kit ligand Klotho Mast/stem cell growth factor receptor kita Neuregulin 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphoinositide 3-kinase adapter protein 1 Phosphoinositide-3-kinase, regulatory subunit 3A (gamma) Platelet-derived growth factor receptor alpha Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Putative fibroblast growth factor 1 Rac family small GTPase 2 Ras homolog family member Gb Ras-related C3 botulinum toxin substrate 1 Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Serine/threonine-protein kinase Sgk1 Striatin non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0R4INZ6 A0A0R4IUJ2 A0A0R4IWG0 A0A2R8Q0D8 A1L1U1 A9JRW9 B0S6V7 B3DGE3 B3DHG9 B8LFF6 E7EXT6 E7F251 E7FGA4 F1QAD7 F1QIR0 F1RC43 O57341 P48802 P57717 Q08CD2 Q1JPZ3 Q1XG76 Q38PL0 Q56JH6 Q5EBY4 Q5G254 Q5MK87 Q5RKN6 Q5TLE1 Q5TLE2 Q6IQN5 Q6NZV1 Q6PBT8 Q6PC73 Q6SJP8 Q7SYE7 Q7SZF7 Q7ZSZ9 Q7ZTW4 Q7ZU32 Q803F2 Q8AY90 Q8JFR5 Q8UUX0 Q90Z00 Q9DE49 Q9DFC9	ARHG EGFR12 EGFR15 ER[b]2 ER[b]a NRG2b akt2 akt3b btc cb945 dob egfr egfra epgn erbb2 erbb3 erbb3b erbb4 erbb4a erbeta2 esr esr1 esr2a fb18e12 fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a grb2 grb2a grb2b hbegfa id:ibd5158 kit kita kitla kitlga kl nr3a1 nrg2b pdgfab pdgfbb pdgfra pdpk1b pik3ap1 pik3ca pik3cb pik3cd pik3r1 pik3r2 pik3r3a rac1 rac1a rac2 rhog rhogb sgk sgk1 si:ch211-227n20.1 si:dkey-21e2.2 si:dkeyp-74c5.3 sparse src strn wu:fb05c08 wu:fb16a12 wu:fb18e12 wu:fb34e06 wu:fb65b05 wu:fc32c12 wu:fc89b01 wu:fd11d03 wu:fd16e02 wu:fk30f01 wu:fk56b03 wu:fv70f10 zfER-beta2 zfER[b]2 zgc:103549 zgc:109774 zgc:153249 zgc:194535 zgc:55823 zgc:55848 zgc:55917 zgc:63473 zgc:63601 zgc:73077 zgc:73230 zgc:77318 zgc:86686 zgc:86934	Danio rerio (zebrafish)
Hedgehog ligand biogenesis	26S protease regulatory subunit 10B 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11B 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 (Fragment) Derlin E3 ubiquitin-protein ligase synoviolin Endoplasmic reticulum lectin Endoplasmic reticulum lectin Hedgehog protein Proteasome (Prosome, macropain) 26S subunit, ATPase, 1a Proteasome (Prosome, macropain) 26S subunit, ATPase, 1b Proteasome 20S subunit beta 11b Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4B Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-1 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Protein disulfide-isomerase Sonic hedgehog protein Tiggy-winkle hedgehog protein Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A0R4IPV5 A3KNN5 A3KNS3 B0R1D0 B3DG31 F1QGH9 F1QK93 F1QR78 F1R2X6 H1ACM0 O57330 O57332 Q08C06 Q3B7P7 Q4V918 Q4VBR8 Q4VBS8 Q6AZC1 Q6DGX8 Q6DGY8 Q6DHI9 Q6DRD2 Q6DRF3 Q6IQ72 Q6IQC6 Q6IQD0 Q6IQH4 Q6NYV1 Q6P0I2 Q6TGV5 Q6TGV6 Q7SXA3 Q7T3B1 Q7ZU20 Q7ZU69 Q7ZU99 Q7ZUJ8 Q7ZV77 Q7ZWD1 Q7ZWE5 Q7ZYX7 Q801W1 Q803G0 Q803I8 Q8AW07 Q90419 Q92008 Q9PTH5 Q9PUC4 Q9PUS3	CH211-265P12.8 LMP7 PA28-gamma PSMA5 PSMB9A PSMD10 Psma2 Psmb11b Y beta1 beta1ia beta2i beta5 beta5ia beta5tb cdc48 derl2 erlec1 etID309919.2 fa93g07 fb17c09 fb20g04 fb49a10 fc34f08 fj42d12 fk89d05 gankyrin hha hm:zeh0386 hrd1 ihh ihha ik:tdsubc_1f2 im:6909944 lmp2 lmp7 macropain os9 p4hb prosome psma1 psma2 psma2a psma2b psma3 psma4 psma5 psma6b psma7 psma8 psmb1 psmb10 psmb11b psmb12 psmb13a psmb2 psmb3 psmb5 psmb6 psmb8 psmb8a psmb9 psmb9a psmc1 psmc1a psmc1b psmc2 psmc4 psmc5 psmc6 psmd1 psmd10 psmd11b psmd12 psmd13 psmd14 psmd3 psmd4 psmd4a psmd6 psmd7 psmd8 psme1 psme2 psme3 psme4b rps27a sb:cb309 shh shha shhb si:rp71-45k5.4 si:zc14a17.13 syvn1 tdsubc_1f2 twhh uba52 unp309 unp310 vcp vhh1 wu:fa14g03 wu:fa66f04 wu:fa91f08 wu:fa93g07 wu:faa49c06 wu:fb05d04 wu:fb11d10 wu:fb17c09 wu:fb19c08 wu:fb20g04 wu:fb23a11 wu:fb38a06 wu:fb49a10 wu:fb59c07 wu:fb98h03 wu:fc34f08 wu:fc49f02 wu:fc85c10 wu:fe05d10 wu:fe38b10 wu:fi03c01 wu:fi15g10 wu:fj14c10 wu:fj22d05 wu:fj42d12 wu:fk28c01 wu:fk89d05 wu:fu88b08 x xx:tdsubc_1f2 y zgc:109707 zgc:109823 zgc:110363 zgc:110436 zgc:110710 zgc:114044 zgc:123344 zgc:153838 zgc:162272 zgc:55284 zgc:55818 zgc:56176 zgc:56374 zgc:56377 zgc:56471 zgc:56516 zgc:63709 zgc:63995 zgc:65867 zgc:66168 zgc:77139 zgc:77369 zgc:77482 zgc:86762 zgc:86820 zgc:86833 zgc:86851 zgc:86923 zgc:91842 zgc:92282 zgc:92464 zgc:92596 zgc:92716 zgc:92726 zgc:92791	Danio rerio (zebrafish)
Hedgehog 'on' state	26S protease regulatory subunit 10B 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11B 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 (Fragment) Cilium assembly protein DZIP1 Cullin 3b E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase G-protein coupled receptor 161 Kinesin-like protein kif7 Numb Proteasome (Prosome, macropain) 26S subunit, ATPase, 1a Proteasome (Prosome, macropain) 26S subunit, ATPase, 1b Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-1 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Serine/threonine-protein kinase ULK3 Speckle-type POZ protein-like A Speckle-type POZ protein Suppressor of fused homolog Transcriptional activator GLI3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Zinc finger protein GLI2	A3KNN5 A4FUL3 A4IG43 B0R1D0 B3DG31 B3DIU1 F1QGH9 F1QK93 F1QR78 O57330 O57332 Q1XD15 Q3B7P7 Q4V918 Q4VBR8 Q58G59 Q5BL35 Q6AZC1 Q6DGX8 Q6DGY8 Q6DHI9 Q6DRD2 Q6DRF3 Q6IQ72 Q6IQC6 Q6IQD0 Q6IQH4 Q6NYV1 Q6TGV5 Q6TGV6 Q6U6Z9 Q7SXA3 Q7T019 Q7T330 Q7T3B1 Q7ZU20 Q7ZU69 Q7ZUJ8 Q7ZV77 Q7ZVZ9 Q7ZWD1 Q7ZWE5 Q7ZYX7 Q801W1 Q8AW07 Q90X46 Q9PTH5 Q9PUC4 Q9PUS3 Q9YGS4 U6C7R6	CH211-265P12.8 LMP7 PA28-gamma PSMA5 PSMB9A PSMD10 Psma2 Su(fu) Y beta1 beta1ia beta2i beta5 beta5ia cos2 cul3 cul3b dre dzip1 etID309919.2 fa93g07 fb17c09 fb20g04 fb49a10 fc34f08 fc85b05 fi39e05 fj42d12 fk89d05 gankyrin gli2 gli2a gli3 gpr161 hm:zeh0386 igu ik:tdsubc_1f2 im:6909944 im:7137515 im:7142603 itch itcha itchb kif7 lmp2 lmp7 macropain numb prosome psma1 psma2 psma2a psma2b psma3 psma4 psma5 psma6b psmb1 psmb10 psmb12 psmb13a psmb2 psmb3 psmb5 psmb6 psmb8 psmb8a psmb9 psmb9a psmc1 psmc1a psmc1b psmc2 psmc4 psmc5 psmc6 psmd1 psmd10 psmd11b psmd12 psmd13 psmd14 psmd3 psmd4 psmd4a psmd6 psmd7 psmd8 psme1 psme2 psme3 rbx1 rps27a sb:eu762 si:rp71-45k5.4 si:zc14a17.13 spop spopl spopla sufu tdsubc_1f2 uba52 ulk3 unp309 unp310 wu:fa14g03 wu:fa66f04 wu:fa91f08 wu:fa93g07 wu:faa49c06 wu:fb05d04 wu:fb11d10 wu:fb17c09 wu:fb19c08 wu:fb20g04 wu:fb23a11 wu:fb38a06 wu:fb49a10 wu:fb59c07 wu:fb98h03 wu:fc34f08 wu:fc49f02 wu:fc85b05 wu:fc85c10 wu:fe05d10 wu:fe38b10 wu:fi03c01 wu:fi39e05 wu:fj14c10 wu:fj22d05 wu:fj42d12 wu:fk89d05 wu:fu88b08 x xx:tdsubc_1f2 y yot you-too zgc:109707 zgc:109823 zgc:110363 zgc:110710 zgc:114044 zgc:123344 zgc:136444 zgc:162272 zgc:55284 zgc:55818 zgc:56176 zgc:56374 zgc:56377 zgc:56471 zgc:56516 zgc:63709 zgc:63995 zgc:65867 zgc:66168 zgc:77369 zgc:77482 zgc:86762 zgc:86820 zgc:86833 zgc:86851 zgc:86923 zgc:91842 zgc:92282 zgc:92464 zgc:92596 zgc:92716 zgc:92726 zgc:92791	Danio rerio (zebrafish)
Ub-specific processing proteases	26S protease regulatory subunit 10B 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11B 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 (Fragment) Androgen receptor Ataxin 7 Beclin-1 Beta-2 adrenergic receptor Cell division cycle 20 homolog Cellular tumor antigen p53 Cyclin-A1 Cyclin-A2 E3 ubiquitin-protein ligase SMURF2 E3 ubiquitin-protein ligase Siah2 Histone H2A Histone H2A Histone H2B 1/2 Histone H2B 3 Histone H2B Histone H2B Histone H2B Histone acetyltransferase KAT2A Insulin-degrading enzyme Kelch-like ECH-associated protein 1B Methionine adenosyltransferase 2 subunit beta Mitochondrial Rho GTPase 1-A Mitochondrial import receptor subunit TOM20 homolog B Mitochondrial import receptor subunit TOM70 Mothers against decapentaplegic homolog 1 Mothers against decapentaplegic homolog 2 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog NF-kappa-B essential modulator (Fragment) Proteasomal ubiquitin receptor ADRM1 Proteasome (Prosome, macropain) 26S subunit, ATPase, 1a Proteasome (Prosome, macropain) 26S subunit, ATPase, 1b Proteasome 20S subunit beta 11b Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4B Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-1 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta RING-type E3 ubiquitin transferase RNA helicase RuvB-like 1 SDS3 homolog, SIN3A corepressor complex component Serine/threonine-protein kinase receptor TNF receptor-associated factor 6 TNF receptor-associated factor Transcription initiation factor TFIID subunit 10 Transcriptional adapter 2-beta Transcriptional adapter 3 Transformation/transcription domain-associated protein Ubiquitin carboxyl-terminal hydrolase 13 Ubiquitin carboxyl-terminal hydrolase 16 Ubiquitin carboxyl-terminal hydrolase 20 Ubiquitin carboxyl-terminal hydrolase 22 Ubiquitin carboxyl-terminal hydrolase 30 Ubiquitin carboxyl-terminal hydrolase 33 Ubiquitin carboxyl-terminal hydrolase 37 Ubiquitin carboxyl-terminal hydrolase 42 isoform X1 Ubiquitin carboxyl-terminal hydrolase 44 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein LOC100126107 Voltage-dependent anion-selective channel protein 1 Voltage-dependent anion-selective channel protein 2 Voltage-dependent anion-selective channel protein 3 peptidyl-tRNA hydrolase peptidylprolyl isomerase	A0A0E3D804 A0A0R4IL71 A0A0R4ILY5 A0A0R4ITC5 A0A0R4IU39 A0A0R4IXF6 A0A2R8Q1W5 A2BGT0 A3KNN5 A4GT83 A4QNV7 A5PLF8 A5PMR2 A5PN09 A6H8I0 A7E2M8 A7MCA8 A8HAL1 A9JRZ0 B0EXP7 B0R1D0 B3DG31 B3DJF8 B8JJJ1 E7F640 E7F6T8 E7FEV5 F1Q6B2 F1QFS9 F1QGH4 F1QGH9 F1QHG7 F1QK93 F1QR78 F1QY38 F1R2X6 F1RCP1 H1ACM0 O57330 O57332 P79734 Q1LVD6 Q1MT86 Q1MTK1 Q3B7P7 Q4V918 Q4VBR8 Q503N9 Q5BJA5 Q5BJJ6 Q5XJK2 Q6AZC1 Q6DGX8 Q6DGY8 Q6DH66 Q6DHI9 Q6DRD2 Q6DRF3 Q6IQ72 Q6IQC6 Q6IQD0 Q6IQH4 Q6IWL4 Q6NV43 Q6NVC5 Q6NWC1 Q6NYV1 Q6NZ09 Q6NZT3 Q6P0I2 Q6P3J6 Q6PBY6 Q6PC60 Q6TGV5 Q6TGV6 Q7SXA3 Q7SY21 Q7SYL3 Q7T3B1 Q7ZTT0 Q7ZU20 Q7ZU69 Q7ZUJ8 Q7ZUM8 Q7ZV39 Q7ZV77 Q7ZWD1 Q7ZWE5 Q7ZYX7 Q801W1 Q803B3 Q8AW07 Q8AWD0 Q8AWW7 Q8AY15 Q9I8V2 Q9I9P9 Q9PTH5 Q9PUC4 Q9PUS3 R4GE15	CH211-129M12.3 CH211-265P12.8 CycA2 LMP7 LOC100332229 LOC559473 LOC570661 MDA5a MDA5b NR3C4 PA28-gamma PSMA5 PSMB9A PSMD10 Psma2 Psmb11b TOM70 VDAC1 Y ada3 adrb2b adrm1b ar atxn7 becn1 beta1 beta1ia beta2i beta5 beta5ia beta5tb cb671 ccna1 ccna2 cdc20 chunp6924 cylda drp53 etID309919.2 fa13f11 fa93g07 fb17c09 fb20g04 fb49a10 fc34f08 fd14f08 fj33c07 fj42d12 fj60c10 fk89d05 fkbp8 gankyrin h2af1al h2afx1 h2ax1 hist2h2l hm:zeh0386 ide ifih1 ik:tdsubc_1f2 ikbkg im:6899389 im:6909944 im:7146383 kat2a keap1b lmp2 lmp7 macropain madh1 madh2 madh3 madh3a madh7 mat2b mul1b nemo prosome psma1 psma2 psma2a psma2b psma3 psma4 psma5 psma6b psma7 psma8 psmb1 psmb10 psmb11b psmb12 psmb13a psmb2 psmb3 psmb5 psmb6 psmb8 psmb8a psmb9 psmb9a psmc1 psmc1a psmc1b psmc2 psmc4 psmc5 psmc6 psmd1 psmd10 psmd11b psmd12 psmd13 psmd14 psmd3 psmd4 psmd4a psmd6 psmd7 psmd8 psme1 psme2 psme3 psme4b ptrh2 rhot1a rps27a ruvbl1 si:ch211-113a14.29 si:dkey-72l14.8 si:dkey-81j5.2 si:rp71-11b17.7 si:rp71-45k5.4 si:zc14a17.13 siah2 siah2l siaz smad1 smad2 smad3 smad3a smad7 smurf2 suds3 tada2b tada3 tada3l taf10 tdsubc_1f2 tgfbr1b tomm20b tomm70a tp53 traf2b traf6 trrap uba52 unp309 unp310 usp13 usp14 usp16 usp20 usp22 usp30 usp33 usp37 usp42 usp44 usp49 usp5 vdac1 vdac2 wu:fa01a08 wu:fa06b05 wu:fa13f11 wu:fa14g03 wu:fa66f04 wu:fa91f08 wu:fa93g07 wu:fa98a10 wu:fa99e03 wu:faa49c06 wu:fb05d04 wu:fb11d10 wu:fb17c09 wu:fb19c08 wu:fb20g04 wu:fb23a11 wu:fb36d11 wu:fb38a06 wu:fb49a10 wu:fb50g11 wu:fb59c07 wu:fb98h03 wu:fc21h02 wu:fc34f08 wu:fc49f02 wu:fc61g08 wu:fc85c10 wu:fd14f08 wu:fe05d10 wu:fe38b10 wu:fe49f10 wu:fi03c01 wu:fi20d12 wu:fi36f03 wu:fi41g10 wu:fj09f02 wu:fj14c10 wu:fj22d05 wu:fj33c07 wu:fj42d12 wu:fj58b04 wu:fj60c10 wu:fk28c01 wu:fk63d09 wu:fk89d05 wu:fu88b08 x xx:tdsubc_1f2 y zgc:109707 zgc:109823 zgc:109954 zgc:110363 zgc:110710 zgc:111869 zgc:112234 zgc:113492 zgc:114044 zgc:123344 zgc:162188 zgc:162272 zgc:162603 zgc:165594 zgc:173585 zgc:173587 zgc:194998 zgc:55284 zgc:55795 zgc:55818 zgc:55949 zgc:56176 zgc:56235 zgc:56374 zgc:56377 zgc:56471 zgc:56516 zgc:56685 zgc:63536 zgc:63709 zgc:63995 zgc:65867 zgc:66168 zgc:73188 zgc:76990 zgc:77139 zgc:77369 zgc:77482 zgc:77621 zgc:77672 zgc:85830 zgc:86762 zgc:86820 zgc:86833 zgc:86851 zgc:86923 zgc:91842 zgc:92021 zgc:92282 zgc:92464 zgc:92596 zgc:92716 zgc:92726 zgc:92791 zom zombie	Danio rerio (zebrafish)
ABC-family proteins mediated transport	26S protease regulatory subunit 10B 26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11B 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 (Fragment) ABC-type glutathione-S-conjugate transporter ATP-binding cassette sub-family B member 9 ATP-binding cassette sub-family C member 5 ATP-binding cassette sub-family F member 1 Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator Derlin E3 ubiquitin-protein ligase RNF185 Endoplasmic reticulum lectin Endoplasmic reticulum lectin Erlin-1 Erlin-2 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Proteasome (Prosome, macropain) 26S subunit, ATPase, 1a Proteasome (Prosome, macropain) 26S subunit, ATPase, 1b Proteasome 20S subunit beta 11b Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4B Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-1 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A3KGZ4 A3KNN5 A3QK16 B0R1D0 B3DG31 E1B2R7 F1DB26 F1QGH9 F1QGW6 F1QK93 F1QR78 F1R2X6 H1ACM0 O57330 O57332 Q08C06 Q1LX78 Q3B7P7 Q4V918 Q4VBR8 Q4VBS8 Q58EG2 Q6AZC1 Q6DGX8 Q6DGY8 Q6DHI9 Q6DRD2 Q6DRF3 Q6IQ72 Q6IQC6 Q6IQD0 Q6IQH4 Q6NV15 Q6NY78 Q6NYV1 Q6P0I2 Q6PC78 Q6TGV5 Q6TGV6 Q7SXA3 Q7T3B1 Q7ZU20 Q7ZU69 Q7ZU99 Q7ZUJ8 Q7ZV77 Q7ZWD1 Q7ZWE5 Q7ZYX7 Q801W1 Q803G0 Q8AW07 Q8QFL6 Q9I9E9 Q9PTH5 Q9PUC4 Q9PUS3	CH211-265P12.8 LMP7 MRP PA28-gamma PSMA5 PSMB9A PSMD10 Psma2 Psmb11b Y abcb9 abcc2 abcc4 abcc5 abcf1 beta1 beta1ia beta2i beta5 beta5ia beta5tb cb1019 cdc48 cftr dZ52I16.4 derl2 eif2 eif2s1 eif2s1b eif2s2 eif2s3 erlec1 erlin1 erlin2 etID309919.2 fa93g07 fb17c09 fb19d01 fb20g04 fb49a10 fc34f08 fj42d12 fj51h02 fk89d05 gankyrin hm:zeh0386 ik:tdsubc_1f2 im:6909944 lmp2 lmp7 macropain os9 prosome psma1 psma2 psma2a psma2b psma3 psma4 psma5 psma6b psma7 psma8 psmb1 psmb10 psmb11b psmb12 psmb13a psmb2 psmb3 psmb5 psmb6 psmb8 psmb8a psmb9 psmb9a psmc1 psmc1a psmc1b psmc2 psmc4 psmc5 psmc6 psmd1 psmd10 psmd11b psmd12 psmd13 psmd14 psmd3 psmd4 psmd4a psmd6 psmd7 psmd8 psme1 psme2 psme3 psme4b rnf185 rps27a sb:cb309 si:busm1-52i16.4 si:ch1073-183g13.2 si:dkey-21k4.3 si:dz202l16.5 si:dz52i16.4 si:rp71-45k5.4 si:zc14a17.13 tdsubc_1f2 uba52 unp309 unp310 vcp wu:fa14g03 wu:fa66f04 wu:fa91f08 wu:fa93g07 wu:faa49c06 wu:fb05d04 wu:fb11d10 wu:fb17c09 wu:fb19c08 wu:fb19d01 wu:fb20g04 wu:fb23a11 wu:fb38a06 wu:fb49a10 wu:fb59c07 wu:fb79c06 wu:fb98h03 wu:fc26g03 wu:fc34f08 wu:fc39a05 wu:fc49f02 wu:fc85c10 wu:fe05d10 wu:fe38b10 wu:fi03c01 wu:fi15g10 wu:fj14c10 wu:fj22d05 wu:fj42d12 wu:fj51h02 wu:fj94a08 wu:fk28c01 wu:fk89d05 wu:fu10f07 wu:fu88b08 x xx:tdsubc_1f2 y zgc:109707 zgc:109823 zgc:110363 zgc:110436 zgc:110710 zgc:114044 zgc:123344 zgc:153838 zgc:162272 zgc:55284 zgc:55818 zgc:56176 zgc:56374 zgc:56377 zgc:56471 zgc:56516 zgc:63709 zgc:63995 zgc:65867 zgc:66072 zgc:66168 zgc:77084 zgc:77139 zgc:77369 zgc:77482 zgc:85667 zgc:86762 zgc:86820 zgc:86833 zgc:86851 zgc:86923 zgc:91842 zgc:92282 zgc:92464 zgc:92596 zgc:92716 zgc:92726 zgc:92791	Danio rerio (zebrafish)
Glycosphingolipid biosynthesis	2-hydroxyacylsphingosine 1-beta-galactosyltransferase precursor Beta-1,4 N-acetylgalactosaminyltransferase Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase Galactose-3-O-sulfotransferase 1a Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase A Lactosylceramide alpha-2,3-sialyltransferase ceramide glucosyltransferase	A0JMC3 A1L229 A2BGH3 Q1ECX6 Q3YL68 Q501W7 Q7T3S5 Q802Y5	B4GALNT1 b3gnt5 b3gnt5a b4galnt1a b4galt5 b4galt6 cb539 gal3st1 gal3st1a sb:cb539 si:dkey-189j19.2 si:dkeyp-86g2.2 st3Gal-V st3gal5 ugcg ugt8 wu:fc08a12 zgc:112506 zgc:158609 zgc:55730	Danio rerio (zebrafish)
MTOR signalling	14-3-3 protein beta/alpha-B GTP-binding protein Rheb Neutral amino acid transporter 9 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory-associated protein of MTOR, complex 1 Serine/threonine-protein kinase TOR Target of rapamycin complex subunit lst8 non-specific serine/threonine protein kinase	A0A0R4IFI0 E7EXT6 E7FA90 Q06RG6 Q08BA4 Q0P3X8 Q502N9 Q503S6 Q6DEG4 Q6PC18 Q7T356 Q7ZUI2 Q803V5	RRAGB akt3b frap1 gbl lamtor2 lamtor3 lamtor4 lamtor5 lst8 mapksp1 mlst8 mtor rheb rptor rraga rragc rragca si:dkey-176g4.2 slc38a9 tor wu:fc22h08 wu:fc68h09 ywhab ywhab2 ywhabb zgc:111971 zgc:56499 zgc:73144	Danio rerio (zebrafish)
mTORC1-mediated signalling	14-3-3 protein beta/alpha-B 40S ribosomal protein S6 Eukaryotic translation initiation factor 4E-1A Eukaryotic translation initiation factor 4E-binding protein 1 GTP-binding protein Rheb Neutral amino acid transporter 9 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory-associated protein of MTOR, complex 1 Ribosomal protein S6 kinase Serine/threonine-protein kinase TOR Target of rapamycin complex subunit lst8 peptidylprolyl isomerase	A0A0R4IFI0 E7FA90 Q06RG6 Q08BA4 Q0P3X8 Q502N9 Q503S6 Q6DEG4 Q6DHL6 Q6PBJ1 Q6PC18 Q6PFS8 Q7T356 Q7ZUI2 Q802Y7 Q803V5 Q9DFS6	RRAGB S6K1 eif4ea eif4ebp1 fc04h09 fc51h01 fkbp1b frap1 gbl lamtor2 lamtor3 lamtor4 lamtor5 lst8 mapksp1 mlst8 mtor rheb rps6 rps6kb1 rps6kb1b rptor rraga rragc rragca si:dkey-176g4.2 si:dkeyp-115a10.1 slc38a9 tor wu:fa92e06 wu:fb64g06 wu:fc04h09 wu:fc22h08 wu:fc51h01 wu:fc68h09 ywhab ywhab2 ywhabb zgc:111971 zgc:55713 zgc:56499 zgc:73144 zgc:73381	Danio rerio (zebrafish)
TP53 Regulates Metabolic Genes	14-3-3 protein beta/alpha-B 14-3-3 protein epsilon 14-3-3 protein eta 14-3-3 protein gamma-1 14-3-3 protein theta 14-3-3 protein theta 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit gamma-1 Acetyl-CoA carboxylase kinase COX11 homolog, cytochrome c oxidase assembly protein Cox7a2l protein Cytochrome c oxidase assembly protein COX14 homolog Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial Cytochrome c oxidase assembly protein COX19 Cytochrome c oxidase assembly protein COX20, mitochondrial Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 2 Cytochrome c oxidase subunit 3 Cytochrome c oxidase subunit 4 Cytochrome c oxidase subunit 5A, mitochondrial Cytochrome c oxidase subunit 5B, mitochondrial Cytochrome c oxidase subunit 7B, mitochondrial Cytochrome c oxidase subunit 7C, mitochondrial Cytochrome c oxidase subunit NDUFA4 Cytochrome c oxidase subunit Cytochrome c oxidase subunit Cytochrome c DNA damage-inducible transcript 4 protein GTP-binding protein Rheb Glucose-6-phosphate isomerase NADH dehydrogenase (Ubiquinone) 1 alpha subcomplex 4, like Neutral amino acid transporter 9 Peroxiredoxin-2 Peroxiredoxin-5 Probable fructose-2,6-bisphosphatase TIGAR A Protein SCO2 homolog, mitochondrial Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory-associated protein of MTOR, complex 1 SURF1-like protein Serine/threonine-protein kinase TOR Sestrin 2 Target of rapamycin complex subunit lst8 Thioredoxin Thioredoxin Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like isoform X1 glutaminase thioredoxin-dependent peroxiredoxin	A0A0R4IFI0 A0F081 A1L248 A2AWE1 A3KNN8 A5WUM0 A8E7D3 B3DJA6 B7ZVA6 E7F354 E7F6N5 E7FA90 Q06RG6 Q08BA4 Q0IJ39 Q0P3X8 Q29RA5 Q4VBU7 Q502C8 Q502N9 Q503S6 Q568H2 Q5RH02 Q642I9 Q6DEG4 Q6DGI6 Q6DGJ6 Q6DH63 Q6DH88 Q6DHM2 Q6IQM2 Q6IQU9 Q6P102 Q6PBH5 Q6PBP0 Q6PC18 Q6PCS7 Q6TNV0 Q7SXI1 Q7T346 Q7T356 Q7T3G2 Q7ZTT8 Q7ZUI2 Q7ZUI4 Q7ZUM0 Q7ZW20 Q803M8 Q803V5 Q9MIY4 Q9MIY7 Q9MIY8	COX4I1 D244 PGI RRAGB TXN cb116 cb58 coi coii coiii cox1 cox11 cox16 cox19 cox2 cox20 cox3 cox4i1 cox5a cox5aa cox5ba cox6a1 cox6b1 cox7a2l cox7a3 cox7b cox7c coxi coxii coxiii cyc ddit4 fa92g05 fam36a fb15h09 fb93e02 fe38c12 fk47c09 frap1 gbl glsl gpi gpib hm:zeh0438 hm:zehl0637 hm:zehn0976 im:6898613 im:6904550 im:7154392 lamtor2 lamtor3 lamtor4 lamtor5 lst8 mapksp1 mg:bb02d03 mlst8 mt-co1 mt-co2 mt-co3 mtco1 mtco2 mtco3 mtor ndufa4 ndufa4a ndufa4l ns:zf-e250 pgi-2 prdx1 prdx2 prdx5 prkaa1 prkab1a prkag1 rheb rptor rraga rragc rragca sb:cb130 sco2 sesn2 si:dkey-161j23.2 si:dkey-176g4.2 si:dkey-222f2.8 slc38a9 surf1 tigara tor txn wu:fa91b01 wu:fa92g05 wu:fa94c10 wu:fa94d09 wu:fb02e12 wu:fb15h09 wu:fb33b01 wu:fb36f06 wu:fb48f06 wu:fb51h04 wu:fb93e02 wu:fc22h08 wu:fc68h09 wu:fd12h04 wu:fe38c12 wu:fi22e10 wu:fj32b09 wu:fj35d07 wu:fj49c05 wu:fj56d06 wu:fk47c09 wu:fk86h02 wu:fp89f04 wu:fq19b09 ywhab ywhab2 ywhabb ywhabl ywhae ywhae1 ywhag ywhag2 ywhah ywhaq ywhaq1 ywhaq2 ywhaqa ywhaqb ywhaz zeh0438 zgc:103782 zgc:109989 zgc:110058 zgc:110300 zgc:110343 zgc:111971 zgc:112318 zgc:114165 zgc:158646 zgc:162286 zgc:55377 zgc:55499 zgc:56499 zgc:56564 zgc:63883 zgc:63896 zgc:66312 zgc:73065 zgc:73144 zgc:73316 zgc:77062 zgc:77351 zgc:92228 zgc:92631 zgc:92891 zgc:92903	Danio rerio (zebrafish)
The canonical retinoid cycle in rods (twilight vision)	11-cis retinol dehydrogenase isoform X1 Cellular retinaldehyde-binding protein b Cyp4v2 protein Dehydrogenase/reductase (SDR family) member 9 Lecithin retinol acyltransferase Rdh12 protein Retinoid isomerohydrolase Retinol binding protein 1b, cellular Retinol dehydrogenase 10-A Retinol dehydrogenase 1 Rhodopsin	A0JMQ6 A1L1W4 B0R174 F1Q7T8 F1RCW4 P35359 Q6DG78 Q6P027 Q6PBR3 Q6PBW5 Q7ZUX4	CRALBPb RDHA RDHB cyp4v2 cyp4v2a dhrs9 im:6901729 im:7136890 lrat lrata rbp1 rbp1.1 rbp1b rdh1 rdh10a rdh12 rdh1l rdh5 rho rlbp1 rlbp1b rpe65a rpepa sb:eu611 si:dkey-102c8.5 wu:fb64b07 wu:fd50b03 wu:fj43a10 zfo2 zgc:100825 zgc:154161 zgc:73286 zgc:77766 zgc:92430	Danio rerio (zebrafish)
Metabolism of folate and pterines	10-formyltetrahydrofolate dehydrogenase 5-formyltetrahydrofolate cyclo-ligase C-1-tetrahydrofolate synthase, cytoplasmic Folate receptor gamma precursor Folate transporter 1 Folylpolyglutamate synthase Mitochondrial folate transporter/carrier Proton-coupled folate transporter Serine hydroxymethyltransferase dihydrofolate reductase formate--tetrahydrofolate ligase glycine hydroxymethyltransferase methenyltetrahydrofolate cyclohydrolase methylenetetrahydrofolate reductase (NADPH)	A0A0G2L0J2 A5PLB2 A9LDD9 B0V153 E3NZ06 E7F2A7 F1Q7N0 F1QQ79 Q5CZP1 Q5RIH2 Q6GMK2 Q6IQS4 Q7SXN1 Q7ZWG6	aldh1l1 cb595 dhfr fa92h12 fk48e08 fk51d09 folr fpgs im:7144504 mthfd1a mthfd1l mthfd2 mthfr mthfs pcft shmt1 shmt2 si:dkey-25e12.5 si:dkey-25e12.6 si:dkeyp-100a1.4 slc19a1 slc25a32b slc46a1 wu:fa92h12 wu:fb38b11 wu:fe12e11 wu:fk48e08 wu:fk49h03 wu:fk51d09 zgc:110786 zgc:63807 zgc:66171 zgc:77524 zgc:86637 zgc:91891	Danio rerio (zebrafish)
RHOG GTPase cycle	10 kDa heat shock protein, mitochondrial isoform 1 ADP-ribosylation factor GTPase-activating protein 3 Arhgap1 protein Caveolin Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein 1 homolog Dedicator of cytokinesis 1 Dedicator of cytokinesis 5 Desmoglein-2.1 Integrin beta Integrin beta Integrin beta MAGUK p55 subfamily member 7 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial Phosphatidylinositol 3-kinase regulatory subunit alpha RAB7, member RAS oncogene family Ras homolog family member Gb Rho GDP dissociation inhibitor (GDI) gamma Rho GDP-dissociation inhibitor 1 Rho GTPase-activating protein 35 Rho GTPase-activating protein 5 Transferrin receptor protein 1 Triple functional domain protein Vang-like protein Vesicle-associated membrane protein 3 glycine hydroxymethyltransferase non-specific serine/threonine protein kinase receptor protein-tyrosine kinase	A8E1V6 A8E1V7 A9LDD9 B0S6V7 B0V210 B3DIV2 E7F8G5 F1R372 H2EQR6 Q19U09 Q1LUA6 Q3YAA0 Q52WY2 Q566S4 Q568D8 Q5MPX4 Q6DG42 Q6IQI7 Q6IQK3 Q6NZS1 Q6P0D7 Q6TNW0 Q6YLH9 Q7SZQ6 Q7T2C6 Q802W6 Q803F2 Q90YM8	ARFGAP3 ARHG ARHGDIB CAV1 LOC100004299 arfgap3 arhgap1 arhgap35a arhgap5 arhgdia arhgdig cav1 cb422 cb810 cdc42 cdc42a cpn10 cyfip1 dlg3 dock1 dock5 dsg2 dsg2.1 dsga epha2 epha2a fj62g06 fk03b12 fk61c06 hmp hspe1 id:ibd5152 itgb1 itgb1b itgb1b.1 itgb1b.2 kinase mpp7 ndufs3 pak2 pak2a pik3r1 rab-7 rab7 rab7a rhog rhogb rtk6 shmt2 si:dz198m22.1 stb2 tfr1a trio vamp3 vangl1 wu:cegs2891 wu:fa96g11 wu:fb07d08 wu:fb65b05 wu:fb71h01 wu:fc07c04 wu:fj62g06 wu:fk03b12 wu:fk30f01 wu:fk61c06 zgc:110361 zgc:112520 zgc:55554 zgc:55848 zgc:63918 zgc:64058 zgc:65966 zgc:77681 zgc:85632 zgc:85765 zgc:86726 zgc:86747 zgc:91798	Danio rerio (zebrafish)
Phospholipase C-mediated cascade: FGFR1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Klotho Putative fibroblast growth factor 1	B3DGE3 F1RC43 O57341 P48802 Q1XG76 Q38PL0 Q5MK87 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q804J6 Q8AY90 Q90Z00 Q9DFC9	dob fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a fj46f04 id:ibd5158 kl plcg1 si:dkey-21e2.2 si:dkeyp-74c5.3 wu:fb05c08 wu:fc89b01 wu:fd11d03 wu:fj46f04 wu:fj57a05 zgc:109774 zgc:194535	Danio rerio (zebrafish)
Phospholipase C-mediated cascade; FGFR4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 O57341 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE1 Q6PBT8 Q6SJP8 Q804J6 Q90413 Q9DFC9	dob fc89b01 fgf-1 fgf-8 fgf1 fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf23 fgf4 fgf6b fgf8 fgf8a fgfr4 fj46f04 id:ibd5158 plcg1 wu:fb05c08 wu:fc89b01 wu:fj46f04 wu:fj57a05 zgc:194535	Danio rerio (zebrafish)
Phospholipase C-mediated cascade; FGFR3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 O57341 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE2 Q6PBT8 Q6SJP8 Q804J6 Q9DFC9 Q9I8X3	dob fc89b01 fgf-1 fgf-8 fgf1 fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf23 fgf4 fgf5 fgf8 fgf8a fgfr3 fj46f04 id:ibd5158 plcg1 wu:fb05c08 wu:fc89b01 wu:fj46f04 wu:fj57a05	Danio rerio (zebrafish)
Phospholipase C-mediated cascade; FGFR2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 B3DHR9 O57341 P48802 Q1XG76 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q804J6 Q8AY90 Q8JG38 Q9DFC9	dob fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf7 fgf8 fgf8a fgfr2 fj46f04 id:ibd5158 plcg1 si:dkey-21e2.2 si:dkeyp-74c5.3 wu:fb05c08 wu:fc89b01 wu:fd11d03 wu:fj46f04 wu:fj57a05 zgc:109774 zgc:194535	Danio rerio (zebrafish)
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Adapter molecule crk Crk-like protein Cytoplasmic protein Cytoplasmic protein GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 2a Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Platelet-derived growth factor receptor alpha Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Proto-oncogene tyrosine-protein kinase Src Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Son of sevenless homolog phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A2R8Q0D8 A2RRV5 B0S6V7 B3DGV1 B3DHG9 E7F251 E7F6M0 F1QAD7 O93598 P79737 Q08CD2 Q1JPZ3 Q4V9A1 Q503B6 Q5RKN6 Q68SP2 Q68SP3 Q6DEM2 Q6PC73 Q6PH06 Q804J6 Q9DE49	Stat5 crk crkl fb18e12 fb34h10 fc05a01 fd20h08 fi19g05 fj46f04 fj59e07 grb2 grb2a grb2b hrasb hrasl im:7147817 nck1b nck2b nras pdgfab pdgfbb pdgfra pik3ca pik3cb pik3r1 pik3r2 plcg1 sb:eu508 sb:eu615 si:ch211-147g19.3 sos1 src stat1 stat1a stat5 stat5.1 stat5.2 stat5a stat5b stat6 stat7 wu:fa55g05 wu:fb18e12 wu:fb34e06 wu:fb34h10 wu:fb65b05 wu:fc05a01 wu:fc32c12 wu:fc54a04 wu:fd20h08 wu:fi19g05 wu:fj46f04 wu:fj57a05 wu:fj59e07 wu:fj60e01 wu:fj66g07 zgc:100936 zgc:103549 zgc:110734 zgc:153249 zgc:158274 zgc:63469 zgc:73077 zgc:92024	Danio rerio (zebrafish)
Signaling by ALK	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma ALK and LTK ligand 1 ALK and LTK ligand 2b ALK tyrosine kinase receptor Midkine Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Pleiotrophin phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	B0S6V7 B3DHG9 E7F251 E7FAP8 F1QAD7 F8W2C9 F8W3R9 Q502U6 Q804J6 Q9DDG2	alk alkal1 alkal2b cb518 fb79b05 fj33b02 fj46f04 fj48a12 mdk mdk2 mdkb pik3ca pik3cb pik3r1 pik3r2 plcg1 plei2 ptn wu:fb65b05 wu:fb79b05 wu:fj33b02 wu:fj46f04 wu:fj48a12 wu:fj57a05 zHBNF zgc:111787	Danio rerio (zebrafish)
VEGFR2 mediated cell proliferation	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 3-phosphoinositide-dependent protein kinase 1 Protein kinase C beta type Protein kinase C delta type Proto-oncogene tyrosine-protein kinase Src Vascular endothelial growth factor A-A Vascular endothelial growth factor receptor 2	O73682 Q1JPZ3 Q5GIT4 Q6NZV1 Q7SY24 Q7ZUC5 Q804J6	fb09d10 fj46f04 flk1b fv43b11 kdr kdrb pdpk1b plcg1 prkcb1 prkcbb prkcd prkcda src vegf vegfa vegfaa wu:fb09d10 wu:fj46f04 wu:fj57a05 wu:fv43b11 zgc:56558 zgc:77318	Danio rerio (zebrafish)
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Inositol-tetrakisphosphate 1-kinase Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A Phosphoinositide phospholipase C	A5D6R3 A7MD68 Q2I6J1 Q7ZZ56 Q804J6 X1WEB0	fa11a08 fb73f10 fc83f12 fd16b10 fj46f04 fk90e11 inppl1a itpk1b plcd1a plcd3a plcg1 pten ptenb ship2a si:bz1g13.4 wu:fa11a08 wu:fb73f10 wu:fc83f12 wu:fd16b10 wu:fj46f04 wu:fj57a05 wu:fk90e11 zgc:165641	Danio rerio (zebrafish)

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