GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **228** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Deadenylation of mRNA	ATP-dependent RNA helicase FAL1 ATP-dependent RNA helicase eIF4A Eukaryotic initiation factor 4F subunit p150 Eukaryotic translation initiation factor 4B Eukaryotic translation initiation factor 4E Nucleolar protein 13 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 PAN2-PAN3 deadenylation complex subunit PAN3 Protein PES4	P07260 P10081 P34167 P36102 P39684 P39935 P53010 P53883 Q12099	CDC33 ECM35 FAL1 NOP13 PAN2 PAN3 PES4 STM1 TIF1 TIF2 TIF3 TIF41A TIF41B TIF42 TIF45 TIF4631	Saccharomyces cerevisiae (brewer's yeast)
Dectin-1 mediated noncanonical NF-kB signaling	Serine/threonine-protein kinase BCK1/SLK1/SSP31	Q01389	BCK1 LAS3 SLK1 SSP31	Saccharomyces cerevisiae (brewer's yeast)
Detoxification of Reactive Oxygen Species	Cytochrome c isoform 1 Cytochrome c isoform 2 Glutathione reductase Peroxiredoxin AHP1 Peroxiredoxin TSA1 Peroxiredoxin TSA2 Peroxisomal catalase A Probable ferric reductase transmembrane component 8 Probable metalloreductase AIM14 Superoxide dismutase 1 copper chaperone Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn], mitochondrial Thioredoxin-1 Thioredoxin-2 Thioredoxin-3, mitochondrial	P00044 P00045 P00445 P00447 P15202 P22217 P22803 P25372 P34760 P38013 P40202 P41921 P53109 Q04120 Q12209	AHP1 AIM14 CCS1 CTA1 CYC1 CYC7 CYP3 FRE8 GLR1 LYS7 SOD1 SOD2 TPX1 TRX1 TRX2 TRX3 TSA TSA1 TSA2 ZRG14	Saccharomyces cerevisiae (brewer's yeast)
Digestion of dietary carbohydrate	Sporulation-specific chitinase 2	Q06350	CTS2	Saccharomyces cerevisiae (brewer's yeast)	G80384UV
E3 ubiquitin ligases ubiquitinate target proteins	Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal targeting signal receptor Peroxisome assembly protein 12 Peroxisome biogenesis factor 10 Polyubiquitin Postreplication repair E3 ubiquitin-protein ligase RAD18 Proliferating cell nuclear antigen Ubiquitin-conjugating enzyme E2 13 Ubiquitin-conjugating enzyme E2 2 Ubiquitin-conjugating enzyme E2 4 Ubiquitin-conjugating enzyme E2-16 kDa Ubiquitin-conjugating enzyme variant MMS2 Uncharacterized ATP-dependent helicase IRC20	P06104 P0CG63 P10862 P15731 P15732 P15873 P35056 P52490 P53112 P53152 P80667 Q04370 Q05568 Q06554	IRC20 MMS2 PAS10 PAS20 PAS4 PEX10 PEX12 PEX13 PEX14 PEX5 POL30 RAD18 RAD6 SCD2 UBC13 UBC2 UBC4 UBC5 UBI4	Saccharomyces cerevisiae (brewer's yeast)
Energy dependent regulation of mTOR by LKB1-AMPK	5'-AMP-activated protein kinase subunit gamma Carbon catabolite-derepressing protein kinase Cruciform DNA-recognizing protein 1 Fatty acyl-CoA synthetase and RNA processing-associated kinase 1 SNF1 protein kinase subunit beta-1 SNF1 protein kinase subunit beta-2 SNF1 protein kinase subunit beta-3 Serine/threonine protein kinase KIN1 Serine/threonine-protein kinase KIN2 Serine/threonine-protein kinase KIN4 Signal transduction protein MDG1	P06782 P12904 P13185 P13186 P32578 P34164 P38845 P53885 Q01919 Q03002 Q04739	CAT1 CAT3 CCR1 CRP1 FRK1 GAL83 GLC2 KIN1 KIN2 KIN3 KIN31 KIN4 MDG1 PAS14 SCI1 SIP1 SIP2 SNF1 SNF4 SPM1 SPM2	Saccharomyces cerevisiae (brewer's yeast)
Estrogen-dependent gene expression	ATP-dependent RNA helicase DBP2 CTD kinase subunit alpha CTD kinase subunit beta DNA damage-responsive transcriptional repressor RPH1 DNA-directed RNA polymerase II subunit RPB11 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Fork head protein homolog 1 Forkhead transcription factor HCM1 Histone H2A.1 Histone H2A.2 Histone H2A.Z Histone H2B.1 Histone H2B.2 Histone H3-like centromeric protein CSE4 Histone H3 Histone H4 Histone acetyltransferase ESA1 Histone acetyltransferase GCN5 Histone deacetylase RPD3 Nitrogen regulatory protein DAL80 Nitrogen regulatory protein GLN3 Polyamine oxidase FMS1 Protein BUR2 Protein GZF3 Protein arginine N-methyltransferase 1 TATA-box-binding protein Transcription initiation factor IIA large subunit Transcription initiation factor IIA subunit 2 Transcription initiation factor IIF subunit alpha Transcription initiation factor IIF subunit beta Transcriptional activator/repressor GIS1 Transcriptional regulator NRG1 Transcriptional regulatory protein GAT1	P02293 P02294 P02309 P04050 P04911 P04912 P08518 P13393 P16370 P18494 P20433 P20434 P20435 P20436 P22139 P24783 P25364 P26343 P27999 P32561 P32773 P32774 P34087 P36012 P38074 P38902 P39956 P40422 P40466 P41895 P41896 P42944 P43574 P46962 P50264 P61830 Q03125 Q03330 Q03833 Q03957 Q05949 Q08649 Q12692	ADA4 BTF1 BUR2 CSE4 CSL2 CST4 CTK1 CTK2 DAL80 DBP2 ESA1 FKH1 FMS1 GAT1 GCN5 GIS1 GLN3 GZF3 H2A1 H2A2 H2AZ H2B1 H2B2 HCM1 HHF1 HHF2 HHT1 HHT2 HMT1 HTA1 HTA2 HTA3 HTB1 HTB2 HTZ1 MOF6 MSS1 NRG1 ODP1 REC3 RMT1 RPA7 RPB1 RPB10 RPB11 RPB12 RPB150 RPB2 RPB220 RPB3 RPB4 RPB5 RPB6 RPB7 RPB8 RPB9 RPC10 RPC9 RPD3 RPH1 RPO21 RPO22 RPO26 SDI2 SDS6 SIN2 SPT11 SPT12 SPT15 SSU71 SUA8 SWI9 TBP1 TFG1 TFG2 TOA1 TOA2 UGA43	Saccharomyces cerevisiae (brewer's yeast)
Eukaryotic Translation Termination	Eukaryotic peptide chain release factor GTP-binding subunit Eukaryotic peptide chain release factor subunit 1 Multifunctional methyltransferase subunit TRM112 eRF1 methyltransferase catalytic subunit MTQ2	P05453 P12385 P53738 Q03920	GST1 MTC6 MTQ2 PNM2 SAL3 SAL4 SUF12 SUP1 SUP2 SUP35 SUP45 TRM112	Saccharomyces cerevisiae (brewer's yeast)
Fatty acyl-CoA biosynthesis	3-oxoacyl-[acyl-carrier-protein] reductase Acetyl-CoA carboxylase Acyl-CoA desaturase 1 Very long-chain fatty acid transport protein	P21147 P35731 P38225 Q00955	ABP2 ACC1 FAS3 FAT1 MTR7 OAR1 OLE1	Saccharomyces cerevisiae (brewer's yeast)
Formation of the Early Elongation Complex	Cyclin CCL1 DNA-directed RNA polymerase II subunit RPB11 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD/RAD3 General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2 General transcription and DNA repair factor IIH subunit SSL1 General transcription and DNA repair factor IIH subunit TFB1 General transcription and DNA repair factor IIH subunit TFB2 General transcription and DNA repair factor IIH subunit TFB4 General transcription and DNA repair factor IIH subunit TFB5 Nuclear cap-binding protein complex subunit 1 Nuclear cap-binding protein subunit 2 RNA polymerase II subunit A C-terminal domain phosphatase RNA polymerase II transcription factor B subunit 3 Serine/threonine-protein kinase KIN28 Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription initiation factor IIF subunit alpha Transcription initiation factor IIF subunit beta	P04050 P06242 P06839 P08518 P16370 P20433 P20434 P20435 P20436 P22139 P27692 P27999 P32776 P32914 P34087 P34160 P37366 P38902 P40422 P41895 P41896 Q00578 Q02939 Q03254 Q03290 Q04673 Q08920 Q12004 Q3E7C1	CBC1 CBC2 CBP20 CBP80 CCL1 FCP1 GCR3 KIN28 LOM3 MUD13 RAD25 RAD3 REM1 RIG2 RPA7 RPB1 RPB10 RPB11 RPB12 RPB150 RPB2 RPB220 RPB3 RPB4 RPB5 RPB6 RPB7 RPB8 RPB9 RPC10 RPC9 RPO21 RPO22 RPO26 SAE1 SPT4 SPT5 SSL1 SSL2 SSU71 STO1 SUA8 SUT1 TFB1 TFB2 TFB3 TFB4 TFB5 TFG1 TFG2 UVS112	Saccharomyces cerevisiae (brewer's yeast)
Formation of the active cofactor, UDP-glucuronate	UTP--glucose-1-phosphate uridylyltransferase	P32861	UGP1	Saccharomyces cerevisiae (brewer's yeast)
Fructose biosynthesis	D-arabinose dehydrogenase [NAD(P)+] heavy chain Sorbitol dehydrogenase 1 Sorbitol dehydrogenase 2	P35497 P38115 Q07786	ARA1 SDH1 SOR1 SOR2	Saccharomyces cerevisiae (brewer's yeast)	G58161NS
G alpha (12/13) signalling events	Actin cytoskeleton-regulatory complex protein END3 Actin cytoskeleton-regulatory complex protein PAN1 EH domain-containing and endocytosis protein 1 GTP-binding protein RHO1 GTP-binding protein RHO2 GTP-binding protein RHO3 GTP-binding protein RHO4 Guanine nucleotide-binding protein alpha-1 subunit Increased rDNA silencing protein 4 Nuclear fusion protein FUS2	P06780 P06781 P08539 P32521 P34216 P36115 P39013 Q00245 Q00246 Q05670	BUD15 CDC70 DAC1 DIM2 EDE1 END3 FUS2 GPA1 IRS4 MDP3 MIP3 PAN1 RHO1 RHO2 RHO3 RHO4 SCG1	Saccharomyces cerevisiae (brewer's yeast)
G alpha (i) signalling events	Guanine nucleotide-binding protein alpha-2 subunit Protein SST2 Regulator of G-protein signaling 2	P10823 P11972 Q99188	GPA2 RGS2 SSP101 SST2	Saccharomyces cerevisiae (brewer's yeast)
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	Bud site selection protein 5 Cell division control protein 25 Guanine nucleotide exchange factor LTE1 Ras-related protein RSR1	P04821 P07866 P13856 P25300	BUD1 BUD5 CDC25 CTN1 EIS4 LTE1 MSI2 RSR1	Saccharomyces cerevisiae (brewer's yeast)
Glutathione conjugation	D-arabinose dehydrogenase [NAD(P)+] heavy chain NADPH-dependent alpha-keto amide reductase S-formylglutathione hydrolase Uncharacterized oxidoreductase YJR096W	P38115 P40363 P47137 Q07551	ARA1 YDL124W YJL068C YJR096W	Saccharomyces cerevisiae (brewer's yeast)
Glutathione synthesis and recycling	5-oxoprolinase Cys-Gly metallodipeptidase DUG1 Glutathione hydrolase proenzyme Glutathione synthetase GSH2 Glutathione-specific gamma-glutamylcyclotransferase	P28273 P32656 P43616 Q05902 Q08220	CIS2 DUG1 ECM38 GCG1 GSH2 OXP1	Saccharomyces cerevisiae (brewer's yeast)
Glycerophospholipid biosynthesis	Mitochondrial import inner membrane translocase subunit TIM54 Sphingoid long chain base kinase 4 Sphingoid long chain base kinase 5	P47045 Q06147 Q12246	LCB4 LCB5 TIM54	Saccharomyces cerevisiae (brewer's yeast)
Glycerophospholipid catabolism	Ectonucleotide pyrophosphatase/phosphodiesterase 1 Ectonucleotide pyrophosphatase/phosphodiesterase 2 Lysophospholipase NTE1	P25353 P39997 Q04958	NPP1 NPP2 NTE1	Saccharomyces cerevisiae (brewer's yeast)
Glycogen breakdown (glycogenolysis)	Glycogen debranching enzyme Glycogen phosphorylase Glycogenin-1 Glycogenin-2 IME2-dependent-signaling protein Phosphoglucomutase 1 Phosphoglucomutase 2	P06738 P33401 P36143 P37012 P46958 P47011 Q06625	GA-5 GAL5 GDB1 GLG1 GLG2 GPH1 IDS2 PGM1 PGM2	Saccharomyces cerevisiae (brewer's yeast)	G58161NS
Glycogen synthesis	1,4-alpha-glucan-branching enzyme GLC7-interacting protein 2 GSY2-interacting protein PIG2 Glycogen [starch] synthase isoform 1 Glycogen [starch] synthase isoform 2 Glycogenin-1 Glycogenin-2 IME2-dependent-signaling protein Phosphoglucomutase 1 Phosphoglucomutase 2 Serine/threonine-protein phosphatase 1 regulatory subunit GAC1 Serine/threonine-protein phosphatase 1 regulatory subunit PIG1 UTP--glucose-1-phosphate uridylyltransferase	P23337 P27472 P28006 P32775 P32861 P33401 P36143 P37012 P40036 P40187 P46958 P47011 Q06216	GA-5 GAC1 GAL5 GIP2 GLC3 GLG1 GLG2 GSY1 GSY2 IDS2 PGM1 PGM2 PIG1 PIG2 UGP1	Saccharomyces cerevisiae (brewer's yeast)
Glycolysis	ATP-dependent 6-phosphofructokinase subunit alpha ATP-dependent 6-phosphofructokinase subunit beta Enolase 1 Enolase 2 Enolase-related protein 1 Enolase-related protein 2 Enolase-related protein 3 Glucokinase-1 Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase 1 Glyceraldehyde-3-phosphate dehydrogenase 2 Glyceraldehyde-3-phosphate dehydrogenase 3 Hexokinase-1 Hexokinase-2 N-acetylglucosamine kinase Phosphoglycerate kinase Phosphoribomutase Putative glucokinase-2 Pyruvate kinase 1 Pyruvate kinase 2 Triosephosphate isomerase	P00358 P00359 P00360 P00549 P00560 P00924 P00925 P00942 P04806 P04807 P0CX10 P0CX11 P12709 P16861 P16862 P17709 P42222 P52489 Q03262 Q04409 Q06204	CDC19 EMI2 ENO1 ENO2 ENOA ENOB ERR1 ERR2 ERR3 GLK1 GPD1 GPD2 GPD3 HEX1 HKA HKB HOR3 HSP48 HXK1 HXK2 NGK1 PFK1 PFK2 PGI1 PGK1 PGM3 PRM15 PYK1 PYK2 SSS2 TDH1 TDH2 TDH3 TPI1	Saccharomyces cerevisiae (brewer's yeast)	G58161NS
Glycosphingolipid catabolism	Ectonucleotide pyrophosphatase/phosphodiesterase 1 Ectonucleotide pyrophosphatase/phosphodiesterase 2 Inositol phosphosphingolipids phospholipase C	P25353 P39997 P40015	ISC1 NPP1 NPP2	Saccharomyces cerevisiae (brewer's yeast)
Golgi Cisternae Pericentriolar Stack Reorganization	Cell cycle serine/threonine-protein kinase CDC5/MSD2 GRASP65 homolog protein 1 GTP-binding protein YPT11 GTP-binding protein YPT1	P01123 P32562 P48559 Q04410	CDC5 GRH1 MSD2 PKX2 YP2 YPT1 YPT11	Saccharomyces cerevisiae (brewer's yeast)
HATs acetylate histones	ATF/CREB activator 1 ATF/CREB activator 2 CRE-binding bZIP protein SKO1 Histone H2B.1 Histone H2B.2 Histone H4 Histone acetyltransferase type B catalytic subunit Histone acetyltransferase type B subunit 2	P02293 P02294 P02309 P39970 P39984 P40535 Q02100 Q12341	ACA1 ACA2 ACR1 CST6 H2B1 H2B2 HAT1 HAT2 HHF1 HHF2 HTB1 HTB2 SKO1 SPT12	Saccharomyces cerevisiae (brewer's yeast)

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