GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source Last Updated
Reactome March 20, 2024
ECODAB April 1, 2019
Displaying entries 226 - 250 of 360 in total
Pathway Name Protein Name UniProt ID Gene Symbol ▲ Organism GlyTouCan ID
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
  • CD26
  • DPP4
  • FFAR4
  • GCG
  • GNB1
  • GNB3
  • GPR119
  • GPR120
  • GRP
  • LEP
  • O3FAR1
  • OB
  • OBS
Sus scrofa (pig)
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
  • CD26
  • DPP4
  • GIP
  • GPR119
Sus scrofa (pig)
TNFs bind their physiological receptors
  • CD27
  • CD70
  • EDA
  • EDAR
  • EDARADD
  • LTA
  • TNFB
  • TNFRSF11B
  • TNFRSF13B
  • TNFRSF17
  • TNFRSF18
  • TNFRSF1A
  • TNFRSF1B
  • TNFRSF25
  • TNFRSF4
  • TNFRSF9
  • TNFSF1
  • TNFSF11
  • TNFSF13
  • TNFSF13B
  • TNFSF15
  • TNFSF18
  • TNFSF4
  • TNFSF9
Sus scrofa (pig)
Other interleukin signaling
  • CD4
  • CSF1
  • CSF1R
  • CSF3
  • CSF3R
  • IFNLR1
  • IL10RB
  • IL16
  • IL29
  • IL34
  • JAK1
  • PTPRZ1
  • SDC1
  • STX1A
  • STX3
  • STX4
  • STXBP2
  • TXLNA
  • TYK2
  • VAMP2
Sus scrofa (pig)
Hyaluronan uptake and degradation
  • CD44
  • GUSB
  • HEXA
  • HEXB
  • HMMR
  • HYAL1
  • HYAL2
  • LYVE1
  • SLC9A1
  • STAB2
Sus scrofa (pig)
Signal regulatory protein family interactions
  • CD47
  • DAP12
  • FYB1
  • GRB2
  • LOC100736623
  • LOC100739707
  • LOC102161654
  • PTK2B
  • SIRPA
  • SKAP2
  • TYROBP
Sus scrofa (pig)
Apoptotic cleavage of cell adhesion proteins
  • CDH1
  • CTNNB1
  • DSG1
  • DSG2
  • DSG3
  • DSP
  • OCLN
  • PKP1
  • TJP1
  • TJP2
Sus scrofa (pig)
Formation of the cornified envelope
  • CDSN
  • CELA2A
  • DSC1
  • DSC2
  • DSC3
  • DSG1
  • DSG2
  • DSG3
  • DSG4
  • DSP
  • ELA2
  • ELA2A
  • EVPL
  • JUP
  • Jup
  • KAZN
  • KLK12
  • KLK14
  • KLK5
  • LOC396866
  • PERP
  • PKP1
  • PKP2
  • PKP3
  • PKP4
  • PPL
  • RPTN
  • SPINK5
  • SPINK9
  • TCHH
  • TGM1
Sus scrofa (pig)
Reactions specific to the complex N-glycan synthesis pathway
  • CGA
  • CHST10
  • CHST8
  • FUCA1
  • FUT8
  • LHB
  • LOC100513844
  • MAN2A1
  • MAN2A2
  • MGAT2
Sus scrofa (pig)
Thyroxine biosynthesis
  • CGA
  • DUOX1
  • DUOX2
  • IYD
  • SLC5A5
  • TPO
  • TSHB
Sus scrofa (pig)
Hormone ligand-binding receptors
  • CGA
  • FSHB
  • FSHR
  • GNRH
  • GNRH1
  • GNRH2
  • GNRHR
  • GNRHR2
  • LHB
  • LHCGR
  • TSHB
  • TSHR
Sus scrofa (pig)
Glycoprotein hormones
  • CGA
  • FSHB
  • INHA
  • INHBA
  • INHBB
  • INHBC
  • INHBE
  • LHB
  • TSHB
Sus scrofa (pig)
Muscarinic acetylcholine receptors
  • CHRM1
  • CHRM2
  • CHRM3
  • CHRM4
  • CHRM5
Sus scrofa (pig)
Interleukin-1 signaling
  • CHUK
  • CUL1
  • IKBA
  • IKBKB
  • IKBKG
  • IL1A
  • IL1B
  • IL1B2
  • IL1R1
  • IL1R2
  • IRAK1
  • IRAK2
  • IRAK3
  • IRAK4
  • LMP2
  • LOC110255300
  • LOC110258125
  • LOC110258578
  • LOC110259156
  • MAP2K6
  • MAP3K3
  • MAP3K7
  • MYD88
  • NFKB1
  • NFKBIA
  • PELI2
  • PELI3
  • PRORP
  • PSMA1
  • PSMA2
  • PSMA4
  • PSMA5
  • PSMA6
  • PSMA7
  • PSMA8
  • PSMB1
  • PSMB10
  • PSMB11
  • PSMB3
  • PSMB7
  • PSMB9
  • PSMC1
  • PSMC3
  • PSMC5
  • PSMC6
  • PSMD1
  • PSMD11
  • PSMD13
  • PSMD14
  • PSMD2
  • PSMD3
  • PSMD4
  • PSMD6
  • PSMD7
  • PSMD8
  • PSMD9
  • PSME1
  • PSME2
  • PSME3
  • PSME4
  • PSMF1
  • RBX1
  • RELA
  • RPS27A
  • SKP1
  • SQSTM1
  • TAB1
  • TAB2
  • TAB3
  • TAK1b
  • TOLLIP
  • TRAF6
  • UBA52
  • UBB
  • UBC
  • UBE2NL
Sus scrofa (pig)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
  • CILP
  • IGF1
  • IGF1R
  • IGF2
Sus scrofa (pig)
Sialic acid metabolism
  • CMAS
  • CTSA
  • GLB1
  • GNE
  • NANP
  • NANS
  • NEU1
  • NEU2
  • NEU3
  • NEU4
  • NPL
  • SLC17A5
  • SLC35A1
  • ST3GAL-III
  • ST3GAL1
  • ST3GAL2
  • ST3GAL3
  • ST3GAL4
  • ST3GAL5
  • ST3GAL6
  • ST6GAL1
  • ST6GAL2
  • ST6GALNAC1
  • ST6GALNAC2
  • ST6GALNAC3
  • ST6GALNAC4
  • ST6GALNAC5
  • ST6GALNAC6
  • ST8SIA1
  • ST8SIA2
  • ST8SIA3
  • ST8SIA4
  • ST8SIA5
  • ST8SIA6
  • ST8Sia 2
Sus scrofa (pig)
Class A/1 (Rhodopsin-like receptors)
  • CMLKR1
  • CNR1
  • CNR2
  • GPBAR1
  • GPR132
  • GPR18
  • GPR183
  • GPR35
  • GPR39
  • GPR55
  • GPR68
  • HCAR2
  • MTNR1A
  • MTNR1B
  • PTAFR
  • SUCNR1
Sus scrofa (pig)
Activation of the phototransduction cascade
  • CNGA1
  • CNGB1
  • GNB1
  • PDE6A
  • PDE6G
  • RHO
  • RHO1
Sus scrofa (pig)
Trafficking and processing of endosomal TLR
  • CNPY3
  • CTSB
  • CTSK
  • CTSL
  • CTSL1
  • HSP90B1
  • LGMN
  • TLR7
  • TLR8
  • TLR9
  • TNRC5
  • UNC93B1
Sus scrofa (pig)
Collagen degradation
  • COL12A1
  • COL13A1
  • COL15A1
  • COL18A1
  • COL19A1
  • COL25A1
  • CTSB
  • CTSD
  • CTSK
  • CTSL
  • FURIN
  • MMP1
  • MMP11
  • MMP12
  • MMP13
  • MMP15
  • MMP20
  • MMP3
  • MMP7
  • MMP8
  • MMP9
  • PHYKPL
  • PRSS2
  • TMPRSS6
  • try
Sus scrofa (pig)
Activation of Matrix Metalloproteinases
  • COL18A1
  • CTSK
  • CTSL
  • CTSL1
  • FURIN
  • KLK1
  • LOC100154047
  • MMP1
  • MMP11
  • MMP13
  • MMP15
  • MMP16
  • MMP17
  • MMP24
  • MMP25
  • MMP3
  • MMP7
  • MMP8
  • MMP9
  • PLG
  • PRSS2
  • SPOCK3
  • TIMP1
  • TIMP2
  • try
Sus scrofa (pig)
Signaling by PDGF
  • COL4A1
  • COL4A2
  • COL4A3
  • COL4A4
  • COL4A5
  • COL6A1
  • COL6A2
  • COL6A3
  • COL6A5
  • COL6A6
  • COL9A1
  • COL9A2
  • COL9A3
  • FURIN
  • OPN
  • PDGFA
  • PDGFB
  • PDGFC
  • PDGFD
  • PDGFRA
  • PDGFRB
  • PLAT
  • PLG
  • PTPN12
  • SPP1
  • THBS1
  • THBS2
  • THBS3
  • THBS4
Sus scrofa (pig)
Lectin pathway of complement activation
  • COLEC10
  • COLEC11
  • FCN1
  • FCN2
  • MASP1
  • MASP2
  • MBL2
Sus scrofa (pig)
MET activates RAP1 and RAC1
  • CRK
  • DOCK7
  • GAB1
  • GRB2
  • HGF
  • MET
  • RAC1
  • RAP1B
  • RAPGEF1
Sus scrofa (pig)
Interleukin receptor SHC signaling
  • CSF2
  • CSF2RA
  • CSF2RB
  • GAB2
  • GRB2
  • IL2
  • IL2RA
  • IL2RB
  • IL2RG
  • IL5
  • IL5RA
  • INPP5D
  • INPPL1
  • JAK1
  • JAK2
  • JAK3
  • PIK3CA
  • PIK3CB
  • PIK3CD
  • PIK3R1
  • PIK3R2
  • SHC1
  • SOS1
Sus scrofa (pig)

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024