GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **276 - 300** of **360** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Inhibition of TSC complex formation by PKB	TSC complex subunit 1 TSC complex subunit 2 non-specific serine/threonine protein kinase	A0A287AQP0 A0A287BG63 A0A5G2RE18	AKT2 TSC1 TSC2	Sus scrofa (pig)
Transport of bile salts and organic acids, metal ions and amine compounds	Choline transporter-like protein 2 Choline transporter-like protein 4 Choline transporter-like protein Choline transporter-like protein Multidrug and toxin extrusion protein Multidrug and toxin extrusion protein Solute carrier family 10 member 6 Solute carrier family 14 member 2 Urea transporter 1	A0A287ARM7 A0A287BPI3 A0A8W4FLB7 A5PF08 F1RQG4 F1S542 F1S584 F1SDC6 I3LIG7	CTL2 CTL4 SLC10A6 SLC14A1 SLC14A2 SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC47A1 SLC47A2 TPPT1	Sus scrofa (pig)
Fructose biosynthesis	Aldo-keto reductase family 1 member B1 Sorbitol dehydrogenase	A0A287AT21 A0A5G2R274	AKR1B1 SORD	Sus scrofa (pig)	G58161NS
Vitamin B2 (riboflavin) metabolism	Ectonucleotide pyrophosphatase/phosphodiesterase 1 FAD synthase Riboflavin transporter Riboflavin transporter Tartrate-resistant acid phosphatase type 5 riboflavin kinase	A0A287AT99 A0A480TEK5 A0A5G2RJ73 F1RSN6 F1S866 P09889	ACP5 ENPP1 FLAD1 RFK SLC52A1 SLC52A2 SLC52A3	Sus scrofa (pig)
Lectin pathway of complement activation	Collectin subfamily member 10 Collectin-11 Ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) Ficolin (collagen/fibrinogen domain containing) 1 MBL associated serine protease 1 MBL associated serine protease 2 Mannose-binding protein C	A0A287ATF0 A0A5G2QE59 A0A5G2QFX9 A0A5G2QP75 A0A8W4FNY0 I3LEW0 K7GKU8	COLEC10 COLEC11 FCN1 FCN2 MASP1 MASP2 MBL2	Sus scrofa (pig)	G49108TO G57321FI
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin-C Prostate transmembrane protein, androgen induced 1 Serine/threonine-protein kinase receptor TGF-beta receptor type-1 Transforming growth factor beta-1 proprotein Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein protein-tyrosine-phosphatase	A0A287ATZ7 A0A287AZA7 A0A287BBB7 A0A287BE69 A0A287BGG6 A0A287BLR9 A0A287BQ73 A0A2C9F3G2 A0A5G2RC56 A7U5U2 E9LHE5 F1CK19 F1S911 P07200 P0CG68 P84024	BAMBI MADH3 MTMR4 PMEPA1 RPS27A SMAD2 SMAD3 SMAD7 SMURF2 STUB1 Smad7 TGFB1 TGFBR1 TGFBR2 UBA52 UBB UBC bambi	Sus scrofa (pig)
Toll Like Receptor 9 (TLR9) Cascade	Early endosome antigen 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Rabenosyn, RAB effector Toll-like receptor 9 non-specific serine/threonine protein kinase	A0A287AVI7 A0A287BHR8 A0A5G2RJ76 F1SAI0 Q5I2M3	EEA1 PIK3C3 PIK3R4 RBSN TLR9	Sus scrofa (pig)
Activation of the phototransduction cascade	Cyclic nucleotide gated channel subunit beta 1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Phosphodiesterase Rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Rhodopsin cGMP-gated cation channel alpha-1	A0A287AW90 A0A5G2R841 A0A8W4FII8 F1RF40 F1RL89 O18766	CNGA1 CNGB1 GNB1 PDE6A PDE6G RHO RHO1	Sus scrofa (pig)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl peptidase 4 Free fatty acid receptor 4 G protein subunit beta 3 G protein-coupled receptor 119 Gastrin-releasing peptide Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Leptin Pro-glucagon	A0A287AW90 E7EDN1 F1RTG3 F1SLU8 P01274 P22411 P63153 Q29406	CD26 DPP4 FFAR4 GCG GNB1 GNB3 GPR119 GPR120 GRP LEP O3FAR1 OB OBS	Sus scrofa (pig)	G58161NS
Atorvastatin ADME	ABC-type glutathione-S-conjugate transporter Cytochrome P450 3A Cytochrome P450 3A Cytochrome P450 3A Multidrug resistance protein 1 Paraoxonase Paraoxonase Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member glucuronosyltransferase	A0A287AWR7 A0A287B7I8 A0A8W4FMT0 F1S8V9 F1SBZ0 F1SM17 F1SUN1 F6KQD9 I3LA57 I3LEX8	ABCC2 CYP3A22 CYP3A227 CYP3A29 LOC100522267 PON1 PON3 SLCO1B2 SLCO1B3 SLCO2B1 UGT1A6	Sus scrofa (pig)
Synthesis of 5-eicosatetraenoic acids	Arachidonate 5-lipoxygenase Leukotriene C4 synthase Paraoxonase Paraoxonase Paraoxonase	A0A287AWR7 F1SFA2 F6KQD9 I3LEI1 K7GQZ4	ALOX5 LTC4S PON1 PON2 PON3	Sus scrofa (pig)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	Potassium channel subfamily K member Potassium channel subfamily K member Potassium channel subfamily K member	A0A287AWU0 F1RGV1 F1RRI8	KCNK1 KCNK6 KCNK7	Sus scrofa (pig)
Calnexin/calreticulin cycle	Calnexin Calreticulin Protein disulfide-isomerase	A0A287AXF5 F6QA08 P28491	CALR CANX PDIA3	Sus scrofa (pig)
FGFR1c and Klotho ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor receptor Klotho	A0A287AXR0 F1RSR6 K7GQJ1	FGF23 FGFR1 KL	Sus scrofa (pig)
Hormone ligand-binding receptors	Follicle-stimulating hormone receptor Follitropin subunit beta Glycoprotein hormones alpha chain Gonadotropin releasing hormone receptor 2 Gonadotropin-releasing hormone receptor Lutropin subunit beta Lutropin-choriogonadotropic hormone receptor Progonadoliberin-1 Progonadoliberin Thyrotropin receptor Thyrotropin subunit beta	A0A287AY01 A0A287BBU3 F1SDF3 I3L9Z2 P01219 P01224 P01228 P01232 P16582 P49921 P49922	CGA FSHB FSHR GNRH GNRH1 GNRH2 GNRHR GNRHR2 LHB LHCGR TSHB TSHR	Sus scrofa (pig)
Hyaluronan biosynthesis and export	ATP binding cassette subfamily C member 5 Cell migration inducing hyaluronidase 1 Hyaluronan synthase 2 hyaluronan synthase hyaluronan synthase	A0A287AY60 A0A5G2R512 A0A5G2RIV2 F1S290 Q75R37	ABCC5 CEMIP HAS1 HAS3 SHAS2 shas3	Sus scrofa (pig)	G35674CY
Thyroxine biosynthesis	Dual oxidase 1 Glycoprotein hormones alpha chain Iodotyrosine deiodinase 1 NAD(P)H oxidase (H2O2-forming) NAD(P)H oxidase (H2O2-forming) Sodium iodide symporter Thyroid peroxidase Thyrotropin subunit beta	A0A287AZ10 A0A287B129 A0A287BQ51 K7GR01 P01219 P01224 Q8HZK3 Q9GJX7	CGA DUOX1 DUOX2 IYD SLC5A5 TPO TSHB	Sus scrofa (pig)
Syndecan interactions	Fibroblast growth factor Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 2 Integrin subunit alpha 6 Integrin subunit alpha V Protein kinase C Syndecan-4 Syndecan Syndecan Syndecan Transforming growth factor beta-1 proprotein Vitronectin	A0A287AZ66 A0A287B286 A0A287BGK8 A0A5G2QY83 A0A5G2R7K7 A0A5K1V6L8 A0A8W4FC88 F1RV14 F1S0L5 F1SMF4 K7GNF5 K7GQ83 P07200 P48819 Q8HZJ6	FGF2 ITGA2 ITGA6 ITGAV ITGB1 ITGB3 ITGB4 ITGB5 PRKCA SDC1 SDC2 SDC3 SDC4 TGFB1 VTN	Sus scrofa (pig)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	26S protease regulatory subunit 4 Autocrine motility factor receptor Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Polyubiquitin-C UBX domain protein 1 Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	A0A287AZA7 A0A2C9F3G2 A0A480HSN1 A0A5G2QHB2 A7U5U2 F1RF19 F1RS44 F1S911 F2Z5J1 P0CG68	AMFR ENGASE NGLY1 PSMC1 RPS27A UBA52 UBB UBC UBXN1	Sus scrofa (pig)	G03934XO G25577BM G28233ME G51034LA G86419OL
Lysosomal oligosaccharide catabolism	Alpha-mannosidase Alpha-mannosidase Beta-mannosidase alpha-mannosidase	A0A287AZU8 A0A5G2R0E8 F1S106 I3LHM6	MAN2B1 MAN2B2 MAN2C1 MANBA	Sus scrofa (pig)	G00027MO G25577BM G28233ME G70323CJ G90333CG
Apoptotic execution phase	B-cell receptor-associated protein Caspase-8 Dynamin-1-like protein non-specific serine/threonine protein kinase	A0A287B0C4 A0A287BMW9 F1S2A8 Q56VC3	BCAP31 CASP8 DNM1L STK24	Sus scrofa (pig)
Arachidonic acid metabolism	Fatty-acid amide hydrolase 1 fatty acid amide hydrolase	A0A287B2N9 Q9TUI8	FAAH FAAH1	Sus scrofa (pig)
Glycerophospholipid biosynthesis	Acylglycerol kinase, mitochondrial Copine 1 Copine 3 Copine 6	A0A287B2X0 B8XSJ0 F1S4V8 F1SGL6	AGK CPNE1 CPNE3 CPNE6	Sus scrofa (pig)
Heme biosynthesis	5-aminolevulinate synthase 5-aminolevulinate synthase Albumin Broad substrate specificity ATP-binding cassette transporter ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 Cytochrome c oxidase assembly homolog COX15 Delta-aminolevulinic acid dehydratase FLVCR heme transporter 1 Ferrochelatase Protoheme IX farnesyltransferase, mitochondrial Protoporphyrinogen oxidase Uroporphyrinogen decarboxylase coproporphyrinogen oxidase hydroxymethylbilane synthase uroporphyrinogen-III synthase	A0A287B3T2 A0A287BAY9 A0A287BGW4 A0A5S6GWJ4 A0SNU8 F1RUD4 F1S197 F1S2X6 F1S365 F1S8W1 F1SIX5 F1SK95 F1SS45 I3LT93 Q8MIB3	ABCG2 ABCG2A ALAD ALAS1 ALAS2 ALB BMDP COX10 COX15 CPOX FECH FLVCR1 HMBS PPOX UROD UROS	Sus scrofa (pig)
N-glycan trimming and elongation in the cis-Golgi	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Glycoprotein endo-alpha-1,2-mannosidase	A0A287B4B5 Q0KKC2	MANEA MGAT1	Sus scrofa (pig)	G58161NS

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