GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **301 - 325** of **360** in total

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Pathway Name	Protein Name ▲	UniProt ID	Gene Symbol	Organism
ABO blood group biosynthesis	Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2	Q10982 Q29043	FUT1 FUT2	Sus scrofa (pig)
Electric Transmission Across Gap Junctions	Gap junction gamma-1 protein Gap junction protein Gap junction protein Pannexin Pannexin	A0A287AL56 A0A287B8K3 A4GVD1 F1RXR8 F1RY20	GJA10 GJA7 GJC1 GJD2 PANX PANX1 PANX2	Sus scrofa (pig)
Glycerophospholipid catabolism	Glycerophosphocholine cholinephosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1 Patatin like phospholipase domain containing 6	A0A286ZW95 I3LLY2 Q58D68	ENPP6 GDE1 PNPLA6	Sus scrofa (pig)
Platelet Aggregation (Plug Formation)	Glycoprotein IX platelet Glycoprotein Ib platelet subunit beta Glycoprotein V platelet Prothrombin von Willebrand factor	B7TY21 B7TY22 F1SIB1 F1SL22 K7GN20	F2 GP1BB GP5 GP9 GPIX GPIbB VWF	Sus scrofa (pig)
PTK6 promotes HIF1A stabilization	Glycoprotein nmb Hypoxia-inducible factor 1-alpha Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Tyrosine-protein kinase non-specific serine/threonine protein kinase	A0A286ZJF6 A0A286ZYS4 A0A287B2Q0 A0A5G2QBP1 F1SHN7 Q01580	DTR EGFR GPNMB HBEGF HEGFL HIF1A LRRK2 PTK6	Sus scrofa (pig)
Insulin receptor signalling cascade	Growth factor receptor bound protein 2 Growth factor receptor-bound protein 10 Insulin SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A286ZUQ0 A0A5K1V5Y3 B5KFD7 B6E241 F1SCL0 P01315	GRB2 Grb10 INS INSR SHC1 SOS1	Sus scrofa (pig)
SHC-related events triggered by IGF1R	Growth factor receptor bound protein 2 Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor II SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A286ZUQ0 A0A287BJL7 A0A5K1V5Y3 B6E241 F1CK17 P16545 P23695	GRB2 IGF1 IGF1R IGF2 SHC1 SOS1	Sus scrofa (pig)
Growth hormone receptor signaling	Growth hormone 1 Mitogen-activated protein kinase Mitogen-activated protein kinase Prolactin receptor Prolactin SH2B adaptor protein 1 Somatotropin Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A287BAQ6 A0A480NH74 A0A5G2RG05 A0A5S6I4D7 F1RFI0 F1RT53 O19064 P01238 P01248 Q6JTA8	GH1 JAK2 LYN MAPK1 MAPK3 PRL PRLR PTPN1 SH2B1	Sus scrofa (pig)
MET Receptor Activation	HGF activator Hepatocyte growth factor receptor Hepatocyte growth factor Hepsin Serine peptidase inhibitor, Kunitz type 1 Serine peptidase inhibitor, Kunitz type 2	A0A286ZMW3 A0A287BCY0 A0A287BHH9 A0A5G2R148 F1SB93 Q2QLE0	HGF HGFAC HPN MET SPINT1 SPINT2	Sus scrofa (pig)
DDX58/IFIH1-mediated induction of interferon-alpha/beta	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Interferon regulatory factor 3 Mitochondrial antiviral signaling protein Mitochondrial import receptor subunit TOM70 TANK binding kinase 1	A0A286ZKC5 A0A287AL42 A0A480UKD4 A0A5K1V3V4 A0A8I8C3K7 K7GM32 O02705	HSP90A HSP90AA1 HSP90AB1 HSPCA IRF3 MAVS TBK1 TOMM70	Sus scrofa (pig)
The NLRP3 inflammasome	Heat shock protein HSP 90-beta NACHT, LRR and PYD domains-containing protein 3 P2X purinoceptor Pannexin Thioredoxin-interacting protein Thioredoxin	A0A286ZKC5 A0A287B8K3 A0A5G2Q9S8 F1RNN5 H2EW08 Q2HY40	HSP90AB1 NLRP3 P2RX7 PANX PANX1 TXN TXNIP	Sus scrofa (pig)
MET interacts with TNS proteins	Hepatocyte growth factor receptor Hepatocyte growth factor Integrin beta Tensin 3 Tensin-4	F1RXE4 F1SB93 F1ST78 K7GQ83 Q2QLE0	HGF ITGB1 MET TNS3 TNS4	Sus scrofa (pig)
MET activates STAT3	Hepatocyte growth factor receptor Hepatocyte growth factor Signal transducer and activator of transcription 3 Signal transducer and activator of transcription	A0A2C9F3G4 F1SB93 Q19S50 Q2QLE0	HGF MET STAT3	Sus scrofa (pig)
MET activates PTK2 signaling	Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein kinase	F1SB93 K7GPR7 Q2QLE0	HGF MET SRC	Sus scrofa (pig)
Drug-mediated inhibition of MET activation	Hepatocyte growth factor receptor Hepatocyte growth factor	F1SB93 Q2QLE0	HGF MET	Sus scrofa (pig)
Sema4D mediated inhibition of cell attachment and migration	Hepatocyte growth factor receptor Plexin B1 RAS related Ras-related C3 botulinum toxin substrate 1 Rho GTPase-activating protein 35 Semaphorin 4D Transforming protein RhoA	A0A5K1TV69 A0A8W4FI56 F1RHW4 F1RM07 F1SLI0 I3LVS7 Q2QLE0	ARHGAP35 MET PLXNB1 RAC1 RHOA RRAS SEMA4D	Sus scrofa (pig)
Orexin and neuropeptides FF and QRFP bind to their respective receptors	Hypocretin neuropeptide precursor Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Pyroglutamylated RFamide peptide receptor	A0A287A138 F1RUN6 F1S1T5 F1SUD0 O62809 O77668	HCRT HCRTR1 HCRTR2 NPFFR1 NPFFR2 ORX OX PPOX QRFPR	Sus scrofa (pig)
Phosphorylation of CD3 and TCR zeta chains	Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II DR-alpha MHC class II antigen MHC class II histocompatibility antigen SLA-DRB1 Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 SLA class II histocompatibility antigen, DQ haplotype D alpha chain SLA-DQ beta1 domain T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein protein-tyrosine-phosphatase protein-tyrosine-phosphatase	A0A286ZKB7 A0A286ZUJ9 A0A287AC24 A0A287AT33 A0A287B968 A0A287BD80 A0A287BF11 A0A287BQ31 A0A5G2QCN4 A0A8W4F9V5 A0A8W4FBN9 A0A8W4FJW4 A0A8W4FNK4 A0A8W4FP49 A0A8X9AEU9 F1RXA1 F1S5F1 F1S6S1 F1S975 F1SJ27 F1SV94 I3L556 I3LAQ5 K7GS60 P15981 Q5PXD3 Q764N2 Q7YQ94 Q85ZW4	CD247 CD3D CD3E CD3G CD4 CSK DRA HLA-DRA LCK LOC100153139 PAG1 PTPN22 PTPRC SLA-DQA SLA-DQA1 SLA-DQB1 SLA-DR SLA-DRA SLA-DRA1 SLA-DRB1	Sus scrofa (pig)
PD-1 signaling	Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II DR-alpha MHC class II antigen MHC class II histocompatibility antigen SLA-DRB1 Programmed cell death 1 ligand 2 Programmed cell death 1 SLA class II histocompatibility antigen, DQ haplotype D alpha chain SLA-DQ beta1 domain T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein	A0A286ZKB7 A0A286ZUJ9 A0A287A1C3 A0A287AC24 A0A287AT33 A0A287B968 A0A287BF11 A0A287BQ31 A0A480LMF4 A0A5G2QCN4 A0A5G2QPQ3 A0A8W4F9V5 A0A8W4FBN9 A0A8W4FJW4 A0A8W4FNK4 A0A8W4FP49 A0A8X9AEU9 F1S6S1 F1S975 F1SJ27 F1SV94 I3L556 I3LAQ5 K7GS60 P15981 Q5PXD3 Q764N2 Q7YQ94 Q85ZW4	CD247 CD3D CD3E CD3G CD4 CSK DRA HLA-DRA LCK LOC100153139 PDCD1 PDCD1LG2 PTPN11 SLA-DQA SLA-DQA1 SLA-DQB1 SLA-DR SLA-DRA SLA-DRA1 SLA-DRB1	Sus scrofa (pig)
Translocation of ZAP-70 to Immunological synapse	Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II DR-alpha MHC class II antigen MHC class II histocompatibility antigen SLA-DRB1 SLA class II histocompatibility antigen, DQ haplotype D alpha chain SLA-DQ beta1 domain T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase Uncharacterized protein protein-tyrosine-phosphatase	A0A286ZKB7 A0A286ZUJ9 A0A287AC24 A0A287AT33 A0A287B968 A0A287BD80 A0A287BF11 A0A287BQ31 A0A5G2QCN4 A0A8W4F9V5 A0A8W4FBN9 A0A8W4FJW4 A0A8W4FNK4 A0A8W4FP49 A0A8X9AEU9 F1S6S1 F1S975 F1SV94 I3L556 I3LAQ5 K7GS60 P15981 Q5PXD3 Q764N2 Q7YQ94 Q85ZW4	CD247 CD3D CD3E CD3G CD4 DRA HLA-DRA LCK LOC100153139 PTPN22 SLA-DQA SLA-DQA1 SLA-DQB1 SLA-DR SLA-DRA SLA-DRA1 SLA-DRB1	Sus scrofa (pig)
Costimulation by the CD28 family	Ig-like domain-containing protein Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5G2QMX5 A0A5K1UB41 F1S916 F1SKR9	ICOSLG PIK3CA PIK3R1 PIK3R2	Sus scrofa (pig)
Signaling by Activin	Inhibin alpha chain Inhibin beta A chain Inhibin beta B chain Mitogen-activated protein kinase Mitogen-activated protein kinase Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog Serine/threonine-protein kinase receptor Serine/threonine-protein kinase receptor Transforming growth factor beta receptor 3 receptor protein serine/threonine kinase receptor protein serine/threonine kinase	A0A287AAP7 A0A287BE69 A0A287BJX6 A0A287BPF5 A0A287BPI7 A0A480NH74 A0A5G2RG05 A0A5K1U747 F1S0H6 P03970 P04087 P84024 Q9GKQ9	ACVR1B ACVR1C ACVR2A ACVR2B INHA INHBA INHBB MADH3 MADH4 MAPK1 MAPK3 SMAD2 SMAD3 SMAD4 TGFBR3	Sus scrofa (pig)
Elevation of cytosolic Ca2+ levels	Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Short transient receptor potential channel 3 isoform a Transient receptor potential cation channel subfamily C member 6 Transient receptor potential cation channel subfamily C member 7	A0A286ZYA9 A0A287AVK8 A0A287BL11 A0A5G2QGJ3 A0A5G2QQ93 A0A5G2RCE3 A0A8W4FN26 F1RI70 F1RNN5 F1S1U0 I3L7H5 I3LUU3	ITPR1 ITPR3 P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 TRPC3 TRPC6 TRPC7	Sus scrofa (pig)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor II Tyrosine-protein kinase receptor	A0A287B726 A0A287BJL7 A0A5K1VEI3 F1CK17 I3LLF1 P16545 P23695	IGF1 IGF1R IGF2 IRS1 IRS2 IRS4	Sus scrofa (pig)
IRS-mediated signalling	Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A287B726 A0A5K1UB41 A0A8X9AEI7 F1S916 F1SKR9 I3LLF1	IRS1 IRS2 PIK3CA PIK3CB PIK3R1 PIK3R2	Sus scrofa (pig)

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