GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **326 - 350** of **360** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Regulation of IFNG signaling	E3 SUMO-protein ligase PIAS1 isoform 2 Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Signal transducer and activator of transcription Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A286ZLI2 A0A286ZN85 A0A287B963 A0A287BNZ9 A7WLH8 E5EZY0 E7CR04 F1S692 I3LJA1 O19064 P17803	IFNG IFNGR1 IFNGR2 JAK1 JAK2 PIAS1 PTPN2 SOCS1 SOCS3 STAT1 SUMO1 socs1	Sus scrofa (pig)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor II Tyrosine-protein kinase receptor	A0A287B726 A0A287BJL7 A0A5K1VEI3 F1CK17 I3LLF1 P16545 P23695	IGF1 IGF1R IGF2 IRS1 IRS2 IRS4	Sus scrofa (pig)
Interleukin-10 signaling	Interleukin 10 receptor subunit alpha Interleukin-10 receptor subunit beta Interleukin-10 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase	A0A286ZLI2 A0A286ZQU5 A0A2C9F3G4 F1S3L9 F1SAM5 Q19S50 Q29055	IL10 IL10RA IL10RB JAK1 STAT3 TYK2	Sus scrofa (pig)
Interleukin-12 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 12 receptor subunit beta 2 Interleukin-12 subunit alpha Interleukin-12 subunit beta Protein disulfide-isomerase Signal transducer and activator of transcription Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase	A0A286ZLI2 A0A5G2QAF8 A0A5G2RDD7 A0A5S6GA10 E1U8C4 F1S3L9 F1S826 O19064 Q28938	IL12A IL12B IL12RB1 IL12RB2 JAK1 JAK2 LOC100736717 P4HB STAT4 TYK2 stat4	Sus scrofa (pig)
Interleukin-23 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 23 receptor Interleukin-12 subunit beta Interleukin-23 subunit alpha Protein disulfide-isomerase Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A2C9F3G4 A0A5G2QAF8 A0A5G2R3H9 A0A5G2RDD7 E1U8C4 F1S3L9 O19064 Q19S50 Q28938 Q9N2H9	IL12B IL12RB1 IL23A IL23R JAK2 LOC100736717 P4HB SGRF STAT3 STAT4 TYK2 stat4	Sus scrofa (pig)
Interleukin-2 signaling	Interleukin 2 receptor gamma Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 SHC-transforming protein 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase non-specific protein-tyrosine kinase	A0A0A0MY60 A0A286ZLI2 A0A287A7A4 A0A287AFR0 A0A5K1V5Y3 E7CR01 F1RJS6 F1SV94 K7GSE8 P26891 Q76KD0	IL2 IL2RA IL2RB IL2RG JAK1 JAK3 LCK PTK2B SHC1 STAT5A STAT5B stat5B	Sus scrofa (pig)
Signaling by Insulin receptor	Insulin Tyrosine-protein kinase receptor	F1SCL0 P01315	INS INSR	Sus scrofa (pig)
Phase 4 - resting membrane potential	ATP-sensitive inward rectifier potassium channel 12 isoform X1 ATP-sensitive inward rectifier potassium channel 14 Inward rectifier potassium channel 2 Inward rectifier potassium channel 4 Potassium channel subfamily K member 10 isoform 2 Potassium channel subfamily K member 12 Potassium channel subfamily K member 13 Potassium channel subfamily K member 5 Potassium channel subfamily K member Potassium channel subfamily K member Potassium channel subfamily K member Potassium channel subfamily K member Potassium channel subfamily K member Potassium two pore domain channel subfamily K member 15 Potassium two pore domain channel subfamily K member 16 Potassium two pore domain channel subfamily K member 17 Potassium two pore domain channel subfamily K member 4	A0A286ZMZ4 A0A287A5K0 A0A287A685 A0A287AIG4 A0A287AWU0 A0A287B0A6 F1RGV1 F1RL84 F1RQN9 F1RRI8 F1RVQ8 F1RVQ9 F1SDA6 F1SDS1 F1SKP8 F1SQH8 O18839	IRK1 KCNJ12 KCNJ14 KCNJ2 KCNJ4 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK3 KCNK4 KCNK5 KCNK6 KCNK7 KCNK9	Sus scrofa (pig)
IRS-mediated signalling	Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A287B726 A0A5K1UB41 A0A8X9AEI7 F1S916 F1SKR9 I3LLF1	IRS1 IRS2 PIK3CA PIK3CB PIK3R1 PIK3R2	Sus scrofa (pig)
Elevation of cytosolic Ca2+ levels	Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Short transient receptor potential channel 3 isoform a Transient receptor potential cation channel subfamily C member 6 Transient receptor potential cation channel subfamily C member 7	A0A286ZYA9 A0A287AVK8 A0A287BL11 A0A5G2QGJ3 A0A5G2QQ93 A0A5G2RCE3 A0A8W4FN26 F1RI70 F1RNN5 F1S1U0 I3L7H5 I3LUU3	ITPR1 ITPR3 P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 TRPC3 TRPC6 TRPC7	Sus scrofa (pig)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	Potassium channel subfamily K member Potassium channel subfamily K member Potassium channel subfamily K member	A0A287AWU0 F1RGV1 F1RRI8	KCNK1 KCNK6 KCNK7	Sus scrofa (pig)
TWIK-related alkaline pH activated K+ channel (TALK)	Potassium two pore domain channel subfamily K member 16 Potassium two pore domain channel subfamily K member 17	A0A287A685 F1RVQ8	KCNK16 KCNK17	Sus scrofa (pig)
Opsins	Long-wave-sensitive opsin 1 Melanopsin Opsin 5 Retinal G protein coupled receptor Retinal pigment epithelium-derived rhodopsin homolog Rhodopsin	A0A287BQI1 F1S135 F1SEP7 I3LTK7 O18766 Q5IR81	LOC494564 OPN4 OPN5 RGR RHO RHO1 RRH	Sus scrofa (pig)
RUNX3 regulates CDKN1A transcription	Cellular tumor antigen p53 Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Runt-related transcription factor Transforming growth factor beta-1 proprotein Zinc finger homeobox 3	A0A5G2QVF3 F1S397 P07200 P84024 Q9GKQ9 Q9TUB2	MADH3 MADH4 P53 RUNX3 SMAD3 SMAD4 TGFB1 TP53 ZFHX3	Sus scrofa (pig)
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	alpha-1,2-Mannosidase alpha-1,2-Mannosidase alpha-1,2-Mannosidase	A0A480JM90 A0A481C5C8 I3L826	MAN1A1 MAN1A2 MAN1C1	Sus scrofa (pig)	G70323CJ
Lysosomal oligosaccharide catabolism	Alpha-mannosidase Alpha-mannosidase Beta-mannosidase alpha-mannosidase	A0A287AZU8 A0A5G2R0E8 F1S106 I3LHM6	MAN2B1 MAN2B2 MAN2C1 MANBA	Sus scrofa (pig)	G00027MO G25577BM G28233ME G70323CJ G90333CG
N-glycan trimming and elongation in the cis-Golgi	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Glycoprotein endo-alpha-1,2-mannosidase	A0A287B4B5 Q0KKC2	MANEA MGAT1	Sus scrofa (pig)	G58161NS
Norepinephrine Neurotransmitter Release Cycle	Amine oxidase PTPRF interacting protein alpha 1 PTPRF interacting protein alpha 2 PTPRF interacting protein alpha 3 PTPRF interacting protein alpha 4 Ras-related protein Rab-3A Regulating synaptic membrane exocytosis 1 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Synaptotagmin Syntaxin-1A Syntaxin-binding protein 1 TSPO associated protein 1 Unc-13 homolog B Vesicle-associated membrane protein 2	A0A286ZMF4 A0A287A9U9 A0A287AA12 A0A287BFR7 A0A5G2QEP9 A0A5G2QIZ6 A0A5G2QUF9 A0A5G2R276 F1RGA3 F1RS11 F1RTS7 F1RX00 F1RYK1 O02713 Q06AU3	MAOA OCT2 PPFIA1 PPFIA2 PPFIA3 PPFIA4 RAB3A RIMS1 SLC22A1 SLC22A2 STX1A STXBP1 SYT1 TSPOAP1 UNC13B VAMP2	Sus scrofa (pig)
Gastrin-CREB signalling pathway via PKC and MAPK	Mitogen-activated protein kinase Mitogen-activated protein kinase Mitogen-activated protein kinase Ribosomal protein S6 kinase Ribosomal protein S6 kinase Ribosomal protein S6 kinase	A0A287A3K5 A0A287BHE2 A0A480NH74 A0A5G2R6J0 A0A5G2RG05 M3VH78	MAPK1 MAPK3 MAPK7 RPS6KA1 RPS6KA2 RPS6KA3	Sus scrofa (pig)
Neurotransmitter release cycle	N-acylethanolamine-hydrolyzing acid amidase	A0A5G2R6W7	NAAA	Sus scrofa (pig)
Organic anion transport	Organic anion transporter 3 Solute carrier family 22 member 11 Solute carrier family 22 member 12 Solute carrier family 22 member 6 Solute carrier family 22 member 7	A0A8W4FD67 I3L7D2 I3LKR0 Q1RPP5 Q70BM6	OAT2 OAT3 SLC22A11 SLC22A12 SLC22A6 SLC22A7 SLC22A8	Sus scrofa (pig)
Organic cation transport	Runt-related transcription factor Solute carrier family 22 member 15 Solute carrier family 22 member 16 Solute carrier family 22 member 18 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3 Solute carrier family 22 member 4 Solute carrier family 22 member 5	A0A286ZXK3 A0A287A9U9 A0A287ABQ9 F1RT02 F1RYX1 F1SAX0 F1SB80 F8SIP5 O02713	OCT2 RUNX1 SLC22A1 SLC22A15 SLC22A16 SLC22A18 SLC22A2 SLC22A3 SLC22A4 SLC22A5	Sus scrofa (pig)
Na+/Cl- dependent neurotransmitter transporters	Solute carrier family 18 member A1 Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 6 member 18 Solute carrier family 6 member 19 Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter Transporter	A0A286ZR77 A0A287A9U9 A0A287AJD7 A0A287AMT4 A0A287AYA7 A0A480E2J0 A0A5G2QRJ4 A0A5G2QXJ4 A0A5G2RG90 A0A5K1V0Y8 A0A8W4FJT1 F1RF13 F1RL70 F1RYN4 F1S024 I3LKJ8 I3LR93 O02713	OCT2 SLC18A1 SLC22A1 SLC22A2 SLC6A1 SLC6A11 SLC6A12 SLC6A13 SLC6A14 SLC6A15 SLC6A18 SLC6A19 SLC6A2 SLC6A20 SLC6A3 SLC6A5 SLC6A6 SLC6A7 SLC6A9	Sus scrofa (pig)
Abacavir transmembrane transport	Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3	A0A287A9U9 F1SB80 O02713	OCT2 SLC22A1 SLC22A2 SLC22A3	Sus scrofa (pig)
Platelet homeostasis	P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Platelet-activating factor acetylhydrolase	A0A286ZJX8 A0A286ZYA9 A0A287AVK8 A0A5G2QGJ3 A0A8W4FN26 F1RI70 F1RNN5 I3L7H5	P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 PAFAH2	Sus scrofa (pig)

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