GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source Last Updated
Reactome March 20, 2024
ECODAB April 1, 2019
Displaying entries 76 - 100 of 360 in total
Pathway Name Protein Name ▼ UniProt ID Gene Symbol Organism GlyTouCan ID
Syndecan interactions
  • FGF2
  • ITGA2
  • ITGA6
  • ITGAV
  • ITGB1
  • ITGB3
  • ITGB4
  • ITGB5
  • PRKCA
  • SDC1
  • SDC2
  • SDC3
  • SDC4
  • TGFB1
  • VTN
Sus scrofa (pig)
FGFR1b ligand binding and activation
  • FGF1
  • FGF10
  • FGF2
  • FGF22
  • FGF3
  • FGFR1
  • TGFBR3
Sus scrofa (pig)
FGFR1c and Klotho ligand binding and activation
  • FGF23
  • FGFR1
  • KL
Sus scrofa (pig)
SHC-mediated cascade:FGFR1
  • FGF1
  • FGF10
  • FGF2
  • FGF20
  • FGF22
  • FGF23
  • FGF3
  • FGF4
  • FGF5
  • FGF6
  • FGF8
  • FGF9
  • FGFR1
  • Fgf4
  • GRB2
  • HRAS
  • KL
  • KRAS
  • NRAS
  • SHC1
  • SOS1
Sus scrofa (pig)
PI-3K cascade:FGFR1
  • FGF1
  • FGF10
  • FGF2
  • FGF20
  • FGF22
  • FGF23
  • FGF3
  • FGF4
  • FGF5
  • FGF6
  • FGF8
  • FGF9
  • FGFR1
  • Fgf4
  • GAB1
  • GRB2
  • KL
  • PIK3CA
  • PIK3R1
  • PTPN11
Sus scrofa (pig)
Downstream signaling of activated FGFR1
  • FGF1
  • FGF10
  • FGF2
  • FGF20
  • FGF22
  • FGF23
  • FGF3
  • FGF4
  • FGF5
  • FGF6
  • FGF8
  • FGF9
  • FGFR1
  • FLRT1
  • FLRT2
  • FLRT3
  • Fgf4
  • KL
Sus scrofa (pig)
FGFR4 ligand binding and activation
  • FGF1
  • FGF16
  • FGF18
  • FGF19
  • FGF2
  • FGF20
  • FGF23
  • FGF4
  • FGF6
  • FGF8
  • FGF9
  • FGFR4
  • Fgf4
Sus scrofa (pig)
SHC-mediated cascade:FGFR4
  • FGF1
  • FGF16
  • FGF18
  • FGF19
  • FGF2
  • FGF20
  • FGF23
  • FGF4
  • FGF6
  • FGF8
  • FGF9
  • FGFR4
  • Fgf4
  • GRB2
  • HRAS
  • KLB
  • KRAS
  • NRAS
  • SHC1
  • SOS1
Sus scrofa (pig)
PI-3K cascade:FGFR4
  • FGF1
  • FGF16
  • FGF18
  • FGF19
  • FGF2
  • FGF20
  • FGF23
  • FGF4
  • FGF6
  • FGF8
  • FGF9
  • FGFR4
  • Fgf4
  • GAB1
  • GRB2
  • KLB
  • PIK3CA
  • PIK3R1
  • PTPN11
Sus scrofa (pig)
PI3K Cascade
  • FGF1
  • FGF10
  • FGF16
  • FGF18
  • FGF19
  • FGF2
  • FGF20
  • FGF22
  • FGF23
  • FGF3
  • FGF4
  • FGF5
  • FGF6
  • FGF8
  • FGF9
  • FGFR1
  • FGFR4
  • FLT3
  • FLT3LG
  • Fgf4
  • GAB1
  • GAB2
  • GRB2
  • IRS1
  • IRS2
  • KL
  • KLB
  • PIK3C3
  • PIK3CA
  • PIK3CB
  • PIK3R1
  • PIK3R2
  • PIK3R4
  • PTPN11
  • TLR9
Sus scrofa (pig)
FRS-mediated FGFR1 signaling
  • FGF1
  • FGF10
  • FGF2
  • FGF20
  • FGF22
  • FGF23
  • FGF3
  • FGF4
  • FGF5
  • FGF6
  • FGF8
  • FGF9
  • FGFR1
  • FRS3
  • Fgf4
  • GRB2
  • HRAS
  • KL
  • KRAS
  • NRAS
  • PTPN11
  • SOS1
Sus scrofa (pig)
FRS-mediated FGFR4 signaling
  • FGF1
  • FGF16
  • FGF18
  • FGF19
  • FGF2
  • FGF20
  • FGF23
  • FGF4
  • FGF6
  • FGF8
  • FGF9
  • FGFR4
  • FRS3
  • Fgf4
  • GRB2
  • HRAS
  • KLB
  • KRAS
  • NRAS
  • PTPN11
  • SOS1
Sus scrofa (pig)
FCGR activation
  • CD247
  • CD3G
  • FCGR1A
  • FCGR2B
  • FCGR3A
  • FYN
  • HCK
  • IGKV5-2
  • LOC100125542
  • LOC100523213
  • LYN
  • SRC
  • YES1
Sus scrofa (pig)
Arachidonic acid metabolism
  • FAAH
  • FAAH1
Sus scrofa (pig)
Signal regulatory protein family interactions
  • CD47
  • DAP12
  • FYB1
  • GRB2
  • LOC100736623
  • LOC100739707
  • LOC102161654
  • PTK2B
  • SIRPA
  • SKAP2
  • TYROBP
Sus scrofa (pig)
Class C/3 (Metabotropic glutamate/pheromone receptors)
  • CASR
  • GABBR1
  • GABBR2
  • GPRC6A
  • GRM1
  • GRM2
  • GRM3
  • GRM4
  • GRM5
  • GRM6
  • GRM7
  • GRM8
  • LOC100154902
  • PCAR1
  • TAS1R1
  • TAS1R2
  • TAS1R3
  • TAS2R1
  • TAS2R10
  • TAS2R16
  • TAS2R3
  • TAS2R39
  • TAS2R4
  • TAS2R40
  • TAS2R41
  • TAS2R7
  • TAS2R9
Sus scrofa (pig)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
  • ECSIT
  • MAP3K1
  • TRAF6
Sus scrofa (pig)
MyD88 cascade initiated on plasma membrane
  • ECSIT
  • MAP3K1
  • TRAF6
Sus scrofa (pig)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane
  • ECSIT
  • MAP3K1
  • TIRAP
  • TRAF6
Sus scrofa (pig)
Nuclear signaling by ERBB4
  • APH1A
  • APH1B
  • ERBB4
  • ESR
  • ESR1
  • NCSTN
  • NR3A1
  • PSEN1
  • PSEN2
  • SRC
  • STAT5A
  • WWOX
  • YAP1
Sus scrofa (pig)
ESR-mediated signaling
  • ESR
  • ESR1
  • ESR2
  • FKBP4
  • FKBP5
  • HSP90A
  • HSP90AA1
  • HSP90AB1
  • HSPCA
  • NR3A1
  • PPP5C
  • PTGES3
Sus scrofa (pig)
Signaling by Erythropoietin
  • EPOR
  • IRS2
  • JAK2
  • LYN
Sus scrofa (pig)
Erythropoietin activates RAS
  • EPO
  • EPOR
  • GRB2
  • IRS2
  • JAK2
  • LYN
  • RAPGEF1
  • SHC1
  • VAV1
Sus scrofa (pig)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)
  • EPO
  • EPOR
  • GAB1
  • IRS2
  • JAK2
  • LYN
  • PIK3CA
  • PIK3CB
  • PIK3CD
  • PIK3CG
  • PIK3R1
  • PIK3R5
Sus scrofa (pig)
Interleukin-4 and Interleukin-13 signaling
  • HSP90B1
  • IL13
  • IL13RA1
  • IL13RA2
  • IL2RG
  • IL4
  • IL4R
  • JAK1
  • JAK2
  • JAK3
  • SOCS1
  • SOCS5
  • STAT1
  • STAT3
  • STAT6
  • TYK2
  • socs1
Sus scrofa (pig)

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024