GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **126 - 150** of **360** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
PI3K Cascade	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fms related receptor tyrosine kinase 3 ligand GRB2 associated binding protein 1 GRB2 associated binding protein 2 Growth factor receptor bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Klotho beta Klotho Multifunctional fusion protein Phosphatidylinositol 3-kinase catalytic subunit type 3 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Toll-like receptor 9 Tyrosine-protein phosphatase non-receptor type non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A287AAE4 A0A287AFX3 A0A287AXR0 A0A287B3V5 A0A287B630 A0A287B726 A0A287B929 A0A287BG34 A0A287BGK8 A0A287BHR8 A0A480ECT1 A0A480LMF4 A0A5G2QUY7 A0A5G2R7G2 A0A5K1UB41 A0A8X9AEI7 B6E241 F1RM38 F1RSR6 F1RY78 F1RY80 F1S3B8 F1S916 F1SAI0 F1SET9 F1SKR9 F1SMG2 I3L560 I3LLF1 I3LR27 K7GMT0 K7GQJ1 Q5I2M3 Q95L12	FGF1 FGF10 FGF16 FGF18 FGF19 FGF2 FGF20 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF8 FGF9 FGFR1 FGFR4 FLT3 FLT3LG Fgf4 GAB1 GAB2 GRB2 IRS1 IRS2 KL KLB PIK3C3 PIK3CA PIK3CB PIK3R1 PIK3R2 PIK3R4 PTPN11 TLR9	Sus scrofa (pig)
Abacavir transmembrane transport	Solute carrier family 22 member 1 Solute carrier family 22 member 2 Solute carrier family 22 member 3	A0A287A9U9 F1SB80 O02713	OCT2 SLC22A1 SLC22A2 SLC22A3	Sus scrofa (pig)
Neurotransmitter clearance	Acetylcholinesterase Solute carrier family 22 member 1 Solute carrier family 22 member 2	A0A287A9U9 A0A5G2QVL5 O02713	ACHE OCT2 SLC22A1 SLC22A2	Sus scrofa (pig)
Ciprofloxacin ADME	Albumin Broad substrate specificity ATP-binding cassette transporter ABCG2 Broad substrate specificity ATP-binding cassette transporter ABCG2 Solute carrier family 22 member 1 Solute carrier organic anion transporter family member	A0A287A9U9 A0A287BAY9 A0A5K1U410 A0A5S6GWJ4 Q8MIB3	ABCG2 ABCG2A ALB BMDP SLC22A1 SLCO1A2	Sus scrofa (pig)
Platelet sensitization by LDL	Apolipoprotein B LDL receptor related protein 8 Mitogen-activated protein kinase 14 Platelet and endothelial cell adhesion molecule 1 Platelet endothelial cell adhesion molecule Protein phosphatase 2 regulatory subunit B'gamma Protein phosphatase 2 scaffold subunit Abeta Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase Tyrosine-protein phosphatase non-receptor type	A0A287A9P4 A0A287AG13 A0A287APB4 A0A287BGB1 A0A287BHS8 A0A480LMF4 E7CXS0 F1RQR5 F1RX68 F1S2V7 K7GS31 P54612 P67776 Q95242	APOB ApoER2 LRP8 MAPK14 PECAM1 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PTPN11	Sus scrofa (pig)
Non-integrin membrane-ECM interactions	Tyrosine-protein kinase receptor receptor protein-tyrosine kinase	A0A287A959 A0A287BGA1	DDR1 DDR2	Sus scrofa (pig)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6 Toll/interleukin-1 receptor domain-containing adapter protein	A0A287A8A9 A0A287ABQ5 A7XUJ6 F1SA28	ECSIT MAP3K1 TIRAP TRAF6	Sus scrofa (pig)
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Bactericidal permeability-increasing protein CD180 antigen Integrin beta Integrin subunit alpha M Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 2 Toll-like receptor 4 dynamin GTPase dynamin GTPase dynamin GTPase	A0A287A869 A0A287AK86 A0A287AN09 A0A287B5Y6 A0A287B8X7 A0A287BLV6 A0A287BMU9 A0A480K9W0 A0A5G2REH3 A2SW51 A7BG67 F1S475 I3LCZ7 Q7YRL4	BPI CD14 CD180 DNM1 DNM2 DNM3 ITGAM ITGB2 LBP LY64 LY86 LY96 PLCG2 TICAM2 TLR4	Sus scrofa (pig)
Hyaluronan uptake and degradation	Beta-glucuronidase Beta-hexosaminidase Beta-hexosaminidase CD44 antigen Hyaluronan mediated motility receptor Hyaluronidase Hyaluronidase Lymphatic vessel endothelial hyaluronan receptor 1 Sodium/hydrogen exchanger Stabilin 2	A0A287A7V3 A0A5G2RBP4 A0A5K1TZ96 D0G6X8 F1SGT4 F1SPN9 F1SRK1 F1STQ3 I3LTD0 Q4FAT7	CD44 GUSB HEXA HEXB HMMR HYAL1 HYAL2 LYVE1 SLC9A1 STAB2	Sus scrofa (pig)	G35674CY
GDP-fucose biosynthesis	Fucose kinase GDP-L-fucose synthase GDP-mannose 4,6-dehydratase L-fucose mutarotase Solute carrier family 35 member C1	A0A287A769 A0A5G2QJW6 A0A5G2QRL7 A0A5G2R675 F1SAC0	FCSK FUOM GFUS GMDS SLC35C1	Sus scrofa (pig)	G85196CF G96881BQ
TWIK-related alkaline pH activated K+ channel (TALK)	Potassium two pore domain channel subfamily K member 16 Potassium two pore domain channel subfamily K member 17	A0A287A685 F1RVQ8	KCNK16 KCNK17	Sus scrofa (pig)
Surfactant metabolism	ATP binding cassette subfamily A member 3 Adenosine receptor A2 Adenosine receptor A2 Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor Coiled-coil domain containing 59 Cytoskeleton associated protein 4 Deleted in malignant brain tumors 1 protein GATA binding protein 6 LIM and cysteine rich domains 1 LIM and cysteine-rich domains protein 1 Napsin A aspartic peptidase P2Y purinoceptor 2 Palmitoyltransferase Pepsin A Pro-cathepsin H Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein C Pulmonary surfactant-associated protein D Pulmonary surfactant-associated protein D Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Transcription termination factor 1 adenosine deaminase	A0A287A5E9 A0A287AH87 A0A287AN35 A0A287ANT3 A0A287AYY3 A0A287BDN3 A0A287BPZ1 A0A480WFR8 A0A5G2Q8A7 A0A8W4FD62 A0A8W4FEE8 A7MAK5 F1RLS0 F1S0U5 F1S5A6 F1SBC0 F1SPP8 I3LFJ1 O46427 P00791 P18871 Q3MSM1 Q5PXT2 Q5YA25 Q9N1X4	A2AR ABCA3 ADA2 ADGRF5 ADORA2A ADORA2B ADRA2A ADRA2C CCDC59 CKAP4 CTSH GATA6 LMCD1 NAPSA P2RY2 PGA SFTPB SFTPC SFTPD SLC34A1 SLC34A2 SP-C TTF1 ZDHHC2	Sus scrofa (pig)
Gastrin-CREB signalling pathway via PKC and MAPK	Mitogen-activated protein kinase Mitogen-activated protein kinase Mitogen-activated protein kinase Ribosomal protein S6 kinase Ribosomal protein S6 kinase Ribosomal protein S6 kinase	A0A287A3K5 A0A287BHE2 A0A480NH74 A0A5G2R6J0 A0A5G2RG05 M3VH78	MAPK1 MAPK3 MAPK7 RPS6KA1 RPS6KA2 RPS6KA3	Sus scrofa (pig)
Sphingolipid catabolism	Aldehyde dehydrogenase family 3 member A2 Aldehyde dehydrogenase Aldehyde dehydrogenase Alkaline ceramidase Alkaline ceramidase Alkaline ceramidase Phospholipid phosphatase 1 Phospholipid phosphatase 3 Sphingosine-1-phosphate phosphatase 1 Sphingosine-1-phosphate phosphatase 2 sphinganine-1-phosphate aldolase	A0A287A341 A0A287ABN3 A0A287BBJ7 A0A287BEZ7 A0A287BQZ5 A0A5G2QIU3 A0A5G2R1U7 I3L5T1 I6L6E1 P60588 V9GZ89	ACER1 ACER2 ACER3 ALDH3A2 ALDH3B1 ALDH3B2 LPP1 PLPP1 PLPP3 PPAP2A SGPL1 SGPP1 SGPP2	Sus scrofa (pig)
Intestinal hexose absorption	Sodium/glucose cotransporter 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 5	A0A287A2X6 A0A8W4FPK7 F1RLV1 O62786	GLUT2 SLC2A2 SLC2A5 SLC5A1	Sus scrofa (pig)	G58161NS G93924TT
RHOBTB1 GTPase cycle	COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 4 Cleavage and polyadenylation specific factor 7 Cullin 3 E3 ubiquitin-protein ligase RBBP6 G protein pathway suppressor 1 Heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1 Phosphodiesterase Rho related BTB domain containing 1 Rho-associated protein kinase 2 Rho-associated protein kinase Serine and arginine repetitive matrix 1 Serine/threonine kinase 38 T-complex protein 1 subunit beta TRA2B Thioredoxin like 1 Unconventional myosin-VI Vimentin	A0A287A2J9 A0A287AAK1 A0A287AL07 A0A287AV47 A0A287B475 A0A5G2QIS7 A0A5G2QW31 A0A5K1ULP5 A7Y521 D0G0C8 F1RKQ8 F1RY93 F1S1X9 I3LK71 K9IVT3 M3TYT0 P02543 Q06AA7	CCT2 COPS2 COPS4 CPSF7 CUL3 GPS1 HNRNPC MYO6 PDE5A RBBP6 RHOBTB1 ROCK1 ROCK2 SRRM1 STK38 TRA2B TXNL1 VIM	Sus scrofa (pig)
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Calmodulin 3 Inositol polyphosphate-5-phosphatase J Inositol-tetrakisphosphate 1-kinase Kinase Kinase Kinase Phosphatase and tensin homolog Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phosphoinositide phospholipase C Phospholipase D family member 4 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphoinositide 5-phosphatase phosphoinositide 5-phosphatase	A0A287A266 A0A287ABR0 A0A287AG06 A0A287B4R5 A0A287B624 A0A287BL45 A0A287BSY0 A0A480K9S0 A0A5G2QKY7 A0A5G2QSN6 A0A5G2QWK6 A0A5G2RAE7 A0A8W4FCN0 A0A8W4FM71 F1RHA5 F1RPC4 F1RQ08 F1RR07 F1S475 F1S9V1 F1SDV6 F1SQZ0 F2Z5H1 I3LUM3 Q8SPR7	CALM3 INPP5D INPP5J INPPL1 ITPK1 ITPKA ITPKC OCRL PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCH1 PLCH2 PLCZ1 PLD4 PTEN SYNJ1	Sus scrofa (pig)
EGFR interacts with phospholipase C-gamma	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Amphiregulin Betacellulin Epiregulin Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Transforming growth factor alpha	A0A287A231 A0A287A6I2 A0A287AZM9 A0A5G2QBP1 F1SDV6 F1SLD3 Q01580 Q9BDH4	AREG BTC DTR EGF EGFR EREG HBEGF HEGFL PLCG1 TGFA	Sus scrofa (pig)
Signaling by EGFR	Amphiregulin Angio associated migratory cell protein Betacellulin Epiregulin Family with sequence similarity 83 member A Family with sequence similarity 83 member B Family with sequence similarity 83 member D Leucine rich repeats and immunoglobulin like domains 1 Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Transforming growth factor alpha Tyrosine-protein kinase	A0A287A231 A0A287A6I2 A0A287AZM9 A0A5G2QBP1 A0A5G2QD31 F1RR13 F1RZW2 F1SFR8 F1SLD3 F1SRY9 K7GPR7 Q01580 Q9BDH4	AAMP AREG BTC DTR EGF EGFR EREG FAM83A FAM83B FAM83D HBEGF HEGFL LRIG1 SRC TGFA	Sus scrofa (pig)
GAB1 signalosome	Amphiregulin Betacellulin Epiregulin GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Transforming growth factor alpha Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A287A231 A0A287A6I2 A0A287AZM9 A0A480LMF4 A0A5G2QBP1 A0A5G2RG25 A0A5K1UB41 B6E241 F1RXA1 F1SJ27 F1SKR9 F1SLD3 K7GMT0 K7GPR7 Q01580 Q9BDH4	AREG BTC CSK DTR EGF EGFR EREG GAB1 GRB2 HBEGF HEGFL PAG1 PIK3CA PIK3R1 PTPN11 PXN SRC TGFA	Sus scrofa (pig)
Ion transport by P-type ATPases	ATPase 13A1 ATPase Na+/K+ transporting subunit alpha 3 ATPase cation transporting 13A2 Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium/calmodulin-dependent protein kinase type II subunit delta Calmodulin 3 Cardiac phospholamban Cation-transporting ATPase Cation-transporting ATPase FXYD domain-containing ion transport regulator P-type Cu(+) transporter PDZ domain-containing protein 11 Phospholemman Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Potassium-transporting ATPase subunit beta Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Sorcin calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase	A0A287A226 A0A287AFK3 A0A287AL21 A0A287APC7 A0A287B705 A0A287B7D1 A0A287B7S6 A0A287BAN5 A0A287BCC5 A0A5G2Q8V3 A0A5G2QCQ9 A0A5G2QQF7 A0A5G2QSB0 A0A5G2QWK6 A0A5G2RAC3 A0A5G2RDL8 A0A5K1U0J0 A0A5K1VCX5 A0A8W4FK37 A0A8W4FN13 A0A8X9AEX2 D2WKD8 F1RL74 F1RM59 F1RQ73 F1S340 F1S3S6 F1SDH8 F1SFG8 F1SM35 F1SNN7 F1SQH3 F1ST41 F1SUR9 I3LIK9 I3LMB3 I3LN55 I3LUR3 K7GQ24 O77696 P05027 P11607 P18434 P61013 Q6QA76 Q95266	ATP10A ATP10B ATP10D ATP11A ATP11B ATP11C ATP12A ATP13A1 ATP13A2 ATP13A4 ATP13A5 ATP1A2 ATP1A3 ATP1B1 ATP1B2 ATP1B3 ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 ATP2C1 ATP2C2 ATP4A ATP4B ATP7A ATP8A1 ATP8A2 ATP8B1 ATP8B2 ATP8B3 ATP8B4 ATP9A ATP9B CALM3 CAMK2A CAMK2B CAMK2D CAMK2G FXYD1 FXYD6 PDZD11 PDZK11 PLM PLN SRI	Sus scrofa (pig)
SUMOylation of intracellular receptors	Androgen receptor Bile acid receptor isoform 4 E3 SUMO-protein ligase PIAS1 isoform 2 E3 SUMO-protein ligase PIAS3 Estrogen receptor Glucocorticoid receptor Histone deacetylase Mineralocorticoid receptor Nuclear receptor subfamily 1 group H member 2 Nuclear receptor subfamily 1 group H member 3 Nuclear receptor subfamily 1 group I member 2 Nuclear receptor subfamily 5 group A member 2 Peroxisome proliferator-activated receptor alpha Progesterone receptor Protein inhibitor of activated STAT 4 RAR related orphan receptor A Retinoic acid receptor RXR Retinoic acid receptor alpha SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Small ubiquitin-related modifier 2 Small ubiquitin-related modifier Steroidogenic factor 1 Thyroid hormone receptor alpha Thyroid hormone receptor beta Vitamin D3 receptor	A0A287A1X6 A0A287AD21 A0A287B3I8 A0A287B660 A0A287BCG5 A0A287BP95 A0A287BQF9 A0A288CG33 A0A480PNE7 A0A5G2R5L5 A0A8W4F919 A3RGC1 A7WLH8 F1RH38 F1RTM6 F1SDD9 F1SM76 F1SV76 F6Q6I2 I3LJA1 I3LNY9 I3LSZ1 O97716 P61958 P79387 Q29040	AR ESR ESR1 FTZF1 HDAC4 NR1A1 NR1H2 NR1H3 NR1H4 NR1I1 NR1I2 NR3A1 NR3C1 NR3C2 NR5A1 NR5A2 PGR PIAS1 PIAS3 PIAS4 PPARA RARA RORA RXRA SMT3A SMT3H2 SUMO1 SUMO2 SUMO3 THRA THRB UBE2I VDR	Sus scrofa (pig)
Orexin and neuropeptides FF and QRFP bind to their respective receptors	Hypocretin neuropeptide precursor Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Pyroglutamylated RFamide peptide receptor	A0A287A138 F1RUN6 F1S1T5 F1SUD0 O62809 O77668	HCRT HCRTR1 HCRTR2 NPFFR1 NPFFR2 ORX OX PPOX QRFPR	Sus scrofa (pig)
Prostanoid ligand receptors	Prostacyclin receptor Prostaglandin D2 receptor Prostaglandin E receptor 1 Prostaglandin E receptor 2 Prostaglandin E2 receptor EP3 subtype Prostaglandin E2 receptor EP4 subtype Prostaglandin F2-alpha receptor Thromboxane A2 receptor	A0A287A102 F1SCF7 F1SFF0 F1SFF2 I3LLK4 I3LT62 P50131 Q95L06	PTGDR PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR TBXA2R fp	Sus scrofa (pig)
Digestion of dietary carbohydrate	Alpha-amylase Alpha-amylase Alpha-amylase Lactase-phlorizin hydrolase Lactase-phlorizin hydrolase Maltase-glucoamylase Sucrase-isomaltase chitinase chitinase	A0A287A042 A0A8W4F9F9 A0A8W4FII7 F1S574 F1S7U2 I3LI68 I3LL32 I3LLP2 I3LSA5	AMY2 CHIA CHIT1 LCT LOC100153446 LOC100521789 LOC100625897 MGAM SI	Sus scrofa (pig)	G58161NS G74621DY G80384UV G93924TT G96370VA

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