PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Database | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Unknown
|
unnamed ligand
|
Oligosaccharides
|
Murine small plaque
|
NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc
|
Binding
|
||
Unknown
|
Sialic acid (α2,6)
|
Saccharides
|
Most organs including the central nervous system/heart/liver
|
NeuAc(a2-6)
|
Binding
|
||
Adhesins
|
terminal Gal(3SO4) β1- residues
|
Sulfoglycosphingolipids
|
Human lung, Human trachea
|
Gal(3SO4)(b
|
Binding
|
||
FHA (filamentous hemagglutinin)
|
Sulfatide (CSE)
|
Sulfoglycosphingolipids
|
Cell surface
|
HSO3(-3)Gal(b1-1)Cer
|
Binding
|
||
Adhesins
|
Sulfatide (CSE)
|
Sulfoglycosphingolipids
|
Erythrocytes
|
HSO3(-3)Gal(b1-1)Cer
|
Binding
|
||
Adhesins
|
Sulfatide (CSE)
|
Sulfoglycosphingolipids
|
Human gastric mucosa
|
HSO3(-3)Gal(b1-1)Cer
|
Binding
|
||
Unknown
|
Sulfo-lactosylceramide (SM3)
|
Sulfoglycosphingolipids
|
Human colon adenocarcinoma cells (WiDr )
|
HSO3(-3)Gal(b1-4)Glc(b1-1)Cer
|
Binding
|
||
gp120
|
Sulfatide (CSE)
|
Sulfoglycosphingolipids
|
Human U373-MG glioma and SK-N-MC neuroblastoma cells, Human colon epithelial HT29 cells
|
HSO3(-3)Gal(b1-1)Cer
|
Binding
|
||
Neutrophil-activating proteins (150-kDa)
|
Sulfatide (CSE)
|
Sulfoglycosphingolipids
|
Human meconium
|
HSO3(-3)Gal(b1-1)Cer
|
Binding
|
||
Envelope glycoprotein gp120
|
Galactosyl sulfatide
|
Sulfoglycosphingolipids
|
Neural receptor
|
HSO3(-3)Gal(b1-1)Cer
|
Binding
|
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01