Genes / Proteins / Lipids
GlyCosmos Genes

Integrated list of glycan-related genes extracted KEGG GENES Database, UniProt, GlycoGene Database (GGDB), Plant GARDEN and FlyGlycoDB. Glycan-related genes including glycosyltransferase, hydrolase activity (acting on glycosyl bonds), carbohydrate metabolic process, etc .

GlycoGene Database (GGDB)

GGDB is a database which includes genes associated with glycan synthesis such as glycosyltransferase, sugar nucleotide synthases, sugar-nucleotide transporters, and sulfotransferases.

Plant GARDEN

PlantGARDEN (Genome And Resource Database Entry) is a portal site that curates genome and marker information of various plant species. This is a list of the glycogenes computationally extracted from all plant genomes in PlantGARDEN.

Glyco-Disease Genes Database (GDGDB)

GDGDB is a database of glycan-related diseases and their responsible genes.

GlycoNAVI Genes

GlycoNAVI-Genes is dataset of gene informtion. This is the content of GlycoNAVI.

FlyGlycoDB

FlyGlycoDB is a database that summarizes genetic study results on Drosophila . In FlyGlycoDB, glycan-related Drosophila genes for which functions have been identified are currently registered, including genes for which activity has been confirmed by analysis using RNAi silencing (Nishihara et al. 2007, 2010; Yamamoto et al. 2015) and genes obtained from CAZy (Lombard et al. 2014), which is a database for carbohydrate-active enzymes.

LIPID MAPS

Lipid-related genes and proteins from LIPID MAPS Proteome Database (LMPD).

Alliance of Genome Resources

Alliance of Genome Resources is a gene dataset, which contains curated genome information essential for the understanding of the genetics and genomic basis of human biology, health and disease. All data is retrieved from six major model organism databases and the Gene Ontology including FlyBase, Mouse Genome Database (MGI), Rat Genome Database (RGD), Saccharomyces Genome Database (SGD), WormBase, Zebrafish Information Network (ZFIN), and the GO Consortium. In GlyCosmos, only glycan-related disease information has been extracted from Alliance of Genome Resources.

DisGeNET

DisGeNET is a knowledge management platform that integrates and standardizes the data of genes and mutations related to diseases from multiple sources. It covers entire range of human disease.

CAZy

The CAZy database describes the families of structurally-related catalytic and carbohydrate-binding modules (or functional domains) of enzymes that degrade, modify, or create glycosidic bonds.

GlyCosmos Glycoproteins

Integrated list of glycoproteins extracted from UniProt and annotated with glycosylation data from GlyGen, GlyConnect, GlycoProtDB and The O-GlcNAc Database. For each entry, information such as glycosylation site, glycans, diseases, 3D structures, and pathway information are available.

GlyCosmos Lectins

Integrated list of Lectins, including proteins with carbohydrate binding function obtained from UniProt and lectin data from Lectin Frontier DataBase (LfDB), UniLectin and CarboGrove. Glycosylation site information, along with glycan-binding patterns are also integrated where available.

GlycoProtDB

GlycoProtDB is a glycoprotein database providing information of Asn (N)-glycosylated proteins and their glycosylated site(s), which were constructed by employing a bottom-up strategy using actual glycopeptide sequences identified by LC/MS-based glycoproteomic technologies.

Lectin Frontier DataBase (LfDB)

LfDB provides quantitative interaction data in terms of the affinity constants (Ka) of a series of lectins toward a panel of pyridylaminated (PA) glycans obtained by an automated frontal affinity chromatography with fluorescence detection (FAC-FD) system.

GlycoNAVI Proteins

GlycoNAVI-Proteins is dataset of glycan and protein information. This is the content of GlycoNAVI.

GlycoNAVI Lectins

GlycoNAVI-Lectins is a subset of GlycoNAVI-Proteins, a dataset of glycan and protein information, which is the content of GlycoNAVI. This is the content of GlycoNAVI.


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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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GlyCosmos Portal v4.0.0

Last updated: August 19, 2024