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Standards Ontologies Notations
rheumatic heart disease

Summary
Synonym
  • rheumatic carditis
Definition
A heart valve disease that is characterized by repeated inflammation with fibrinous repair caused by an autoimmune reaction to Group A beta-hemolytic streptococci (GAS) that results in valvular damage. The cardinal anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords.
Super Class
heart valve disease
External Links
Disease Ontology
DOID:0050827
Mondo Disease Ontology
MeSH
Related Genes
Displaying all 2 entries
Gene ID Gene Symbol Description Source
2597 GAPDH glyceraldehyde-3-phosphate dehydrogenase
30835 CD209 CD209 molecule
Displaying 1 entry
Gene ID Gene Symbol Description Source
14433 Gapdh glyceraldehyde-3-phosphate dehydrogenase
Displaying 1 entry
Gene ID Gene Symbol Description Source
24383 Gapdh glyceraldehyde-3-phosphate dehydrogenase
Displaying all 2 entries
Gene ID Gene Symbol Description Source
32545 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2
35728 Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
Displaying all 3 entries
Gene ID Gene Symbol Description Source
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
180601 gpd-3 Glyceraldehyde-3-phosphate dehydrogenase 3
Displaying all 3 entries
Gene ID Gene Symbol Description Source
853106 TDH3 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
853395 TDH1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
853465 TDH2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024