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MIRAGE
X-linked spermatogenic failure 8

Summary
Synonym
  • SPGFX8
Definition
A spermatogenic failure characterized by sperm with head and midpiece defects, deformed and detached acrosomes, and markedly reduced progressive motility that has_material_basis_in hemizygous mutation in the CYLC1 gene on chromosome Xq21.1.
Super Class
X-linked monogenic disease spermatogenic failure
Disease Ontology
DOID:0070599
Related Genes
Displaying 1 entry
Gene ID Gene Symbol Description Source
1538 CYLC1 cylicin 1
Related Glycoprotein
Displaying 1 entry
UniProt ID Protein Name Source
P35663 Cylicin-1
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025