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Standards Ontologies Notations
Alzheimer's disease

Summary
Synonym
  • Alzheimer disease
  • Alzheimers dementia
Definition
A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.
Super Class
tauopathy
External Links
Disease Ontology
DOID:10652
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 111 - 120 of 350 in total
Gene ID Gene Symbol Description Source
3339 HSPG2 heparan sulfate proteoglycan 2
3356 HTR2A 5-hydroxytryptamine receptor 2A
3383 ICAM1 intercellular adhesion molecule 1
3417 IDH1 isocitrate dehydrogenase (NADP(+)) 1
3418 IDH2 isocitrate dehydrogenase (NADP(+)) 2
3425 IDUA alpha-L-iduronidase
3481 IGF2 insulin like growth factor 2
3482 IGF2R insulin like growth factor 2 receptor
3554 IL1R1 interleukin 1 receptor type 1
3556 IL1RAP interleukin 1 receptor accessory protein
Displaying entries 11 - 20 of 24 in total
Gene ID Gene Symbol Description Source
16195 Il6st interleukin 6 signal transducer
16333 Ins1 insulin I
16334 Ins2 insulin II
16846 Lep leptin
18534 Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic
18708 Pik3r1 phosphoinositide-3-kinase regulatory subunit 1
19013 Ppara peroxisome proliferator activated receptor alpha
19017 Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
21898 Tlr4 toll-like receptor 4
21926 Tnf tumor necrosis factor
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
24333 Eno1 enolase 1
24383 Gapdh glyceraldehyde-3-phosphate dehydrogenase
24483 Igf2 insulin-like growth factor 2
24505 Ins1 insulin 1
24506 Ins2 insulin 2
24835 Tnf tumor necrosis factor
25239 Apod apolipoprotein D
25513 Pik3r1 phosphoinositide-3-kinase regulatory subunit 1
25591 Parp1 poly (ADP-ribose) polymerase 1
25608 Lep leptin
Displaying all 9 entries
Gene ID Gene Symbol Description Source
31248 sgg shaggy
31293 N Notch
32545 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2
33351 Eno Enolase
35728 Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1
37131 Pepck1 Phosphoenolpyruvate carboxykinase 1
38973 se sepia
43222 Tl Toll
3355109 Parp1 Poly-(ADP-ribose) polymerase 1
Displaying all 4 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
406367 gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
560788 parp1 poly (ADP-ribose) polymerase 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
380259 gapdh.S glyceraldehyde-3-phosphate dehydrogenase S homeolog Xenopus laevis (African clawed frog)
380298 eno1.S enolase 1 S homeolog Xenopus laevis (African clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
174423 enol-1 Enolase
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
180601 gpd-3 Glyceraldehyde-3-phosphate dehydrogenase 3
183000 gsto-1 Glutathione transferase omega-1
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying all 9 entries
Gene ID Gene Symbol Description Source
850666 GTT2 glutathione transferase GTT2
853106 TDH3 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
853169 ENO1 phosphopyruvate hydratase ENO1
853395 TDH1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
853465 TDH2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
854575 ERR1 phosphopyruvate hydratase ERR1
855373 ERR3 phosphopyruvate hydratase ERR3
855848 ERR2 phosphopyruvate hydratase ERR2
856579 ENO2 phosphopyruvate hydratase ENO2
Related Glycoprotein
Displaying entries 251 - 252 of 252 in total
UniProt ID Protein Name Source
Q9Y625 Glypican-6
Q9Y6A2 Cholesterol 24-hydroxylase
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024